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The map label for this gene is queD [H]

Identifier: 50085444

GI number: 50085444

Start: 2314433

End: 2315029

Strand: Reverse

Name: queD [H]

Synonym: ACIAD2353

Alternate gene names: 50085444

Gene position: 2315029-2314433 (Counterclockwise)

Preceding gene: 50085445

Following gene: 50085443

Centisome position: 64.33

GC content: 39.7

Gene sequence:

>597_bases
ATGTTAATTCGTAAGTTATTTAAGTTTGAAAACGCCCATATCGTGCGAAATTGCACGTCAGACCGCTGTAAGCGTTCAAT
CCATGGTCATAGCTACAAGGTTGAGTTATTGCTTAAAGCCAATAGGCTCGATCATGGCCAAATGGTGTATGACTTCGGTT
TGCTTAAGGGGGTCATTAAGGAACTCTTTGATAGCTTTGATCATGCAATTTGTTTCTGGCAAGACGACAACCCAGAGTAT
ATTCAGGCATGTAAAACATTTAGTGCGCGCTGGATTTCGTTACCTGTTTCACCATCGGCTGAACAATTTTCTCGAATTTT
CTTTTTTTTAGCGCAGCAGGTTCTTCATTCGACCATTACCCAAAATGGGGAAGGAGATGTCGAGGTTTACTCTGTAATTG
TCCATGAGACAGACACTGGTTATGCCCAAAGCTTTTTAGAAGATATTCAAAATGTGCAAATGGGTACACTGGATTTAAAA
GACATTATCTTCTCTGATCAGGTTCAATTGGAATGGACAGATTCCCAAATGTATGAGAAGTTAAGACAAGGAGATAAGTT
CTCCAATCCGCAAGTGGAATTGCAAGTTCATATTTAA

Upstream 100 bases:

>100_bases
ATAAGACGATTCGCTAATTGTCAGTAACGTTAAAATAAATGTAAAGCCAACAGAATTGTTTTATAATACTCGATCTTGTT
ATCCATTCCTGATCGGACGC

Downstream 100 bases:

>100_bases
TCTATGATTTTAATATATTATTAAGATAGGCCAAAAGCGTTTAGGATGAAAAAATGCAGTTGACTGAGCAACAACACGAT
AAACTCAGTAAAGTTCAATT

Product: 6-pyruvoyl-tetrahydropterin synthase

Products: NA

Alternate protein names: CPH4 synthase; Queuosine biosynthesis protein queD [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MLIRKLFKFENAHIVRNCTSDRCKRSIHGHSYKVELLLKANRLDHGQMVYDFGLLKGVIKELFDSFDHAICFWQDDNPEY
IQACKTFSARWISLPVSPSAEQFSRIFFFLAQQVLHSTITQNGEGDVEVYSVIVHETDTGYAQSFLEDIQNVQMGTLDLK
DIIFSDQVQLEWTDSQMYEKLRQGDKFSNPQVELQVHI

Sequences:

>Translated_198_residues
MLIRKLFKFENAHIVRNCTSDRCKRSIHGHSYKVELLLKANRLDHGQMVYDFGLLKGVIKELFDSFDHAICFWQDDNPEY
IQACKTFSARWISLPVSPSAEQFSRIFFFLAQQVLHSTITQNGEGDVEVYSVIVHETDTGYAQSFLEDIQNVQMGTLDLK
DIIFSDQVQLEWTDSQMYEKLRQGDKFSNPQVELQVHI
>Mature_198_residues
MLIRKLFKFENAHIVRNCTSDRCKRSIHGHSYKVELLLKANRLDHGQMVYDFGLLKGVIKELFDSFDHAICFWQDDNPEY
IQACKTFSARWISLPVSPSAEQFSRIFFFLAQQVLHSTITQNGEGDVEVYSVIVHETDTGYAQSFLEDIQNVQMGTLDLK
DIIFSDQVQLEWTDSQMYEKLRQGDKFSNPQVELQVHI

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: NA

Molecular weight: Translated: 23029; Mature: 23029

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIRKLFKFENAHIVRNCTSDRCKRSIHGHSYKVELLLKANRLDHGQMVYDFGLLKGVIK
CHHHHHHHHCCCHHHHCCCHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHH
ELFDSFDHAICFWQDDNPEYIQACKTFSARWISLPVSPSAEQFSRIFFFLAQQVLHSTIT
HHHHHHCCEEEEEECCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
QNGEGDVEVYSVIVHETDTGYAQSFLEDIQNVQMGTLDLKDIIFSDQVQLEWTDSQMYEK
CCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECHHHHHHH
LRQGDKFSNPQVELQVHI
HHCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MLIRKLFKFENAHIVRNCTSDRCKRSIHGHSYKVELLLKANRLDHGQMVYDFGLLKGVIK
CHHHHHHHHCCCHHHHCCCHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHH
ELFDSFDHAICFWQDDNPEYIQACKTFSARWISLPVSPSAEQFSRIFFFLAQQVLHSTIT
HHHHHHCCEEEEEECCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
QNGEGDVEVYSVIVHETDTGYAQSFLEDIQNVQMGTLDLKDIIFSDQVQLEWTDSQMYEK
CCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECHHHHHHH
LRQGDKFSNPQVELQVHI
HHCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]