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The map label for this gene is nupX [H]

Identifier: 50085476

GI number: 50085476

Start: 2345375

End: 2346625

Strand: Reverse

Name: nupX [H]

Synonym: ACIAD2389

Alternate gene names: 50085476

Gene position: 2346625-2345375 (Counterclockwise)

Preceding gene: 50085477

Following gene: 50085475

Centisome position: 65.21

GC content: 41.25

Gene sequence:

>1251_bases
ATGTTTGAATATCGTGGTTTAATCGGTATTTTTATTCTTCTATTGATTGGATATATCTTTTCCAATAATCGAAGAATAAT
CAAAGTGAGAACGATTTTACCTGCTCTCGGTTTACAGTTTTTACTCGGGATCATTATTTTATATGTTCCAATGGGTAAGT
ATTTATTTGAACAGCTTGCTTCAGGCGTAAACCACGTGATTGGTTATGCGGATGCAGGCAGTGCATTTTTGTTTGGTGCG
TTAGTGGGCGACCAGATGAATACCGTATTTCATGGTGGCGGTTTTATTTTTGCACTTAAAGTTTTACCCACCATTATTTT
TGTAACTGCATTGATCGCCATTCTTTACTATCTCAAGATTATGACGATTTTTATCAAAGTTTTAGGTGGAATTTTTCAAA
AGGCTTTAGGGATTAGTAAAGTAGAATCTTTCGCTGCAGTGACGACTATTTTTATTGGTCAAAATGAATTGCCTGCTGCA
CTTCGACCATTTTTATTGCGTATGAATAAAAATGAGTTGTTTACAGTGATGTGTAGTGGAATGGCTGCTGTTTCTGGTTC
GGTGTTGGTGGGATACGCAGGTTTAGGTGTTCCTATGGAATATCTATTAGCAGCATCGTTAATGGCGATTCCAGGGGGTA
TTTTATTTGCCCGTTTGCTCAGTCCTGCTACCGAGCCATCAACAGTTGAAGTTACAGATCTTGAGTTTGGTGAACAGCGT
CCATCGAACATTATCGAAGCTGCAGCCAACGGTGCCATGATGGGTCTTAAAATTGCGGCAGGTGTCGGAACGGTCATTAT
GGTCTTTGTTGGCCTGCTGAGTCTGGTCAACGGTATTTTCGGCTTTGTGGGCGGATGGTTTGGCTATTCAGGCTTAAGTT
TAGATGCCATTTTCGGCTATATTTTGTCACCCTTGGCTTATGTCATGGGGGTTGATTGGAATGAGGCTCAACTTGCAGGT
GCATTGCTTGGACAAAAACTGGTCATTAACGAGTTTGTAGCTTATTTAAGTCTGTCACCACATCTGGCAGATCATACAAT
TTCGGCGCATACCGCTGCTATTATTTCTTTTGGTTTATGCGGCTTTGCAAACTTTAGTTCGATTGGTGTCGTGCTAGGGG
CGTTTGGTATGGTAGAACCAAAACTCACACCCGTACTCTCCAAACTGGCTGTGCGTGCTTTACTGGCAGCAACTTTATCA
AACCTGATGAGTGCAACCATTGCAGGAATTTGTCTTGGTTTTTCGATGTAA

Upstream 100 bases:

>100_bases
GCATGCTATCAGCAGAACAGTAGGTCAGTTTTGTTTAAGAAACTGATGAACTCAATGATCTGTGGCGTGAATGAGGTGTG
CTTATGTTACGGAGATAAGA

Downstream 100 bases:

>100_bases
AAGTGCCGATGTGTATTTGTTTTAATCTTTGATGTTAAATAAATACATACACCAATAGCCGTATTTTACGACATAAATAC
GGCTTATTTTTTGCTTAGAT

Product: NUP family transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MFEYRGLIGIFILLLIGYIFSNNRRIIKVRTILPALGLQFLLGIIILYVPMGKYLFEQLASGVNHVIGYADAGSAFLFGA
LVGDQMNTVFHGGGFIFALKVLPTIIFVTALIAILYYLKIMTIFIKVLGGIFQKALGISKVESFAAVTTIFIGQNELPAA
LRPFLLRMNKNELFTVMCSGMAAVSGSVLVGYAGLGVPMEYLLAASLMAIPGGILFARLLSPATEPSTVEVTDLEFGEQR
PSNIIEAAANGAMMGLKIAAGVGTVIMVFVGLLSLVNGIFGFVGGWFGYSGLSLDAIFGYILSPLAYVMGVDWNEAQLAG
ALLGQKLVINEFVAYLSLSPHLADHTISAHTAAIISFGLCGFANFSSIGVVLGAFGMVEPKLTPVLSKLAVRALLAATLS
NLMSATIAGICLGFSM

Sequences:

>Translated_416_residues
MFEYRGLIGIFILLLIGYIFSNNRRIIKVRTILPALGLQFLLGIIILYVPMGKYLFEQLASGVNHVIGYADAGSAFLFGA
LVGDQMNTVFHGGGFIFALKVLPTIIFVTALIAILYYLKIMTIFIKVLGGIFQKALGISKVESFAAVTTIFIGQNELPAA
LRPFLLRMNKNELFTVMCSGMAAVSGSVLVGYAGLGVPMEYLLAASLMAIPGGILFARLLSPATEPSTVEVTDLEFGEQR
PSNIIEAAANGAMMGLKIAAGVGTVIMVFVGLLSLVNGIFGFVGGWFGYSGLSLDAIFGYILSPLAYVMGVDWNEAQLAG
ALLGQKLVINEFVAYLSLSPHLADHTISAHTAAIISFGLCGFANFSSIGVVLGAFGMVEPKLTPVLSKLAVRALLAATLS
NLMSATIAGICLGFSM
>Mature_416_residues
MFEYRGLIGIFILLLIGYIFSNNRRIIKVRTILPALGLQFLLGIIILYVPMGKYLFEQLASGVNHVIGYADAGSAFLFGA
LVGDQMNTVFHGGGFIFALKVLPTIIFVTALIAILYYLKIMTIFIKVLGGIFQKALGISKVESFAAVTTIFIGQNELPAA
LRPFLLRMNKNELFTVMCSGMAAVSGSVLVGYAGLGVPMEYLLAASLMAIPGGILFARLLSPATEPSTVEVTDLEFGEQR
PSNIIEAAANGAMMGLKIAAGVGTVIMVFVGLLSLVNGIFGFVGGWFGYSGLSLDAIFGYILSPLAYVMGVDWNEAQLAG
ALLGQKLVINEFVAYLSLSPHLADHTISAHTAAIISFGLCGFANFSSIGVVLGAFGMVEPKLTPVLSKLAVRALLAATLS
NLMSATIAGICLGFSM

Specific function: Nucleoside transporter [H]

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI227116277, Length=419, Percent_Identity=33.890214797136, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI42542381, Length=420, Percent_Identity=33.3333333333333, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI11545853, Length=371, Percent_Identity=35.3099730458221, Blast_Score=223, Evalue=3e-58,
Organism=Escherichia coli, GI1788485, Length=412, Percent_Identity=62.1359223300971, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1788488, Length=412, Percent_Identity=61.8932038834951, Blast_Score=488, Evalue=1e-139,
Organism=Escherichia coli, GI1788737, Length=396, Percent_Identity=32.0707070707071, Blast_Score=188, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17560276, Length=392, Percent_Identity=31.3775510204082, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI71991794, Length=399, Percent_Identity=30.0751879699248, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI25146537, Length=206, Percent_Identity=30.0970873786408, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI45552517, Length=405, Percent_Identity=33.0864197530864, Blast_Score=241, Evalue=6e-64,
Organism=Drosophila melanogaster, GI19921868, Length=405, Percent_Identity=33.0864197530864, Blast_Score=241, Evalue=6e-64,
Organism=Drosophila melanogaster, GI45552519, Length=405, Percent_Identity=33.0864197530864, Blast_Score=241, Evalue=6e-64,
Organism=Drosophila melanogaster, GI281360430, Length=405, Percent_Identity=31.6049382716049, Blast_Score=201, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 44024; Mature: 44024

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEYRGLIGIFILLLIGYIFSNNRRIIKVRTILPALGLQFLLGIIILYVPMGKYLFEQLA
CCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
SGVNHVIGYADAGSAFLFGALVGDQMNTVFHGGGFIFALKVLPTIIFVTALIAILYYLKI
HHHHHHCCCCCCCHHHHHHHHHCCHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTIFIKVLGGIFQKALGISKVESFAAVTTIFIGQNELPAALRPFLLRMNKNELFTVMCSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCCHHHHHHHHH
MAAVSGSVLVGYAGLGVPMEYLLAASLMAIPGGILFARLLSPATEPSTVEVTDLEFGEQR
HHHHCCCCEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECCCCCCC
PSNIIEAAANGAMMGLKIAAGVGTVIMVFVGLLSLVNGIFGFVGGWFGYSGLSLDAIFGY
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ILSPLAYVMGVDWNEAQLAGALLGQKLVINEFVAYLSLSPHLADHTISAHTAAIISFGLC
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GFANFSSIGVVLGAFGMVEPKLTPVLSKLAVRALLAATLSNLMSATIAGICLGFSM
HCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFEYRGLIGIFILLLIGYIFSNNRRIIKVRTILPALGLQFLLGIIILYVPMGKYLFEQLA
CCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
SGVNHVIGYADAGSAFLFGALVGDQMNTVFHGGGFIFALKVLPTIIFVTALIAILYYLKI
HHHHHHCCCCCCCHHHHHHHHHCCHHHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTIFIKVLGGIFQKALGISKVESFAAVTTIFIGQNELPAALRPFLLRMNKNELFTVMCSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHCCCCHHHHHHHHH
MAAVSGSVLVGYAGLGVPMEYLLAASLMAIPGGILFARLLSPATEPSTVEVTDLEFGEQR
HHHHCCCCEEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECCCCCCC
PSNIIEAAANGAMMGLKIAAGVGTVIMVFVGLLSLVNGIFGFVGGWFGYSGLSLDAIFGY
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
ILSPLAYVMGVDWNEAQLAGALLGQKLVINEFVAYLSLSPHLADHTISAHTAAIISFGLC
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
GFANFSSIGVVLGAFGMVEPKLTPVLSKLAVRALLAATLSNLMSATIAGICLGFSM
HCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]