Click here to switch to the map view.

The map label for this gene is yciC [H]

Identifier: 50084893

GI number: 50084893

Start: 1748736

End: 1749944

Strand: Reverse

Name: yciC [H]

Synonym: ACIAD1741

Alternate gene names: 50084893

Gene position: 1749944-1748736 (Counterclockwise)

Preceding gene: 50084894

Following gene: 50084892

Centisome position: 48.63

GC content: 40.28

Gene sequence:

>1209_bases
ATGGTCAGTTCCGTAGCCAATCCTTCATACAAACTTCCTGTTACTGTCTTATCAGGATTTTTAGGTGCAGGAAAAACAAC
CTTGCTTAATCATATTTTAAACAATCGCGAAGGTCGCCGTGTAGCAGTGATTGTAAATGATATGTCAGAAGTCAATATTG
ATGCTGCTCTGGTTCAAAATGGTGGCGCAGAACTCTCACGTACAGATGAAAAACTCGTCGAAATGAGCAATGGTTGTATA
TGTTGTACGTTACGTGAAGATTTATTGATTGAAGTTAAACGCTTGGCAGAAGAAAACAAATTTGACCAACTGGTGATTGA
ATCGACTGGAATATCGGAACCTCTTCCTGTCGCAGAAACCTTTACTTTTGCAGATGAAGCAGGTCAATCTTTAAATGAAT
TTGCTCAACTCGATACAATGGTGACTGTGGTTGACGCATTTAATTTTCTACAAGACTATAGCTCTTATGATCAATTAAAT
GATCGTGGTGAGTCTCTTGGCGAGCACGATCAACGCAGCGTTGTAGATTTGCTTATCGATCAGATTGAGTTTTGCGATGT
AATCATCCTGAATAAAGTGGACTTGATTGATGATATTAAAAAAGAACGTTTAATGGCTATTCTGAATAAACTTAATCCAC
GGGCAAGAATTCAAATTTCAGAATTTGGAAAAGTAGATTTAGATTCAGTCTTGAATACAGGTTTATTTGATTTCGATCAA
GCTGCACAAGCCCCAGGCTGGCTAAAAGAACTTCGTGGTGAACATGTGCCAGAAACAGAAGAATACGGCATTACAAGTTT
TGTATATCGCGCTCGTCGCCCTTTTCATCCACAACGGTTTTTTAATTTTATTAATTCTGAATGGCCAGGTGTTATTCGTT
CAAAAGGTTTTTTCTGGCTAGCCTGCGAACCAACGCTCGCATGCTCTTGGTCACAAGCTGGTGGTATGGCAAGACACGGT
ATGGCAGGCACATGGTGGGCTGCAACAGAACCAGAGAACTGGCCAAGAGATGATCAGTCACTTGCCGAAATTGAAAAACA
TTGGGATGAAAAAGTTGGTGATGCTCGTCAAGAGATTGTCATGATTGGAATGGATATGAATCAAGATACACTTATTCAAG
GTTTCAATGAATGTCTACTCAGCGATGATGAAATGGCGCTTGGCCCTGACGGCTGGACTCAAATGTCAAATCCGTTTGAT
TGGTCTTAA

Upstream 100 bases:

>100_bases
TTTCGTGACGTTATCAGTTCAGCACAACTGCATATTTCAGCTTTGCTAAATAAATTGTCATCGAATTCATGATTTTTCTC
TTTTGCATAGGACATCGCCA

Downstream 100 bases:

>100_bases
TCACTAAATTTTAATTCTATTTAATCACTTATATTGTATAACCTAATATGAATGCTCAACTTCCCGATGTATCAGTCTCA
CAGCTTCCTTGCAATTTATC

Product: regulatory protein (nitrile hydratase activator like)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MVSSVANPSYKLPVTVLSGFLGAGKTTLLNHILNNREGRRVAVIVNDMSEVNIDAALVQNGGAELSRTDEKLVEMSNGCI
CCTLREDLLIEVKRLAEENKFDQLVIESTGISEPLPVAETFTFADEAGQSLNEFAQLDTMVTVVDAFNFLQDYSSYDQLN
DRGESLGEHDQRSVVDLLIDQIEFCDVIILNKVDLIDDIKKERLMAILNKLNPRARIQISEFGKVDLDSVLNTGLFDFDQ
AAQAPGWLKELRGEHVPETEEYGITSFVYRARRPFHPQRFFNFINSEWPGVIRSKGFFWLACEPTLACSWSQAGGMARHG
MAGTWWAATEPENWPRDDQSLAEIEKHWDEKVGDARQEIVMIGMDMNQDTLIQGFNECLLSDDEMALGPDGWTQMSNPFD
WS

Sequences:

>Translated_402_residues
MVSSVANPSYKLPVTVLSGFLGAGKTTLLNHILNNREGRRVAVIVNDMSEVNIDAALVQNGGAELSRTDEKLVEMSNGCI
CCTLREDLLIEVKRLAEENKFDQLVIESTGISEPLPVAETFTFADEAGQSLNEFAQLDTMVTVVDAFNFLQDYSSYDQLN
DRGESLGEHDQRSVVDLLIDQIEFCDVIILNKVDLIDDIKKERLMAILNKLNPRARIQISEFGKVDLDSVLNTGLFDFDQ
AAQAPGWLKELRGEHVPETEEYGITSFVYRARRPFHPQRFFNFINSEWPGVIRSKGFFWLACEPTLACSWSQAGGMARHG
MAGTWWAATEPENWPRDDQSLAEIEKHWDEKVGDARQEIVMIGMDMNQDTLIQGFNECLLSDDEMALGPDGWTQMSNPFD
WS
>Mature_402_residues
MVSSVANPSYKLPVTVLSGFLGAGKTTLLNHILNNREGRRVAVIVNDMSEVNIDAALVQNGGAELSRTDEKLVEMSNGCI
CCTLREDLLIEVKRLAEENKFDQLVIESTGISEPLPVAETFTFADEAGQSLNEFAQLDTMVTVVDAFNFLQDYSSYDQLN
DRGESLGEHDQRSVVDLLIDQIEFCDVIILNKVDLIDDIKKERLMAILNKLNPRARIQISEFGKVDLDSVLNTGLFDFDQ
AAQAPGWLKELRGEHVPETEEYGITSFVYRARRPFHPQRFFNFINSEWPGVIRSKGFFWLACEPTLACSWSQAGGMARHG
MAGTWWAATEPENWPRDDQSLAEIEKHWDEKVGDARQEIVMIGMDMNQDTLIQGFNECLLSDDEMALGPDGWTQMSNPFD
WS

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=291, Percent_Identity=29.8969072164948, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI146231952, Length=291, Percent_Identity=29.8969072164948, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI148727351, Length=291, Percent_Identity=29.553264604811, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI126722884, Length=291, Percent_Identity=29.553264604811, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI223941779, Length=197, Percent_Identity=34.5177664974619, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI223941776, Length=280, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI119120938, Length=138, Percent_Identity=38.4057971014493, Blast_Score=99, Evalue=6e-21,
Organism=Escherichia coli, GI87082430, Length=304, Percent_Identity=29.2763157894737, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788499, Length=212, Percent_Identity=27.3584905660377, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324356, Length=236, Percent_Identity=27.5423728813559, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 45243; Mature: 45243

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSSVANPSYKLPVTVLSGFLGAGKTTLLNHILNNREGRRVAVIVNDMSEVNIDAALVQN
CCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHCC
GGAELSRTDEKLVEMSNGCICCTLREDLLIEVKRLAEENKFDQLVIESTGISEPLPVAET
CCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCHHHH
FTFADEAGQSLNEFAQLDTMVTVVDAFNFLQDYSSYDQLNDRGESLGEHDQRSVVDLLID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
QIEFCDVIILNKVDLIDDIKKERLMAILNKLNPRARIQISEFGKVDLDSVLNTGLFDFDQ
HHHHHCCCEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCCHH
AAQAPGWLKELRGEHVPETEEYGITSFVYRARRPFHPQRFFNFINSEWPGVIRSKGFFWL
HHCCCHHHHHHCCCCCCCHHHCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCEEEE
ACEPTLACSWSQAGGMARHGMAGTWWAATEPENWPRDDQSLAEIEKHWDEKVGDARQEIV
EECCCEEECCHHCCCCHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEE
MIGMDMNQDTLIQGFNECLLSDDEMALGPDGWTQMSNPFDWS
EEECCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MVSSVANPSYKLPVTVLSGFLGAGKTTLLNHILNNREGRRVAVIVNDMSEVNIDAALVQN
CCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHCC
GGAELSRTDEKLVEMSNGCICCTLREDLLIEVKRLAEENKFDQLVIESTGISEPLPVAET
CCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCHHHH
FTFADEAGQSLNEFAQLDTMVTVVDAFNFLQDYSSYDQLNDRGESLGEHDQRSVVDLLID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
QIEFCDVIILNKVDLIDDIKKERLMAILNKLNPRARIQISEFGKVDLDSVLNTGLFDFDQ
HHHHHCCCEECCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCCHH
AAQAPGWLKELRGEHVPETEEYGITSFVYRARRPFHPQRFFNFINSEWPGVIRSKGFFWL
HHCCCHHHHHHCCCCCCCHHHCCHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCEEEE
ACEPTLACSWSQAGGMARHGMAGTWWAATEPENWPRDDQSLAEIEKHWDEKVGDARQEIV
EECCCEEECCHHCCCCHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEE
MIGMDMNQDTLIQGFNECLLSDDEMALGPDGWTQMSNPFDWS
EEECCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]