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The map label for this gene is kdsC [H]

Identifier: 50084654

GI number: 50084654

Start: 1481628

End: 1482167

Strand: Direct

Name: kdsC [H]

Synonym: ACIAD1483

Alternate gene names: 50084654

Gene position: 1481628-1482167 (Clockwise)

Preceding gene: 50084653

Following gene: 50084655

Centisome position: 41.17

GC content: 42.78

Gene sequence:

>540_bases
ATGGCATCTTATGCATTGATCGAACAGGCTCGTCACCTTGAAGCATTGGTTTTAGACGTTGATGGAATTCTGAGTGACGG
TTTCGTGACGCTCACCAATACAGGTGATGAAATTAAATCATTTGATATTCGTGATGGTCTAGGCATGAAATTGGTTCAAC
AGGCTGGTTTAAAAGTGATTATTATCACGGGTCGAAAAAGTCAGATTGTTGAAAAACGTATGTCAGATTTAGGGGTTGAT
CTTGTTTTTCAGGGCAGAGAAGACAAAGGCATTGCTTTGAAAGAAGCGTGTGCGCACTTTAATTTGCTTCCTGAAGATTG
CCTGTATATGGGAGATGACTGGCCCGATTTATCTGCATTCTCAATTGCAGGGATGTGTGTGACGGTTCCAAACGGTCATA
GTGAGGTTCGTCGTCGAGCTGATCTGGTTACACAGGCTATGGGTGGTCGTGGTGCGGTCAGAGAAGTTTGTGATATGTTG
CTGAATGCAAAAGGAGTTTACGAAGAACTTCTTGCAAAATATCTAGCTGTACCCCATTAA

Upstream 100 bases:

>100_bases
TGAGAAAAAGATCAACCAGTTTGTTGTGGTTGATGACCAAAATAAAGTGATTGGTGTCATCAGTATGCATGACCTCATTC
AGGCAGGGGTAAGTTAATAC

Downstream 100 bases:

>100_bases
TAGTTTAATCGACCGAGAAAGGTGAGATACGCCGTATCATGGATACCAGAGCTCTTTATATTGCTGCTGTTGTAATCGCA
AGTATTAGTGGCGGTTACTA

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MASYALIEQARHLEALVLDVDGILSDGFVTLTNTGDEIKSFDIRDGLGMKLVQQAGLKVIIITGRKSQIVEKRMSDLGVD
LVFQGREDKGIALKEACAHFNLLPEDCLYMGDDWPDLSAFSIAGMCVTVPNGHSEVRRRADLVTQAMGGRGAVREVCDML
LNAKGVYEELLAKYLAVPH

Sequences:

>Translated_179_residues
MASYALIEQARHLEALVLDVDGILSDGFVTLTNTGDEIKSFDIRDGLGMKLVQQAGLKVIIITGRKSQIVEKRMSDLGVD
LVFQGREDKGIALKEACAHFNLLPEDCLYMGDDWPDLSAFSIAGMCVTVPNGHSEVRRRADLVTQAMGGRGAVREVCDML
LNAKGVYEELLAKYLAVPH
>Mature_178_residues
ASYALIEQARHLEALVLDVDGILSDGFVTLTNTGDEIKSFDIRDGLGMKLVQQAGLKVIIITGRKSQIVEKRMSDLGVDL
VFQGREDKGIALKEACAHFNLLPEDCLYMGDDWPDLSAFSIAGMCVTVPNGHSEVRRRADLVTQAMGGRGAVREVCDMLL
NAKGVYEELLAKYLAVPH

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Escherichia coli, GI2367202, Length=167, Percent_Identity=42.5149700598802, Blast_Score=143, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 19566; Mature: 19435

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASYALIEQARHLEALVLDVDGILSDGFVTLTNTGDEIKSFDIRDGLGMKLVQQAGLKVI
CCCHHHHHHHHHHHHHEEEHHHHHCCCEEEEECCCCHHHCCCCCCCCCHHHHHHCCCEEE
IITGRKSQIVEKRMSDLGVDLVFQGREDKGIALKEACAHFNLLPEDCLYMGDDWPDLSAF
EEECCHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCHH
SIAGMCVTVPNGHSEVRRRADLVTQAMGGRGAVREVCDMLLNAKGVYEELLAKYLAVPH
EECCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASYALIEQARHLEALVLDVDGILSDGFVTLTNTGDEIKSFDIRDGLGMKLVQQAGLKVI
CCHHHHHHHHHHHHHEEEHHHHHCCCEEEEECCCCHHHCCCCCCCCCHHHHHHCCCEEE
IITGRKSQIVEKRMSDLGVDLVFQGREDKGIALKEACAHFNLLPEDCLYMGDDWPDLSAF
EEECCHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCHH
SIAGMCVTVPNGHSEVRRRADLVTQAMGGRGAVREVCDMLLNAKGVYEELLAKYLAVPH
EECCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]