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The map label for this gene is fadH [H]

Identifier: 50084811

GI number: 50084811

Start: 1652368

End: 1654392

Strand: Direct

Name: fadH [H]

Synonym: ACIAD1654

Alternate gene names: 50084811

Gene position: 1652368-1654392 (Clockwise)

Preceding gene: 50084805

Following gene: 50084812

Centisome position: 45.92

GC content: 41.63

Gene sequence:

>2025_bases
ATGTCGTTTTATCCACATTTACTTGCACCCCTAGATTTAGGTTTTACTACTTTAAAAAATAGAATAATGATGGGATCTAT
GCATATTGGTCTTGAAGAAGCCCCAGGTGGTTATGAGCGCATGGCTGCTTTTTATGCAGAGCGTGCTAAAGGTGAGGTCG
GGCTTATTGTAACAGGGGGGATCGCACCCAATGATGCAGGTCGTACTTTTGCTCATGCCTCAAAATTAGATACCAGAGAA
GAAGCAGTAAAACATAAGATTATTACACAAGCAGTACATGATGCGGGTGGTAAAATAGCCATGCAGATTTTGCATACTGG
CCGTTATTCTTATCAACAAAATATTGTTGCACCTTCTGCTATTCAGGCTCCAATCAACCCGATAAAACCACAGGAATTAA
GCTCAGCAGAGGTGTGGCAAACTGTTTCTGATTTTGTAAATTGTGCAAAATTGGCTCAGTATGCTGGCTATGATGGTGTT
GAAATTATGGGGTCGGAAGGTTATCTCATTAATGAGTTTATTGCTGCACGTACTAACCACCGTGAGGATGAGTGGGGTGG
TCACTATGAAAATCGTATTCGTTTTCCTATTGAAATTGTAAAACGTACGCGTGCTGAAGTGGGTGAAAATTTTATTATTA
TCTATCGCCTATCGATGCTAGACCTTGTGGAAGGTGGTTCAACGCTGGATGAAGTCATTCATTTAGCGAAGGAAATTGAA
AAGGCAGGTGCCACCATTATAAATACAGGCATTGGTTGGCATGAAGCACGTATTCCTACAATTGCGACAAAGGTGCCACG
TGCAGCATTTACATGGGTTACAGAGAAAATTAGACCGCATGTTAAAACGCCACTGATCACTTCTAATCGTATTAATACAC
CAGAAATGGCAGAGCACGTCTTGGCAAATGGTCAAGCCGATCTCATTTCTATGGCACGTCCGATGCTTGCCGATCCAGAG
TTTGCATTAAAGGCAGGTGAAGGGCGTAGTGATGAAATTAACACCTGTATCGGCTGCAATCAGGCATGTCTTGATCATAT
TTTTACAGGAACTGTTGCTTCGTGTTTGGTTAATCCACGTGCATGTCACGAAACTGAATTAAAATTTCCCCAGGCTGACA
AGGTTAAACAGATTGCAGTGATTGGAGCTGGTCCAGCAGGGCTAAGCTTTGCAACTTATGCTGCAAATCGTGGTCATCAA
GTTAAAATTTTTGAAGCGAGCGAACAAATTGGTGGCCAATTTAATATCGCAAAGACCATACCTGGTAAAGAAGAGTTCTA
CGAAACATTACGTTATTTTAAGCGCCAGATCGAGTTGCAACCCAATATTGAGTTAATCTTGAATCATAAAGCAACACTGG
ATGAGCTTATGCAAGCCAGTTTTGATGAAATTGTGATTGCAACAGGCGTGATCCCAAGACATTTAAATATTCCAGGTATT
GATCATCCAAAAGTATTGAGTTATTTGGATGTGTTAAAAAACCGAAAACCTGTGGGTAAACGTATCGCTATTATTGGTGC
GGGTGGAATAGGCTTTGATACCGCAGAATTCCTGACGCACGAAGGTGAAAGTGCCAGTTTAAATCCTAAAAAATTCTATG
ATGAATGGGGAATTGATACCTCTTATGCGCATGTAGGTGGATTAAAGCAACCTGTGATTGAGGCATCGGAGCGAGAAATT
TATTTACTACAACGTAAAGCTTCGTCTGTAGGCGCCAATTTAGGAAAAACCACTGGCTGGATTCATCGCACAGGCTTAAA
ACATCGAAATGTCAAAATGATTGCTGGTGCTTCTTATGAAAAGATCGATGATCAAGGTTTACATATCATGATCGGCGATA
AAGCCACTGTTCTTGAGGTTGATAACGTAGTGATCTGTGCGGGTCAAGAATCTTATACTGCTATGTATGAGGCCTTACGT
GAGAGTGGCAAAAATGTGCATCTTATTGGTGGAGCCAAAGAAGCTGGTGAGCTGGATGCAAAACGTGCAATACGACAAGG
TGCAGAATTAGCGGCAACCCTCTAA

Upstream 100 bases:

>100_bases
CTGTCCAGATTATGCAATAAGTTGCATAAAAATCAAATCTTGTTTATAAATTAATGCAACATGTTGCACTAAGCAAGCTT
TTGCGAGCCACGGAGTTGTT

Downstream 100 bases:

>100_bases
TAATTTAATCATTTGAAAGGTTTAACTCACTTTATAGAGGGTTGAACCTTACAATTATTTGTTAATAGATTTTGCATTTT
TGAAAAAGCCAAAATATTTT

Product: 2,4-dienoyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 674; Mature: 673

Protein sequence:

>674_residues
MSFYPHLLAPLDLGFTTLKNRIMMGSMHIGLEEAPGGYERMAAFYAERAKGEVGLIVTGGIAPNDAGRTFAHASKLDTRE
EAVKHKIITQAVHDAGGKIAMQILHTGRYSYQQNIVAPSAIQAPINPIKPQELSSAEVWQTVSDFVNCAKLAQYAGYDGV
EIMGSEGYLINEFIAARTNHREDEWGGHYENRIRFPIEIVKRTRAEVGENFIIIYRLSMLDLVEGGSTLDEVIHLAKEIE
KAGATIINTGIGWHEARIPTIATKVPRAAFTWVTEKIRPHVKTPLITSNRINTPEMAEHVLANGQADLISMARPMLADPE
FALKAGEGRSDEINTCIGCNQACLDHIFTGTVASCLVNPRACHETELKFPQADKVKQIAVIGAGPAGLSFATYAANRGHQ
VKIFEASEQIGGQFNIAKTIPGKEEFYETLRYFKRQIELQPNIELILNHKATLDELMQASFDEIVIATGVIPRHLNIPGI
DHPKVLSYLDVLKNRKPVGKRIAIIGAGGIGFDTAEFLTHEGESASLNPKKFYDEWGIDTSYAHVGGLKQPVIEASEREI
YLLQRKASSVGANLGKTTGWIHRTGLKHRNVKMIAGASYEKIDDQGLHIMIGDKATVLEVDNVVICAGQESYTAMYEALR
ESGKNVHLIGGAKEAGELDAKRAIRQGAELAATL

Sequences:

>Translated_674_residues
MSFYPHLLAPLDLGFTTLKNRIMMGSMHIGLEEAPGGYERMAAFYAERAKGEVGLIVTGGIAPNDAGRTFAHASKLDTRE
EAVKHKIITQAVHDAGGKIAMQILHTGRYSYQQNIVAPSAIQAPINPIKPQELSSAEVWQTVSDFVNCAKLAQYAGYDGV
EIMGSEGYLINEFIAARTNHREDEWGGHYENRIRFPIEIVKRTRAEVGENFIIIYRLSMLDLVEGGSTLDEVIHLAKEIE
KAGATIINTGIGWHEARIPTIATKVPRAAFTWVTEKIRPHVKTPLITSNRINTPEMAEHVLANGQADLISMARPMLADPE
FALKAGEGRSDEINTCIGCNQACLDHIFTGTVASCLVNPRACHETELKFPQADKVKQIAVIGAGPAGLSFATYAANRGHQ
VKIFEASEQIGGQFNIAKTIPGKEEFYETLRYFKRQIELQPNIELILNHKATLDELMQASFDEIVIATGVIPRHLNIPGI
DHPKVLSYLDVLKNRKPVGKRIAIIGAGGIGFDTAEFLTHEGESASLNPKKFYDEWGIDTSYAHVGGLKQPVIEASEREI
YLLQRKASSVGANLGKTTGWIHRTGLKHRNVKMIAGASYEKIDDQGLHIMIGDKATVLEVDNVVICAGQESYTAMYEALR
ESGKNVHLIGGAKEAGELDAKRAIRQGAELAATL
>Mature_673_residues
SFYPHLLAPLDLGFTTLKNRIMMGSMHIGLEEAPGGYERMAAFYAERAKGEVGLIVTGGIAPNDAGRTFAHASKLDTREE
AVKHKIITQAVHDAGGKIAMQILHTGRYSYQQNIVAPSAIQAPINPIKPQELSSAEVWQTVSDFVNCAKLAQYAGYDGVE
IMGSEGYLINEFIAARTNHREDEWGGHYENRIRFPIEIVKRTRAEVGENFIIIYRLSMLDLVEGGSTLDEVIHLAKEIEK
AGATIINTGIGWHEARIPTIATKVPRAAFTWVTEKIRPHVKTPLITSNRINTPEMAEHVLANGQADLISMARPMLADPEF
ALKAGEGRSDEINTCIGCNQACLDHIFTGTVASCLVNPRACHETELKFPQADKVKQIAVIGAGPAGLSFATYAANRGHQV
KIFEASEQIGGQFNIAKTIPGKEEFYETLRYFKRQIELQPNIELILNHKATLDELMQASFDEIVIATGVIPRHLNIPGID
HPKVLSYLDVLKNRKPVGKRIAIIGAGGIGFDTAEFLTHEGESASLNPKKFYDEWGIDTSYAHVGGLKQPVIEASEREIY
LLQRKASSVGANLGKTTGWIHRTGLKHRNVKMIAGASYEKIDDQGLHIMIGDKATVLEVDNVVICAGQESYTAMYEALRE
SGKNVHLIGGAKEAGELDAKRAIRQGAELAATL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=670, Percent_Identity=62.6865671641791, Blast_Score=864, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=345, Percent_Identity=28.9855072463768, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17540738, Length=308, Percent_Identity=27.5974025974026, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17559802, Length=210, Percent_Identity=30.952380952381, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17564188, Length=306, Percent_Identity=27.1241830065359, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17565138, Length=308, Percent_Identity=25.6493506493506, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI72001454, Length=310, Percent_Identity=26.7741935483871, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17559804, Length=209, Percent_Identity=30.622009569378, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17566914, Length=312, Percent_Identity=26.6025641025641, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6325086, Length=216, Percent_Identity=28.7037037037037, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321973, Length=214, Percent_Identity=28.5046728971963, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 73857; Mature: 73726

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFYPHLLAPLDLGFTTLKNRIMMGSMHIGLEEAPGGYERMAAFYAERAKGEVGLIVTGG
CCCCCCHHHHHHCCHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECC
IAPNDAGRTFAHASKLDTREEAVKHKIITQAVHDAGGKIAMQILHTGRYSYQQNIVAPSA
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCHHHHCCCCCCHH
IQAPINPIKPQELSSAEVWQTVSDFVNCAKLAQYAGYDGVEIMGSEGYLINEFIAARTNH
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCC
REDEWGGHYENRIRFPIEIVKRTRAEVGENFIIIYRLSMLDLVEGGSTLDEVIHLAKEIE
CCCCCCCCCCCCEECHHHHHHHHHHHHCCCEEEEEEEHHHHHHCCCCHHHHHHHHHHHHH
KAGATIINTGIGWHEARIPTIATKVPRAAFTWVTEKIRPHVKTPLITSNRINTPEMAEHV
HCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHH
LANGQADLISMARPMLADPEFALKAGEGRSDEINTCIGCNQACLDHIFTGTVASCLVNPR
HHCCCHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCC
ACHETELKFPQADKVKQIAVIGAGPAGLSFATYAANRGHQVKIFEASEQIGGQFNIAKTI
CCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHCCCCCEEEEEECHHHCCCEEEEEECC
PGKEEFYETLRYFKRQIELQPNIELILNHKATLDELMQASFDEIVIATGVIPRHLNIPGI
CCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCHHCEEEECCCCCCCCCCCCC
DHPKVLSYLDVLKNRKPVGKRIAIIGAGGIGFDTAEFLTHEGESASLNPKKFYDEWGIDT
CCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCC
SYAHVGGLKQPVIEASEREIYLLQRKASSVGANLGKTTGWIHRTGLKHRNVKMIAGASYE
CHHHHCCCHHHHHCCCCCEEEEEEHHHHHHCCCCCCCCCCEECCCCCCCCEEEEECCCHH
KIDDQGLHIMIGDKATVLEVDNVVICAGQESYTAMYEALRESGKNVHLIGGAKEAGELDA
CCCCCCCEEEECCCEEEEEECCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
KRAIRQGAELAATL
HHHHHCCHHHHHCC
>Mature Secondary Structure 
SFYPHLLAPLDLGFTTLKNRIMMGSMHIGLEEAPGGYERMAAFYAERAKGEVGLIVTGG
CCCCCHHHHHHCCHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECC
IAPNDAGRTFAHASKLDTREEAVKHKIITQAVHDAGGKIAMQILHTGRYSYQQNIVAPSA
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCHHHHCCCCCCHH
IQAPINPIKPQELSSAEVWQTVSDFVNCAKLAQYAGYDGVEIMGSEGYLINEFIAARTNH
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCC
REDEWGGHYENRIRFPIEIVKRTRAEVGENFIIIYRLSMLDLVEGGSTLDEVIHLAKEIE
CCCCCCCCCCCCEECHHHHHHHHHHHHCCCEEEEEEEHHHHHHCCCCHHHHHHHHHHHHH
KAGATIINTGIGWHEARIPTIATKVPRAAFTWVTEKIRPHVKTPLITSNRINTPEMAEHV
HCCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHH
LANGQADLISMARPMLADPEFALKAGEGRSDEINTCIGCNQACLDHIFTGTVASCLVNPR
HHCCCHHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCC
ACHETELKFPQADKVKQIAVIGAGPAGLSFATYAANRGHQVKIFEASEQIGGQFNIAKTI
CCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHCCCCCEEEEEECHHHCCCEEEEEECC
PGKEEFYETLRYFKRQIELQPNIELILNHKATLDELMQASFDEIVIATGVIPRHLNIPGI
CCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCHHCEEEECCCCCCCCCCCCC
DHPKVLSYLDVLKNRKPVGKRIAIIGAGGIGFDTAEFLTHEGESASLNPKKFYDEWGIDT
CCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCC
SYAHVGGLKQPVIEASEREIYLLQRKASSVGANLGKTTGWIHRTGLKHRNVKMIAGASYE
CHHHHCCCHHHHHCCCCCEEEEEEHHHHHHCCCCCCCCCCEECCCCCCCCEEEEECCCHH
KIDDQGLHIMIGDKATVLEVDNVVICAGQESYTAMYEALRESGKNVHLIGGAKEAGELDA
CCCCCCCEEEECCCEEEEEECCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
KRAIRQGAELAATL
HHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]