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The map label for this gene is alr [H]

Identifier: 50085519

GI number: 50085519

Start: 2399265

End: 2400341

Strand: Direct

Name: alr [H]

Synonym: ACIAD2434

Alternate gene names: 50085519

Gene position: 2399265-2400341 (Clockwise)

Preceding gene: 50085518

Following gene: 50085524

Centisome position: 66.67

GC content: 39.55

Gene sequence:

>1077_bases
GTGCGCCATGCAACAGTTTATATTGATCGCCAAGCGCTTCGATATAATTTAAACCGTGTCAAACAACTTGCGCCACATGC
AAAAATTGTAAGTATGGTCAAAGCCAATGCTTATGGACATGGAATCAAAGACTGTTTAGCAGCCTTAGAAACGACAGATT
CCTTTGGAGTCGCCTGCCTTGCTGAAGCATTAGAAATTCGTGATGAAGGATATACTCAATCCATTACATTAATTGAAGGC
GTATTCAGTCAAGATGAAATGCCAATCGTCATTGAAAAAAATCTTGAATGTGTCGTACATCACGCTCAACAAATTAAATG
GTTATTGGAATATAAAACACAATATATCACTCAGAAACTCAAAGTCTGGATTAAGCTGAATAGTGGAATGAATCGTCTAG
GGTTTAAGCCTGATGAAATTATTGAAGTCATACAGCAATTGCAACATCAAGGTTTTCACTGTGTACTCACCATGCATTTT
GCCAATGCAGATGTACCTGATCACCCTATGAATCAACGCCAGATTGATCAATTAATAACAATTAAAACAGCTTGTGCTCC
AATAGAAATTTCATGTTGTAATTCTGCTGCAATCTTCAATTGGCCAGAATTACATTTCGATTATGTAAGACCTGGAATTA
TGCTATACGGCGCCAGTCCTTTCGCAGAACAAAATATTCATCAGCTTGATTTAAAACCTGTTATGCGTTTTACCGCTCAT
ATCATGGCTCTAAATACAATCAAGGCAGGTGAACATATCGGTTACGGCTCTCTTTATACCGCTAAAACGGACATGACTGT
TGCTATTGTTTCAATCGGCTATGGAGATGGTTACCCACGAGCGTTTATAGCCCAGAATTTTGTAGCTTTGGGGCAGCAAT
TATTCCCGATTGTAGGCCGAGTAAGTATGGATATGCTTGCAATTGATGTGACTGATCGAGATATAGCGATTGATACAGAA
ATTGAACTATGGGGGCACACAAGACTGGTCGATGAAGTGGCATCAGCGAACGGGACGATCGGTTATGAATTGCTTTGTCG
TCTGAGCAACCGCCCTATACGTAAAGTTATTTCATAA

Upstream 100 bases:

>100_bases
TGAAGGTCAATATACTCGGTTTAGTAACCTCTCACCTGAATATTACAGTCAGTATGATGACGAAGAATAAATTACATTAC
TATACACAGGAGTAATCAGG

Downstream 100 bases:

>100_bases
TTCATCATAAAAAGCCGTATCAAAAAGATTTGCTACGGCTTTAAACTTATATTGTCTAGCCTACTATTTGCTTTAAATAT
TTCTATTCCAGATAGTCTTC

Product: alanine racemase 1, biosynthetic

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MRHATVYIDRQALRYNLNRVKQLAPHAKIVSMVKANAYGHGIKDCLAALETTDSFGVACLAEALEIRDEGYTQSITLIEG
VFSQDEMPIVIEKNLECVVHHAQQIKWLLEYKTQYITQKLKVWIKLNSGMNRLGFKPDEIIEVIQQLQHQGFHCVLTMHF
ANADVPDHPMNQRQIDQLITIKTACAPIEISCCNSAAIFNWPELHFDYVRPGIMLYGASPFAEQNIHQLDLKPVMRFTAH
IMALNTIKAGEHIGYGSLYTAKTDMTVAIVSIGYGDGYPRAFIAQNFVALGQQLFPIVGRVSMDMLAIDVTDRDIAIDTE
IELWGHTRLVDEVASANGTIGYELLCRLSNRPIRKVIS

Sequences:

>Translated_358_residues
MRHATVYIDRQALRYNLNRVKQLAPHAKIVSMVKANAYGHGIKDCLAALETTDSFGVACLAEALEIRDEGYTQSITLIEG
VFSQDEMPIVIEKNLECVVHHAQQIKWLLEYKTQYITQKLKVWIKLNSGMNRLGFKPDEIIEVIQQLQHQGFHCVLTMHF
ANADVPDHPMNQRQIDQLITIKTACAPIEISCCNSAAIFNWPELHFDYVRPGIMLYGASPFAEQNIHQLDLKPVMRFTAH
IMALNTIKAGEHIGYGSLYTAKTDMTVAIVSIGYGDGYPRAFIAQNFVALGQQLFPIVGRVSMDMLAIDVTDRDIAIDTE
IELWGHTRLVDEVASANGTIGYELLCRLSNRPIRKVIS
>Mature_358_residues
MRHATVYIDRQALRYNLNRVKQLAPHAKIVSMVKANAYGHGIKDCLAALETTDSFGVACLAEALEIRDEGYTQSITLIEG
VFSQDEMPIVIEKNLECVVHHAQQIKWLLEYKTQYITQKLKVWIKLNSGMNRLGFKPDEIIEVIQQLQHQGFHCVLTMHF
ANADVPDHPMNQRQIDQLITIKTACAPIEISCCNSAAIFNWPELHFDYVRPGIMLYGASPFAEQNIHQLDLKPVMRFTAH
IMALNTIKAGEHIGYGSLYTAKTDMTVAIVSIGYGDGYPRAFIAQNFVALGQQLFPIVGRVSMDMLAIDVTDRDIAIDTE
IELWGHTRLVDEVASANGTIGYELLCRLSNRPIRKVIS

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=350, Percent_Identity=42, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI1790487, Length=363, Percent_Identity=38.2920110192837, Blast_Score=253, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 40270; Mature: 40270

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHATVYIDRQALRYNLNRVKQLAPHAKIVSMVKANAYGHGIKDCLAALETTDSFGVACL
CCCEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHH
AEALEIRDEGYTQSITLIEGVFSQDEMPIVIEKNLECVVHHAQQIKWLLEYKTQYITQKL
HHHHHHHCCCCCEEEHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
KVWIKLNSGMNRLGFKPDEIIEVIQQLQHQGFHCVLTMHFANADVPDHPMNQRQIDQLIT
EEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHH
IKTACAPIEISCCNSAAIFNWPELHFDYVRPGIMLYGASPFAEQNIHQLDLKPVMRFTAH
HHHCCCCEEEEECCCCEECCCCCCCHHHCCCCEEEEECCCCCCCCCHHCCHHHHHHHHHH
IMALNTIKAGEHIGYGSLYTAKTDMTVAIVSIGYGDGYPRAFIAQNFVALGQQLFPIVGR
HHHHHEECCCCCCCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
VSMDMLAIDVTDRDIAIDTEIELWGHTRLVDEVASANGTIGYELLCRLSNRPIRKVIS
CEEEEEEEEECCCCEEEECEEEECCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MRHATVYIDRQALRYNLNRVKQLAPHAKIVSMVKANAYGHGIKDCLAALETTDSFGVACL
CCCEEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHH
AEALEIRDEGYTQSITLIEGVFSQDEMPIVIEKNLECVVHHAQQIKWLLEYKTQYITQKL
HHHHHHHCCCCCEEEHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
KVWIKLNSGMNRLGFKPDEIIEVIQQLQHQGFHCVLTMHFANADVPDHPMNQRQIDQLIT
EEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHH
IKTACAPIEISCCNSAAIFNWPELHFDYVRPGIMLYGASPFAEQNIHQLDLKPVMRFTAH
HHHCCCCEEEEECCCCEECCCCCCCHHHCCCCEEEEECCCCCCCCCHHCCHHHHHHHHHH
IMALNTIKAGEHIGYGSLYTAKTDMTVAIVSIGYGDGYPRAFIAQNFVALGQQLFPIVGR
HHHHHEECCCCCCCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
VSMDMLAIDVTDRDIAIDTEIELWGHTRLVDEVASANGTIGYELLCRLSNRPIRKVIS
CEEEEEEEEECCCCEEEECEEEECCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA