Click here to switch to the map view.

The map label for this gene is paaG [H]

Identifier: 50084730

GI number: 50084730

Start: 1559560

End: 1560360

Strand: Direct

Name: paaG [H]

Synonym: ACIAD1568

Alternate gene names: 50084730

Gene position: 1559560-1560360 (Clockwise)

Preceding gene: 50084729

Following gene: 50084731

Centisome position: 43.34

GC content: 44.19

Gene sequence:

>801_bases
CTGCCAATGAGTCAGCATCTTTTAGTTGAAGTAGAAAAAGGTGTGGCGTATTTAACTTTAAATCGTCCCCAGCAAGGCAA
TGCGATTGATTTGGCACTTGCACAAGCGCTACTTCATGCTGCAATTCAATGTGATCAGGATCGAAGCATTCGCTGTGTTG
TCCTTACAGGGGCTGGACGTTTTTTCTGTGCTGGAGGTGATATTGCTGCATTTACTGAAGCTCAAGCGCAGGTACCTGCT
TTTTTAAGTGAGCTTGCGGGTATTTTACATTTAGCCATTTCGCGATTTATGCGTATGAACAAGCCTTTATTGGTGGTGGT
CAATGGAACTGCAGCAGGTGCTGGTATGAGTCTGGCGCTGATTGGGGATGTGGTTATTGCAGTTGAAAATGCGCAATTTG
CACCATCTTATGGGGCGATTGGTTTAAGTCCAGACGCTGGATTGACATGGCATTTGCCTAAATTGGTCGGTTTACGCAAA
GCCCAACAGATTTTAATACTCAATCAAAAACTGAGCGCTGCTGAAGCAGATCAAATCGGTCTGATTAGTGAAGTGGTCAC
CACTGAGCAACTGCAAAAGCGTCAAACTGCATTGATTGAGCAGTTGCTGAATAGTGCCACACCTGCGTTATCCAATGTCA
AACAGCTATTGTTGAATAGCCATCAAAATACCCTTGAAACACATCTGGAGCTTGAAGCGCGCAGTATTGCAGCAATCAGT
CTAGGTGAATCAGCCAAAGAAGGACTTGTGGCGTTTCTAGAAAAACGTGCAGCACAATTTAATCAGGATAGTGAAATATG
A

Upstream 100 bases:

>100_bases
AGGGGCGTGTCATTCGTGGATCTGCGGCCTCCATTCATGCCCAGGAACGTGCTAAAAGCTTCCCCATCTTGGCACGTCTC
GCGCGTGAAGCAATGGAGGC

Downstream 100 bases:

>100_bases
ATGTTGCTTATATTGTAGATGCGGTGCGTACCGCAGGCGGTCGTCGTAACGGTAAACTGGCTAGCTGGCATCCTGTTGAT
CTGGGTGCAGAAGTCATTAA

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MPMSQHLLVEVEKGVAYLTLNRPQQGNAIDLALAQALLHAAIQCDQDRSIRCVVLTGAGRFFCAGGDIAAFTEAQAQVPA
FLSELAGILHLAISRFMRMNKPLLVVVNGTAAGAGMSLALIGDVVIAVENAQFAPSYGAIGLSPDAGLTWHLPKLVGLRK
AQQILILNQKLSAAEADQIGLISEVVTTEQLQKRQTALIEQLLNSATPALSNVKQLLLNSHQNTLETHLELEARSIAAIS
LGESAKEGLVAFLEKRAAQFNQDSEI

Sequences:

>Translated_266_residues
MPMSQHLLVEVEKGVAYLTLNRPQQGNAIDLALAQALLHAAIQCDQDRSIRCVVLTGAGRFFCAGGDIAAFTEAQAQVPA
FLSELAGILHLAISRFMRMNKPLLVVVNGTAAGAGMSLALIGDVVIAVENAQFAPSYGAIGLSPDAGLTWHLPKLVGLRK
AQQILILNQKLSAAEADQIGLISEVVTTEQLQKRQTALIEQLLNSATPALSNVKQLLLNSHQNTLETHLELEARSIAAIS
LGESAKEGLVAFLEKRAAQFNQDSEI
>Mature_265_residues
PMSQHLLVEVEKGVAYLTLNRPQQGNAIDLALAQALLHAAIQCDQDRSIRCVVLTGAGRFFCAGGDIAAFTEAQAQVPAF
LSELAGILHLAISRFMRMNKPLLVVVNGTAAGAGMSLALIGDVVIAVENAQFAPSYGAIGLSPDAGLTWHLPKLVGLRKA
QQILILNQKLSAAEADQIGLISEVVTTEQLQKRQTALIEQLLNSATPALSNVKQLLLNSHQNTLETHLELEARSIAAISL
GESAKEGLVAFLEKRAAQFNQDSEI

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI260274832, Length=257, Percent_Identity=28.0155642023346, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI45643119, Length=257, Percent_Identity=28.0155642023346, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI260275230, Length=257, Percent_Identity=28.0155642023346, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI194097323, Length=248, Percent_Identity=29.8387096774194, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI25453481, Length=258, Percent_Identity=27.5193798449612, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI51538573, Length=258, Percent_Identity=27.5193798449612, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI4757968, Length=258, Percent_Identity=27.5193798449612, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI49355787, Length=258, Percent_Identity=27.5193798449612, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI37594469, Length=249, Percent_Identity=30.1204819277108, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI37594471, Length=249, Percent_Identity=30.1204819277108, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI4757966, Length=186, Percent_Identity=31.1827956989247, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI51538581, Length=186, Percent_Identity=31.1827956989247, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI221136756, Length=261, Percent_Identity=25.6704980842912, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI221136753, Length=261, Percent_Identity=25.6704980842912, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI221307494, Length=261, Percent_Identity=25.6704980842912, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI31542718, Length=253, Percent_Identity=23.3201581027668, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI70995211, Length=232, Percent_Identity=24.5689655172414, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI116235487, Length=254, Percent_Identity=22.8346456692913, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI150378541, Length=255, Percent_Identity=24.7058823529412, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4502327, Length=262, Percent_Identity=24.8091603053435, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1787660, Length=261, Percent_Identity=38.6973180076628, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787659, Length=256, Percent_Identity=34.375, Blast_Score=120, Evalue=7e-29,
Organism=Escherichia coli, GI221142681, Length=264, Percent_Identity=30.6818181818182, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788597, Length=257, Percent_Identity=29.1828793774319, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1790281, Length=197, Percent_Identity=27.9187817258883, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87082183, Length=262, Percent_Identity=22.5190839694656, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=31.0483870967742, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17535521, Length=257, Percent_Identity=27.2373540856031, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17554946, Length=258, Percent_Identity=29.0697674418605, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17549921, Length=221, Percent_Identity=28.9592760180996, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17560910, Length=185, Percent_Identity=25.9459459459459, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17534483, Length=229, Percent_Identity=27.5109170305677, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=184, Percent_Identity=25, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25144160, Length=248, Percent_Identity=25, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25144157, Length=248, Percent_Identity=25, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320241, Length=221, Percent_Identity=26.6968325791855, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI20129971, Length=254, Percent_Identity=32.6771653543307, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24653477, Length=254, Percent_Identity=32.6771653543307, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24654903, Length=188, Percent_Identity=28.1914893617021, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21357171, Length=198, Percent_Identity=29.2929292929293, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571729, Length=207, Percent_Identity=27.536231884058, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19922422, Length=267, Percent_Identity=25.8426966292135, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571730, Length=207, Percent_Identity=27.536231884058, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24653139, Length=258, Percent_Identity=25.5813953488372, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24650670, Length=187, Percent_Identity=32.0855614973262, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI19920382, Length=221, Percent_Identity=25.7918552036199, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28361; Mature: 28230

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMSQHLLVEVEKGVAYLTLNRPQQGNAIDLALAQALLHAAIQCDQDRSIRCVVLTGAGR
CCCCCCEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCE
FFCAGGDIAAFTEAQAQVPAFLSELAGILHLAISRFMRMNKPLLVVVNGTAAGAGMSLAL
EEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEE
IGDVVIAVENAQFAPSYGAIGLSPDAGLTWHLPKLVGLRKAQQILILNQKLSAAEADQIG
EEEEEEEEECCCCCCCCCCEEECCCCCCEEECHHHHHHHHHHHEEEECCCCCCCCCHHHH
LISEVVTTEQLQKRQTALIEQLLNSATPALSNVKQLLLNSHQNTLETHLELEARSIAAIS
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEE
LGESAKEGLVAFLEKRAAQFNQDSEI
CCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PMSQHLLVEVEKGVAYLTLNRPQQGNAIDLALAQALLHAAIQCDQDRSIRCVVLTGAGR
CCCCCEEEEEECCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCE
FFCAGGDIAAFTEAQAQVPAFLSELAGILHLAISRFMRMNKPLLVVVNGTAAGAGMSLAL
EEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEE
IGDVVIAVENAQFAPSYGAIGLSPDAGLTWHLPKLVGLRKAQQILILNQKLSAAEADQIG
EEEEEEEEECCCCCCCCCCEEECCCCCCEEECHHHHHHHHHHHEEEECCCCCCCCCHHHH
LISEVVTTEQLQKRQTALIEQLLNSATPALSNVKQLLLNSHQNTLETHLELEARSIAAIS
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEE
LGESAKEGLVAFLEKRAAQFNQDSEI
CCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]