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The map label for this gene is astB

Identifier: 50084472

GI number: 50084472

Start: 1289875

End: 1291215

Strand: Direct

Name: astB

Synonym: ACIAD1288

Alternate gene names: 50084472

Gene position: 1289875-1291215 (Clockwise)

Preceding gene: 50084471

Following gene: 50084473

Centisome position: 35.84

GC content: 43.1

Gene sequence:

>1341_bases
ATGTCTGGTTATGAAATTAATTTTGATGGTTTAGTTGGCCCGACACATCACTATGCAGGTTTGTCGTTTGGCAATGAAGC
ATCGACCAAAAACCGTAATCATCTTTCTAATCCTAAGCTTGCAGCCAAACAAGGACTGCTAAAGATGAAAGCATTGGCAG
ATATGGGCATGAAGCAGGGCGTTCTAGCGCCACAGGAGCGTCCGCATGTACCCAGCTTACGTAAGCTGGGCTTTGGTGGA
GATGATCACGCTGTCATTACTCAAGCCATGCGCACTTCGCCAGAGTTACTATCGGCTTTGAGTTCAGCTTCATGTATGTG
GACTGCAAATGCTGCAACCGTTTCACCTTCGGCAGATAGTGCTGATGGTCGTGTTCATTTTACTGCCGCAAATTTGAATA
ACAAATTTCATCGTTCAATCGAACATGAAACAACGAGTCAAATTCTGGCTGCGATTTTTCGTGATGAGCGCTATTTTGCG
CATCACTTAGCGTTACCGCCAGTCGCTTTATTCGGTGATGAAGGCGCTGCCAATCATAATCGTTTAGGTGGTCCTTACGA
TTCTGCTGCTGTTCAGGTGTTTGTATATGGTCAACAATTTCTAGGTGGTCAAGTTGCACCCAAGCGTTATCCAGCGCGTC
AGTCTCTAGAAGCCTGTCAGGCCGTTGCACGATTACACCAACTTGACTCAAATCGCACTGTATTTGTTCAGCAAAATCCT
GATGTGATTGATGAAGGTGTATTTCATAACGATGTGATTGCAGTAAGTAACCAGCAAGTTTTATTTCATCATCAAAAAGC
TTTTTTCAATCAAGCTCAGGCGCTTAATGAAATTCGTGAAAAAATGGCACTGTTAGAACAAGACTTGATTGCCATTGAAG
TGCCAGATCAACGGGTCAGTGTCGGAGATGCGGTATCGACTTATTTATTTAATAGTCAATTGATTACGCGTCCTGATGGT
GGTATGACTATTGTTGTACCAGAAGAATCTCGTCAAAACCTTGCGGTATGGTCATATCTGAATGACATGATTCAGATGGG
AACACCTGTCGATCAGATCAAAGTTTTTGATTTGCGTGAAAGTATGCGTAATGGTGGTGGACCTGCATGTTTACGTTTAC
GTGTCGCAGTGAATGACGCAGAGTTCAATGCGATTAATCACAATGTACTGATGAACGATGCATTGTTTGCACGTCTAAAT
ACTTGGGTTGATCGGCGTTATCGTGATCAGCTCTCACATCAAGATTTGGCAGATCCTGCATTATTGATCGAAAGTCGTAG
TGCATTGGATGAATTGACCCAAATTTTAAATCTGGGCTCGGTCTATCATTTTCAACAATAG

Upstream 100 bases:

>100_bases
GCGTGGCCGATGGCTTCTTTAGAGAGTGAGCAGTTGAGTCTGCCAGAAAAATTATCACCAGGCATTGTGCTGTAGTGAGT
CAACAGAAATGGAGTTAAAA

Downstream 100 bases:

>100_bases
AATGGGAAGCATGAGCCAATGACACATTTTCTTCATTCAGTATTGAGCCAGCAATTTCCTCACGCATTACAAGGTGAAAA
CCATAATTTTTCATGGCAAT

Product: succinylarginine dihydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSGYEINFDGLVGPTHHYAGLSFGNEASTKNRNHLSNPKLAAKQGLLKMKALADMGMKQGVLAPQERPHVPSLRKLGFGG
DDHAVITQAMRTSPELLSALSSASCMWTANAATVSPSADSADGRVHFTAANLNNKFHRSIEHETTSQILAAIFRDERYFA
HHLALPPVALFGDEGAANHNRLGGPYDSAAVQVFVYGQQFLGGQVAPKRYPARQSLEACQAVARLHQLDSNRTVFVQQNP
DVIDEGVFHNDVIAVSNQQVLFHHQKAFFNQAQALNEIREKMALLEQDLIAIEVPDQRVSVGDAVSTYLFNSQLITRPDG
GMTIVVPEESRQNLAVWSYLNDMIQMGTPVDQIKVFDLRESMRNGGGPACLRLRVAVNDAEFNAINHNVLMNDALFARLN
TWVDRRYRDQLSHQDLADPALLIESRSALDELTQILNLGSVYHFQQ

Sequences:

>Translated_446_residues
MSGYEINFDGLVGPTHHYAGLSFGNEASTKNRNHLSNPKLAAKQGLLKMKALADMGMKQGVLAPQERPHVPSLRKLGFGG
DDHAVITQAMRTSPELLSALSSASCMWTANAATVSPSADSADGRVHFTAANLNNKFHRSIEHETTSQILAAIFRDERYFA
HHLALPPVALFGDEGAANHNRLGGPYDSAAVQVFVYGQQFLGGQVAPKRYPARQSLEACQAVARLHQLDSNRTVFVQQNP
DVIDEGVFHNDVIAVSNQQVLFHHQKAFFNQAQALNEIREKMALLEQDLIAIEVPDQRVSVGDAVSTYLFNSQLITRPDG
GMTIVVPEESRQNLAVWSYLNDMIQMGTPVDQIKVFDLRESMRNGGGPACLRLRVAVNDAEFNAINHNVLMNDALFARLN
TWVDRRYRDQLSHQDLADPALLIESRSALDELTQILNLGSVYHFQQ
>Mature_445_residues
SGYEINFDGLVGPTHHYAGLSFGNEASTKNRNHLSNPKLAAKQGLLKMKALADMGMKQGVLAPQERPHVPSLRKLGFGGD
DHAVITQAMRTSPELLSALSSASCMWTANAATVSPSADSADGRVHFTAANLNNKFHRSIEHETTSQILAAIFRDERYFAH
HLALPPVALFGDEGAANHNRLGGPYDSAAVQVFVYGQQFLGGQVAPKRYPARQSLEACQAVARLHQLDSNRTVFVQQNPD
VIDEGVFHNDVIAVSNQQVLFHHQKAFFNQAQALNEIREKMALLEQDLIAIEVPDQRVSVGDAVSTYLFNSQLITRPDGG
MTIVVPEESRQNLAVWSYLNDMIQMGTPVDQIKVFDLRESMRNGGGPACLRLRVAVNDAEFNAINHNVLMNDALFARLNT
WVDRRYRDQLSHQDLADPALLIESRSALDELTQILNLGSVYHFQQ

Specific function: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)

COG id: COG3724

COG function: function code E; Succinylarginine dihydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinylarginine dihydrolase family

Homologues:

Organism=Escherichia coli, GI1788041, Length=446, Percent_Identity=61.2107623318386, Blast_Score=561, Evalue=1e-161,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASTB_ACIAD (Q6FCP9)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045982.1
- HSSP:   P76216
- ProteinModelPortal:   Q6FCP9
- SMR:   Q6FCP9
- STRING:   Q6FCP9
- GeneID:   2880678
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1288
- NMPDR:   fig|62977.3.peg.411
- eggNOG:   COG3724
- HOGENOM:   HBG289862
- OMA:   HFAHHPA
- PhylomeDB:   Q6FCP9
- ProtClustDB:   PRK13281
- BioCyc:   ASP62977:ACIAD1288-MONOMER
- HAMAP:   MF_01172
- InterPro:   IPR007079
- Gene3D:   G3DSA:3.75.10.20
- TIGRFAMs:   TIGR03241

Pfam domain/function: PF04996 AstB

EC number: =3.5.3.23

Molecular weight: Translated: 49301; Mature: 49170

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: ACT_SITE 174-174 ACT_SITE 249-249 ACT_SITE 370-370 BINDING 110-110 BINDING 213-213 BINDING 251-251 BINDING 364-364

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGYEINFDGLVGPTHHYAGLSFGNEASTKNRNHLSNPKLAAKQGLLKMKALADMGMKQG
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHCC
VLAPQERPHVPSLRKLGFGGDDHAVITQAMRTSPELLSALSSASCMWTANAATVSPSADS
CCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHCCHHHHHHHHCCCEEEECCCCEECCCCCC
ADGRVHFTAANLNNKFHRSIEHETTSQILAAIFRDERYFAHHLALPPVALFGDEGAANHN
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCCCCCC
RLGGPYDSAAVQVFVYGQQFLGGQVAPKRYPARQSLEACQAVARLHQLDSNRTVFVQQNP
CCCCCCCCCEEEEEEECHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCC
DVIDEGVFHNDVIAVSNQQVLFHHQKAFFNQAQALNEIREKMALLEQDLIAIEVPDQRVS
CHHHCCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
VGDAVSTYLFNSQLITRPDGGMTIVVPEESRQNLAVWSYLNDMIQMGTPVDQIKVFDLRE
HHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHEEEHHHHH
SMRNGGGPACLRLRVAVNDAEFNAINHNVLMNDALFARLNTWVDRRYRDQLSHQDLADPA
HHHCCCCCEEEEEEEEECCCCCCEECCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LLIESRSALDELTQILNLGSVYHFQQ
HHHHHHHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure 
SGYEINFDGLVGPTHHYAGLSFGNEASTKNRNHLSNPKLAAKQGLLKMKALADMGMKQG
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHCC
VLAPQERPHVPSLRKLGFGGDDHAVITQAMRTSPELLSALSSASCMWTANAATVSPSADS
CCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHCCHHHHHHHHCCCEEEECCCCEECCCCCC
ADGRVHFTAANLNNKFHRSIEHETTSQILAAIFRDERYFAHHLALPPVALFGDEGAANHN
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCCCCCCC
RLGGPYDSAAVQVFVYGQQFLGGQVAPKRYPARQSLEACQAVARLHQLDSNRTVFVQQNP
CCCCCCCCCEEEEEEECHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCC
DVIDEGVFHNDVIAVSNQQVLFHHQKAFFNQAQALNEIREKMALLEQDLIAIEVPDQRVS
CHHHCCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
VGDAVSTYLFNSQLITRPDGGMTIVVPEESRQNLAVWSYLNDMIQMGTPVDQIKVFDLRE
HHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHEEEHHHHH
SMRNGGGPACLRLRVAVNDAEFNAINHNVLMNDALFARLNTWVDRRYRDQLSHQDLADPA
HHHCCCCCEEEEEEEEECCCCCCEECCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LLIESRSALDELTQILNLGSVYHFQQ
HHHHHHHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA