| Definition | Acinetobacter sp. ADP1 chromosome, complete genome. |
|---|---|
| Accession | NC_005966 |
| Length | 3,598,621 |
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The map label for this gene is clpA [H]
Identifier: 50084542
GI number: 50084542
Start: 1358102
End: 1360378
Strand: Direct
Name: clpA [H]
Synonym: ACIAD1363
Alternate gene names: 50084542
Gene position: 1358102-1360378 (Clockwise)
Preceding gene: 50084541
Following gene: 50084543
Centisome position: 37.74
GC content: 43.0
Gene sequence:
>2277_bases ATGCTCAGTCGTCAATTAGAAGTGTCCTTACGTTTGGCTGTAAGCATGGCTCGTCAAAAAAGGCACGAATTTCTTACTGT AGAACATTTGTTGCTGGCTTTGCTCGATAATGATTCGGCTGTCAATGCGCTTAAAGCGTGTGGTGCTGATATTGTTTCAT TACGTAAAGAATTAGAAGAATACGTCGAACAACATACACCAAAACTTGGAGAGAATAGCGAACAAGCGCCGCATCCTACC GAAAGTTTTGACCGTATCTTGCAAAGAGCCATTTTCCATGTGCAATCAAGCGGTGGTGATCGTACCGTAGAAGGTGCAGA TGTTTTAGTTGCAATGTACTCTGAGCGTGACTCGTTTGCTGTATATCTACTTAAACGCCATCAGATCAATCGTCTTACAC TGACACAGTATCTTTCCCATGGCACACGTAAAGAAGATGTGCAGTCAGAAGAAGAAGTTGAAGACATTGAAGGTGAGTCT TCATCCTCATCGAATGCTGGGCCTTTGGAGCAGTTCACCCTAAATCTGAATAATGAAGCGCTAAAAGGTAAAACTGATCC TTTGATCGGGCGTGAAAAAGAAATTGAGCGCACAGCGCAAATTCTATGCCGTCGTCGCAAAAACAATCCATTGCTCGTGG GAGATCCAGGCGTTGGTAAAACTTCTATTGCAGAAGGTTTGGCATGGCTAATTGTAAATGGCAAGGCACCTAAGCCTCTT GCCCATGCAGAAGTCTATAGCCTTGATATTGGTGCACTGGTTGCAGGTACAAAATATCGTGGTGATTTTGAAAAACGTTT AAAGCAGCTTCTTAACGCATTGAAGAAAAATCCAAATGCGATCTTATTTATCGATGAGATTCACATGATTATTGGTGCAG GCTCAAGTATGGGCAGTACCATGGATGCTTCGAACTTGATTAAACCTGCGCTAGCGAATGGTACGTTGCGTTGCATTGGT TCTACCACATTTCAAGAATATCGTCAGGTATTTGAAAAAGACCATGCTTTGTCACGCCGTTTTCAAAAGATCGATGTGAA TGAGCCAAGTATTACCGAGACAATCGAAATTTTACGTGGACTCAAAACCAAATTTGAAGATTTTCACCATGTGGAATATG ACGATAAAGCGCTAGTTGCCGCAGTGGAATTGTCTTCCAAATTTATCAATGATCGTTTCTTGCCCGATAAGGCGATTGAT GTGATTGATGAAGCAGGTGCTCAGCGTCGTTTGAAAGCTGAAAAAGATGGTAGTTTGATTACGACTGAAAATATTGAAGA TATCGTGTCTAAAATTGCGCGCATCCCACCAAAAACAGTATCTAAAGATGACAAGGCGGTGCTTGAATATCTTGAACGTG ATCTCAAGCGCGTTGTATTTGGTCAGGATGAAGCGATTACAGCCTTGGCTTCGGCGATCAAGTTATCTCGGGCTGGTTTG AAAGCTCCAGATAAGCCTGTAGGTAATTTTGTTTTTGCTGGGCCAACAGGCGTAGGTAAAACAGAGGTGACCAAGCAGCT TGCCAAGTTGTTGGGCGTAGAATTGGTACGTTTTGACATGTCTGAATACATGGAGCGCCATGCAGTATCTCGTTTGATTG GTGCGCCTCCTGGTTATGTTGGATATGATCAAGGTGGCTTATTGACGGATGCGATTCATAAGAATCCACATTGTGTCTTA TTGCTTGATGAGATTGAAAAGGCGCATCCAGATGTATTTAACTTGTTATTGCAGGTGATGGATCATGGTGCCTTGACCGA TAATAACGGTCGTAAGTCTGATTTTAGGAATGTTATTATTGTATTGACAACCAATATTGGTGCTGAAAGCATTTCAAGAA CCAGCATTGGTTTTACCGAGCAAGACAATAGTAACGACAATCAGGAAGCAATGAAACGCGCATTCTCGCCAGAGTTTCGC AACCGTCTGGATGGCGTGATTCAATTCAAATCGCTTCCAAATGCTGTCATTGAGTCAGTGGTTGATAAATTCCTGACAGA GTTACAAGCACAATTGGATGATAAAAAGGTGGTGCTTGAAGTCGATCAATCTGCACGTGATTGGTTGTCTGCCAATGGTT ATGATCGCCTCATGGGGGCACGTCCAATGCAGCGTCTGATTCAAGAGCATTTGAAAAAGCCTTTGGCCGAAATGATTTTA TTCGGTGAGCTTGCAGATCATGGTGGCAATGTGGCTGTCTCTGTGAAGAAAGAAGATGGTAAAGAGGTGGGGCTACAGCT TTCCGTCTTTGAGGATCAAACAGCTGAGCCTGCTTAA
Upstream 100 bases:
>100_bases AGACATTGCGGAAACAAAAGCGAACCAAGTAAACAACTATGCTCGGTCTCAAGGTCATCCATTACTTTGTCAGATTGAGC CCAAAGATTAAGGGGGTCGT
Downstream 100 bases:
>100_bases TTTATGTTAGATGACATTTCAATAACCCGAATACTGAGTGTATTCGGGTTATTTATATTGACTGCGCTTGCTGAAATTCT GGGCTGTTATTTTCCTTATC
Product: ATP-binding protease component
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 758; Mature: 758
Protein sequence:
>758_residues MLSRQLEVSLRLAVSMARQKRHEFLTVEHLLLALLDNDSAVNALKACGADIVSLRKELEEYVEQHTPKLGENSEQAPHPT ESFDRILQRAIFHVQSSGGDRTVEGADVLVAMYSERDSFAVYLLKRHQINRLTLTQYLSHGTRKEDVQSEEEVEDIEGES SSSSNAGPLEQFTLNLNNEALKGKTDPLIGREKEIERTAQILCRRRKNNPLLVGDPGVGKTSIAEGLAWLIVNGKAPKPL AHAEVYSLDIGALVAGTKYRGDFEKRLKQLLNALKKNPNAILFIDEIHMIIGAGSSMGSTMDASNLIKPALANGTLRCIG STTFQEYRQVFEKDHALSRRFQKIDVNEPSITETIEILRGLKTKFEDFHHVEYDDKALVAAVELSSKFINDRFLPDKAID VIDEAGAQRRLKAEKDGSLITTENIEDIVSKIARIPPKTVSKDDKAVLEYLERDLKRVVFGQDEAITALASAIKLSRAGL KAPDKPVGNFVFAGPTGVGKTEVTKQLAKLLGVELVRFDMSEYMERHAVSRLIGAPPGYVGYDQGGLLTDAIHKNPHCVL LLDEIEKAHPDVFNLLLQVMDHGALTDNNGRKSDFRNVIIVLTTNIGAESISRTSIGFTEQDNSNDNQEAMKRAFSPEFR NRLDGVIQFKSLPNAVIESVVDKFLTELQAQLDDKKVVLEVDQSARDWLSANGYDRLMGARPMQRLIQEHLKKPLAEMIL FGELADHGGNVAVSVKKEDGKEVGLQLSVFEDQTAEPA
Sequences:
>Translated_758_residues MLSRQLEVSLRLAVSMARQKRHEFLTVEHLLLALLDNDSAVNALKACGADIVSLRKELEEYVEQHTPKLGENSEQAPHPT ESFDRILQRAIFHVQSSGGDRTVEGADVLVAMYSERDSFAVYLLKRHQINRLTLTQYLSHGTRKEDVQSEEEVEDIEGES SSSSNAGPLEQFTLNLNNEALKGKTDPLIGREKEIERTAQILCRRRKNNPLLVGDPGVGKTSIAEGLAWLIVNGKAPKPL AHAEVYSLDIGALVAGTKYRGDFEKRLKQLLNALKKNPNAILFIDEIHMIIGAGSSMGSTMDASNLIKPALANGTLRCIG STTFQEYRQVFEKDHALSRRFQKIDVNEPSITETIEILRGLKTKFEDFHHVEYDDKALVAAVELSSKFINDRFLPDKAID VIDEAGAQRRLKAEKDGSLITTENIEDIVSKIARIPPKTVSKDDKAVLEYLERDLKRVVFGQDEAITALASAIKLSRAGL KAPDKPVGNFVFAGPTGVGKTEVTKQLAKLLGVELVRFDMSEYMERHAVSRLIGAPPGYVGYDQGGLLTDAIHKNPHCVL LLDEIEKAHPDVFNLLLQVMDHGALTDNNGRKSDFRNVIIVLTTNIGAESISRTSIGFTEQDNSNDNQEAMKRAFSPEFR NRLDGVIQFKSLPNAVIESVVDKFLTELQAQLDDKKVVLEVDQSARDWLSANGYDRLMGARPMQRLIQEHLKKPLAEMIL FGELADHGGNVAVSVKKEDGKEVGLQLSVFEDQTAEPA >Mature_758_residues MLSRQLEVSLRLAVSMARQKRHEFLTVEHLLLALLDNDSAVNALKACGADIVSLRKELEEYVEQHTPKLGENSEQAPHPT ESFDRILQRAIFHVQSSGGDRTVEGADVLVAMYSERDSFAVYLLKRHQINRLTLTQYLSHGTRKEDVQSEEEVEDIEGES SSSSNAGPLEQFTLNLNNEALKGKTDPLIGREKEIERTAQILCRRRKNNPLLVGDPGVGKTSIAEGLAWLIVNGKAPKPL AHAEVYSLDIGALVAGTKYRGDFEKRLKQLLNALKKNPNAILFIDEIHMIIGAGSSMGSTMDASNLIKPALANGTLRCIG STTFQEYRQVFEKDHALSRRFQKIDVNEPSITETIEILRGLKTKFEDFHHVEYDDKALVAAVELSSKFINDRFLPDKAID VIDEAGAQRRLKAEKDGSLITTENIEDIVSKIARIPPKTVSKDDKAVLEYLERDLKRVVFGQDEAITALASAIKLSRAGL KAPDKPVGNFVFAGPTGVGKTEVTKQLAKLLGVELVRFDMSEYMERHAVSRLIGAPPGYVGYDQGGLLTDAIHKNPHCVL LLDEIEKAHPDVFNLLLQVMDHGALTDNNGRKSDFRNVIIVLTTNIGAESISRTSIGFTEQDNSNDNQEAMKRAFSPEFR NRLDGVIQFKSLPNAVIESVVDKFLTELQAQLDDKKVVLEVDQSARDWLSANGYDRLMGARPMQRLIQEHLKKPLAEMIL FGELADHGGNVAVSVKKEDGKEVGLQLSVFEDQTAEPA
Specific function: ATP-dependent specificity component of the ClpP protease. It directs the protease to specific substrates. The primary function of the ClpA-ClpP complex appears to be the degradation of unfolded or abnormal proteins [H]
COG id: COG0542
COG function: function code O; ATPases with chaperone activity, ATP-binding subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the clpA/clpB family [H]
Homologues:
Organism=Homo sapiens, GI13540606, Length=299, Percent_Identity=30.7692307692308, Blast_Score=152, Evalue=1e-36, Organism=Escherichia coli, GI1787109, Length=744, Percent_Identity=61.9623655913978, Blast_Score=922, Evalue=0.0, Organism=Escherichia coli, GI1788943, Length=414, Percent_Identity=43.4782608695652, Blast_Score=301, Evalue=1e-82, Organism=Saccharomyces cerevisiae, GI6320464, Length=324, Percent_Identity=47.2222222222222, Blast_Score=298, Evalue=3e-81, Organism=Saccharomyces cerevisiae, GI6323002, Length=409, Percent_Identity=36.919315403423, Blast_Score=241, Evalue=4e-64,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR013093 - InterPro: IPR003959 - InterPro: IPR018368 - InterPro: IPR001270 - InterPro: IPR019489 - InterPro: IPR004176 - InterPro: IPR013461 - InterPro: IPR023150 [H]
Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]
EC number: NA
Molecular weight: Translated: 84066; Mature: 84066
Theoretical pI: Translated: 5.77; Mature: 5.77
Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLSRQLEVSLRLAVSMARQKRHEFLTVEHLLLALLDNDSAVNALKACGADIVSLRKELEE CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHH YVEQHTPKLGENSEQAPHPTESFDRILQRAIFHVQSSGGDRTVEGADVLVAMYSERDSFA HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEEECCCCCEE VYLLKRHQINRLTLTQYLSHGTRKEDVQSEEEVEDIEGESSSSSNAGPLEQFTLNLNNEA EEEHHHHCCCHHHHHHHHHCCCCCHHCCCHHHHHHHCCCCCCCCCCCCHHHEEEECCCCC LKGKTDPLIGREKEIERTAQILCRRRKNNPLLVGDPGVGKTSIAEGLAWLIVNGKAPKPL CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCEEEEEECCCCCCCC AHAEVYSLDIGALVAGTKYRGDFEKRLKQLLNALKKNPNAILFIDEIHMIIGAGSSMGST CHHHEEEECHHHHEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEHHHHCCCCCCCCC MDASNLIKPALANGTLRCIGSTTFQEYRQVFEKDHALSRRFQKIDVNEPSITETIEILRG CCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH LKTKFEDFHHVEYDDKALVAAVELSSKFINDRFLPDKAIDVIDEAGAQRRLKAEKDGSLI HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHCCCCCCCEE TTENIEDIVSKIARIPPKTVSKDDKAVLEYLERDLKRVVFGQDEAITALASAIKLSRAGL EECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC KAPDKPVGNFVFAGPTGVGKTEVTKQLAKLLGVELVRFDMSEYMERHAVSRLIGAPPGYV CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC GYDQGGLLTDAIHKNPHCVLLLDEIEKAHPDVFNLLLQVMDHGALTDNNGRKSDFRNVII CCCCCCCCHHHHCCCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE VLTTNIGAESISRTSIGFTEQDNSNDNQEAMKRAFSPEFRNRLDGVIQFKSLPNAVIESV EEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHEEHHHCCHHHHHHH VDKFLTELQAQLDDKKVVLEVDQSARDWLSANGYDRLMGARPMQRLIQEHLKKPLAEMIL HHHHHHHHHHHCCCCEEEEEECHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH FGELADHGGNVAVSVKKEDGKEVGLQLSVFEDQTAEPA HHHHHCCCCCEEEEEECCCCCHHCEEEEEECCCCCCCC >Mature Secondary Structure MLSRQLEVSLRLAVSMARQKRHEFLTVEHLLLALLDNDSAVNALKACGADIVSLRKELEE CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHH YVEQHTPKLGENSEQAPHPTESFDRILQRAIFHVQSSGGDRTVEGADVLVAMYSERDSFA HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEEECCCCCEE VYLLKRHQINRLTLTQYLSHGTRKEDVQSEEEVEDIEGESSSSSNAGPLEQFTLNLNNEA EEEHHHHCCCHHHHHHHHHCCCCCHHCCCHHHHHHHCCCCCCCCCCCCHHHEEEECCCCC LKGKTDPLIGREKEIERTAQILCRRRKNNPLLVGDPGVGKTSIAEGLAWLIVNGKAPKPL CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCEEEEEECCCCCCCC AHAEVYSLDIGALVAGTKYRGDFEKRLKQLLNALKKNPNAILFIDEIHMIIGAGSSMGST CHHHEEEECHHHHEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEHHHHCCCCCCCCC MDASNLIKPALANGTLRCIGSTTFQEYRQVFEKDHALSRRFQKIDVNEPSITETIEILRG CCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH LKTKFEDFHHVEYDDKALVAAVELSSKFINDRFLPDKAIDVIDEAGAQRRLKAEKDGSLI HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHCCCCCCCEE TTENIEDIVSKIARIPPKTVSKDDKAVLEYLERDLKRVVFGQDEAITALASAIKLSRAGL EECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC KAPDKPVGNFVFAGPTGVGKTEVTKQLAKLLGVELVRFDMSEYMERHAVSRLIGAPPGYV CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC GYDQGGLLTDAIHKNPHCVLLLDEIEKAHPDVFNLLLQVMDHGALTDNNGRKSDFRNVII CCCCCCCCHHHHCCCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE VLTTNIGAESISRTSIGFTEQDNSNDNQEAMKRAFSPEFRNRLDGVIQFKSLPNAVIESV EEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHEEHHHCCHHHHHHH VDKFLTELQAQLDDKKVVLEVDQSARDWLSANGYDRLMGARPMQRLIQEHLKKPLAEMIL HHHHHHHHHHHCCCCEEEEEECHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH FGELADHGGNVAVSVKKEDGKEVGLQLSVFEDQTAEPA HHHHHCCCCCEEEEEECCCCCHHCEEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]