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The map label for this gene is baeR [H]

Identifier: 50083860

GI number: 50083860

Start: 616168

End: 616854

Strand: Direct

Name: baeR [H]

Synonym: ACIAD0627

Alternate gene names: 50083860

Gene position: 616168-616854 (Clockwise)

Preceding gene: 50083859

Following gene: 50083864

Centisome position: 17.12

GC content: 42.36

Gene sequence:

>687_bases
ATGAAACATGTGATGTTAGTTGAAGATGAAGTGGAATTAGCTCATCTGGTTCGTGATTACTTAGAAGCATCTGGATTTGA
AGTCAGTATGTTTCATGATGGACAAGAAGCCTATGAGAGCTTTTTACAGCGCAAGCCTAACCTGATGATCCTCGATTTAA
TGGTACCGCGTATGGATGGTCTGACTATTTGTCGTAAAGTGCGTGAACAATCTGACCTTCCTATTATTATGGTCACCGCA
CGTACCGAAGAAATAGATCGGGTTCTAGGCTTAAACATGGGTGCCGACGATTACGTTTGTAAGCCATTTAGCCCTAAAGA
ACTGGTGGCACGCGTTCAGGCAGTATTACGTCGTCTGGATCGTAAAGCAGAACCAGAACAAAATGATCTGTTTCGTATCG
ACAAAGCGCAACAACGTATCTGGTACAAACAAAAATCTTTAAACTTAACACCGACCGAATTTCGTTTGCTGGAGCTTTTT
TTAGAGCATTTGGGGCAGGTGTATTCACGTGCCCAGTTACTCGACCATATTAATCCAGATAGCTTTGATGTCGCAGATCG
TGTCATTGATAGTCACATTAAAAATTTGCGCCGTAAAATCAGTGAAGCCGCAGATACAGGTAATCGTCATGAGTGGGTAC
AGGCAGTGTATGGTGTTGGCTATCGTTTTGAATATCCTGAAGATTGA

Upstream 100 bases:

>100_bases
GCTTGGCGGTCAATTACGTTTTGATCATTCGCCTTTGGGTGGTCTGCGTTGCATTCTGACTTTTCCAAAAACACATTCAA
ATATTAAGGAAATTTGATCC

Downstream 100 bases:

>100_bases
TGTATAGATATTATTTGGCTTAATTAAGCATCGCTATAGGCGGTGCTTTTTTATTGTATAAATGGACTGCGCAATCCTTT
CCACCTTCGATTATAAAAAC

Product: OmpR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKHVMLVEDEVELAHLVRDYLEASGFEVSMFHDGQEAYESFLQRKPNLMILDLMVPRMDGLTICRKVREQSDLPIIMVTA
RTEEIDRVLGLNMGADDYVCKPFSPKELVARVQAVLRRLDRKAEPEQNDLFRIDKAQQRIWYKQKSLNLTPTEFRLLELF
LEHLGQVYSRAQLLDHINPDSFDVADRVIDSHIKNLRRKISEAADTGNRHEWVQAVYGVGYRFEYPED

Sequences:

>Translated_228_residues
MKHVMLVEDEVELAHLVRDYLEASGFEVSMFHDGQEAYESFLQRKPNLMILDLMVPRMDGLTICRKVREQSDLPIIMVTA
RTEEIDRVLGLNMGADDYVCKPFSPKELVARVQAVLRRLDRKAEPEQNDLFRIDKAQQRIWYKQKSLNLTPTEFRLLELF
LEHLGQVYSRAQLLDHINPDSFDVADRVIDSHIKNLRRKISEAADTGNRHEWVQAVYGVGYRFEYPED
>Mature_228_residues
MKHVMLVEDEVELAHLVRDYLEASGFEVSMFHDGQEAYESFLQRKPNLMILDLMVPRMDGLTICRKVREQSDLPIIMVTA
RTEEIDRVLGLNMGADDYVCKPFSPKELVARVQAVLRRLDRKAEPEQNDLFRIDKAQQRIWYKQKSLNLTPTEFRLLELF
LEHLGQVYSRAQLLDHINPDSFDVADRVIDSHIKNLRRKISEAADTGNRHEWVQAVYGVGYRFEYPED

Specific function: Member of the two-component regulatory system BaeS/BaeR. Activates the mdtABCD operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=48.6607142857143, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=40.0881057268723, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=39.8268398268398, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=36.2445414847162, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1790860, Length=201, Percent_Identity=40.2985074626866, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=31.6017316017316, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=32.2727272727273, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=34.3612334801762, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=34.2105263157895, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787229, Length=208, Percent_Identity=34.1346153846154, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=32.2727272727273, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=30.9322033898305, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=32.2869955156951, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=29.5454545454545, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=27.6422764227642, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788550, Length=125, Percent_Identity=30.4, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26678; Mature: 26678

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHVMLVEDEVELAHLVRDYLEASGFEVSMFHDGQEAYESFLQRKPNLMILDLMVPRMDG
CCCEEEECHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEEEEEHHCCCCH
LTICRKVREQSDLPIIMVTARTEEIDRVLGLNMGADDYVCKPFSPKELVARVQAVLRRLD
HHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHH
RKAEPEQNDLFRIDKAQQRIWYKQKSLNLTPTEFRLLELFLEHLGQVYSRAQLLDHINPD
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SFDVADRVIDSHIKNLRRKISEAADTGNRHEWVQAVYGVGYRFEYPED
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCC
>Mature Secondary Structure
MKHVMLVEDEVELAHLVRDYLEASGFEVSMFHDGQEAYESFLQRKPNLMILDLMVPRMDG
CCCEEEECHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCEEEEEEHHCCCCH
LTICRKVREQSDLPIIMVTARTEEIDRVLGLNMGADDYVCKPFSPKELVARVQAVLRRLD
HHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHH
RKAEPEQNDLFRIDKAQQRIWYKQKSLNLTPTEFRLLELFLEHLGQVYSRAQLLDHINPD
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SFDVADRVIDSHIKNLRRKISEAADTGNRHEWVQAVYGVGYRFEYPED
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]