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The map label for this gene is 50084476

Identifier: 50084476

GI number: 50084476

Start: 1294680

End: 1295432

Strand: Direct

Name: 50084476

Synonym: ACIAD1293

Alternate gene names: NA

Gene position: 1294680-1295432 (Clockwise)

Preceding gene: 50084473

Following gene: 50084478

Centisome position: 35.98

GC content: 40.5

Gene sequence:

>753_bases
ATGAATCAACATTTCGCCATTAATCCAGTTGAATGGGAGGCACGCTGTCAACTGGCAGCCCTTTATCGCTTAATCGCATA
TTATAAAATGACCGATTTGATTGACACGCATATCAGCTTACGCGTGCCAGATGAACCTCATCATTTTTTGATTAATCGTT
ATGGCGTTTTGTTTGATCATATGTGCGCATCAGATTTGGTCAAGATTGATCATGATGGAAAAATTGTCGAAAACTATGAT
CAAGGCAAGAAAGTGAATGTCGCGGGTTTTGTCATTCATTCTGCTATTCATCATGCTAAACCGCATTTAGATTGTGTCAT
TCATACGCATACCGCAGACGGTATTGCTGTATCTGCGCAGCAAGATGGGTTATTACCTATATCACAACATGCGCTCAAAT
TTTATCGCCGTTTGTCTTATCACAGCTATGAAGGAATTGCGTTATCACTCGAAGAGCGAGAACGACTGGTCAATGACTTA
GGTAATAACAAAGCCATGATACTCAGGAACCATGGTTTATTAGCAGCAGGGCCGTCTGTCGCACATGCATTTCATGAAAT
CTATTTTTTGGAGCGCGCTTGTCAGATTCAGGTAAAAGCTTTATCAGCACACAACTTAATTTATCCTTCCGAAGCTCTAT
GTGAATTTACAGCTTCTCAGTTTGAGCAGGATGATGCTGAGGGAATTATTTGGGATGCGTGGCATGCTGCTTTATCATTG
ATTGAAAAAGATAAAGCAGATTTTTGTCGTTAG

Upstream 100 bases:

>100_bases
AGTAAATACGAATCAGCAGAAGTAAAAAATCAACGATGATAAGTATGAGATCGGGTTTTTAAAAATCGAGTACTAAATAT
TTTGAGTAAGAGAGCATTGA

Downstream 100 bases:

>100_bases
CTGCTAAATATATTTCGACATAATATTGCGGAATTTCTGAATGATTGGATCTTTGCTGCGACCGCGTCGCATAATGAGAG
AAAATGGCGCTTGATAACCG

Product: aldolase II superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNQHFAINPVEWEARCQLAALYRLIAYYKMTDLIDTHISLRVPDEPHHFLINRYGVLFDHMCASDLVKIDHDGKIVENYD
QGKKVNVAGFVIHSAIHHAKPHLDCVIHTHTADGIAVSAQQDGLLPISQHALKFYRRLSYHSYEGIALSLEERERLVNDL
GNNKAMILRNHGLLAAGPSVAHAFHEIYFLERACQIQVKALSAHNLIYPSEALCEFTASQFEQDDAEGIIWDAWHAALSL
IEKDKADFCR

Sequences:

>Translated_250_residues
MNQHFAINPVEWEARCQLAALYRLIAYYKMTDLIDTHISLRVPDEPHHFLINRYGVLFDHMCASDLVKIDHDGKIVENYD
QGKKVNVAGFVIHSAIHHAKPHLDCVIHTHTADGIAVSAQQDGLLPISQHALKFYRRLSYHSYEGIALSLEERERLVNDL
GNNKAMILRNHGLLAAGPSVAHAFHEIYFLERACQIQVKALSAHNLIYPSEALCEFTASQFEQDDAEGIIWDAWHAALSL
IEKDKADFCR
>Mature_250_residues
MNQHFAINPVEWEARCQLAALYRLIAYYKMTDLIDTHISLRVPDEPHHFLINRYGVLFDHMCASDLVKIDHDGKIVENYD
QGKKVNVAGFVIHSAIHHAKPHLDCVIHTHTADGIAVSAQQDGLLPISQHALKFYRRLSYHSYEGIALSLEERERLVNDL
GNNKAMILRNHGLLAAGPSVAHAFHEIYFLERACQIQVKALSAHNLIYPSEALCEFTASQFEQDDAEGIIWDAWHAALSL
IEKDKADFCR

Specific function: Unknown

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family [H]

Homologues:

Organism=Homo sapiens, GI29826321, Length=190, Percent_Identity=46.8421052631579, Blast_Score=167, Evalue=6e-42,
Organism=Homo sapiens, GI29826325, Length=190, Percent_Identity=46.8421052631579, Blast_Score=163, Evalue=1e-40,
Organism=Homo sapiens, GI29826323, Length=190, Percent_Identity=46.8421052631579, Blast_Score=163, Evalue=1e-40,
Organism=Homo sapiens, GI29826319, Length=190, Percent_Identity=46.8421052631579, Blast_Score=162, Evalue=2e-40,
Organism=Homo sapiens, GI9257190, Length=198, Percent_Identity=40.9090909090909, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI89276787, Length=198, Percent_Identity=40.9090909090909, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI297307158, Length=198, Percent_Identity=40.9090909090909, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI9257192, Length=198, Percent_Identity=40.9090909090909, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI297307160, Length=198, Percent_Identity=40.9090909090909, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI9951927, Length=191, Percent_Identity=39.7905759162304, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI62912453, Length=191, Percent_Identity=39.7905759162304, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI9943848, Length=191, Percent_Identity=39.7905759162304, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI115533218, Length=198, Percent_Identity=41.9191919191919, Blast_Score=167, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI115533216, Length=198, Percent_Identity=41.9191919191919, Blast_Score=167, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI71989560, Length=199, Percent_Identity=35.678391959799, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71989550, Length=199, Percent_Identity=35.678391959799, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71989555, Length=199, Percent_Identity=35.678391959799, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71989544, Length=199, Percent_Identity=35.678391959799, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71989541, Length=199, Percent_Identity=35.678391959799, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281363755, Length=202, Percent_Identity=36.1386138613861, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281363751, Length=202, Percent_Identity=36.1386138613861, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24655690, Length=202, Percent_Identity=36.1386138613861, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24655685, Length=188, Percent_Identity=36.7021276595745, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI281363761, Length=188, Percent_Identity=36.7021276595745, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281363759, Length=188, Percent_Identity=36.7021276595745, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281363753, Length=188, Percent_Identity=36.7021276595745, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281363763, Length=188, Percent_Identity=36.7021276595745, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281363757, Length=188, Percent_Identity=36.7021276595745, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI17136738, Length=188, Percent_Identity=36.7021276595745, Blast_Score=125, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: NA

Molecular weight: Translated: 28374; Mature: 28374

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQHFAINPVEWEARCQLAALYRLIAYYKMTDLIDTHISLRVPDEPHHFLINRYGVLFDH
CCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHH
MCASDLVKIDHDGKIVENYDQGKKVNVAGFVIHSAIHHAKPHLDCVIHTHTADGIAVSAQ
HHHHHCEEECCCCCEEECCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEECC
QDGLLPISQHALKFYRRLSYHSYEGIALSLEERERLVNDLGNNKAMILRNHGLLAAGPSV
CCCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCEEEEECCCCEEECHHH
AHAFHEIYFLERACQIQVKALSAHNLIYPSEALCEFTASQFEQDDAEGIIWDAWHAALSL
HHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
IEKDKADFCR
HHHHHHHCCC
>Mature Secondary Structure
MNQHFAINPVEWEARCQLAALYRLIAYYKMTDLIDTHISLRVPDEPHHFLINRYGVLFDH
CCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHH
MCASDLVKIDHDGKIVENYDQGKKVNVAGFVIHSAIHHAKPHLDCVIHTHTADGIAVSAQ
HHHHHCEEECCCCCEEECCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEECC
QDGLLPISQHALKFYRRLSYHSYEGIALSLEERERLVNDLGNNKAMILRNHGLLAAGPSV
CCCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCEEEEECCCCEEECHHH
AHAFHEIYFLERACQIQVKALSAHNLIYPSEALCEFTASQFEQDDAEGIIWDAWHAALSL
HHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHH
IEKDKADFCR
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]