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The map label for this gene is accD

Identifier: 50083875

GI number: 50083875

Start: 631520

End: 632416

Strand: Direct

Name: accD

Synonym: ACIAD0643

Alternate gene names: 50083875

Gene position: 631520-632416 (Clockwise)

Preceding gene: 50083874

Following gene: 50083876

Centisome position: 17.55

GC content: 44.37

Gene sequence:

>897_bases
ATGAATCAAGAAGTGAAATCAGGTAAAATCCTAAGCCCATCGACGCCATGGACTGAACGTCAGGTACCAGGAATACAAGT
TGCCAATGAACAACAATCGCTCAAGGCAACATCGACTGAGCCAACGATTGAGTGTCCTGAGTGTCATGCACTGGTGACTC
GTACTGCAATTGCATTTAATGCCTATGTTTGTCCGTCATGCGATGAACACTTGCGTATGAAAGCGCGTGATCGTTTGACT
TGGTTCTTTGATCAAGTTGATGCTGAACTAGGTCAAGAATTTTCTGCTAAAGACCCACTTAAATTTGTAGATAGCAAACC
TTACCCAGAGCGTATGCGTGAAGCGCAAAGCAAAACAGGTGAAACCGAAGCTTTGGTGGTGATGCAAGGTACCCTCAATA
ATGTCTCAATGATTGCTTGCGCATTTGAATTTGACTTTATGGGTGGTTCAATGGGCACTGTCGTTGGCGACCGTTTCGTT
CAAGCGGCAGAACGTGCAATTGAACAAAAGCAAGCATTGATCTGTTTTGCTGCATCAGGCGGTGCGCGTATGCAAGAAGG
TATGCTGTCGCTTATGCAAATGGCGCGTACTTCTGCTGCAATTCAACGCATGAAAGATGCTGGTCTGCCTTATATCGTTG
TATTAACTCATCCTGTATATGGTGGTGTAACTGCATCATTGGCAATGCTTGGTGATGTGCATATTGCTGAGCCTAAAGCC
ATGATCGGTTTTGCGGGTAAACGTGTGATTGAACAAACTGTACGTGAAACACTAGAAGAACCGTTCCAGCGTGCCGAATA
TTTGCTTGATCACGGTGTGGTCGATCAAATTGTTCATCGTCATGCATTACGTGATACTGTATCTCGTATTGTGTCTAAAC
TGATGAATTTACCTTGA

Upstream 100 bases:

>100_bases
GTGCTTTCGTTAAACCTTTTGCTACGTTAGCAATCGACCAAGCGGTTGAACAAACGGTCAATAAAGTCAAGGAGCTTCGA
GCAGCGCTCGATGAGTTAGT

Downstream 100 bases:

>100_bases
AACTCGACGCTCCAAGTATCCAAGATGATTTAATGACATGGCTCACATATTGGGGCCATGTTCACGTTACGGGGATTGAT
TTAGGTCTAGAACGTGTCAT

Product: acetylCoA carboxylase, beta subunit

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNQEVKSGKILSPSTPWTERQVPGIQVANEQQSLKATSTEPTIECPECHALVTRTAIAFNAYVCPSCDEHLRMKARDRLT
WFFDQVDAELGQEFSAKDPLKFVDSKPYPERMREAQSKTGETEALVVMQGTLNNVSMIACAFEFDFMGGSMGTVVGDRFV
QAAERAIEQKQALICFAASGGARMQEGMLSLMQMARTSAAIQRMKDAGLPYIVVLTHPVYGGVTASLAMLGDVHIAEPKA
MIGFAGKRVIEQTVRETLEEPFQRAEYLLDHGVVDQIVHRHALRDTVSRIVSKLMNLP

Sequences:

>Translated_298_residues
MNQEVKSGKILSPSTPWTERQVPGIQVANEQQSLKATSTEPTIECPECHALVTRTAIAFNAYVCPSCDEHLRMKARDRLT
WFFDQVDAELGQEFSAKDPLKFVDSKPYPERMREAQSKTGETEALVVMQGTLNNVSMIACAFEFDFMGGSMGTVVGDRFV
QAAERAIEQKQALICFAASGGARMQEGMLSLMQMARTSAAIQRMKDAGLPYIVVLTHPVYGGVTASLAMLGDVHIAEPKA
MIGFAGKRVIEQTVRETLEEPFQRAEYLLDHGVVDQIVHRHALRDTVSRIVSKLMNLP
>Mature_298_residues
MNQEVKSGKILSPSTPWTERQVPGIQVANEQQSLKATSTEPTIECPECHALVTRTAIAFNAYVCPSCDEHLRMKARDRLT
WFFDQVDAELGQEFSAKDPLKFVDSKPYPERMREAQSKTGETEALVVMQGTLNNVSMIACAFEFDFMGGSMGTVVGDRFV
QAAERAIEQKQALICFAASGGARMQEGMLSLMQMARTSAAIQRMKDAGLPYIVVLTHPVYGGVTASLAMLGDVHIAEPKA
MIGFAGKRVIEQTVRETLEEPFQRAEYLLDHGVVDQIVHRHALRDTVSRIVSKLMNLP

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=256, Percent_Identity=57.8125, Blast_Score=303, Evalue=8e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_ACIAD (Q6FEE5)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045385.1
- ProteinModelPortal:   Q6FEE5
- SMR:   Q6FEE5
- STRING:   Q6FEE5
- GeneID:   2878573
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0643
- NMPDR:   fig|62977.3.peg.288
- eggNOG:   COG0777
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- PhylomeDB:   Q6FEE5
- ProtClustDB:   CLSK830498
- BioCyc:   ASP62977:ACIAD0643-MONOMER
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 32953; Mature: 32953

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQEVKSGKILSPSTPWTERQVPGIQVANEQQSLKATSTEPTIECPECHALVTRTAIAFN
CCCCCCCCEEECCCCCCCCCCCCCCEECCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHC
AYVCPSCDEHLRMKARDRLTWFFDQVDAELGQEFSAKDPLKFVDSKPYPERMREAQSKTG
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHCCC
ETEALVVMQGTLNNVSMIACAFEFDFMGGSMGTVVGDRFVQAAERAIEQKQALICFAASG
CCEEEEEEECCCCCCEEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCC
GARMQEGMLSLMQMARTSAAIQRMKDAGLPYIVVLTHPVYGGVTASLAMLGDVHIAEPKA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCEECCCHH
MIGFAGKRVIEQTVRETLEEPFQRAEYLLDHGVVDQIVHRHALRDTVSRIVSKLMNLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNQEVKSGKILSPSTPWTERQVPGIQVANEQQSLKATSTEPTIECPECHALVTRTAIAFN
CCCCCCCCEEECCCCCCCCCCCCCCEECCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHC
AYVCPSCDEHLRMKARDRLTWFFDQVDAELGQEFSAKDPLKFVDSKPYPERMREAQSKTG
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHCCC
ETEALVVMQGTLNNVSMIACAFEFDFMGGSMGTVVGDRFVQAAERAIEQKQALICFAASG
CCEEEEEEECCCCCCEEEEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCC
GARMQEGMLSLMQMARTSAAIQRMKDAGLPYIVVLTHPVYGGVTASLAMLGDVHIAEPKA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCEECCCHH
MIGFAGKRVIEQTVRETLEEPFQRAEYLLDHGVVDQIVHRHALRDTVSRIVSKLMNLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA