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The map label for this gene is 50085523

Identifier: 50085523

GI number: 50085523

Start: 2402581

End: 2404131

Strand: Reverse

Name: 50085523

Synonym: ACIAD2438

Alternate gene names: NA

Gene position: 2404131-2402581 (Counterclockwise)

Preceding gene: 50085525

Following gene: 50085522

Centisome position: 66.81

GC content: 38.62

Gene sequence:

>1551_bases
ATGTTAGAAGAAGATAAAGACTTACATACAATAAGTGAGCACTATATGAAAGAAAAAACGACAAATGTTTTGTTATCCCA
GCCTTCGTTTCTTGACCAGCTCAGTGTAAGCACAAATCTTTTTGAGCAACTTAAATCAAAGTTTTTCAATGAGATGCTGG
ATGATGTAACGTCAAACGGTGAAGCATCAAAAAAGATTGAACAATGGCTATCGACCCATACTTTAGAGGAACTTAAACAA
CTTAACTTAAATGCAAAACAACATTTTCTATATGAAGGCATTACATTTACGGTTTATGGTGATGATGAAGGAACCGAGCG
AACTATTCCTTTCGATTTAATCCCGCGTGTCATTGAAAAAAAACAATGGGAGAAAATCTCAAGCGGATGTGAACAACGTG
TTAAAGCACTCAACTTATTTTTAGATGATATTTATCATAATCAACTTATTCTCAAAGAAGGCATTGTTCCTCAGATACAA
GTCATGACCCATGAGGCTTTTCAACCTCACATGCTGAATCATTCCCTCAAAGGTAAGGTATATTCACAAATTAGTGGGAT
TGATATTATTCGGGATGGCAAAGGTGAATTTTTTGTTTTGGAAGATAATTTAAGAACACCATCAGGTGTGTCTTACATGC
TTGAAAGTCGAAAAATTAGCAAGAAACTCATGCCTGAACTCTGTGTTTCAAATAAGCTACATGATATTGAACAATATCCA
ACAGTACTCAGAGACATATTAGCGGAAAATGCATTTGTGGATAATCCGTTTATTGTAGTGTTGACCCCAGGACGATTTAA
CAGTGCCTATTATGAGCATGCTTTTTTAGCTCGTGAAATGGGTGTGCCTTTGGTGACGAGTCGTGATCTATTTGTAGAAA
ATGACAAGGTTTATGCCAAGACTGTTCGTGGTCGTCAGCGCGTTGATGTGATCTATCGCCGTGTTGATGATGCATTCTTA
GACCCGTTAACGTTCCGTCCAGACAGTACACTCGGTGTGCCAGGATTAATGTCTGCTTATTTGCAAAATCAGGTCGTGAT
TGCAAATGCACCAGGTACAGGTGTCGCAGATGATAAATCCATTTACCCCTATGTAGATGATATGATTAAATATTATCTTA
ATGAAACGCCTATTCTAAAAAATGTACCCACTTACCAATGCCGTTTAGATGAGCATCTGGATTATGTAGTAAGTAATCTG
GCAAATCTGGTGGTAAAAGAAGCGCAAGGCTCGGGTGGATATGGCATGTTGATTGGTCCTAAAGCCGAACAGCATGAAAT
TCATGAATTTAGAGAAAAAATTCTAGCACATCCACATTTATACATTGCCCAACCTACACTTGATCTATCTGTTGCACCAA
CACTTACTCAAGATGGTATTGCAGAGAGACATATCGATCTTCGTCCTTTCGTGCTGACATCGCCTTACCGTACAGAAATT
GTACCTGGTGGTTTAACACGTGTGGCCATGAAAGAAGGTTCTTTAGTGGTCAATTCTTCACAGGGTGGTGGTATTAAAGA
TACGTGGGTTGTGGACGCACTACATTCCTAA

Upstream 100 bases:

>100_bases
TTTAAATCTAGGTTCTTTATTGAAATACAAAAATAGATTCGAACAAATGGCACTATATTTGCAATGTATAAAATGAGTAA
ACGAAAAAGGCGAGGTCTGT

Downstream 100 bases:

>100_bases
CTTAGGTATTAGAAAAAGGAAGGAACTTATGATTTTACTTAGTTCAAATGCAAATAATATTTTTTGGTTAGGTCGTTATT
TGATGCGTATTCAGTACCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MLEEDKDLHTISEHYMKEKTTNVLLSQPSFLDQLSVSTNLFEQLKSKFFNEMLDDVTSNGEASKKIEQWLSTHTLEELKQ
LNLNAKQHFLYEGITFTVYGDDEGTERTIPFDLIPRVIEKKQWEKISSGCEQRVKALNLFLDDIYHNQLILKEGIVPQIQ
VMTHEAFQPHMLNHSLKGKVYSQISGIDIIRDGKGEFFVLEDNLRTPSGVSYMLESRKISKKLMPELCVSNKLHDIEQYP
TVLRDILAENAFVDNPFIVVLTPGRFNSAYYEHAFLAREMGVPLVTSRDLFVENDKVYAKTVRGRQRVDVIYRRVDDAFL
DPLTFRPDSTLGVPGLMSAYLQNQVVIANAPGTGVADDKSIYPYVDDMIKYYLNETPILKNVPTYQCRLDEHLDYVVSNL
ANLVVKEAQGSGGYGMLIGPKAEQHEIHEFREKILAHPHLYIAQPTLDLSVAPTLTQDGIAERHIDLRPFVLTSPYRTEI
VPGGLTRVAMKEGSLVVNSSQGGGIKDTWVVDALHS

Sequences:

>Translated_516_residues
MLEEDKDLHTISEHYMKEKTTNVLLSQPSFLDQLSVSTNLFEQLKSKFFNEMLDDVTSNGEASKKIEQWLSTHTLEELKQ
LNLNAKQHFLYEGITFTVYGDDEGTERTIPFDLIPRVIEKKQWEKISSGCEQRVKALNLFLDDIYHNQLILKEGIVPQIQ
VMTHEAFQPHMLNHSLKGKVYSQISGIDIIRDGKGEFFVLEDNLRTPSGVSYMLESRKISKKLMPELCVSNKLHDIEQYP
TVLRDILAENAFVDNPFIVVLTPGRFNSAYYEHAFLAREMGVPLVTSRDLFVENDKVYAKTVRGRQRVDVIYRRVDDAFL
DPLTFRPDSTLGVPGLMSAYLQNQVVIANAPGTGVADDKSIYPYVDDMIKYYLNETPILKNVPTYQCRLDEHLDYVVSNL
ANLVVKEAQGSGGYGMLIGPKAEQHEIHEFREKILAHPHLYIAQPTLDLSVAPTLTQDGIAERHIDLRPFVLTSPYRTEI
VPGGLTRVAMKEGSLVVNSSQGGGIKDTWVVDALHS
>Mature_516_residues
MLEEDKDLHTISEHYMKEKTTNVLLSQPSFLDQLSVSTNLFEQLKSKFFNEMLDDVTSNGEASKKIEQWLSTHTLEELKQ
LNLNAKQHFLYEGITFTVYGDDEGTERTIPFDLIPRVIEKKQWEKISSGCEQRVKALNLFLDDIYHNQLILKEGIVPQIQ
VMTHEAFQPHMLNHSLKGKVYSQISGIDIIRDGKGEFFVLEDNLRTPSGVSYMLESRKISKKLMPELCVSNKLHDIEQYP
TVLRDILAENAFVDNPFIVVLTPGRFNSAYYEHAFLAREMGVPLVTSRDLFVENDKVYAKTVRGRQRVDVIYRRVDDAFL
DPLTFRPDSTLGVPGLMSAYLQNQVVIANAPGTGVADDKSIYPYVDDMIKYYLNETPILKNVPTYQCRLDEHLDYVVSNL
ANLVVKEAQGSGGYGMLIGPKAEQHEIHEFREKILAHPHLYIAQPTLDLSVAPTLTQDGIAERHIDLRPFVLTSPYRTEI
VPGGLTRVAMKEGSLVVNSSQGGGIKDTWVVDALHS

Specific function: Unknown

COG id: COG2308

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis RV2411c [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007297
- InterPro:   IPR007302
- InterPro:   IPR016450 [H]

Pfam domain/function: PF04169 DUF404; PF04174 DUF407 [H]

EC number: NA

Molecular weight: Translated: 58519; Mature: 58519

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEEDKDLHTISEHYMKEKTTNVLLSQPSFLDQLSVSTNLFEQLKSKFFNEMLDDVTSNG
CCCCCCHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EASKKIEQWLSTHTLEELKQLNLNAKQHFLYEGITFTVYGDDEGTERTIPFDLIPRVIEK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEECEEEEEEECCCCCCCCCCHHHHHHHHHH
KQWEKISSGCEQRVKALNLFLDDIYHNQLILKEGIVPQIQVMTHEAFQPHMLNHSLKGKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEHHCCCCHHHCCCCCCHH
YSQISGIDIIRDGKGEFFVLEDNLRTPSGVSYMLESRKISKKLMPELCVSNKLHDIEQYP
HHHHCCCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TVLRDILAENAFVDNPFIVVLTPGRFNSAYYEHAFLAREMGVPLVTSRDLFVENDKVYAK
HHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEECCCEEEECCCCHHH
TVRGRQRVDVIYRRVDDAFLDPLTFRPDSTLGVPGLMSAYLQNQVVIANAPGTGVADDKS
HHCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCC
IYPYVDDMIKYYLNETPILKNVPTYQCRLDEHLDYVVSNLANLVVKEAQGSGGYGMLIGP
CCHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
KAEQHEIHEFREKILAHPHLYIAQPTLDLSVAPTLTQDGIAERHIDLRPFVLTSPYRTEI
CCCHHHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCCCHHHHCCCCCCEEEECCCCCCC
VPGGLTRVAMKEGSLVVNSSQGGGIKDTWVVDALHS
CCCCHHEEEEECCCEEEECCCCCCCCHHHHHHECCC
>Mature Secondary Structure
MLEEDKDLHTISEHYMKEKTTNVLLSQPSFLDQLSVSTNLFEQLKSKFFNEMLDDVTSNG
CCCCCCHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EASKKIEQWLSTHTLEELKQLNLNAKQHFLYEGITFTVYGDDEGTERTIPFDLIPRVIEK
HHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEECEEEEEEECCCCCCCCCCHHHHHHHHHH
KQWEKISSGCEQRVKALNLFLDDIYHNQLILKEGIVPQIQVMTHEAFQPHMLNHSLKGKV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEEEEEHHCCCCHHHCCCCCCHH
YSQISGIDIIRDGKGEFFVLEDNLRTPSGVSYMLESRKISKKLMPELCVSNKLHDIEQYP
HHHHCCCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TVLRDILAENAFVDNPFIVVLTPGRFNSAYYEHAFLAREMGVPLVTSRDLFVENDKVYAK
HHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEECCCEEEECCCCHHH
TVRGRQRVDVIYRRVDDAFLDPLTFRPDSTLGVPGLMSAYLQNQVVIANAPGTGVADDKS
HHCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCC
IYPYVDDMIKYYLNETPILKNVPTYQCRLDEHLDYVVSNLANLVVKEAQGSGGYGMLIGP
CCHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
KAEQHEIHEFREKILAHPHLYIAQPTLDLSVAPTLTQDGIAERHIDLRPFVLTSPYRTEI
CCCHHHHHHHHHHHHCCCCEEEECCCCCEEECCCCCCCCHHHHCCCCCCEEEECCCCCCC
VPGGLTRVAMKEGSLVVNSSQGGGIKDTWVVDALHS
CCCCHHEEEEECCCEEEECCCCCCCCHHHHHHECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1368738; 8590279; 8905231 [H]