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The map label for this gene is fecR [H]

Identifier: 50084644

GI number: 50084644

Start: 1468497

End: 1469513

Strand: Direct

Name: fecR [H]

Synonym: ACIAD1471

Alternate gene names: 50084644

Gene position: 1468497-1469513 (Clockwise)

Preceding gene: 50084643

Following gene: 50084645

Centisome position: 40.81

GC content: 42.77

Gene sequence:

>1017_bases
ATGGCTATGGACAAAAGCAAACATCACCAACTGGTTGAAGAAGCCGCGTATTGGATCGTTCAACTGAGTTCGGATGATGA
ACGCTCGCGAAAAACCGCCAATCAAAAATTTGAAGAGTGGAAGAAAACCAGTGAGCAACATCGCCAAGTGGCTGCTGACA
TTGAACAGTGTATTGGATCAATTCAAAAACTTTCCCAAACCAGCGGACATAAAAAAGTCACCAAGGTTGCTCTTAAAGCT
GGCCTAAACTCAGGCAAAGCCTATAAACATTTGCGGGCAGGAACAGCTTTTGCCGTTGTCTTTGTTGCCATGAGTGGGGC
GCTATTTTATTTAACTGATACCACCGTGGCCTATGTGACTGCCGACATACAAGGGCAATCGGGGCAGTGGACCACGCAAA
CCTTACCAGATGGTTCACGTTTAATTTTACGCGGTAAAAGCGCAGTTAATCTTGATTTTAAAACCAACCAGCGAGTGGTT
GAGTTGGTGCAAGGTCAAATTTATGTTGATGTTGCCAAAGATAAAACCAGACCGTTTTTGGTCAAAACCAGTCATGGGCA
AATTCAGGCACTCGGCACAGCTTTTAGCGTCAGTTATGACCCTTCGGCAACTGAACTCAAAATGTTGCACTCAAAGGTAA
AAGTAGAAGCGACACAGGTTAAAACGACCCAATTGCACGCGACTCGTCAGGCCATTGTTGAAGCAGGGCAAGCCATTAAA
ATGGACAAAAATGGTGTACAAAAACTGCCTGTACTGAATATTTATAACGAACAGCAAAAATGGCAAAAGCATCAGCTTAT
GGTAGAAAACCTACCATTGAATCAAGTGCTACAAGAGTTAGACCGCAACTACAAAGGCAAAATTATTTTTAATGATGCGG
CATTGCAACATGTACGGGTTAATGCTGTGTTGCCTTTAGACCAAACCACAGAATCACTTAAGCTTTTGGCTACGGTTTTT
CCAGACCTGAAAATTAAGCAAATCATGCCGTTTGTGGTCATGGTTTCTTTAAAATAA

Upstream 100 bases:

>100_bases
CGAGCGTTTAAATGTGTCGACCAAAATGATTCAAAAATATTTGGCGAGTTGCTTAATTCAGTGCTACCAAAACCGACAAG
ACATGGACGCTTGCATTTAA

Downstream 100 bases:

>100_bases
TAAAAAATTAAATTTATTTTCAATTTTAGGTTCCACTTTTTTGAAAGTCGTTCGTCATAGTAAGTAGAAGCAATAAATAT
GGATCATTTTAATCAGTTGT

Product: iron ABC transporter transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MAMDKSKHHQLVEEAAYWIVQLSSDDERSRKTANQKFEEWKKTSEQHRQVAADIEQCIGSIQKLSQTSGHKKVTKVALKA
GLNSGKAYKHLRAGTAFAVVFVAMSGALFYLTDTTVAYVTADIQGQSGQWTTQTLPDGSRLILRGKSAVNLDFKTNQRVV
ELVQGQIYVDVAKDKTRPFLVKTSHGQIQALGTAFSVSYDPSATELKMLHSKVKVEATQVKTTQLHATRQAIVEAGQAIK
MDKNGVQKLPVLNIYNEQQKWQKHQLMVENLPLNQVLQELDRNYKGKIIFNDAALQHVRVNAVLPLDQTTESLKLLATVF
PDLKIKQIMPFVVMVSLK

Sequences:

>Translated_338_residues
MAMDKSKHHQLVEEAAYWIVQLSSDDERSRKTANQKFEEWKKTSEQHRQVAADIEQCIGSIQKLSQTSGHKKVTKVALKA
GLNSGKAYKHLRAGTAFAVVFVAMSGALFYLTDTTVAYVTADIQGQSGQWTTQTLPDGSRLILRGKSAVNLDFKTNQRVV
ELVQGQIYVDVAKDKTRPFLVKTSHGQIQALGTAFSVSYDPSATELKMLHSKVKVEATQVKTTQLHATRQAIVEAGQAIK
MDKNGVQKLPVLNIYNEQQKWQKHQLMVENLPLNQVLQELDRNYKGKIIFNDAALQHVRVNAVLPLDQTTESLKLLATVF
PDLKIKQIMPFVVMVSLK
>Mature_337_residues
AMDKSKHHQLVEEAAYWIVQLSSDDERSRKTANQKFEEWKKTSEQHRQVAADIEQCIGSIQKLSQTSGHKKVTKVALKAG
LNSGKAYKHLRAGTAFAVVFVAMSGALFYLTDTTVAYVTADIQGQSGQWTTQTLPDGSRLILRGKSAVNLDFKTNQRVVE
LVQGQIYVDVAKDKTRPFLVKTSHGQIQALGTAFSVSYDPSATELKMLHSKVKVEATQVKTTQLHATRQAIVEAGQAIKM
DKNGVQKLPVLNIYNEQQKWQKHQLMVENLPLNQVLQELDRNYKGKIIFNDAALQHVRVNAVLPLDQTTESLKLLATVFP
DLKIKQIMPFVVMVSLK

Specific function: Regulation of iron dicitrate transport. In the absence of citrate fecR inactivates fecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm [H]

COG id: COG3712

COG function: function code PT; Fe2+-dicitrate sensor, membrane component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790745, Length=217, Percent_Identity=30.8755760368664, Blast_Score=91, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006860
- InterPro:   IPR012373 [H]

Pfam domain/function: PF04773 FecR [H]

EC number: NA

Molecular weight: Translated: 37825; Mature: 37694

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMDKSKHHQLVEEAAYWIVQLSSDDERSRKTANQKFEEWKKTSEQHRQVAADIEQCIGS
CCCCCHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQKLSQTSGHKKVTKVALKAGLNSGKAYKHLRAGTAFAVVFVAMSGALFYLTDTTVAYVT
HHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHCCEEEEEECCEEEEEE
ADIQGQSGQWTTQTLPDGSRLILRGKSAVNLDFKTNQRVVELVQGQIYVDVAKDKTRPFL
EEECCCCCCEEECCCCCCCEEEEECCCEEEEEECCCHHHHHHHCCEEEEEEECCCCCCEE
VKTSHGQIQALGTAFSVSYDPSATELKMLHSKVKVEATQVKTTQLHATRQAIVEAGQAIK
EEECCCCEEEEEEEEEEECCCCHHHHHHHHHHHEEEHHHEEHHHHHHHHHHHHHCCCEEE
MDKNGVQKLPVLNIYNEQQKWQKHQLMVENLPLNQVLQELDRNYKGKIIFNDAALQHVRV
ECCCCCCCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEECHHEEEEEE
NAVLPLDQTTESLKLLATVFPDLKIKQIMPFVVMVSLK
EEEECCCCCHHHHHHHHHHCCCCCHHHHCCEEEEEECC
>Mature Secondary Structure 
AMDKSKHHQLVEEAAYWIVQLSSDDERSRKTANQKFEEWKKTSEQHRQVAADIEQCIGS
CCCCHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQKLSQTSGHKKVTKVALKAGLNSGKAYKHLRAGTAFAVVFVAMSGALFYLTDTTVAYVT
HHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHCCEEEEEECCEEEEEE
ADIQGQSGQWTTQTLPDGSRLILRGKSAVNLDFKTNQRVVELVQGQIYVDVAKDKTRPFL
EEECCCCCCEEECCCCCCCEEEEECCCEEEEEECCCHHHHHHHCCEEEEEEECCCCCCEE
VKTSHGQIQALGTAFSVSYDPSATELKMLHSKVKVEATQVKTTQLHATRQAIVEAGQAIK
EEECCCCEEEEEEEEEEECCCCHHHHHHHHHHHEEEHHHEEHHHHHHHHHHHHHCCCEEE
MDKNGVQKLPVLNIYNEQQKWQKHQLMVENLPLNQVLQELDRNYKGKIIFNDAALQHVRV
ECCCCCCCCCEEEECCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEECHHEEEEEE
NAVLPLDQTTESLKLLATVFPDLKIKQIMPFVVMVSLK
EEEECCCCCHHHHHHHHHHCCCCCHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2254251; 7610040; 9278503 [H]