Click here to switch to the map view.

The map label for this gene is vqsM [H]

Identifier: 50085429

GI number: 50085429

Start: 2302032

End: 2303042

Strand: Reverse

Name: vqsM [H]

Synonym: ACIAD2338

Alternate gene names: 50085429

Gene position: 2303042-2302032 (Counterclockwise)

Preceding gene: 50085432

Following gene: 50085428

Centisome position: 64.0

GC content: 36.5

Gene sequence:

>1011_bases
ATGAAACGATCAATACTTGGACTGATGTATCTGATACAAGGTATGCGTAATGCAGGTATTGATGTAGATGATCGCTTAGC
ATCTATTGGTATACGACTTGATGCTCTAGATCCAAGTTCAATTATTCACGATAGTCTTGAATGGGATATCCAGTATATTA
TTGGGAAAGATGTTGATCCAGAAAAAGGACTATTTATTGGGCAACATTATGCACTTGCTGGTTATGGTCCGTTGCTCATG
CTGCTGGTGACCAGTGATAGTATTCAGACTGCAATTTATAAAGGGATCAAATATCAGAAACTTACGCATTTATCAGGTGA
GTTAGATTTACACACCACACCATCAAAAACAAATTTAGTTTATCGACCTGTCGATCTACAGTCTTCAATTGGATTGTTAC
GAGCACAATGTGAAGTTTCTGGAACATATAAATTTATTCAAGACATCTATAAAATGATGGGTTTAATTGCACCTGAGATT
AGGGTGGAATTGCCATTTGAAATGCCAAAACAGGAAGATGTTTTACAGCAATATTATCAATACTATGGACAGAATCTCCA
TTTTGGTAATAACGTAGCAACGTTTAGTCTAAATGTAGATCTACTTGATGTTAAGATTCCATCTTCAGATATTATTACGC
ATCGAGTATACGAAGCGAAATGTCAATTGGAAGTTGATCGCTTAAATGCAGAAGACATCAAAATGCCTATTATTGTGCAA
CAGGTACGTGATTATCTTGAATTGCAACAGGGTGTAATGCCAACAATGGCAGAAACAGCATATGCCTTAAATATTCCTGA
GCGCACGTTAAGACATCAGCTACAGCAGTTTGACACCAGTTATAAGAAAATTCGTGAACAACTTATTAAACACAAGGCAT
TAGAATTAATGGAATACAAAGAATATTCGATAGAAATGATTGCAGAGTTACTCGGTTATTCTGAACCAGCAGCTTTCAAT
CATGCTTTTAAACGATGGTTTGGCCAGAGTCCTAGACAGTATGGCCGATAA

Upstream 100 bases:

>100_bases
ATAATATGATTGCAATGCCGTGAAAATTGATAGAATCGGCAATTAAAATTATTTTATATTTATAGTACAACATATTGGTA
ATGTTAATATAGTTGAAATA

Downstream 100 bases:

>100_bases
AAATTACTCTTGGTATGCATCCAAAGTTCTATATGTATAGAACCAATATCCAATATACTTTTAACAGACCCAGATAGCAT
TAGAAAGATATGTCAAATAC

Product: transcriptional regulator

Products: NA

Alternate protein names: Virulence and quorum sensing modulator protein [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKRSILGLMYLIQGMRNAGIDVDDRLASIGIRLDALDPSSIIHDSLEWDIQYIIGKDVDPEKGLFIGQHYALAGYGPLLM
LLVTSDSIQTAIYKGIKYQKLTHLSGELDLHTTPSKTNLVYRPVDLQSSIGLLRAQCEVSGTYKFIQDIYKMMGLIAPEI
RVELPFEMPKQEDVLQQYYQYYGQNLHFGNNVATFSLNVDLLDVKIPSSDIITHRVYEAKCQLEVDRLNAEDIKMPIIVQ
QVRDYLELQQGVMPTMAETAYALNIPERTLRHQLQQFDTSYKKIREQLIKHKALELMEYKEYSIEMIAELLGYSEPAAFN
HAFKRWFGQSPRQYGR

Sequences:

>Translated_336_residues
MKRSILGLMYLIQGMRNAGIDVDDRLASIGIRLDALDPSSIIHDSLEWDIQYIIGKDVDPEKGLFIGQHYALAGYGPLLM
LLVTSDSIQTAIYKGIKYQKLTHLSGELDLHTTPSKTNLVYRPVDLQSSIGLLRAQCEVSGTYKFIQDIYKMMGLIAPEI
RVELPFEMPKQEDVLQQYYQYYGQNLHFGNNVATFSLNVDLLDVKIPSSDIITHRVYEAKCQLEVDRLNAEDIKMPIIVQ
QVRDYLELQQGVMPTMAETAYALNIPERTLRHQLQQFDTSYKKIREQLIKHKALELMEYKEYSIEMIAELLGYSEPAAFN
HAFKRWFGQSPRQYGR
>Mature_336_residues
MKRSILGLMYLIQGMRNAGIDVDDRLASIGIRLDALDPSSIIHDSLEWDIQYIIGKDVDPEKGLFIGQHYALAGYGPLLM
LLVTSDSIQTAIYKGIKYQKLTHLSGELDLHTTPSKTNLVYRPVDLQSSIGLLRAQCEVSGTYKFIQDIYKMMGLIAPEI
RVELPFEMPKQEDVLQQYYQYYGQNLHFGNNVATFSLNVDLLDVKIPSSDIITHRVYEAKCQLEVDRLNAEDIKMPIIVQ
QVRDYLELQQGVMPTMAETAYALNIPERTLRHQLQQFDTSYKKIREQLIKHKALELMEYKEYSIEMIAELLGYSEPAAFN
HAFKRWFGQSPRQYGR

Specific function: Transcriptional regulator involved in both the repression (at least 99 genes, such as mexR and algU) and in the activation (at least 203 genes, such as mvfR, rsaL, vqsR and rpoS) of regulatory or putative regulatory proteins which are implicated in quorum

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 38649; Mature: 38649

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSILGLMYLIQGMRNAGIDVDDRLASIGIRLDALDPSSIIHDSLEWDIQYIIGKDVDP
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHCEEEECCCHHHHHHHCHHEEEEEEECCCCCC
EKGLFIGQHYALAGYGPLLMLLVTSDSIQTAIYKGIKYQKLTHLSGELDLHTTPSKTNLV
CCCEEEECCEEECCCCCEEEEEEECCHHHHHHHHCCCHHHHHHCCCCEEEEECCCCCCEE
YRPVDLQSSIGLLRAQCEVSGTYKFIQDIYKMMGLIAPEIRVELPFEMPKQEDVLQQYYQ
EECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
YYGQNLHFGNNVATFSLNVDLLDVKIPSSDIITHRVYEAKCQLEVDRLNAEDIKMPIIVQ
HHCCCEECCCCEEEEEEEEEEEEEECCCCHHHHHHHHHHEEEEEEECCCCCCCCCHHHHH
QVRDYLELQQGVMPTMAETAYALNIPERTLRHQLQQFDTSYKKIREQLIKHKALELMEYK
HHHHHHHHHHCCCCHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYSIEMIAELLGYSEPAAFNHAFKRWFGQSPRQYGR
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHCC
>Mature Secondary Structure
MKRSILGLMYLIQGMRNAGIDVDDRLASIGIRLDALDPSSIIHDSLEWDIQYIIGKDVDP
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHCEEEECCCHHHHHHHCHHEEEEEEECCCCCC
EKGLFIGQHYALAGYGPLLMLLVTSDSIQTAIYKGIKYQKLTHLSGELDLHTTPSKTNLV
CCCEEEECCEEECCCCCEEEEEEECCHHHHHHHHCCCHHHHHHCCCCEEEEECCCCCCEE
YRPVDLQSSIGLLRAQCEVSGTYKFIQDIYKMMGLIAPEIRVELPFEMPKQEDVLQQYYQ
EECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
YYGQNLHFGNNVATFSLNVDLLDVKIPSSDIITHRVYEAKCQLEVDRLNAEDIKMPIIVQ
HHCCCEECCCCEEEEEEEEEEEEEECCCCHHHHHHHHHHEEEEEEECCCCCCCCCHHHHH
QVRDYLELQQGVMPTMAETAYALNIPERTLRHQLQQFDTSYKKIREQLIKHKALELMEYK
HHHHHHHHHHCCCCHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EYSIEMIAELLGYSEPAAFNHAFKRWFGQSPRQYGR
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]