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The map label for this gene is nuoA

Identifier: 50083949

GI number: 50083949

Start: 714274

End: 714825

Strand: Direct

Name: nuoA

Synonym: ACIAD0730

Alternate gene names: 50083949

Gene position: 714274-714825 (Clockwise)

Preceding gene: 50083947

Following gene: 50083950

Centisome position: 19.85

GC content: 43.66

Gene sequence:

>552_bases
ATGAGTGCCATTACTCCATACGATTGGGCAATTATTGCCTTCGTGATCGGCGTTACATTTCTGTGCGTTTTTATGCTTAC
TGTTCCCTTACTCCTAGGGGGTAAATCATGGGGACGTGCGAAGCAGGAACAGTTTGAATCGGGTGTGGTGAGCGCAGGTG
GTGCTCGCATTCGTTTATCTGCAAAATTCTATTTGGTTGCAATTTTCTTTGTCGTGTTCGACCTTGAAGCACTTTATCTT
TATGCATGGGCAACATCTGTGCGTGAAGTCGGGTGGATGGGCTTTACCACGATGGTTATTTTTGTTGTAGATCTTCTTAT
TGCATTGATTTATGTCTTTGCAACAGGCGCCTTAACTTGGTCTCCGTCAGATCGTCGTAAAGCAGCAGGAATTAAACCTA
AAATCGGTTCTCCTAATATGAATATTGCAGAGATCACGCGATTCAATTCAATTGAAGAGTTGGTCATCGATCCAACTGGT
CATATCCCTGCACAATCCTCTGGTCGAATGAAATCCAAAACATCGACAGCACCGTCATCTAAACAGGAGTAA

Upstream 100 bases:

>100_bases
CAGGTACAATTGGCGGGATTAATTTTGTGTTTGGTGCGTTTCCAAGACCTAAACATACATTTCTTTGTTAAATAATAGGC
CTGCCAGGAGTTATCCCCGC

Downstream 100 bases:

>100_bases
CTCGGGATGAAATATACATTAACCCGTGCGAATCCGGATGCTAATCAATATCCATTACAAGAACGCCAAGTTGTGAACGA
TCCACTTCAGGAAGAAGTCA

Product: NADH dehydrogenase I chain A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSAITPYDWAIIAFVIGVTFLCVFMLTVPLLLGGKSWGRAKQEQFESGVVSAGGARIRLSAKFYLVAIFFVVFDLEALYL
YAWATSVREVGWMGFTTMVIFVVDLLIALIYVFATGALTWSPSDRRKAAGIKPKIGSPNMNIAEITRFNSIEELVIDPTG
HIPAQSSGRMKSKTSTAPSSKQE

Sequences:

>Translated_183_residues
MSAITPYDWAIIAFVIGVTFLCVFMLTVPLLLGGKSWGRAKQEQFESGVVSAGGARIRLSAKFYLVAIFFVVFDLEALYL
YAWATSVREVGWMGFTTMVIFVVDLLIALIYVFATGALTWSPSDRRKAAGIKPKIGSPNMNIAEITRFNSIEELVIDPTG
HIPAQSSGRMKSKTSTAPSSKQE
>Mature_182_residues
SAITPYDWAIIAFVIGVTFLCVFMLTVPLLLGGKSWGRAKQEQFESGVVSAGGARIRLSAKFYLVAIFFVVFDLEALYLY
AWATSVREVGWMGFTTMVIFVVDLLIALIYVFATGALTWSPSDRRKAAGIKPKIGSPNMNIAEITRFNSIEELVIDPTGH
IPAQSSGRMKSKTSTAPSSKQE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=126, Percent_Identity=50, Blast_Score=131, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_ACIAD (Q6FE71)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045459.1
- STRING:   Q6FE71
- GeneID:   2879580
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0730
- NMPDR:   fig|62977.3.peg.473
- eggNOG:   COG0838
- HOGENOM:   HBG605540
- OMA:   ALYLYAY
- PhylomeDB:   Q6FE71
- ProtClustDB:   CLSK830510
- BioCyc:   ASP62977:ACIAD0730-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 20052; Mature: 19921

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16e382dc)-; HASH(0x16e221e4)-; HASH(0x16230b48)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAITPYDWAIIAFVIGVTFLCVFMLTVPLLLGGKSWGRAKQEQFESGVVSAGGARIRLS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEEE
AKFYLVAIFFVVFDLEALYLYAWATSVREVGWMGFTTMVIFVVDLLIALIYVFATGALTW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SPSDRRKAAGIKPKIGSPNMNIAEITRFNSIEELVIDPTGHIPAQSSGRMKSKTSTAPSS
CCCCHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHEECCCCCCCCCCCCCCCCCCCCCCCC
KQE
CCH
>Mature Secondary Structure 
SAITPYDWAIIAFVIGVTFLCVFMLTVPLLLGGKSWGRAKQEQFESGVVSAGGARIRLS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCEEEEE
AKFYLVAIFFVVFDLEALYLYAWATSVREVGWMGFTTMVIFVVDLLIALIYVFATGALTW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SPSDRRKAAGIKPKIGSPNMNIAEITRFNSIEELVIDPTGHIPAQSSGRMKSKTSTAPSS
CCCCHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHEECCCCCCCCCCCCCCCCCCCCCCCC
KQE
CCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA