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The map label for this gene is bioC [H]

Identifier: 50084070

GI number: 50084070

Start: 845597

End: 846364

Strand: Direct

Name: bioC [H]

Synonym: ACIAD0858

Alternate gene names: 50084070

Gene position: 845597-846364 (Clockwise)

Preceding gene: 50084069

Following gene: 50084071

Centisome position: 23.5

GC content: 39.71

Gene sequence:

>768_bases
TTGTTTGTGAATCTGAATAAATCACTCATTGCTCAGCGTTTTGCGAAGGCGCGACAAAGTTATGTAGAAAATGCCATTGC
GCAGAAAAAAATCAGTCATCATTTGTGCCATTTGATGCAAGCTTATTGTCCGTTACATCTAAGCCGTATATTTGAAATCG
GCTGTGGCTCGGGCAATTTGACACAGGAATTATTTGTATCTTTTCAGATTCAGAGAGCATATTTGAATGATCTATACGAT
GAAGTCAAACAGCATTTTTTAGATGAGCAGCCAATCGAGTGGTGTATCGGGGACATTGAAAGTTTAAGTTTGCCAGAGCA
TTTAAATGCAATTGTTTCAAGCTCTGCCATTCAATGGGTTCAAAACTTACCTCAGCTTTTAGGTCGCTGTCATCATGCCT
TGAATGATCAAGGCTGGCTATGTCTTTCAACTTTCGGCTCTGATAATTTTAAAGAAATTAAACAACTGACAGGTCAAGGG
CTGAGCTATTGGTCTGTGCAGGATTGGCAAGTTCATTTACAAGCTTCTGGTTTTGAGCTGATGAAGATTGAACAACAGCA
ACTTAAGATGCAATTTGATTCGCCCAGAGCAATCCTCAAACATCTTAAGGCAACTGGTGTCACAGGGACAGTGGCTACTA
CGCAACCTCACTGGAATAAACAATCTTTAGCACAGTTCTATCATGATTATTGTCAGTTTCAGACAGATGATGGTCATTAT
GAACTGACCTATCATCCTATTTATATCATTGCTCGGAGAACGTCATGA

Upstream 100 bases:

>100_bases
CAATGCCCGTTCGTCCACCGACAGTGCCACAGCATAGCGCTCGTTTAAGAATTTCATTAACATCACTCATTCAAATAGAT
GAACTAGATCGGTTGGTGGC

Downstream 100 bases:

>100_bases
CGGCTTCTGTTTATTTTATTAGTGGCATTGATACAGGTATTGGAAAAACTTATGCCACGGGATATCTTGCAAAGCAATGG
ATTGATCAGGGTATAAAAAC

Product: biotin biosynthesis protein (BioC)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MFVNLNKSLIAQRFAKARQSYVENAIAQKKISHHLCHLMQAYCPLHLSRIFEIGCGSGNLTQELFVSFQIQRAYLNDLYD
EVKQHFLDEQPIEWCIGDIESLSLPEHLNAIVSSSAIQWVQNLPQLLGRCHHALNDQGWLCLSTFGSDNFKEIKQLTGQG
LSYWSVQDWQVHLQASGFELMKIEQQQLKMQFDSPRAILKHLKATGVTGTVATTQPHWNKQSLAQFYHDYCQFQTDDGHY
ELTYHPIYIIARRTS

Sequences:

>Translated_255_residues
MFVNLNKSLIAQRFAKARQSYVENAIAQKKISHHLCHLMQAYCPLHLSRIFEIGCGSGNLTQELFVSFQIQRAYLNDLYD
EVKQHFLDEQPIEWCIGDIESLSLPEHLNAIVSSSAIQWVQNLPQLLGRCHHALNDQGWLCLSTFGSDNFKEIKQLTGQG
LSYWSVQDWQVHLQASGFELMKIEQQQLKMQFDSPRAILKHLKATGVTGTVATTQPHWNKQSLAQFYHDYCQFQTDDGHY
ELTYHPIYIIARRTS
>Mature_255_residues
MFVNLNKSLIAQRFAKARQSYVENAIAQKKISHHLCHLMQAYCPLHLSRIFEIGCGSGNLTQELFVSFQIQRAYLNDLYD
EVKQHFLDEQPIEWCIGDIESLSLPEHLNAIVSSSAIQWVQNLPQLLGRCHHALNDQGWLCLSTFGSDNFKEIKQLTGQG
LSYWSVQDWQVHLQASGFELMKIEQQQLKMQFDSPRAILKHLKATGVTGTVATTQPHWNKQSLAQFYHDYCQFQTDDGHY
ELTYHPIYIIARRTS

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 29426; Mature: 29426

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVNLNKSLIAQRFAKARQSYVENAIAQKKISHHLCHLMQAYCPLHLSRIFEIGCGSGNL
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TQELFVSFQIQRAYLNDLYDEVKQHFLDEQPIEWCIGDIESLSLPEHLNAIVSSSAIQWV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHCCCHHHHHHHHHHHHHHHH
QNLPQLLGRCHHALNDQGWLCLSTFGSDNFKEIKQLTGQGLSYWSVQDWQVHLQASGFEL
HHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECEEEEEEECCCHH
MKIEQQQLKMQFDSPRAILKHLKATGVTGTVATTQPHWNKQSLAQFYHDYCQFQTDDGHY
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCE
ELTYHPIYIIARRTS
EEEEEEEEEEEEECC
>Mature Secondary Structure
MFVNLNKSLIAQRFAKARQSYVENAIAQKKISHHLCHLMQAYCPLHLSRIFEIGCGSGNL
CEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
TQELFVSFQIQRAYLNDLYDEVKQHFLDEQPIEWCIGDIESLSLPEHLNAIVSSSAIQWV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHCCCHHHHHHHHHHHHHHHH
QNLPQLLGRCHHALNDQGWLCLSTFGSDNFKEIKQLTGQGLSYWSVQDWQVHLQASGFEL
HHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECEEEEEEECCCHH
MKIEQQQLKMQFDSPRAILKHLKATGVTGTVATTQPHWNKQSLAQFYHDYCQFQTDDGHY
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCE
ELTYHPIYIIARRTS
EEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]