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The map label for this gene is mmgC [H]

Identifier: 50084966

GI number: 50084966

Start: 1826187

End: 1827290

Strand: Direct

Name: mmgC [H]

Synonym: ACIAD1819

Alternate gene names: 50084966

Gene position: 1826187-1827290 (Clockwise)

Preceding gene: 50084965

Following gene: 50084967

Centisome position: 50.75

GC content: 47.83

Gene sequence:

>1104_bases
ATGTCAAAGTTAATGATTGAAGATAGCGACGGCGTATTGGGTATGTTGCAAGAGAGTGTCCATAGCTTCGCACAGCAATT
TCCCGGCCCTAAAGGTTTAAGACAAATTCGAGAGGCGAATGGGGCTGCGAATCGTCGACAGTGGCAAGCCATGGTAGATG
CTGGATGGATTGGGTTGTTATTACCTGAAGCGATGGGCGGTGCTGGTTTAAGTTTGCGTGAACAGGTCGTGATCAGTCAT
GCATTAGGCGAGGCCTTGATCGTTTCGCCTATGGTCACTGCATCGGTTCAAAGCAGTTCAATCTTGGCACAGCTCGTACC
GAGTCAAGAGCGTGATCGGTTGGTGTCAGGATTAATCGATGGCACGGTGTGTGTCGTCTCGAGTGTGAACAGCATACTGA
AGCTGACGACTCAGGCGAATGCGCTGGTTTTAAATGGTGTATGTGAACACCTAGAGGCAGCAGGCTTAGTGACTGACTAT
CTGCTTTTGGCGCATGATCATACGCAGCAGTATCTGCTCAGTATTCCCGCAGAGCGTGTTGCTCAAATGAAACGTGATCG
CCCTGCTGTAGATGGTACTTGTTTATCTGCGCTACATTTTGAACACTTCAATATTGTCGCTGAACAGATTTTAGCGGCAG
GAGATCTGAATCTAATTGCTCAGAATGCGCTCAATGCTGCACGGTTAGCAGTGTCAGCAGAACTGGCTGGATTGGCCAGC
GGTGCATTTTCAATGACCAGTGAATATACCCAACAACGAGTTCAATTTGGCAAACCGATTGCCAGCTTTCAAGCGATTCA
ACATCGTTTAGTCGATATGTGGACCAAGGCTGAATTTGCATGTGCAAGCATTGACAACGCGATTGAATGCTTAAATTTAG
AAGACAAGACCAAAGCCCATATGGCGATTCTGGCCGCCAAAATTCGTTGTAGTGATGCAGCCACCATAATTGCTCGCCAA
GCCGTCCATTTATTTGGTGCTATGGGATTTACCGACGAATGCGACATTGGTTTATATCTCAAACGTGCAGTCAATCTGGC
GGCCTCGCTGGGCGATGCAGAAAGCTTAAGACTTCAGTTTATCGAAATGGAACGTGCCGCCTAG

Upstream 100 bases:

>100_bases
CGGCGACCGGAAAATTACAAAAAAATGTGTTACGCGAACAGTTTAAGGATTTTGTCTTCAGTTCAGACCGATCATGAAGA
CGTATTAAAGGAAGCGAATA

Downstream 100 bases:

>100_bases
GCGCTGCAATAAAGGAATACAATATGCTAAATCAATTAATTAAAACCGAAATCTCTCAGCATGTGGCGGTGGTTACGCTC
AATAATCCACCCGTCAATGC

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSKLMIEDSDGVLGMLQESVHSFAQQFPGPKGLRQIREANGAANRRQWQAMVDAGWIGLLLPEAMGGAGLSLREQVVISH
ALGEALIVSPMVTASVQSSSILAQLVPSQERDRLVSGLIDGTVCVVSSVNSILKLTTQANALVLNGVCEHLEAAGLVTDY
LLLAHDHTQQYLLSIPAERVAQMKRDRPAVDGTCLSALHFEHFNIVAEQILAAGDLNLIAQNALNAARLAVSAELAGLAS
GAFSMTSEYTQQRVQFGKPIASFQAIQHRLVDMWTKAEFACASIDNAIECLNLEDKTKAHMAILAAKIRCSDAATIIARQ
AVHLFGAMGFTDECDIGLYLKRAVNLAASLGDAESLRLQFIEMERAA

Sequences:

>Translated_367_residues
MSKLMIEDSDGVLGMLQESVHSFAQQFPGPKGLRQIREANGAANRRQWQAMVDAGWIGLLLPEAMGGAGLSLREQVVISH
ALGEALIVSPMVTASVQSSSILAQLVPSQERDRLVSGLIDGTVCVVSSVNSILKLTTQANALVLNGVCEHLEAAGLVTDY
LLLAHDHTQQYLLSIPAERVAQMKRDRPAVDGTCLSALHFEHFNIVAEQILAAGDLNLIAQNALNAARLAVSAELAGLAS
GAFSMTSEYTQQRVQFGKPIASFQAIQHRLVDMWTKAEFACASIDNAIECLNLEDKTKAHMAILAAKIRCSDAATIIARQ
AVHLFGAMGFTDECDIGLYLKRAVNLAASLGDAESLRLQFIEMERAA
>Mature_366_residues
SKLMIEDSDGVLGMLQESVHSFAQQFPGPKGLRQIREANGAANRRQWQAMVDAGWIGLLLPEAMGGAGLSLREQVVISHA
LGEALIVSPMVTASVQSSSILAQLVPSQERDRLVSGLIDGTVCVVSSVNSILKLTTQANALVLNGVCEHLEAAGLVTDYL
LLAHDHTQQYLLSIPAERVAQMKRDRPAVDGTCLSALHFEHFNIVAEQILAAGDLNLIAQNALNAARLAVSAELAGLASG
AFSMTSEYTQQRVQFGKPIASFQAIQHRLVDMWTKAEFACASIDNAIECLNLEDKTKAHMAILAAKIRCSDAATIIARQA
VHLFGAMGFTDECDIGLYLKRAVNLAASLGDAESLRLQFIEMERAA

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=24.7340425531915, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4557233, Length=306, Percent_Identity=26.797385620915, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI21361497, Length=336, Percent_Identity=24.702380952381, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17506239, Length=312, Percent_Identity=26.2820512820513, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=314, Percent_Identity=25.796178343949, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=370, Percent_Identity=24.0540540540541, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71985184, Length=313, Percent_Identity=23.0031948881789, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646207, Length=361, Percent_Identity=25.7617728531856, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21356377, Length=342, Percent_Identity=24.5614035087719, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 39417; Mature: 39286

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLMIEDSDGVLGMLQESVHSFAQQFPGPKGLRQIREANGAANRRQWQAMVDAGWIGLL
CCCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
LPEAMGGAGLSLREQVVISHALGEALIVSPMVTASVQSSSILAQLVPSQERDRLVSGLID
HHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHH
GTVCVVSSVNSILKLTTQANALVLNGVCEHLEAAGLVTDYLLLAHDHTQQYLLSIPAERV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHH
AQMKRDRPAVDGTCLSALHFEHFNIVAEQILAAGDLNLIAQNALNAARLAVSAELAGLAS
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GAFSMTSEYTQQRVQFGKPIASFQAIQHRLVDMWTKAEFACASIDNAIECLNLEDKTKAH
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
MAILAAKIRCSDAATIIARQAVHLFGAMGFTDECDIGLYLKRAVNLAASLGDAESLRLQF
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
IEMERAA
HHHHCCC
>Mature Secondary Structure 
SKLMIEDSDGVLGMLQESVHSFAQQFPGPKGLRQIREANGAANRRQWQAMVDAGWIGLL
CCEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
LPEAMGGAGLSLREQVVISHALGEALIVSPMVTASVQSSSILAQLVPSQERDRLVSGLID
HHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHH
GTVCVVSSVNSILKLTTQANALVLNGVCEHLEAAGLVTDYLLLAHDHTQQYLLSIPAERV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHH
AQMKRDRPAVDGTCLSALHFEHFNIVAEQILAAGDLNLIAQNALNAARLAVSAELAGLAS
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GAFSMTSEYTQQRVQFGKPIASFQAIQHRLVDMWTKAEFACASIDNAIECLNLEDKTKAH
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
MAILAAKIRCSDAATIIARQAVHLFGAMGFTDECDIGLYLKRAVNLAASLGDAESLRLQF
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
IEMERAA
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]