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The map label for this gene is areR [H]

Identifier: 50084608

GI number: 50084608

Start: 1428191

End: 1429993

Strand: Reverse

Name: areR [H]

Synonym: ACIAD1431

Alternate gene names: 50084608

Gene position: 1429993-1428191 (Counterclockwise)

Preceding gene: 50084611

Following gene: 50084607

Centisome position: 39.74

GC content: 40.04

Gene sequence:

>1803_bases
ATGCAAATTTCATCAAGTCGTGACTGGTGCCAAGTTAAAGATTATTTTTATAAAACGGGTCAAGTTCCAGAACAAACCGA
GCTTGATCCAACCATTTTACAGATGTGGCATAAAGCCAAAGCAGCGGGCTTGAGCCCGTTCACGCCAGTTCCAGCTTCGA
CACAGCAGCCCCTAACCACAGACGATATTCGTCTATCTGAAACGGTTTTTCCTATTTTGAAAGATATTTGGGCGCTGTTT
AAACATCAGAATATTTGTACATTTTTCCTTAATACCCAATTTAAAATTATTGCCGAATATCAAAATCCTGACCCTCATTC
GCCCTATCATTTTTTAAAGCAAGGTCAAGTTCTGGATATTGCACAGTTTGGCAGTATTGCGCCCTCGTGTAGTATTTTGA
GTCAGATGCCGATCATTATGATGGGCCACCAGCATTATTTAAATGAATTTTCTGACTTTTACTGTGCATCGGTACCTGTG
TTCAATGGTCAGGGCAAAATACTGGGCGCGCTAGACATCACCTCGTATCGTGAACAACTGGCCAGTAACTGGCTAAGACA
CCTGCTTTATCAGGGGTATGTGGTTGAAAATGAAATTATAAAAAAGAATATGCCAGCACAGCATAAGCTGCTTTATTTTC
AGCATTCAGAAGATTTATTAAAAACAGCCTATACTGGCATGATTGAAATTGATGCCACGGGGCAGATTCAAAAAGCCAAT
CAAATGGCACTAACTCTACTCAACACGTCTATCGATCAATTATTGTATAAGCCCATTTCGAACTATTTCAGTTCGATAAG
TACCCTCGCCTCACTTGAGCAGCAGACGCAATTTATACGTAGTCAAGACGAAGCGCTGTTTTATGCACGTTTATACACGC
CCCAAATGACTAAAAAAACAAGCCACCTATTCAGCACATCTACACCCGATTTCAAAGATATTGCCAAATTAAGCAAAATC
TTGCATTCCGATGTACCCATTTTAATTACGGGTGCCACAGGCTCAGGTAAAGATCATTTGGCACGTCAAATTCACGAATT
TGCGACAAAAGATCAGGCATTTATTTCGATTAACTGTGCAGCTATTCCTGAACACTTACTTGAATCTGAACTTTTCGGCT
ATGAAGCAGGTGCTTTTACAGGAGCAAGTGCCAAAGGCAAACGTGGTTTGATCGAACTTGCTCATCAGGGCATTTTGTTT
TTAGATGAAATTGGTGATTTACCCAAACATTTACAGGCAAAATTATTACGCGTTTTACAAGATCAGGTTTTTTATCGTGT
AGGCGGTCATAAGCCGATTCAAAGTCAGTTCAAATTAATTTCTGCCACCCATCAAGATCTATTGGCAATGATTGACAATC
ATGACTTCAGAAGTGATTTGTATTACAGAATATGTGGCTATCAGATCGAGTTACCGCAACTCAAAGACCGTCCAGATAAA
ATTGATATTTTTAAGACACTGCTGGCCAACGCCAAAATTTACAGTTGGTCGGTCAATGTTCAAGAACAGTTCGAGCACTA
TGATTGGCCAGGAAACATTCGAGAATTGACTCATGTGATTCAACTTTCTGCGGCGCTTATAGCGCATGATTCTCTTGAAC
ATGCGCATCTTGAACATTTACATGTACCACAGCAACGAAAAGTTACGCCCCAATCCTACCTAGCAAATAAACCTCAAACT
TCACTGAATCAGATGACTAAACAGCTCGTTTTAGACATTTTGCAACAAGAAAAAGGCAACATCTCTCAAGCCGCTAAGCG
ACTCAATATCTCAAGAACAACACTGTATAAGTATTTACAGTAA

Upstream 100 bases:

>100_bases
CTTTGCTATAGTCAAAAAAGATTCAATGGACGATGAAAAGATGATGTTGTTTCGGATGTAGTCGCGAGCAACGTTTCTTT
GTTTTTGAAGGATTCAAACT

Downstream 100 bases:

>100_bases
TAAGCTCAAGGACAGTATTGTACATTGTTCAGATTCTGGACAATGTACAATTCAATAGTGTCCAGCCCCTGAACAATTAC
CCGAAAATTTAAAAAAATTA

Product: sigma(54)-dependent transcriptionnal regulator for areCBA operon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 600; Mature: 600

Protein sequence:

>600_residues
MQISSSRDWCQVKDYFYKTGQVPEQTELDPTILQMWHKAKAAGLSPFTPVPASTQQPLTTDDIRLSETVFPILKDIWALF
KHQNICTFFLNTQFKIIAEYQNPDPHSPYHFLKQGQVLDIAQFGSIAPSCSILSQMPIIMMGHQHYLNEFSDFYCASVPV
FNGQGKILGALDITSYREQLASNWLRHLLYQGYVVENEIIKKNMPAQHKLLYFQHSEDLLKTAYTGMIEIDATGQIQKAN
QMALTLLNTSIDQLLYKPISNYFSSISTLASLEQQTQFIRSQDEALFYARLYTPQMTKKTSHLFSTSTPDFKDIAKLSKI
LHSDVPILITGATGSGKDHLARQIHEFATKDQAFISINCAAIPEHLLESELFGYEAGAFTGASAKGKRGLIELAHQGILF
LDEIGDLPKHLQAKLLRVLQDQVFYRVGGHKPIQSQFKLISATHQDLLAMIDNHDFRSDLYYRICGYQIELPQLKDRPDK
IDIFKTLLANAKIYSWSVNVQEQFEHYDWPGNIRELTHVIQLSAALIAHDSLEHAHLEHLHVPQQRKVTPQSYLANKPQT
SLNQMTKQLVLDILQQEKGNISQAAKRLNISRTTLYKYLQ

Sequences:

>Translated_600_residues
MQISSSRDWCQVKDYFYKTGQVPEQTELDPTILQMWHKAKAAGLSPFTPVPASTQQPLTTDDIRLSETVFPILKDIWALF
KHQNICTFFLNTQFKIIAEYQNPDPHSPYHFLKQGQVLDIAQFGSIAPSCSILSQMPIIMMGHQHYLNEFSDFYCASVPV
FNGQGKILGALDITSYREQLASNWLRHLLYQGYVVENEIIKKNMPAQHKLLYFQHSEDLLKTAYTGMIEIDATGQIQKAN
QMALTLLNTSIDQLLYKPISNYFSSISTLASLEQQTQFIRSQDEALFYARLYTPQMTKKTSHLFSTSTPDFKDIAKLSKI
LHSDVPILITGATGSGKDHLARQIHEFATKDQAFISINCAAIPEHLLESELFGYEAGAFTGASAKGKRGLIELAHQGILF
LDEIGDLPKHLQAKLLRVLQDQVFYRVGGHKPIQSQFKLISATHQDLLAMIDNHDFRSDLYYRICGYQIELPQLKDRPDK
IDIFKTLLANAKIYSWSVNVQEQFEHYDWPGNIRELTHVIQLSAALIAHDSLEHAHLEHLHVPQQRKVTPQSYLANKPQT
SLNQMTKQLVLDILQQEKGNISQAAKRLNISRTTLYKYLQ
>Mature_600_residues
MQISSSRDWCQVKDYFYKTGQVPEQTELDPTILQMWHKAKAAGLSPFTPVPASTQQPLTTDDIRLSETVFPILKDIWALF
KHQNICTFFLNTQFKIIAEYQNPDPHSPYHFLKQGQVLDIAQFGSIAPSCSILSQMPIIMMGHQHYLNEFSDFYCASVPV
FNGQGKILGALDITSYREQLASNWLRHLLYQGYVVENEIIKKNMPAQHKLLYFQHSEDLLKTAYTGMIEIDATGQIQKAN
QMALTLLNTSIDQLLYKPISNYFSSISTLASLEQQTQFIRSQDEALFYARLYTPQMTKKTSHLFSTSTPDFKDIAKLSKI
LHSDVPILITGATGSGKDHLARQIHEFATKDQAFISINCAAIPEHLLESELFGYEAGAFTGASAKGKRGLIELAHQGILF
LDEIGDLPKHLQAKLLRVLQDQVFYRVGGHKPIQSQFKLISATHQDLLAMIDNHDFRSDLYYRICGYQIELPQLKDRPDK
IDIFKTLLANAKIYSWSVNVQEQFEHYDWPGNIRELTHVIQLSAALIAHDSLEHAHLEHLHVPQQRKVTPQSYLANKPQT
SLNQMTKQLVLDILQQEKGNISQAAKRLNISRTTLYKYLQ

Specific function: Required For Induction Of Expression Of The Hydrogenase- 4 Structural Genes. [C]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=302, Percent_Identity=41.0596026490066, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1788550, Length=315, Percent_Identity=39.0476190476191, Blast_Score=205, Evalue=8e-54,
Organism=Escherichia coli, GI1789233, Length=415, Percent_Identity=32.5301204819277, Blast_Score=201, Evalue=9e-53,
Organism=Escherichia coli, GI1789087, Length=302, Percent_Identity=38.7417218543046, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1788905, Length=288, Percent_Identity=37.8472222222222, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1790437, Length=315, Percent_Identity=33.968253968254, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1786524, Length=312, Percent_Identity=36.5384615384615, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1790299, Length=320, Percent_Identity=32.8125, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI87081872, Length=316, Percent_Identity=34.1772151898734, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI87082152, Length=321, Percent_Identity=32.7102803738318, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1787583, Length=305, Percent_Identity=31.4754098360656, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1789828, Length=187, Percent_Identity=39.0374331550802, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI87081858, Length=579, Percent_Identity=23.4887737478411, Blast_Score=126, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 68397; Mature: 68397

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQISSSRDWCQVKDYFYKTGQVPEQTELDPTILQMWHKAKAAGLSPFTPVPASTQQPLTT
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
DDIRLSETVFPILKDIWALFKHQNICTFFLNTQFKIIAEYQNPDPHSPYHFLKQGQVLDI
CCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCCCCHHHHCCCCEEEH
AQFGSIAPSCSILSQMPIIMMGHQHYLNEFSDFYCASVPVFNGQGKILGALDITSYREQL
HHHCCCCCCHHHHHCCCEEEECCHHHHHHHHHHHEEECEEECCCCCEEEEEHHHHHHHHH
ASNWLRHLLYQGYVVENEIIKKNMPAQHKLLYFQHSEDLLKTAYTGMIEIDATGQIQKAN
HHHHHHHHHHCCEEEEHHHHHCCCCCHHEEEEEECCHHHHHHHHCCEEEECCCCCCHHHH
QMALTLLNTSIDQLLYKPISNYFSSISTLASLEQQTQFIRSQDEALFYARLYTPQMTKKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHH
SHLFSTSTPDFKDIAKLSKILHSDVPILITGATGSGKDHLARQIHEFATKDQAFISINCA
HHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEHH
AIPEHLLESELFGYEAGAFTGASAKGKRGLIELAHQGILFLDEIGDLPKHLQAKLLRVLQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCEEEEHHHCCCHHHHHHHHHHHHH
DQVFYRVGGHKPIQSQFKLISATHQDLLAMIDNHDFRSDLYYRICGYQIELPQLKDRPDK
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCEEECCCCCCCCCH
IDIFKTLLANAKIYSWSVNVQEQFEHYDWPGNIRELTHVIQLSAALIAHDSLEHAHLEHL
HHHHHHHHHCCEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HVPQQRKVTPQSYLANKPQTSLNQMTKQLVLDILQQEKGNISQAAKRLNISRTTLYKYLQ
CCCHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MQISSSRDWCQVKDYFYKTGQVPEQTELDPTILQMWHKAKAAGLSPFTPVPASTQQPLTT
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
DDIRLSETVFPILKDIWALFKHQNICTFFLNTQFKIIAEYQNPDPHSPYHFLKQGQVLDI
CCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCCCCHHHHCCCCEEEH
AQFGSIAPSCSILSQMPIIMMGHQHYLNEFSDFYCASVPVFNGQGKILGALDITSYREQL
HHHCCCCCCHHHHHCCCEEEECCHHHHHHHHHHHEEECEEECCCCCEEEEEHHHHHHHHH
ASNWLRHLLYQGYVVENEIIKKNMPAQHKLLYFQHSEDLLKTAYTGMIEIDATGQIQKAN
HHHHHHHHHHCCEEEEHHHHHCCCCCHHEEEEEECCHHHHHHHHCCEEEECCCCCCHHHH
QMALTLLNTSIDQLLYKPISNYFSSISTLASLEQQTQFIRSQDEALFYARLYTPQMTKKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHH
SHLFSTSTPDFKDIAKLSKILHSDVPILITGATGSGKDHLARQIHEFATKDQAFISINCA
HHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEHH
AIPEHLLESELFGYEAGAFTGASAKGKRGLIELAHQGILFLDEIGDLPKHLQAKLLRVLQ
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCEEEEHHHCCCHHHHHHHHHHHHH
DQVFYRVGGHKPIQSQFKLISATHQDLLAMIDNHDFRSDLYYRICGYQIELPQLKDRPDK
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCEEECCCCCCCCCH
IDIFKTLLANAKIYSWSVNVQEQFEHYDWPGNIRELTHVIQLSAALIAHDSLEHAHLEHL
HHHHHHHHHCCEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HVPQQRKVTPQSYLANKPQTSLNQMTKQLVLDILQQEKGNISQAAKRLNISRTTLYKYLQ
CCCHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA