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The map label for this gene is dat [H]

Identifier: 50084399

GI number: 50084399

Start: 1212116

End: 1213486

Strand: Direct

Name: dat [H]

Synonym: ACIAD1210

Alternate gene names: 50084399

Gene position: 1212116-1213486 (Clockwise)

Preceding gene: 50084397

Following gene: 50084400

Centisome position: 33.68

GC content: 44.93

Gene sequence:

>1371_bases
ATGAGCGTTAATTCCGTAAATCCTGCCACCAATTCCACCAACGAATATTACCTGACTCGCCAAAGTCAGATGGAATCAAA
TGTTCGTAGCTATCCGCGCAAGTTACCTCTTGCCATAGCTCGTGCACAAGGTTGCTGGGTTACAGATGTTGAAGGTACAC
AATACCTCGATTGTTTAGCGGGGGCAGGGACCTTGGCTCTAGGCCATAATCATCCTGCTGTTATTCAAAGTATTCAAGAC
ACCCTTGCAAGTGGTTTGCCGTTGCATACTTTGGATCTTACAACTCCTTTGAAAGATGCATTTACTGAAGCATTACTGTC
TTTCCTGCCAGGCGGGAAAGAAGAATATTGCTTACAGTTCTGTGGTCCATCTGGTGCAGATGCGACTGAAGCAGCAATCA
AACTTGCGAAAACCTATACAGGTCGCAGCTCAGTCATCAGTTTTTCTGGTGGTTACCATGGTATGACCCATGGTTCACTG
GCGATGACAGGCAACTTGAGCGCGAAAAATTCTGTCAATAATTTAATGCCAGGTGTTCAGTTCATGCCGTATCCGCATGA
ATACCGTTGTCCGCTTGGCTTGGGTGGTGAAGCGGGTGTCGATGCACTCACTTACTACTTTGAAAACTTTATCGAAGATG
TTGAAAGCGGTGTAACCAAACCAGCAGCAGTCATTCTTGAAGCAATTCAAGGTGAAGGTGGTGTAGTGACTGCACCTGTA
AAATGGTTGCAAAAAATCCGTGAAGTGACTGAGCGTCATAACATCGTTTTGATTTTGGATGAAGTACAGGCTGGTTTTGG
TCGTTCAGGCAAAATGTTTGCATTTGAACACGCCGATATCGAGCCTGACGTTGTGGTGATGTCTAAAGCTGTGGGTGGGG
GTTTACCGCTTGCAGTATTGGGTATCAAGCGTAAGTTTGATGCATGGCAACCAGCAGGTCATACAGGTACATTCCGTGGC
AACCAGTTGGCTATGGGCACAGGTTTAGTTGTTCTTGACACGATCAAAAATGAAAATCTTGCTCAAAATGCCCAAGAGCG
CGGTGAATTCTTACAAGCTGAATTGAAGAAGCTGGCCAATGAATTTCCATGCATTGGAAACGTACGTGGTCGTGGCTTGA
TGATTGGTGTTGAGATTGTCGATGAACGTCAATCTGCTGATCGTATTGGCTCGTTACCTGCAGATGCACAATTGGCTGCC
GCAATTCAAACAGCATGTTTCAATAACAAGCTTTTACTTGAGAAAGGTGGTCGTAACGGTAGTGTTATCCGTTTACTTTG
CCCATTGATTATTACTCAAGATGAATGTGTTCAAGTGATTGAACGTTTCAAGAAATCAGTTGCAGAAGCACTCAAAGCGG
TTCGAGGCTAA

Upstream 100 bases:

>100_bases
AGCAATTGCTATTTTACTAGAATCCTACAAGCACCGAGTCAAAGGACCGCAAGTCACCAGACTTATTTCTTTCAACCCTT
ATCAGAGATGGTAATCCGAT

Downstream 100 bases:

>100_bases
AAACATATGGTTGATTTTGCAGAACATCGTAAAGCTTTGCTCTGTAATGATGCTGCATCCATTGCTGAATATCAGTCAGC
AATGGATGAGGCAGTGAAAG

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MSVNSVNPATNSTNEYYLTRQSQMESNVRSYPRKLPLAIARAQGCWVTDVEGTQYLDCLAGAGTLALGHNHPAVIQSIQD
TLASGLPLHTLDLTTPLKDAFTEALLSFLPGGKEEYCLQFCGPSGADATEAAIKLAKTYTGRSSVISFSGGYHGMTHGSL
AMTGNLSAKNSVNNLMPGVQFMPYPHEYRCPLGLGGEAGVDALTYYFENFIEDVESGVTKPAAVILEAIQGEGGVVTAPV
KWLQKIREVTERHNIVLILDEVQAGFGRSGKMFAFEHADIEPDVVVMSKAVGGGLPLAVLGIKRKFDAWQPAGHTGTFRG
NQLAMGTGLVVLDTIKNENLAQNAQERGEFLQAELKKLANEFPCIGNVRGRGLMIGVEIVDERQSADRIGSLPADAQLAA
AIQTACFNNKLLLEKGGRNGSVIRLLCPLIITQDECVQVIERFKKSVAEALKAVRG

Sequences:

>Translated_456_residues
MSVNSVNPATNSTNEYYLTRQSQMESNVRSYPRKLPLAIARAQGCWVTDVEGTQYLDCLAGAGTLALGHNHPAVIQSIQD
TLASGLPLHTLDLTTPLKDAFTEALLSFLPGGKEEYCLQFCGPSGADATEAAIKLAKTYTGRSSVISFSGGYHGMTHGSL
AMTGNLSAKNSVNNLMPGVQFMPYPHEYRCPLGLGGEAGVDALTYYFENFIEDVESGVTKPAAVILEAIQGEGGVVTAPV
KWLQKIREVTERHNIVLILDEVQAGFGRSGKMFAFEHADIEPDVVVMSKAVGGGLPLAVLGIKRKFDAWQPAGHTGTFRG
NQLAMGTGLVVLDTIKNENLAQNAQERGEFLQAELKKLANEFPCIGNVRGRGLMIGVEIVDERQSADRIGSLPADAQLAA
AIQTACFNNKLLLEKGGRNGSVIRLLCPLIITQDECVQVIERFKKSVAEALKAVRG
>Mature_455_residues
SVNSVNPATNSTNEYYLTRQSQMESNVRSYPRKLPLAIARAQGCWVTDVEGTQYLDCLAGAGTLALGHNHPAVIQSIQDT
LASGLPLHTLDLTTPLKDAFTEALLSFLPGGKEEYCLQFCGPSGADATEAAIKLAKTYTGRSSVISFSGGYHGMTHGSLA
MTGNLSAKNSVNNLMPGVQFMPYPHEYRCPLGLGGEAGVDALTYYFENFIEDVESGVTKPAAVILEAIQGEGGVVTAPVK
WLQKIREVTERHNIVLILDEVQAGFGRSGKMFAFEHADIEPDVVVMSKAVGGGLPLAVLGIKRKFDAWQPAGHTGTFRGN
QLAMGTGLVVLDTIKNENLAQNAQERGEFLQAELKKLANEFPCIGNVRGRGLMIGVEIVDERQSADRIGSLPADAQLAAA
IQTACFNNKLLLEKGGRNGSVIRLLCPLIITQDECVQVIERFKKSVAEALKAVRG

Specific function: 4-aminobutyrate (GABA) degradation. [C]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=460, Percent_Identity=30.6521739130435, Blast_Score=192, Evalue=8e-49,
Organism=Homo sapiens, GI37574042, Length=420, Percent_Identity=30.7142857142857, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI24119277, Length=443, Percent_Identity=27.9909706546275, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI4557809, Length=432, Percent_Identity=27.5462962962963, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI226442705, Length=420, Percent_Identity=30.4761904761905, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI226442709, Length=389, Percent_Identity=30.0771208226221, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI284507298, Length=336, Percent_Identity=27.9761904761905, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI188536080, Length=380, Percent_Identity=26.3157894736842, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI38679950, Length=380, Percent_Identity=26.3157894736842, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI38679946, Length=380, Percent_Identity=26.3157894736842, Blast_Score=100, Evalue=5e-21,
Organism=Escherichia coli, GI1789016, Length=447, Percent_Identity=33.7807606263982, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI145693181, Length=412, Percent_Identity=32.5242718446602, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1787560, Length=424, Percent_Identity=34.4339622641509, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1788044, Length=443, Percent_Identity=28.4424379232506, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1789759, Length=423, Percent_Identity=26.241134751773, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1786349, Length=385, Percent_Identity=27.012987012987, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1786991, Length=316, Percent_Identity=28.1645569620253, Blast_Score=108, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI32564660, Length=434, Percent_Identity=32.4884792626728, Blast_Score=195, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI71992977, Length=444, Percent_Identity=27.4774774774775, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI25144271, Length=441, Percent_Identity=27.437641723356, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI25144274, Length=235, Percent_Identity=31.4893617021277, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17541228, Length=383, Percent_Identity=26.8929503916449, Blast_Score=96, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=367, Percent_Identity=30.5177111716621, Blast_Score=166, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6323470, Length=430, Percent_Identity=28.8372093023256, Blast_Score=160, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6321456, Length=377, Percent_Identity=27.8514588859416, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28574759, Length=462, Percent_Identity=30.952380952381, Blast_Score=205, Evalue=7e-53,
Organism=Drosophila melanogaster, GI161085790, Length=463, Percent_Identity=31.1015118790497, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21356575, Length=465, Percent_Identity=28.6021505376344, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI21357415, Length=432, Percent_Identity=25.6944444444444, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI281366494, Length=443, Percent_Identity=25.2821670428894, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24667139, Length=443, Percent_Identity=25.2821670428894, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24667143, Length=443, Percent_Identity=25.2821670428894, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 48951; Mature: 48819

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNSVNPATNSTNEYYLTRQSQMESNVRSYPRKLPLAIARAQGCWVTDVEGTQYLDCLA
CCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCHHEEECCCCEEEECCCCHHHHHHH
GAGTLALGHNHPAVIQSIQDTLASGLPLHTLDLTTPLKDAFTEALLSFLPGGKEEYCLQF
CCCEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHEE
CGPSGADATEAAIKLAKTYTGRSSVISFSGGYHGMTHGSLAMTGNLSAKNSVNNLMPGVQ
CCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEECCCCCHHHHHHHCCCCE
FMPYPHEYRCPLGLGGEAGVDALTYYFENFIEDVESGVTKPAAVILEAIQGEGGVVTAPV
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEHHH
KWLQKIREVTERHNIVLILDEVQAGFGRSGKMFAFEHADIEPDVVVMSKAVGGGLPLAVL
HHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEECCCCCCCEEEEEHHCCCCCCEEEE
GIKRKFDAWQPAGHTGTFRGNQLAMGTGLVVLDTIKNENLAQNAQERGEFLQAELKKLAN
EHHHHCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
EFPCIGNVRGRGLMIGVEIVDERQSADRIGSLPADAQLAAAIQTACFNNKLLLEKGGRNG
HCCCCCCCCCCEEEEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCC
SVIRLLCPLIITQDECVQVIERFKKSVAEALKAVRG
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVNSVNPATNSTNEYYLTRQSQMESNVRSYPRKLPLAIARAQGCWVTDVEGTQYLDCLA
CCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCHHEEECCCCEEEECCCCHHHHHHH
GAGTLALGHNHPAVIQSIQDTLASGLPLHTLDLTTPLKDAFTEALLSFLPGGKEEYCLQF
CCCEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCHHHHHEE
CGPSGADATEAAIKLAKTYTGRSSVISFSGGYHGMTHGSLAMTGNLSAKNSVNNLMPGVQ
CCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEECCCCCHHHHHHHCCCCE
FMPYPHEYRCPLGLGGEAGVDALTYYFENFIEDVESGVTKPAAVILEAIQGEGGVVTAPV
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEHHH
KWLQKIREVTERHNIVLILDEVQAGFGRSGKMFAFEHADIEPDVVVMSKAVGGGLPLAVL
HHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEECCCCCCCEEEEEHHCCCCCCEEEE
GIKRKFDAWQPAGHTGTFRGNQLAMGTGLVVLDTIKNENLAQNAQERGEFLQAELKKLAN
EHHHHCCCCCCCCCCCCCCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
EFPCIGNVRGRGLMIGVEIVDERQSADRIGSLPADAQLAAAIQTACFNNKLLLEKGGRNG
HCCCCCCCCCCEEEEEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCC
SVIRLLCPLIITQDECVQVIERFKKSVAEALKAVRG
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9260954 [H]