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The map label for this gene is fecD [C]

Identifier: 50084175

GI number: 50084175

Start: 957037

End: 958053

Strand: Reverse

Name: fecD [C]

Synonym: ACIAD0970

Alternate gene names: 50084175

Gene position: 958053-957037 (Counterclockwise)

Preceding gene: 50084176

Following gene: 50084174

Centisome position: 26.62

GC content: 42.28

Gene sequence:

>1017_bases
GTGAAACGTTCGTTTTTATTTTTAATTTATTTTATTCCTTTGCCACTGATTATTTTGTCATTATTGATTGGTCCCTCTGA
ACAGTTTGGTATGACTGATTTTGCTTATGCACTCTGGGCATTTGTCGTTCCTCCTCTACACTTGAATGAATTGGATATGC
AGCGTCTAGAACTAATGCAAAATATCATCATCAATGTGCGTATGCCGCGTGTGTTTTTAACGTTCATGGTGGGTGCAGCT
CTGGCATCTTCGGGCAATACCTTACAAGCGCTGTTTCGTAACCCTTTAGTCGATTCTTATGTCTTGGGTATTTCCTCTGG
CGCTGCGCTGGGTGCTGCATTGGCACTTCTAACCAATTGGATGCCCGTACAACTCTCTGCATTTATTTTTGGAATTTTAG
CGGTCTGCATGACTTATGGTTTTGCACAGCAGCGCTATGAAAAAAGTTCGGTTGTGGTGATTTTACTTTCGGGAATGATC
GTATCAGGATTATTTATTGCTGGCCTGAGTATTGTGCAATATTTAAGTGATCCCTATAAATTACAAGCCATTGTGCAATG
GACGATGGGCAATTTACATCAAGCAACCTGGGACAAAGTACAACAGGCCTTTTTACCCATTAGCTTATCACTGATTGGAA
TCTATTGTTTACGTTGGCGACTCAATTTACTGGCATTGGGTCATCTTGAAGCACAGGCAGTGGGTGTGGATCCGCGTCGT
GACCAGTTTTTACTGATTTTGTGTGTCACGCTGGCGACTTCATCTTCAGTCGCAGTGGCTGGAATCATTAGTCTCTATGG
TTTATTCCTACCACATTTGGTGCGCATGATGATTGGGCCAGACAATGCGAAAACAGTACCCGCCAATATTTTTCTGGGTG
GTTCTTTTTTACTACTGATTGATAATTTCTCCCGAACATTTTCGACCTTTGAAATTCCAATCGGGATTTTTACCATGCTG
CTAGGCGCACCGCTATTTTTGTATTTGATCCGCCGTTATCGAATGAACTGGGCTTGA

Upstream 100 bases:

>100_bases
TGCAACCCAGGACAAACTCAGAATCCTGACCCAGTTTTATGGCAAAACAGCGGCAGAACAGCTCATTCAATATGCCAACG
ATGTGACCAAGGAATAATCT

Downstream 100 bases:

>100_bases
GTTATGAGTAAGATCACGCTTCAAAATATCCACTTTGCCTATCAGCAAAAAACGGTATTAAAAAATATTCATCTTGAGTT
TCGATCCAACCGTTTTTCGG

Product: iron ABC transporter

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKRSFLFLIYFIPLPLIILSLLIGPSEQFGMTDFAYALWAFVVPPLHLNELDMQRLELMQNIIINVRMPRVFLTFMVGAA
LASSGNTLQALFRNPLVDSYVLGISSGAALGAALALLTNWMPVQLSAFIFGILAVCMTYGFAQQRYEKSSVVVILLSGMI
VSGLFIAGLSIVQYLSDPYKLQAIVQWTMGNLHQATWDKVQQAFLPISLSLIGIYCLRWRLNLLALGHLEAQAVGVDPRR
DQFLLILCVTLATSSSVAVAGIISLYGLFLPHLVRMMIGPDNAKTVPANIFLGGSFLLLIDNFSRTFSTFEIPIGIFTML
LGAPLFLYLIRRYRMNWA

Sequences:

>Translated_338_residues
MKRSFLFLIYFIPLPLIILSLLIGPSEQFGMTDFAYALWAFVVPPLHLNELDMQRLELMQNIIINVRMPRVFLTFMVGAA
LASSGNTLQALFRNPLVDSYVLGISSGAALGAALALLTNWMPVQLSAFIFGILAVCMTYGFAQQRYEKSSVVVILLSGMI
VSGLFIAGLSIVQYLSDPYKLQAIVQWTMGNLHQATWDKVQQAFLPISLSLIGIYCLRWRLNLLALGHLEAQAVGVDPRR
DQFLLILCVTLATSSSVAVAGIISLYGLFLPHLVRMMIGPDNAKTVPANIFLGGSFLLLIDNFSRTFSTFEIPIGIFTML
LGAPLFLYLIRRYRMNWA
>Mature_338_residues
MKRSFLFLIYFIPLPLIILSLLIGPSEQFGMTDFAYALWAFVVPPLHLNELDMQRLELMQNIIINVRMPRVFLTFMVGAA
LASSGNTLQALFRNPLVDSYVLGISSGAALGAALALLTNWMPVQLSAFIFGILAVCMTYGFAQQRYEKSSVVVILLSGMI
VSGLFIAGLSIVQYLSDPYKLQAIVQWTMGNLHQATWDKVQQAFLPISLSLIGIYCLRWRLNLLALGHLEAQAVGVDPRR
DQFLLILCVTLATSSSVAVAGIISLYGLFLPHLVRMMIGPDNAKTVPANIFLGGSFLLLIDNFSRTFSTFEIPIGIFTML
LGAPLFLYLIRRYRMNWA

Specific function: Part of a binding-protein-dependent transport system for an iron chelatin; probably responsible for the translocation of the substrate across the membrane (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=296, Percent_Identity=31.4189189189189, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790741, Length=287, Percent_Identity=29.9651567944251, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788004, Length=279, Percent_Identity=32.258064516129, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786347, Length=278, Percent_Identity=30.2158273381295, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786805, Length=283, Percent_Identity=27.9151943462898, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786804, Length=283, Percent_Identity=28.2685512367491, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37552; Mature: 37552

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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ECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure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ECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]