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The map label for this gene is ybgF [H]

Identifier: 50084340

GI number: 50084340

Start: 1138259

End: 1139650

Strand: Reverse

Name: ybgF [H]

Synonym: ACIAD1147

Alternate gene names: 50084340

Gene position: 1139650-1138259 (Counterclockwise)

Preceding gene: 50084341

Following gene: 50084339

Centisome position: 31.67

GC content: 43.32

Gene sequence:

>1392_bases
GTGCTCGATAGTGCTGCACCCTTAAAACGAGCCATGAGTACCCGTCATTTGGTTATGCTGTCATTAGGCGGTGCGATTGG
TACAGGGTTGTTTCTTGGTTCAGGGGAAGTCATTACCCAGACAGGGCCGATTGGAGCAGTGATTGCCTATATGCTTGGCG
GTTTGATTGCATATATGGTGATGTTATGTCTGGGTGAACTGGCCGTACACATGCCTGTATCAGGATCTTTCGGCGCTTAT
GCCAAAAAATACATCGGGCCAGGCACAGGCTACATGATTTCATGGGTTTACTGGCTCACATGGACAGCAACGCTGGGTAC
CGAATTTACAGCCGCTGCATTACTCATGCAGGAATGGTTTCCTCATACATCGATGTGGATCTGGACTATTATTTTTGCCT
TGACTATTTTTGGGCTAAATTTAAGTTCCACACATATTTTTGCCGAATCAGAATTCTGGTTATCATTGGTTAAAGTCCTC
ACTGTCATTAGCTTTATTATTCTTGGACTATTGGCTATTTTCGGGATTATTCATTTTGAGGGACATGCCTCCGCACCACT
GTTTAGCAATCTGACCAGTCACGGCTGGTTTCCACAGGGTTTGATGCCAATTTTTGCAACAATGCTGATTGTAAATTTTG
CATTTTCTGGAACTGAACTAATTGGTGTGGCAGCAGGCGAAACCAAAGATCCTTCTATCAATGTACCAAAAGCCATCAAT
GCTGCCATCTGGCGTCTGCTGATCTTTTTCGTTGGAACCATTGTTGTTATAAGTGCTTTATTGCCCTATGATCAGACTGG
CCTCGGCGGTCATAACGTCAGTAATAGCCCGTTTGTAACTGTGTTTCAATATATTGGTATTCCCTATGCAGATCATATTA
TTCGCTTTGTGATTATTACCGCACTCCTGTCAGCAGCAAACTCTGGTTTGTATGCCGCATCACGCATGATGTGGTCTTTA
TCAAATCAACGCCAGCTTCCTTCTGTCTTTTCAAAGCTAACGGCCAGTGGCACCCCCATTATTGCCTTAGTGGTTACCAT
GTTTGGCGCAATTCCTGGCTTACTCTCGGAGCAATTTGCACCTGAAACGATTTTTAAGAATCTTTTGGGCGTGGCTGCAT
TTACCATGGTGATTGTATGGATGAGCATCTGCTTAAGTCAGTTTAATTTCAGACGGCACTGGTATAAACAAGGCTATCAC
GCCAAAGACTTAAAATTCGCAGCTCCCCTGTTTCCAATTTTACCCATTTTAGGCTTCTTGTTTTGTTTGATTACTGGACT
AAGTATGGCGAAAGATCCAGAAATGTTGCCTGGTTTTATTGGATGCTTAATTTTTGTAGCGTGTTGCTATTTGAGCCACT
ACATATTTTATCGGGAAAAAAGCAAGCTGTGA

Upstream 100 bases:

>100_bases
AGTGTTCTCAGATTGCACATTTTGGTTTTTTCTCTAAAATAGCGCTCTTCTTTCATCTTGATGTGTTTTGTCTATGCCGC
CAGAATCCACAGATACAAAA

Downstream 100 bases:

>100_bases
TAGATACACACAAGAACCTCGGAAAAGTGTAGCAAAATCGCTACACTTTTCTTTGAATAACACTGGTTTAAATGCCGAAT
CACCTGTAAATTTTGAATTA

Product: S-methylmethionine APC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MLDSAAPLKRAMSTRHLVMLSLGGAIGTGLFLGSGEVITQTGPIGAVIAYMLGGLIAYMVMLCLGELAVHMPVSGSFGAY
AKKYIGPGTGYMISWVYWLTWTATLGTEFTAAALLMQEWFPHTSMWIWTIIFALTIFGLNLSSTHIFAESEFWLSLVKVL
TVISFIILGLLAIFGIIHFEGHASAPLFSNLTSHGWFPQGLMPIFATMLIVNFAFSGTELIGVAAGETKDPSINVPKAIN
AAIWRLLIFFVGTIVVISALLPYDQTGLGGHNVSNSPFVTVFQYIGIPYADHIIRFVIITALLSAANSGLYAASRMMWSL
SNQRQLPSVFSKLTASGTPIIALVVTMFGAIPGLLSEQFAPETIFKNLLGVAAFTMVIVWMSICLSQFNFRRHWYKQGYH
AKDLKFAAPLFPILPILGFLFCLITGLSMAKDPEMLPGFIGCLIFVACCYLSHYIFYREKSKL

Sequences:

>Translated_463_residues
MLDSAAPLKRAMSTRHLVMLSLGGAIGTGLFLGSGEVITQTGPIGAVIAYMLGGLIAYMVMLCLGELAVHMPVSGSFGAY
AKKYIGPGTGYMISWVYWLTWTATLGTEFTAAALLMQEWFPHTSMWIWTIIFALTIFGLNLSSTHIFAESEFWLSLVKVL
TVISFIILGLLAIFGIIHFEGHASAPLFSNLTSHGWFPQGLMPIFATMLIVNFAFSGTELIGVAAGETKDPSINVPKAIN
AAIWRLLIFFVGTIVVISALLPYDQTGLGGHNVSNSPFVTVFQYIGIPYADHIIRFVIITALLSAANSGLYAASRMMWSL
SNQRQLPSVFSKLTASGTPIIALVVTMFGAIPGLLSEQFAPETIFKNLLGVAAFTMVIVWMSICLSQFNFRRHWYKQGYH
AKDLKFAAPLFPILPILGFLFCLITGLSMAKDPEMLPGFIGCLIFVACCYLSHYIFYREKSKL
>Mature_463_residues
MLDSAAPLKRAMSTRHLVMLSLGGAIGTGLFLGSGEVITQTGPIGAVIAYMLGGLIAYMVMLCLGELAVHMPVSGSFGAY
AKKYIGPGTGYMISWVYWLTWTATLGTEFTAAALLMQEWFPHTSMWIWTIIFALTIFGLNLSSTHIFAESEFWLSLVKVL
TVISFIILGLLAIFGIIHFEGHASAPLFSNLTSHGWFPQGLMPIFATMLIVNFAFSGTELIGVAAGETKDPSINVPKAIN
AAIWRLLIFFVGTIVVISALLPYDQTGLGGHNVSNSPFVTVFQYIGIPYADHIIRFVIITALLSAANSGLYAASRMMWSL
SNQRQLPSVFSKLTASGTPIIALVVTMFGAIPGLLSEQFAPETIFKNLLGVAAFTMVIVWMSICLSQFNFRRHWYKQGYH
AKDLKFAAPLFPILPILGFLFCLITGLSMAKDPEMLPGFIGCLIFVACCYLSHYIFYREKSKL

Specific function: Transporter For The Intake Of S-Methylmethionine. [C]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI114326544, Length=380, Percent_Identity=25.2631578947368, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI114326550, Length=380, Percent_Identity=25.2631578947368, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI258614003, Length=396, Percent_Identity=20.7070707070707, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI258614005, Length=396, Percent_Identity=20.7070707070707, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI4507047, Length=388, Percent_Identity=20.360824742268, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI258645169, Length=395, Percent_Identity=20, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI181337167, Length=360, Percent_Identity=22.5, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081708, Length=460, Percent_Identity=51.9565217391304, Blast_Score=494, Evalue=1e-141,
Organism=Escherichia coli, GI1788480, Length=427, Percent_Identity=42.6229508196721, Blast_Score=347, Evalue=7e-97,
Organism=Escherichia coli, GI1786789, Length=414, Percent_Identity=36.4734299516908, Blast_Score=268, Evalue=8e-73,
Organism=Escherichia coli, GI48994972, Length=443, Percent_Identity=35.4401805869075, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1786302, Length=419, Percent_Identity=35.3221957040573, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI87081915, Length=407, Percent_Identity=36.1179361179361, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1786602, Length=423, Percent_Identity=38.2978723404255, Blast_Score=254, Evalue=9e-69,
Organism=Escherichia coli, GI1789017, Length=420, Percent_Identity=34.7619047619048, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI1790653, Length=410, Percent_Identity=33.6585365853659, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI87081869, Length=175, Percent_Identity=27.4285714285714, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=455, Percent_Identity=22.6373626373626, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320772, Length=420, Percent_Identity=32.3809523809524, Blast_Score=228, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6324553, Length=413, Percent_Identity=32.2033898305085, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6324061, Length=476, Percent_Identity=29.4117647058824, Blast_Score=211, Evalue=1e-55,
Organism=Saccharomyces cerevisiae, GI6322892, Length=420, Percent_Identity=33.0952380952381, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6319824, Length=411, Percent_Identity=29.683698296837, Blast_Score=199, Evalue=9e-52,
Organism=Saccharomyces cerevisiae, GI6320717, Length=398, Percent_Identity=30.1507537688442, Blast_Score=196, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6324990, Length=442, Percent_Identity=27.3755656108597, Blast_Score=192, Evalue=7e-50,
Organism=Saccharomyces cerevisiae, GI6322967, Length=423, Percent_Identity=29.7872340425532, Blast_Score=189, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6321629, Length=484, Percent_Identity=27.8925619834711, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6319543, Length=407, Percent_Identity=28.992628992629, Blast_Score=186, Evalue=6e-48,
Organism=Saccharomyces cerevisiae, GI6324924, Length=420, Percent_Identity=27.1428571428571, Blast_Score=180, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6324059, Length=420, Percent_Identity=28.8095238095238, Blast_Score=179, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6321053, Length=416, Percent_Identity=26.2019230769231, Blast_Score=179, Evalue=7e-46,
Organism=Saccharomyces cerevisiae, GI6319542, Length=415, Percent_Identity=28.433734939759, Blast_Score=178, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6320251, Length=416, Percent_Identity=27.6442307692308, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6324981, Length=447, Percent_Identity=29.7539149888143, Blast_Score=173, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6319608, Length=433, Percent_Identity=22.6327944572748, Blast_Score=130, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6320364, Length=494, Percent_Identity=25.5060728744939, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24667468, Length=374, Percent_Identity=21.3903743315508, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50630; Mature: 50630

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDSAAPLKRAMSTRHLVMLSLGGAIGTGLFLGSGEVITQTGPIGAVIAYMLGGLIAYMV
CCCCCHHHHHHHHHHHHHHHHHCCHHHHCEEECCCCEEEECCCHHHHHHHHHHHHHHHHH
MLCLGELAVHMPVSGSFGAYAKKYIGPGTGYMISWVYWLTWTATLGTEFTAAALLMQEWF
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
PHTSMWIWTIIFALTIFGLNLSSTHIFAESEFWLSLVKVLTVISFIILGLLAIFGIIHFE
CCCHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GHASAPLFSNLTSHGWFPQGLMPIFATMLIVNFAFSGTELIGVAAGETKDPSINVPKAIN
CCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHH
AAIWRLLIFFVGTIVVISALLPYDQTGLGGHNVSNSPFVTVFQYIGIPYADHIIRFVIIT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
ALLSAANSGLYAASRMMWSLSNQRQLPSVFSKLTASGTPIIALVVTMFGAIPGLLSEQFA
HHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
PETIFKNLLGVAAFTMVIVWMSICLSQFNFRRHWYKQGYHAKDLKFAAPLFPILPILGFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
FCLITGLSMAKDPEMLPGFIGCLIFVACCYLSHYIFYREKSKL
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDSAAPLKRAMSTRHLVMLSLGGAIGTGLFLGSGEVITQTGPIGAVIAYMLGGLIAYMV
CCCCCHHHHHHHHHHHHHHHHHCCHHHHCEEECCCCEEEECCCHHHHHHHHHHHHHHHHH
MLCLGELAVHMPVSGSFGAYAKKYIGPGTGYMISWVYWLTWTATLGTEFTAAALLMQEWF
HHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
PHTSMWIWTIIFALTIFGLNLSSTHIFAESEFWLSLVKVLTVISFIILGLLAIFGIIHFE
CCCHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GHASAPLFSNLTSHGWFPQGLMPIFATMLIVNFAFSGTELIGVAAGETKDPSINVPKAIN
CCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHH
AAIWRLLIFFVGTIVVISALLPYDQTGLGGHNVSNSPFVTVFQYIGIPYADHIIRFVIIT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
ALLSAANSGLYAASRMMWSLSNQRQLPSVFSKLTASGTPIIALVVTMFGAIPGLLSEQFA
HHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
PETIFKNLLGVAAFTMVIVWMSICLSQFNFRRHWYKQGYHAKDLKFAAPLFPILPILGFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
FCLITGLSMAKDPEMLPGFIGCLIFVACCYLSHYIFYREKSKL
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]