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The map label for this gene is xcpR [H]

Identifier: 50085346

GI number: 50085346

Start: 2211164

End: 2212921

Strand: Reverse

Name: xcpR [H]

Synonym: ACIAD2241

Alternate gene names: 50085346

Gene position: 2212921-2211164 (Counterclockwise)

Preceding gene: 50085348

Following gene: 50085345

Centisome position: 61.49

GC content: 41.41

Gene sequence:

>1758_bases
ATGACATATCATTTTGAAATAGATACACAATGGTGTTTAGAACAATTATTAAAAGATGGTCGAATCAGCGAGCGCGATAA
ACTGCTTATACAAACCACACATCGAAATAAAGAACAGCTAAAATGGCATCCATTACAGTGGATTGCTCACTTTGATTTAA
AAGATCAGGCTCATACATCCAAACCATTCGATATTCTGAGATTGAGTCAGTGGCTGGCAGAGAAGGTTGGACTACCTCTA
TATGTGATCGATCCCTTGAAGGCCGATGTCAATATGCTGACCTCGGTGATGTCACAGGAATTTGCACTACGCAATAAAAT
TCTGGCTGTAGATGTCAATCCTGAGCGTATTCTGATTGGAACTGATCAGCCTTTTGTTCGAGACTGGGTGAGTAATCTTG
AGCTGAGTTTGGCACCAAAGAAAATTGAGCTTGTACTGTTATCTCCAGATCAGCTTCAGCGTTATTTACCTGAATATTAT
CAAGTGAGTCGGGCAGTACATTCTTCTAAAAATGCCACTGCTTACGAGCGAGACAATAAAGGTGTCGAGGCTTTACTTCA
ATTGGGTGATAACCAGAACCCCGATGCTAATGATCAGCATATCGTTAAACTGGTCGACTGGATTTTACAATTCGCTTTTG
AACAGGGTGCAAGTGATATTCATCTGGAACCACGTAAGGAAAAGGGAAAGGTGCGCTTTCGGATTGATGGAGTATTGCAC
ACTATTTATCATATGCCAGCCAATACCTTATCTGCTGTGATTGCACGGATTAAAATTTTAGGGCGTTTAAACGTCGCAGA
AAAAAGAAAACCTCAAGATGGTCGTTTAAAGACCCGAACGCCCAAAGGGCAAGAAACCGAACTCCGGCTTTCAACGTTAC
CTACAGCATTTGGTGAAAAACTGGTCATGCGTATTTTTGATCCAGATGTTTTAGTCAGAAGTTTTGAGCAACTCGGTTTC
GATGAAATTTTGCTTAAACAGTGGCAAGCATTGAGCCGGAATAGTCACGGCATTATTTTGGTCACGGGTCCTACTGGTTC
AGGTAAAACGACGACGTTATATTCATCGTTAAAACAATTAGCCACTGATCAGGTCAATGTTTGTACGATTGAAGATCCGA
TTGAAATGCTGGAATCAAGTTTCAATCAAATGCAGGTTAATGCTGCTATTGATCTCGGTTTTGCAGATGGAGTAAGAGCG
TTAATGCGGCAGGATCCGGATATCATTATGGTGGGTGAGATTCGTGATCAGGATACCGCCAATATGGCGATTCAGGCTGC
ACTTACGGGACATTTAGTCTTATCGACTTTACATACCAATGATGCGCCTTCTAGTTTGACCCGTTTACATGATCTGGGTG
TGCAACCCTTTTTGACAGCAGCAACTTTATTAGGTGTTTTAGCGCAACGTCTGGTGCGTCAATTATGTCCTCATTGCAAA
GTCCTTTCAGATATTGATAAACAACAATGGCAGCATCTGACACAGGATTATGAGATTGCAATGCCTGAACAAATCTATGG
GCCAGTTGGATGTGATCATTGTCGTCAAACTGGTTATAAGGGGCGTATAGGCATTTATGAGTTTATGTCCCTTGATCTAA
ATTTAAAGCAACTGGTGAGTTCTGAAGCAAATTTAAATCAATTGAAATCAGAAGCCAAAAAGCAAGGAATCCAACCTTTA
AGAATCGCAGGAGCCCGAAAAATTCTTGAGGGTGTGACTAGCCTTGAAGAAGTCTTAAGGGTGGTCCCATTAACTTAG

Upstream 100 bases:

>100_bases
ACAATTTTATCTGACTGGCTATCACTCTTTATTTTTAATGACTAAAAAATACATCATAAATGAACTCTGATATAGTGTGA
ATGGTGTGGGGGAGAAATAA

Downstream 100 bases:

>100_bases
TAAAAGGTTAGTTTAGATCTTAAGATTCACCTCATGTGTTTTTGTTGTAATTCTCTTATCAAATACAATGTTCGATCAGA
GAGGAACAGCAATGAGACGT

Product: secretion pathway ATPase

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 585; Mature: 584

Protein sequence:

>585_residues
MTYHFEIDTQWCLEQLLKDGRISERDKLLIQTTHRNKEQLKWHPLQWIAHFDLKDQAHTSKPFDILRLSQWLAEKVGLPL
YVIDPLKADVNMLTSVMSQEFALRNKILAVDVNPERILIGTDQPFVRDWVSNLELSLAPKKIELVLLSPDQLQRYLPEYY
QVSRAVHSSKNATAYERDNKGVEALLQLGDNQNPDANDQHIVKLVDWILQFAFEQGASDIHLEPRKEKGKVRFRIDGVLH
TIYHMPANTLSAVIARIKILGRLNVAEKRKPQDGRLKTRTPKGQETELRLSTLPTAFGEKLVMRIFDPDVLVRSFEQLGF
DEILLKQWQALSRNSHGIILVTGPTGSGKTTTLYSSLKQLATDQVNVCTIEDPIEMLESSFNQMQVNAAIDLGFADGVRA
LMRQDPDIIMVGEIRDQDTANMAIQAALTGHLVLSTLHTNDAPSSLTRLHDLGVQPFLTAATLLGVLAQRLVRQLCPHCK
VLSDIDKQQWQHLTQDYEIAMPEQIYGPVGCDHCRQTGYKGRIGIYEFMSLDLNLKQLVSSEANLNQLKSEAKKQGIQPL
RIAGARKILEGVTSLEEVLRVVPLT

Sequences:

>Translated_585_residues
MTYHFEIDTQWCLEQLLKDGRISERDKLLIQTTHRNKEQLKWHPLQWIAHFDLKDQAHTSKPFDILRLSQWLAEKVGLPL
YVIDPLKADVNMLTSVMSQEFALRNKILAVDVNPERILIGTDQPFVRDWVSNLELSLAPKKIELVLLSPDQLQRYLPEYY
QVSRAVHSSKNATAYERDNKGVEALLQLGDNQNPDANDQHIVKLVDWILQFAFEQGASDIHLEPRKEKGKVRFRIDGVLH
TIYHMPANTLSAVIARIKILGRLNVAEKRKPQDGRLKTRTPKGQETELRLSTLPTAFGEKLVMRIFDPDVLVRSFEQLGF
DEILLKQWQALSRNSHGIILVTGPTGSGKTTTLYSSLKQLATDQVNVCTIEDPIEMLESSFNQMQVNAAIDLGFADGVRA
LMRQDPDIIMVGEIRDQDTANMAIQAALTGHLVLSTLHTNDAPSSLTRLHDLGVQPFLTAATLLGVLAQRLVRQLCPHCK
VLSDIDKQQWQHLTQDYEIAMPEQIYGPVGCDHCRQTGYKGRIGIYEFMSLDLNLKQLVSSEANLNQLKSEAKKQGIQPL
RIAGARKILEGVTSLEEVLRVVPLT
>Mature_584_residues
TYHFEIDTQWCLEQLLKDGRISERDKLLIQTTHRNKEQLKWHPLQWIAHFDLKDQAHTSKPFDILRLSQWLAEKVGLPLY
VIDPLKADVNMLTSVMSQEFALRNKILAVDVNPERILIGTDQPFVRDWVSNLELSLAPKKIELVLLSPDQLQRYLPEYYQ
VSRAVHSSKNATAYERDNKGVEALLQLGDNQNPDANDQHIVKLVDWILQFAFEQGASDIHLEPRKEKGKVRFRIDGVLHT
IYHMPANTLSAVIARIKILGRLNVAEKRKPQDGRLKTRTPKGQETELRLSTLPTAFGEKLVMRIFDPDVLVRSFEQLGFD
EILLKQWQALSRNSHGIILVTGPTGSGKTTTLYSSLKQLATDQVNVCTIEDPIEMLESSFNQMQVNAAIDLGFADGVRAL
MRQDPDIIMVGEIRDQDTANMAIQAALTGHLVLSTLHTNDAPSSLTRLHDLGVQPFLTAATLLGVLAQRLVRQLCPHCKV
LSDIDKQQWQHLTQDYEIAMPEQIYGPVGCDHCRQTGYKGRIGIYEFMSLDLNLKQLVSSEANLNQLKSEAKKQGIQPLR
IAGARKILEGVTSLEEVLRVVPLT

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins. Required for the translocation of a variety of enzymes across the outer membrane [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=386, Percent_Identity=45.3367875647668, Blast_Score=339, Evalue=3e-94,
Organism=Escherichia coli, GI1786296, Length=387, Percent_Identity=40.3100775193798, Blast_Score=293, Evalue=3e-80,
Organism=Escherichia coli, GI87082188, Length=224, Percent_Identity=35.2678571428571, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 66194; Mature: 66063

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYHFEIDTQWCLEQLLKDGRISERDKLLIQTTHRNKEQLKWHPLQWIAHFDLKDQAHTS
CEEEEECCHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHCCCCHHHHHEECCCCCCCCCC
KPFDILRLSQWLAEKVGLPLYVIDPLKADVNMLTSVMSQEFALRNKILAVDVNPERILIG
CCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEE
TDQPFVRDWVSNLELSLAPKKIELVLLSPDQLQRYLPEYYQVSRAVHSSKNATAYERDNK
CCCHHHHHHHHCCEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
GVEALLQLGDNQNPDANDQHIVKLVDWILQFAFEQGASDIHLEPRKEKGKVRFRIDGVLH
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEHHHHH
TIYHMPANTLSAVIARIKILGRLNVAEKRKPQDGRLKTRTPKGQETELRLSTLPTAFGEK
HHHHCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCEEEHHHCCHHHHHH
LVMRIFDPDVLVRSFEQLGFDEILLKQWQALSRNSHGIILVTGPTGSGKTTTLYSSLKQL
HHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHH
ATDQVNVCTIEDPIEMLESSFNQMQVNAAIDLGFADGVRALMRQDPDIIMVGEIRDQDTA
HCCCCEEEEEHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHHHCCCCEEEEECCCCCCHH
NMAIQAALTGHLVLSTLHTNDAPSSLTRLHDLGVQPFLTAATLLGVLAQRLVRQLCPHCK
HHHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
VLSDIDKQQWQHLTQDYEIAMPEQIYGPVGCDHCRQTGYKGRIGIYEFMSLDLNLKQLVS
HHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHCCCCCCCCHHHHHCCCCCHHHHHC
SEANLNQLKSEAKKQGIQPLRIAGARKILEGVTSLEEVLRVVPLT
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TYHFEIDTQWCLEQLLKDGRISERDKLLIQTTHRNKEQLKWHPLQWIAHFDLKDQAHTS
EEEEECCHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHCCCCHHHHHEECCCCCCCCCC
KPFDILRLSQWLAEKVGLPLYVIDPLKADVNMLTSVMSQEFALRNKILAVDVNPERILIG
CCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEE
TDQPFVRDWVSNLELSLAPKKIELVLLSPDQLQRYLPEYYQVSRAVHSSKNATAYERDNK
CCCHHHHHHHHCCEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
GVEALLQLGDNQNPDANDQHIVKLVDWILQFAFEQGASDIHLEPRKEKGKVRFRIDGVLH
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEHHHHH
TIYHMPANTLSAVIARIKILGRLNVAEKRKPQDGRLKTRTPKGQETELRLSTLPTAFGEK
HHHHCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCEEEHHHCCHHHHHH
LVMRIFDPDVLVRSFEQLGFDEILLKQWQALSRNSHGIILVTGPTGSGKTTTLYSSLKQL
HHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHH
ATDQVNVCTIEDPIEMLESSFNQMQVNAAIDLGFADGVRALMRQDPDIIMVGEIRDQDTA
HCCCCEEEEEHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHHHCCCCEEEEECCCCCCHH
NMAIQAALTGHLVLSTLHTNDAPSSLTRLHDLGVQPFLTAATLLGVLAQRLVRQLCPHCK
HHHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHH
VLSDIDKQQWQHLTQDYEIAMPEQIYGPVGCDHCRQTGYKGRIGIYEFMSLDLNLKQLVS
HHHHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHCCCCCCCCHHHHHCCCCCHHHHHC
SEANLNQLKSEAKKQGIQPLRIAGARKILEGVTSLEEVLRVVPLT
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1588814; 10984043 [H]