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The map label for this gene is qorA [H]

Identifier: 50084895

GI number: 50084895

Start: 1751010

End: 1752011

Strand: Reverse

Name: qorA [H]

Synonym: ACIAD1743

Alternate gene names: 50084895

Gene position: 1752011-1751010 (Counterclockwise)

Preceding gene: 50084896

Following gene: 50084894

Centisome position: 48.69

GC content: 39.22

Gene sequence:

>1002_bases
ATGACGGATTTGCCCACAACAATGCGACATATCGAAATTTCTCAATCTGGCGATCCAGATGTTTTACATATTGTAGAAAC
CTCTTTACCAAAAATAAAAATTGATGAAATCCTCATTGAAGTAAAAGCATTTGGTATCAACCGACCAGATGTTCTACAAC
GCAAAGGACTTTATCCAATGCCTAAGGATGTGACTCCAATTCCTGGTCTTGAAGTTGCTGGAATTGTCACTGCTATAGGC
GAGAATGTTAGCCAGTTTAAAGTTGGTGATCGAGTTTGTGCATTGACCAATGGTGGTGGTTATGCAGAGTATTGTGCTGT
ACCAGAAACTCAAACCCTTCCTATTCCCTCCAATCTTTCTTATATAGAAGCAGCCGCTATACCTGAAACCTATTTCACGG
TATGGGCCAACCTGTTTGATATTGGTCAATTATCTGTTGGTGAAACCGCGCTTATTCATGGCGGAGCGAGCGGTATTGGC
ACAACAGCACTCACACTTTGCCACGCGATGGGCATCAAAACATTCTGCACAGTAGGCAGTGATGACAAAGTTGATGCTTT
AAATAAAATCACTACCGCAATCAATTATAAAAAACATAATTTTGAAGAAGTGATTTTAGAGCAGACCCAAAATAAAGGCG
TAGATGTGATTCTTGATATTGTTGGAGGTAAATATTTCCAACAAAACATGAACACATTAAAGCGAGATGGTCGACTTGTA
ATCCTTGGATTTATGGGTGGACGCTATGCGAAAGAGTTTGATCTACAACAGTTAATTTTGAAGCGAGCGAAAGTGACTGG
TTCTACCATGCGTGCGCGGACTGATCAGGAAAAATCTGAAATTACTCAATCACTAAGACAGCATGTTTGGCCATTACTCT
CTGAAGGCAAAAGTTTACCCCTCATTTATAAATCCTTTAGCTTTGAAGATATTTCCAAAGCTCATACATGTATGGAAGAA
AGTGAGCATATTGGCAAAATAGTAATTACATTAACTGAATAA

Upstream 100 bases:

>100_bases
ATAAATAACTCAAACCATCAGATAAGCTTGGAGATGTCTAAAATATCGTATAAATACGATATATCATTTATGAAGATATA
GAAACTCAGGAAAAAACTCT

Downstream 100 bases:

>100_bases
TCAAAATGTGAAGTACAGGACTTTTCCAATTCATTAGAAAAGTCTCGTACATCTTCATTGTTACATCACTATAATTAGGT
CAACTTACAATAAATCATAG

Product: oxydoreductase protein, zinc-containing (quinone oxidoreductase, NADPH dependent)

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTDLPTTMRHIEISQSGDPDVLHIVETSLPKIKIDEILIEVKAFGINRPDVLQRKGLYPMPKDVTPIPGLEVAGIVTAIG
ENVSQFKVGDRVCALTNGGGYAEYCAVPETQTLPIPSNLSYIEAAAIPETYFTVWANLFDIGQLSVGETALIHGGASGIG
TTALTLCHAMGIKTFCTVGSDDKVDALNKITTAINYKKHNFEEVILEQTQNKGVDVILDIVGGKYFQQNMNTLKRDGRLV
ILGFMGGRYAKEFDLQQLILKRAKVTGSTMRARTDQEKSEITQSLRQHVWPLLSEGKSLPLIYKSFSFEDISKAHTCMEE
SEHIGKIVITLTE

Sequences:

>Translated_333_residues
MTDLPTTMRHIEISQSGDPDVLHIVETSLPKIKIDEILIEVKAFGINRPDVLQRKGLYPMPKDVTPIPGLEVAGIVTAIG
ENVSQFKVGDRVCALTNGGGYAEYCAVPETQTLPIPSNLSYIEAAAIPETYFTVWANLFDIGQLSVGETALIHGGASGIG
TTALTLCHAMGIKTFCTVGSDDKVDALNKITTAINYKKHNFEEVILEQTQNKGVDVILDIVGGKYFQQNMNTLKRDGRLV
ILGFMGGRYAKEFDLQQLILKRAKVTGSTMRARTDQEKSEITQSLRQHVWPLLSEGKSLPLIYKSFSFEDISKAHTCMEE
SEHIGKIVITLTE
>Mature_332_residues
TDLPTTMRHIEISQSGDPDVLHIVETSLPKIKIDEILIEVKAFGINRPDVLQRKGLYPMPKDVTPIPGLEVAGIVTAIGE
NVSQFKVGDRVCALTNGGGYAEYCAVPETQTLPIPSNLSYIEAAAIPETYFTVWANLFDIGQLSVGETALIHGGASGIGT
TALTLCHAMGIKTFCTVGSDDKVDALNKITTAINYKKHNFEEVILEQTQNKGVDVILDIVGGKYFQQNMNTLKRDGRLVI
LGFMGGRYAKEFDLQQLILKRAKVTGSTMRARTDQEKSEITQSLRQHVWPLLSEGKSLPLIYKSFSFEDISKAHTCMEES
EHIGKIVITLTE

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=332, Percent_Identity=36.144578313253, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI22538444, Length=332, Percent_Identity=36.144578313253, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=27.9635258358663, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=27.9635258358663, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI18379349, Length=309, Percent_Identity=29.7734627831715, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI24308257, Length=338, Percent_Identity=24.2603550295858, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI194239676, Length=327, Percent_Identity=25.9938837920489, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI41872631, Length=258, Percent_Identity=28.2945736434109, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI28557745, Length=324, Percent_Identity=29.0123456790123, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI47519420, Length=372, Percent_Identity=23.9247311827957, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI90669511, Length=171, Percent_Identity=32.7485380116959, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI67078404, Length=251, Percent_Identity=23.9043824701195, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI197927207, Length=198, Percent_Identity=22.7272727272727, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790485, Length=241, Percent_Identity=33.195020746888, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17507255, Length=329, Percent_Identity=25.531914893617, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17536829, Length=251, Percent_Identity=29.4820717131474, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI212642053, Length=324, Percent_Identity=25.3086419753086, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71987554, Length=242, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=337, Percent_Identity=25.5192878338279, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323961, Length=282, Percent_Identity=24.822695035461, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=282, Percent_Identity=24.468085106383, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=289, Percent_Identity=23.8754325259516, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19920632, Length=311, Percent_Identity=27.3311897106109, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI221330659, Length=311, Percent_Identity=27.3311897106109, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24581345, Length=290, Percent_Identity=27.2413793103448, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI45550423, Length=297, Percent_Identity=25.5892255892256, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24581341, Length=367, Percent_Identity=25.0681198910082, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24581339, Length=367, Percent_Identity=25.0681198910082, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 36614; Mature: 36482

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLPTTMRHIEISQSGDPDVLHIVETSLPKIKIDEILIEVKAFGINRPDVLQRKGLYPM
CCCCCCCHHEEEECCCCCCCEEEEEECCCCCEEHHHHHEEHHHCCCCCCHHHHHCCCCCC
PKDVTPIPGLEVAGIVTAIGENVSQFKVGDRVCALTNGGGYAEYCAVPETQTLPIPSNLS
CCCCCCCCCCHHHHHHHHHCCCHHHEECCCEEEEEECCCCCEEEECCCCCCCCCCCCCCC
YIEAAAIPETYFTVWANLFDIGQLSVGETALIHGGASGIGTTALTLCHAMGIKTFCTVGS
HHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHEEECCC
DDKVDALNKITTAINYKKHNFEEVILEQTQNKGVDVILDIVGGKYFQQNMNTLKRDGRLV
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCEE
ILGFMGGRYAKEFDLQQLILKRAKVTGSTMRARTDQEKSEITQSLRQHVWPLLSEGKSLP
EEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC
LIYKSFSFEDISKAHTCMEESEHIGKIVITLTE
EEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEC
>Mature Secondary Structure 
TDLPTTMRHIEISQSGDPDVLHIVETSLPKIKIDEILIEVKAFGINRPDVLQRKGLYPM
CCCCCCHHEEEECCCCCCCEEEEEECCCCCEEHHHHHEEHHHCCCCCCHHHHHCCCCCC
PKDVTPIPGLEVAGIVTAIGENVSQFKVGDRVCALTNGGGYAEYCAVPETQTLPIPSNLS
CCCCCCCCCCHHHHHHHHHCCCHHHEECCCEEEEEECCCCCEEEECCCCCCCCCCCCCCC
YIEAAAIPETYFTVWANLFDIGQLSVGETALIHGGASGIGTTALTLCHAMGIKTFCTVGS
HHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHEEECCC
DDKVDALNKITTAINYKKHNFEEVILEQTQNKGVDVILDIVGGKYFQQNMNTLKRDGRLV
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCEE
ILGFMGGRYAKEFDLQQLILKRAKVTGSTMRARTDQEKSEITQSLRQHVWPLLSEGKSLP
EEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC
LIYKSFSFEDISKAHTCMEESEHIGKIVITLTE
EEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]