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The map label for this gene is namA [H]

Identifier: 50083932

GI number: 50083932

Start: 696960

End: 698072

Strand: Direct

Name: namA [H]

Synonym: ACIAD0709

Alternate gene names: 50083932

Gene position: 696960-698072 (Clockwise)

Preceding gene: 50083931

Following gene: 50083933

Centisome position: 19.37

GC content: 45.46

Gene sequence:

>1113_bases
GTGGCAAAGCTATTTGAAAATATTCAGTTTGATACATTGCGCCTGAGCAATAAAATTATTATTGCACCGATGTGTCAGTA
CTCTGCTACAGATCAGGGTGAAATCACCTATTGGCATGAACAGCAGTGGGCAAACTATGCCTTATCTGGTGCAGGATTAT
GTATTATTGAAGCCTCTGCGGTGCAGGCAGCGGGACGAATCAGTTATGCCGATGTTGGTCTTTGGAATGATAACCAACGT
GATCAGATCAAGATGTTGCTGAATAAGATCAAACACCTTTCACCTGTCCCTTTTGGGATTCAGCTCGCACATGCGGGACG
AAAAGCATCCACAGACAAGCCCTGGTTAGGTAAAGGGCAAATCCCGCCAGATCATGTACATGGCTGGCAAACAGTCGCGC
CAAGTAGCATTGCATTTGGAGAACATGATCTGGCTCCACATGCCTTAACACGAGATGAAATCCAGCAGATTCAGGCTGAT
TTTGCAGCTTCTGCCGTCAGAGCAGTTGAGGCAGGATTTAAACTTATTGAAATTCATGCGGCACATGGCTATTTATTGCA
TCAATTTTTATCGCCACTTTCAAATTTACGTGATGATGAATATGGCGGTTCATTTGAAAATCGTATCCGCATGACACTTG
AGGTTTTGCAAGCTGTGAAAGCGGTCGTGCCAGAAGGTTTTCCTGTAGGTGTACGTATTTCTGCAACAGACTGGATGCCA
ACCCAAAGTTGGGATATCGAATCCAGTGTGGGGCTATCGCAGGCTTTGGAACAGTTAGGTGCCGCTTATATTCATGTATC
TAGTGGTGGCCTGCACGTCATGCAAGATATTAAAGTGGGCGCAAATTATCAGGTGCCATTTGCGGCACAAATTAAGCAAA
ACGTATCAATTCCTGTGATTGCAGTGGGCTTGATTACCGAACCTGATCAGGCCGAAGCGATTTTACAGAATGATGAGGCT
GACGCTATTGCGTTGGCACGTGCAATGCAGTATGACCCTCGCTGGCCTTGGCATGCTGCTGCTGCGCTTGGTGCAGAAAT
TGAGATTTCACCTCAGTATCTACGTTGTCAGCCGCATGGTTTGAAACAGTTATTTAAAGCATTTTCTCATTGA

Upstream 100 bases:

>100_bases
AATGATGGCAATAGCCGTTTTTTTGAACCGGCAGATGGTCGAAACTGGAGTGCAGGTTTGCGTGTAAGCAAACAATTTTA
ATCTGATCTAGAGGTGAAAC

Downstream 100 bases:

>100_bases
TTCACGCGAGAGAAAGATTTTCAGATCGAAATTTTTCTCTTCTGACAAAACCCAAGGAAGCCTAGGTGGTTGTTCAAGTT
ATTGTTCCGATTTTCCTGTT

Product: FMN oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MAKLFENIQFDTLRLSNKIIIAPMCQYSATDQGEITYWHEQQWANYALSGAGLCIIEASAVQAAGRISYADVGLWNDNQR
DQIKMLLNKIKHLSPVPFGIQLAHAGRKASTDKPWLGKGQIPPDHVHGWQTVAPSSIAFGEHDLAPHALTRDEIQQIQAD
FAASAVRAVEAGFKLIEIHAAHGYLLHQFLSPLSNLRDDEYGGSFENRIRMTLEVLQAVKAVVPEGFPVGVRISATDWMP
TQSWDIESSVGLSQALEQLGAAYIHVSSGGLHVMQDIKVGANYQVPFAAQIKQNVSIPVIAVGLITEPDQAEAILQNDEA
DAIALARAMQYDPRWPWHAAAALGAEIEISPQYLRCQPHGLKQLFKAFSH

Sequences:

>Translated_370_residues
MAKLFENIQFDTLRLSNKIIIAPMCQYSATDQGEITYWHEQQWANYALSGAGLCIIEASAVQAAGRISYADVGLWNDNQR
DQIKMLLNKIKHLSPVPFGIQLAHAGRKASTDKPWLGKGQIPPDHVHGWQTVAPSSIAFGEHDLAPHALTRDEIQQIQAD
FAASAVRAVEAGFKLIEIHAAHGYLLHQFLSPLSNLRDDEYGGSFENRIRMTLEVLQAVKAVVPEGFPVGVRISATDWMP
TQSWDIESSVGLSQALEQLGAAYIHVSSGGLHVMQDIKVGANYQVPFAAQIKQNVSIPVIAVGLITEPDQAEAILQNDEA
DAIALARAMQYDPRWPWHAAAALGAEIEISPQYLRCQPHGLKQLFKAFSH
>Mature_369_residues
AKLFENIQFDTLRLSNKIIIAPMCQYSATDQGEITYWHEQQWANYALSGAGLCIIEASAVQAAGRISYADVGLWNDNQRD
QIKMLLNKIKHLSPVPFGIQLAHAGRKASTDKPWLGKGQIPPDHVHGWQTVAPSSIAFGEHDLAPHALTRDEIQQIQADF
AASAVRAVEAGFKLIEIHAAHGYLLHQFLSPLSNLRDDEYGGSFENRIRMTLEVLQAVKAVVPEGFPVGVRISATDWMPT
QSWDIESSVGLSQALEQLGAAYIHVSSGGLHVMQDIKVGANYQVPFAAQIKQNVSIPVIAVGLITEPDQAEAILQNDEAD
AIALARAMQYDPRWPWHAAAALGAEIEISPQYLRCQPHGLKQLFKAFSH

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=373, Percent_Identity=31.0991957104558, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789463, Length=240, Percent_Identity=30.8333333333333, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI72001454, Length=251, Percent_Identity=29.8804780876494, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17559802, Length=251, Percent_Identity=31.4741035856574, Blast_Score=104, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17559804, Length=252, Percent_Identity=30.1587301587302, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17540738, Length=251, Percent_Identity=30.2788844621514, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17565138, Length=250, Percent_Identity=27.6, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17564188, Length=202, Percent_Identity=30.6930693069307, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17566914, Length=124, Percent_Identity=38.7096774193548, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6325086, Length=242, Percent_Identity=31.8181818181818, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321973, Length=105, Percent_Identity=46.6666666666667, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40679; Mature: 40547

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLFENIQFDTLRLSNKIIIAPMCQYSATDQGEITYWHEQQWANYALSGAGLCIIEASA
CCCHHHCCCEEEEEECCEEEEEEECCCCCCCCCCEEEEEHHHHHHHEECCCCEEEEEHHH
VQAAGRISYADVGLWNDNQRDQIKMLLNKIKHLSPVPFGIQLAHAGRKASTDKPWLGKGQ
HHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCC
IPPDHVHGWQTVAPSSIAFGEHDLAPHALTRDEIQQIQADFAASAVRAVEAGFKLIEIHA
CCHHHCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
AHGYLLHQFLSPLSNLRDDEYGGSFENRIRMTLEVLQAVKAVVPEGFPVGVRISATDWMP
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
TQSWDIESSVGLSQALEQLGAAYIHVSSGGLHVMQDIKVGANYQVPFAAQIKQNVSIPVI
CCCCCCHHHCCHHHHHHHCCCEEEEEECCCEEEEEEEECCCCCCCCCHHHHHCCCCCEEE
AVGLITEPDQAEAILQNDEADAIALARAMQYDPRWPWHAAAALGAEIEISPQYLRCQPHG
EEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCCEEECCCHH
LKQLFKAFSH
HHHHHHHHCC
>Mature Secondary Structure 
AKLFENIQFDTLRLSNKIIIAPMCQYSATDQGEITYWHEQQWANYALSGAGLCIIEASA
CCHHHCCCEEEEEECCEEEEEEECCCCCCCCCCEEEEEHHHHHHHEECCCCEEEEEHHH
VQAAGRISYADVGLWNDNQRDQIKMLLNKIKHLSPVPFGIQLAHAGRKASTDKPWLGKGQ
HHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCC
IPPDHVHGWQTVAPSSIAFGEHDLAPHALTRDEIQQIQADFAASAVRAVEAGFKLIEIHA
CCHHHCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
AHGYLLHQFLSPLSNLRDDEYGGSFENRIRMTLEVLQAVKAVVPEGFPVGVRISATDWMP
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
TQSWDIESSVGLSQALEQLGAAYIHVSSGGLHVMQDIKVGANYQVPFAAQIKQNVSIPVI
CCCCCCHHHCCHHHHHHHCCCEEEEEECCCEEEEEEEECCCCCCCCCHHHHHCCCCCEEE
AVGLITEPDQAEAILQNDEADAIALARAMQYDPRWPWHAAAALGAEIEISPQYLRCQPHG
EEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCCEEECCCHH
LKQLFKAFSH
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA