Click here to switch to the map view.

The map label for this gene is gltS [H]

Identifier: 50084018

GI number: 50084018

Start: 796487

End: 797722

Strand: Direct

Name: gltS [H]

Synonym: ACIAD0804

Alternate gene names: 50084018

Gene position: 796487-797722 (Clockwise)

Preceding gene: 50084016

Following gene: 50084019

Centisome position: 22.13

GC content: 41.59

Gene sequence:

>1236_bases
ATGGAATTTACATTTAATGCCTTCTATACGTTGATTGCAGCGGTCATCGTATTACTTTTAGGGCGATTTTTAGTCAATAA
AATTGACTTTCTGAGACGTTATAATATCCCTGAACCTGTTGCTGGTGGTCTCGTCGCAGCAACAGTTTCGTTTGCTGTAC
ACTCGATTTGGGGGTATAGCATTATTTTTAGCAGTGAACTACAAACCAGTTTTATGTTAATTTTCTTTGCCTCGATCGGT
TTGAGTGCGCATTTTGCCAAACTCAAAGAAGGTGGGGTGGGATTAATCATATTCTTGATTTGTGTTGCGTCATTTATTGT
TGTCCAAGATATTGTCGGAATAAGTCTGGCCACTCTATTAGGTATCGACCCGCTGATCGGTTTGATTGCTGGTTCAATTA
CACTCACTGGAGGGCATGGCACAGCAGGTGCATGGGGAGAAATCTTAGAAACTCAACATGGCATTCAGGGGGCGCTAGCA
CTTGGTATGGCGAGTGCAACTTTTGGACTGATTATTGGTGGAATTATTGGGGGACCTTTAGCCAAGCTATTGATTAATCG
TCATCAGCTCGCAAATGCCAAAACACGTGCCCAAATTAAAGACCGCGATACGCATGTTGATACGCATCCAGATGATCTGG
CACCATTTGAAAATCCACATCAGGTTCGATTAATTACCGCAGATAATGCCATTACTACGTTGGGAATGTTCGCTGCCTGT
CTGGCCTTTGCTGACTTCATGACTGGATATAGCAAAGGAACATGGTTCGAGTTACCTACTTTTGTATGGGCACTTGGTGG
TGGCGTGATCTTAAGAAATGTTCTGGAAAGTATTTTTCGTGTCGATATTTTTGATCGTGCGATTGATGTTTTTGGAAATG
CATCACTTTCACTGTATTTGGCGATGGCTTTATTATCGTTAAAATTGTGGCAATTGGTCGATCTTGCTGGTCCTTTAGTA
ATTATCCTTGCAGCACAAACCTTAACAATGGCATTATACGCCGCCTTTGTGACGTTTAAGGTCATGGGTAAAAATTACGA
TGCAGCTGTACTTGCCGCTGGACATTGTGGTTTTGGTATGGGCGCAACGCCTACTGCCGTTGCAAATATGCAAGCAATTA
CGAATATGTATGGCCCGTCGCATAAAGCATTTTTAATTGTTCCACTGTGTGGTGCATTTTTTGTTGATTTAATTAATGCG
ACCGTTATTCAAGTTATTCTTAAGTTTTTTGTGTAA

Upstream 100 bases:

>100_bases
TTTGGGTAATTCTTCTCAAGATTCCGTTTAGTCATCTTTATCATTCACATGTTAGAAGAATGAAAATCGATTAAATGCTT
GAGAGTTAAATGGAAAATAT

Downstream 100 bases:

>100_bases
GACTAAAAAACTGATTGAAAGATAAACTGATTCGCAATGTCGATAAGTAAAAAAGTCTCTAGTCACAGAGGCTTTTTTAT
TTGTTAAATAGATTTAGATA

Product: sodium/glutamate symport carrier protein

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MEFTFNAFYTLIAAVIVLLLGRFLVNKIDFLRRYNIPEPVAGGLVAATVSFAVHSIWGYSIIFSSELQTSFMLIFFASIG
LSAHFAKLKEGGVGLIIFLICVASFIVVQDIVGISLATLLGIDPLIGLIAGSITLTGGHGTAGAWGEILETQHGIQGALA
LGMASATFGLIIGGIIGGPLAKLLINRHQLANAKTRAQIKDRDTHVDTHPDDLAPFENPHQVRLITADNAITTLGMFAAC
LAFADFMTGYSKGTWFELPTFVWALGGGVILRNVLESIFRVDIFDRAIDVFGNASLSLYLAMALLSLKLWQLVDLAGPLV
IILAAQTLTMALYAAFVTFKVMGKNYDAAVLAAGHCGFGMGATPTAVANMQAITNMYGPSHKAFLIVPLCGAFFVDLINA
TVIQVILKFFV

Sequences:

>Translated_411_residues
MEFTFNAFYTLIAAVIVLLLGRFLVNKIDFLRRYNIPEPVAGGLVAATVSFAVHSIWGYSIIFSSELQTSFMLIFFASIG
LSAHFAKLKEGGVGLIIFLICVASFIVVQDIVGISLATLLGIDPLIGLIAGSITLTGGHGTAGAWGEILETQHGIQGALA
LGMASATFGLIIGGIIGGPLAKLLINRHQLANAKTRAQIKDRDTHVDTHPDDLAPFENPHQVRLITADNAITTLGMFAAC
LAFADFMTGYSKGTWFELPTFVWALGGGVILRNVLESIFRVDIFDRAIDVFGNASLSLYLAMALLSLKLWQLVDLAGPLV
IILAAQTLTMALYAAFVTFKVMGKNYDAAVLAAGHCGFGMGATPTAVANMQAITNMYGPSHKAFLIVPLCGAFFVDLINA
TVIQVILKFFV
>Mature_411_residues
MEFTFNAFYTLIAAVIVLLLGRFLVNKIDFLRRYNIPEPVAGGLVAATVSFAVHSIWGYSIIFSSELQTSFMLIFFASIG
LSAHFAKLKEGGVGLIIFLICVASFIVVQDIVGISLATLLGIDPLIGLIAGSITLTGGHGTAGAWGEILETQHGIQGALA
LGMASATFGLIIGGIIGGPLAKLLINRHQLANAKTRAQIKDRDTHVDTHPDDLAPFENPHQVRLITADNAITTLGMFAAC
LAFADFMTGYSKGTWFELPTFVWALGGGVILRNVLESIFRVDIFDRAIDVFGNASLSLYLAMALLSLKLWQLVDLAGPLV
IILAAQTLTMALYAAFVTFKVMGKNYDAAVLAAGHCGFGMGATPTAVANMQAITNMYGPSHKAFLIVPLCGAFFVDLINA
TVIQVILKFFV

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=387, Percent_Identity=51.421188630491, Blast_Score=340, Evalue=9e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 43878; Mature: 43878

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFTFNAFYTLIAAVIVLLLGRFLVNKIDFLRRYNIPEPVAGGLVAATVSFAVHSIWGYS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCHHHHHHHHHHHHHHHHHH
IIFSSELQTSFMLIFFASIGLSAHFAKLKEGGVGLIIFLICVASFIVVQDIVGISLATLL
EEEECHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIDPLIGLIAGSITLTGGHGTAGAWGEILETQHGIQGALALGMASATFGLIIGGIIGGPL
HHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AKLLINRHQLANAKTRAQIKDRDTHVDTHPDDLAPFENPHQVRLITADNAITTLGMFAAC
HHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHH
LAFADFMTGYSKGTWFELPTFVWALGGGVILRNVLESIFRVDIFDRAIDVFGNASLSLYL
HHHHHHHHCCCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AMALLSLKLWQLVDLAGPLVIILAAQTLTMALYAAFVTFKVMGKNYDAAVLAAGHCGFGM
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
GATPTAVANMQAITNMYGPSHKAFLIVPLCGAFFVDLINATVIQVILKFFV
CCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MEFTFNAFYTLIAAVIVLLLGRFLVNKIDFLRRYNIPEPVAGGLVAATVSFAVHSIWGYS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCHHHHHHHHHHHHHHHHHH
IIFSSELQTSFMLIFFASIGLSAHFAKLKEGGVGLIIFLICVASFIVVQDIVGISLATLL
EEEECHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIDPLIGLIAGSITLTGGHGTAGAWGEILETQHGIQGALALGMASATFGLIIGGIIGGPL
HHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AKLLINRHQLANAKTRAQIKDRDTHVDTHPDDLAPFENPHQVRLITADNAITTLGMFAAC
HHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHH
LAFADFMTGYSKGTWFELPTFVWALGGGVILRNVLESIFRVDIFDRAIDVFGNASLSLYL
HHHHHHHHCCCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AMALLSLKLWQLVDLAGPLVIILAAQTLTMALYAAFVTFKVMGKNYDAAVLAAGHCGFGM
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
GATPTAVANMQAITNMYGPSHKAFLIVPLCGAFFVDLINATVIQVILKFFV
CCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]