Click here to switch to the map view.

The map label for this gene is 50084168

Identifier: 50084168

GI number: 50084168

Start: 949007

End: 950524

Strand: Reverse

Name: 50084168

Synonym: ACIAD0963

Alternate gene names: NA

Gene position: 950524-949007 (Counterclockwise)

Preceding gene: 50084169

Following gene: 50084167

Centisome position: 26.41

GC content: 41.9

Gene sequence:

>1518_bases
ATGAGTTTCAGAATTAATCCACTCAATGCCATCGATTTTTACAAAGCAGATCACAGACGTCAGTATCCTGAAGGTACAGA
ATATGTGTACGCCAACTTTACGCCCCGCTCTTCACGTCTGGCCAATATGCTGCATGATTTTGATGACAAAATTGTATTCT
TTGGCTTACAGGGATTTATTCAGCATTTTCTGATTGAAACATGGAATGAAGGCTTTTTTAATCAAGATAAAGCGACGGTG
GTGAGTCACTATAAACGTAGAATGGATACATCTTTGGGAGAAGGTGCTGTATCTGTTGAACATATTGAAGCCTTGCATGA
TCTAGGTTATCTGCCACTCAAAATCAAGGCACTGCCAGAAGGAAGTCGCGTAAATATGCGGGTTCCTGTGCTCACTGTCA
TCAATACTCAAGCAGAATTTTTCTGGCTCACCAACTATATCGAAACCGTGCTCAGTGCTGAACTCTGGAAAAGCTCAACC
ACAGCCACTATTGCATTTGAATACAAGCGTTTATTAACTCAATATGCCGTAAAAACAGGCGCTTCAATTGAAAATGTAGT
TGTACAAGGACATGACTTCAGTAGCCGTGGAATGAGTGGTATTTATGATGCAGCCCAATCTGGTGTCGGCCATTTAACCA
GTTTTATTGGAACCGATGCGGTAACAGCAATTGATTATGCAGAACAATACTATGCAGCTTCTGGTGTAGTGGGTGTTTCT
GTACCCGCAACTGAGCACAGTGTTATGTGTATGGGAAGCGAAGAAAATGAGCTTGAGACATTTCGTAGGCTTATCTGTGA
GCTTTACCCTTCAGGGATCGTGAGTATCGTATCTGACACTTGGGATTTCTGGCGAGTACTGAGCGAATTTAGCGTTAAGC
TGAAACAGGATATTTTAAACCGCACACCTAATGCATTAGGGCTGGCAAAAGTAGTTTTCCGACCTGATTCAGGTGATCCA
GTTAAAATCATTTGTGGTGATCCTGACGCAGAAAAGGATACTCCTGCATATAAAGGTGCTGTTCAATTGCTCTGGGAAAT
TTTTGGTGGAACCTATACTGCTCAAGGTTATAAAGTGTTGCATGAGCGTGTCGGGCTCATTTACGGAGACTCAATTACCC
TACAACGTGCTGAAGCAATTTTACAAGGTCTTGAAGCCCAAGGCTTTGCATCTAGCAATCTAGTATTTGGAATTGGTAGC
TATACCTATAACTATATGACACGCGATACATTCGGTTTTGCAGTTAAAGCAACCTGGGGACAGGTCAATGGTGTTGGACG
TGAACTTTTCAAAGACCCTGTTACCGATAGCGGTACCAAAAAATCGGCTCAAGGATTATTGCGCGTTGAAAGATCACAAG
ATGGTTTTACACTTTTTGATCGGCAAAGTAAGCAACAGGAAAATCAGGGAGAGTTACATACCGTCTTTGAAAATGGGCAG
TTATGCTTAAAAAGCACACTGGATGAAATCAGACAACGTCTTGCTCAGCAACTTGAGTCCTTTAAAGACTCAAATTAA

Upstream 100 bases:

>100_bases
CTGATCGACCAGATATTTACCAGCAATAGTCGACCACAACAATTCCATAAAAACCTGAATGTAATTGAATTTACAGCAAT
TTAAATATTGGAGAAACATT

Downstream 100 bases:

>100_bases
TAATTCAATTTAATTAAGCGAATCTCATCACCCAATTAAGGATTTTTACTTGGATAATTCGAGTGAGACTGTAATAATCT
CCGAATTATCCATCCTTTTT

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MSFRINPLNAIDFYKADHRRQYPEGTEYVYANFTPRSSRLANMLHDFDDKIVFFGLQGFIQHFLIETWNEGFFNQDKATV
VSHYKRRMDTSLGEGAVSVEHIEALHDLGYLPLKIKALPEGSRVNMRVPVLTVINTQAEFFWLTNYIETVLSAELWKSST
TATIAFEYKRLLTQYAVKTGASIENVVVQGHDFSSRGMSGIYDAAQSGVGHLTSFIGTDAVTAIDYAEQYYAASGVVGVS
VPATEHSVMCMGSEENELETFRRLICELYPSGIVSIVSDTWDFWRVLSEFSVKLKQDILNRTPNALGLAKVVFRPDSGDP
VKIICGDPDAEKDTPAYKGAVQLLWEIFGGTYTAQGYKVLHERVGLIYGDSITLQRAEAILQGLEAQGFASSNLVFGIGS
YTYNYMTRDTFGFAVKATWGQVNGVGRELFKDPVTDSGTKKSAQGLLRVERSQDGFTLFDRQSKQQENQGELHTVFENGQ
LCLKSTLDEIRQRLAQQLESFKDSN

Sequences:

>Translated_505_residues
MSFRINPLNAIDFYKADHRRQYPEGTEYVYANFTPRSSRLANMLHDFDDKIVFFGLQGFIQHFLIETWNEGFFNQDKATV
VSHYKRRMDTSLGEGAVSVEHIEALHDLGYLPLKIKALPEGSRVNMRVPVLTVINTQAEFFWLTNYIETVLSAELWKSST
TATIAFEYKRLLTQYAVKTGASIENVVVQGHDFSSRGMSGIYDAAQSGVGHLTSFIGTDAVTAIDYAEQYYAASGVVGVS
VPATEHSVMCMGSEENELETFRRLICELYPSGIVSIVSDTWDFWRVLSEFSVKLKQDILNRTPNALGLAKVVFRPDSGDP
VKIICGDPDAEKDTPAYKGAVQLLWEIFGGTYTAQGYKVLHERVGLIYGDSITLQRAEAILQGLEAQGFASSNLVFGIGS
YTYNYMTRDTFGFAVKATWGQVNGVGRELFKDPVTDSGTKKSAQGLLRVERSQDGFTLFDRQSKQQENQGELHTVFENGQ
LCLKSTLDEIRQRLAQQLESFKDSN
>Mature_504_residues
SFRINPLNAIDFYKADHRRQYPEGTEYVYANFTPRSSRLANMLHDFDDKIVFFGLQGFIQHFLIETWNEGFFNQDKATVV
SHYKRRMDTSLGEGAVSVEHIEALHDLGYLPLKIKALPEGSRVNMRVPVLTVINTQAEFFWLTNYIETVLSAELWKSSTT
ATIAFEYKRLLTQYAVKTGASIENVVVQGHDFSSRGMSGIYDAAQSGVGHLTSFIGTDAVTAIDYAEQYYAASGVVGVSV
PATEHSVMCMGSEENELETFRRLICELYPSGIVSIVSDTWDFWRVLSEFSVKLKQDILNRTPNALGLAKVVFRPDSGDPV
KIICGDPDAEKDTPAYKGAVQLLWEIFGGTYTAQGYKVLHERVGLIYGDSITLQRAEAILQGLEAQGFASSNLVFGIGSY
TYNYMTRDTFGFAVKATWGQVNGVGRELFKDPVTDSGTKKSAQGLLRVERSQDGFTLFDRQSKQQENQGELHTVFENGQL
CLKSTLDEIRQRLAQQLESFKDSN

Specific function: Unknown

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Homo sapiens, GI5031977, Length=502, Percent_Identity=30.4780876494024, Blast_Score=207, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015977
- InterPro:   IPR016471
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: NA

Molecular weight: Translated: 56527; Mature: 56396

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFRINPLNAIDFYKADHRRQYPEGTEYVYANFTPRSSRLANMLHDFDDKIVFFGLQGFI
CCEECCCCCHHHHHCCHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEHHHHH
QHFLIETWNEGFFNQDKATVVSHYKRRMDTSLGEGAVSVEHIEALHDLGYLPLKIKALPE
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCC
GSRVNMRVPVLTVINTQAEFFWLTNYIETVLSAELWKSSTTATIAFEYKRLLTQYAVKTG
CCEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCC
ASIENVVVQGHDFSSRGMSGIYDAAQSGVGHLTSFIGTDAVTAIDYAEQYYAASGVVGVS
CCHHHEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEE
VPATEHSVMCMGSEENELETFRRLICELYPSGIVSIVSDTWDFWRVLSEFSVKLKQDILN
CCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTPNALGLAKVVFRPDSGDPVKIICGDPDAEKDTPAYKGAVQLLWEIFGGTYTAQGYKVL
CCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEECHHHHHH
HERVGLIYGDSITLQRAEAILQGLEAQGFASSNLVFGIGSYTYNYMTRDTFGFAVKATWG
HHHHCEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEECCCCCEEEEECCC
QVNGVGRELFKDPVTDSGTKKSAQGLLRVERSQDGFTLFDRQSKQQENQGELHTVFENGQ
CCCHHHHHHHHCCCCCCCCCHHHHHHHEEECCCCCCEEECCHHHCCCCCCCEEEEEECCC
LCLKSTLDEIRQRLAQQLESFKDSN
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SFRINPLNAIDFYKADHRRQYPEGTEYVYANFTPRSSRLANMLHDFDDKIVFFGLQGFI
CEECCCCCHHHHHCCHHHCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEHHHHH
QHFLIETWNEGFFNQDKATVVSHYKRRMDTSLGEGAVSVEHIEALHDLGYLPLKIKALPE
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCC
GSRVNMRVPVLTVINTQAEFFWLTNYIETVLSAELWKSSTTATIAFEYKRLLTQYAVKTG
CCEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHCC
ASIENVVVQGHDFSSRGMSGIYDAAQSGVGHLTSFIGTDAVTAIDYAEQYYAASGVVGVS
CCHHHEEEECCCCCCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEE
VPATEHSVMCMGSEENELETFRRLICELYPSGIVSIVSDTWDFWRVLSEFSVKLKQDILN
CCCCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTPNALGLAKVVFRPDSGDPVKIICGDPDAEKDTPAYKGAVQLLWEIFGGTYTAQGYKVL
CCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEECHHHHHH
HERVGLIYGDSITLQRAEAILQGLEAQGFASSNLVFGIGSYTYNYMTRDTFGFAVKATWG
HHHHCEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEECCCCCEEEEECCC
QVNGVGRELFKDPVTDSGTKKSAQGLLRVERSQDGFTLFDRQSKQQENQGELHTVFENGQ
CCCHHHHHHHHCCCCCCCCCHHHHHHHEEECCCCCCEEECCHHHCCCCCCCEEEEEECCC
LCLKSTLDEIRQRLAQQLESFKDSN
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]