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The map label for this gene is baeS [H]

Identifier: 50083859

GI number: 50083859

Start: 614467

End: 616164

Strand: Direct

Name: baeS [H]

Synonym: ACIAD0626

Alternate gene names: 50083859

Gene position: 614467-616164 (Clockwise)

Preceding gene: 50083855

Following gene: 50083860

Centisome position: 17.08

GC content: 41.46

Gene sequence:

>1698_bases
TTGAAAATCCGCCGTGTACCGATAGCACTTCGACTGTTCCTGACGGTTTTATTGACAACACTGGTCATTACGACGTTGAG
TCTAGGTGTATTGCACTGGACCATGCAAAAAAACTTTGCCAAGTATGTTGCAGATGTAGAGATGCAGAAACTTGATCATC
TGATTACCAATCTGGCGAATGTTTATAATATTTATGGTGATTGGGGAAATGCGATTCAGGCGCAAATTTTACAAATCGAA
GGCAATGCTGCACCAGATGATTATGATCGACTCTCTCGCTGGTGGTTACGGCGGCAATATGATATTGCATTACAGCAGCG
TTTTTTTAATGAACAAAACATGATTATGCTTTCACCGAGTCTGGCGAATGAAAATCGACTGAAAAATAGACCGATATTGG
ATGAACAGGAGCGACGTTTTTTACAGGATAATCTACCTTCTGAATATCAACCATTTGAAGGTCTTAAGTTTCCACTCAAT
TCAAATCAAAATTTTTTCCGTCCAGACGGTGACAACAAGAAAAAAGAGCCACCGCGAGGGCCTGAAATGGCCAATCTGAT
GCACCACGATGGGAAAAAACGTTTCATTGCCATGCCAGATCGTTTAGGTTTAAGTTCGCGTCTTTCATTATATGATGCCA
AACATCAGTTCATTGTAGGCGAATACTCCAATGAGCAAATTTCATATCGTCCAATTATGGTCAATGATCGGGTGGTGGGT
TATTTAGGCTTAAAACCTGTACTAGATGAAGATGATGCCTTAAGTATTAATTTTTTTAGTAACCAGAAACGATTTTTGTT
GCTGATTTACCTGTTTTCTGTATTGGCGAGCTTGGTGGCAGCACTGTTACTTGCAACCTATTTCAAAAAACCTATTCAGC
GTTTGCTGAATGCCACACGAGAGCTAACACGTGGTCGCTATCAGCATCAGGTAGAGATTAAACGTAATGATGAACTGGGA
GACTTGGCAACTGAACTGAATCAATTGGCCAAAATTCTGTATCAACATGAAGAATCTCGTCGTCAATGGGTGGCAGATAC
CTCACATGAGTTGAAAACTCCGTTAAGCGTTTTACAGGCTCAGATTGAAGCGATGCAAGATGGTATTCGTAAGGCAACAC
CAGAACATTTAGCAGCCATGATGAGTCAGATCAGTAGCCTTAAAAAACTGACTCAGGATCTGGCCGATCTGGCTCAGGCC
GATGCGCAACAATTAAAATGTTATTTTGCTGAAGTCGACCCTTGGGATGTTATTTTGCAAGAAGTTGAAAACTTTAAGCC
TAAAATTGAACAGGCTCAGCTTTCTATTGTAGTAGAGGGTGCAGGCACCAAGTTACAATTAGATATAGATCGCTTTAAAC
AAATTATGGTGAACTTGCTAAGCAACAGCGTACGTTACACCGAAGCAGGTGGACAGATTAAGTTGCATACACTTCAAGAT
GAAGAACAGTGGAGTGTGATTGTGGATGACAGTCCTTTGGGCTTAAACGATGAGCAACTCTCTCGATTGGGTGAGCGTTT
TTATCGTGTTGATGACTCACGTACACGCAGCACTGGAGGTACAGGATTAGGTCTGGCGTTGTCATATAAGTTAGCACAGG
CGCTTGGCGGTCAATTACGTTTTGATCATTCGCCTTTGGGTGGTCTGCGTTGCATTCTGACTTTTCCAAAAACACATTCA
AATATTAAGGAAATTTGA

Upstream 100 bases:

>100_bases
ATGTTAAAGATTAAGCAATAAACATGAAGGAACAATGGAGAGTTTTTTTAATGAGCGTTGGTTACAATAGTTTATATACA
AGAAAAATGAGAGTTTTCTT

Downstream 100 bases:

>100_bases
TCCATGAAACATGTGATGTTAGTTGAAGATGAAGTGGAATTAGCTCATCTGGTTCGTGATTACTTAGAAGCATCTGGATT
TGAAGTCAGTATGTTTCATG

Product: kinase sensor component of a two component signal transduction system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MKIRRVPIALRLFLTVLLTTLVITTLSLGVLHWTMQKNFAKYVADVEMQKLDHLITNLANVYNIYGDWGNAIQAQILQIE
GNAAPDDYDRLSRWWLRRQYDIALQQRFFNEQNMIMLSPSLANENRLKNRPILDEQERRFLQDNLPSEYQPFEGLKFPLN
SNQNFFRPDGDNKKKEPPRGPEMANLMHHDGKKRFIAMPDRLGLSSRLSLYDAKHQFIVGEYSNEQISYRPIMVNDRVVG
YLGLKPVLDEDDALSINFFSNQKRFLLLIYLFSVLASLVAALLLATYFKKPIQRLLNATRELTRGRYQHQVEIKRNDELG
DLATELNQLAKILYQHEESRRQWVADTSHELKTPLSVLQAQIEAMQDGIRKATPEHLAAMMSQISSLKKLTQDLADLAQA
DAQQLKCYFAEVDPWDVILQEVENFKPKIEQAQLSIVVEGAGTKLQLDIDRFKQIMVNLLSNSVRYTEAGGQIKLHTLQD
EEQWSVIVDDSPLGLNDEQLSRLGERFYRVDDSRTRSTGGTGLGLALSYKLAQALGGQLRFDHSPLGGLRCILTFPKTHS
NIKEI

Sequences:

>Translated_565_residues
MKIRRVPIALRLFLTVLLTTLVITTLSLGVLHWTMQKNFAKYVADVEMQKLDHLITNLANVYNIYGDWGNAIQAQILQIE
GNAAPDDYDRLSRWWLRRQYDIALQQRFFNEQNMIMLSPSLANENRLKNRPILDEQERRFLQDNLPSEYQPFEGLKFPLN
SNQNFFRPDGDNKKKEPPRGPEMANLMHHDGKKRFIAMPDRLGLSSRLSLYDAKHQFIVGEYSNEQISYRPIMVNDRVVG
YLGLKPVLDEDDALSINFFSNQKRFLLLIYLFSVLASLVAALLLATYFKKPIQRLLNATRELTRGRYQHQVEIKRNDELG
DLATELNQLAKILYQHEESRRQWVADTSHELKTPLSVLQAQIEAMQDGIRKATPEHLAAMMSQISSLKKLTQDLADLAQA
DAQQLKCYFAEVDPWDVILQEVENFKPKIEQAQLSIVVEGAGTKLQLDIDRFKQIMVNLLSNSVRYTEAGGQIKLHTLQD
EEQWSVIVDDSPLGLNDEQLSRLGERFYRVDDSRTRSTGGTGLGLALSYKLAQALGGQLRFDHSPLGGLRCILTFPKTHS
NIKEI
>Mature_565_residues
MKIRRVPIALRLFLTVLLTTLVITTLSLGVLHWTMQKNFAKYVADVEMQKLDHLITNLANVYNIYGDWGNAIQAQILQIE
GNAAPDDYDRLSRWWLRRQYDIALQQRFFNEQNMIMLSPSLANENRLKNRPILDEQERRFLQDNLPSEYQPFEGLKFPLN
SNQNFFRPDGDNKKKEPPRGPEMANLMHHDGKKRFIAMPDRLGLSSRLSLYDAKHQFIVGEYSNEQISYRPIMVNDRVVG
YLGLKPVLDEDDALSINFFSNQKRFLLLIYLFSVLASLVAALLLATYFKKPIQRLLNATRELTRGRYQHQVEIKRNDELG
DLATELNQLAKILYQHEESRRQWVADTSHELKTPLSVLQAQIEAMQDGIRKATPEHLAAMMSQISSLKKLTQDLADLAQA
DAQQLKCYFAEVDPWDVILQEVENFKPKIEQAQLSIVVEGAGTKLQLDIDRFKQIMVNLLSNSVRYTEAGGQIKLHTLQD
EEQWSVIVDDSPLGLNDEQLSRLGERFYRVDDSRTRSTGGTGLGLALSYKLAQALGGQLRFDHSPLGGLRCILTFPKTHS
NIKEI

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=437, Percent_Identity=32.9519450800915, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1787894, Length=270, Percent_Identity=29.6296296296296, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=29.3617021276596, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1786600, Length=273, Percent_Identity=29.3040293040293, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1790346, Length=290, Percent_Identity=27.5862068965517, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786783, Length=331, Percent_Identity=26.5861027190332, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI87081816, Length=273, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787374, Length=335, Percent_Identity=26.2686567164179, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788279, Length=285, Percent_Identity=25.6140350877193, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790861, Length=335, Percent_Identity=25.0746268656716, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789149, Length=284, Percent_Identity=26.7605633802817, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1789403, Length=249, Percent_Identity=26.9076305220884, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790551, Length=282, Percent_Identity=24.468085106383, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=308, Percent_Identity=25.3246753246753, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=246, Percent_Identity=26.0162601626016, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=24.6861924686192, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788549, Length=223, Percent_Identity=24.6636771300448, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64841; Mature: 64841

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRRVPIALRLFLTVLLTTLVITTLSLGVLHWTMQKNFAKYVADVEMQKLDHLITNLAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYNIYGDWGNAIQAQILQIEGNAAPDDYDRLSRWWLRRQYDIALQQRFFNEQNMIMLSPS
HHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
LANENRLKNRPILDEQERRFLQDNLPSEYQPFEGLKFPLNSNQNFFRPDGDNKKKEPPRG
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PEMANLMHHDGKKRFIAMPDRLGLSSRLSLYDAKHQFIVGEYSNEQISYRPIMVNDRVVG
CHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCEEECEEEECCCEEE
YLGLKPVLDEDDALSINFFSNQKRFLLLIYLFSVLASLVAALLLATYFKKPIQRLLNATR
EECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELTRGRYQHQVEIKRNDELGDLATELNQLAKILYQHEESRRQWVADTSHELKTPLSVLQA
HHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
QIEAMQDGIRKATPEHLAAMMSQISSLKKLTQDLADLAQADAQQLKCYFAEVDPWDVILQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
EVENFKPKIEQAQLSIVVEGAGTKLQLDIDRFKQIMVNLLSNSVRYTEAGGQIKLHTLQD
HHHHCCCCCCCEEEEEEEECCCCEEEEEHHHHHHHHHHHHHCCCEEEECCCEEEEEEECC
EEQWSVIVDDSPLGLNDEQLSRLGERFYRVDDSRTRSTGGTGLGLALSYKLAQALGGQLR
CCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
FDHSPLGGLRCILTFPKTHSNIKEI
ECCCCCCCEEEEEECCCCCCHHCCC
>Mature Secondary Structure
MKIRRVPIALRLFLTVLLTTLVITTLSLGVLHWTMQKNFAKYVADVEMQKLDHLITNLAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYNIYGDWGNAIQAQILQIEGNAAPDDYDRLSRWWLRRQYDIALQQRFFNEQNMIMLSPS
HHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCC
LANENRLKNRPILDEQERRFLQDNLPSEYQPFEGLKFPLNSNQNFFRPDGDNKKKEPPRG
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PEMANLMHHDGKKRFIAMPDRLGLSSRLSLYDAKHQFIVGEYSNEQISYRPIMVNDRVVG
CHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCEEECEEEECCCEEE
YLGLKPVLDEDDALSINFFSNQKRFLLLIYLFSVLASLVAALLLATYFKKPIQRLLNATR
EECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELTRGRYQHQVEIKRNDELGDLATELNQLAKILYQHEESRRQWVADTSHELKTPLSVLQA
HHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
QIEAMQDGIRKATPEHLAAMMSQISSLKKLTQDLADLAQADAQQLKCYFAEVDPWDVILQ
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
EVENFKPKIEQAQLSIVVEGAGTKLQLDIDRFKQIMVNLLSNSVRYTEAGGQIKLHTLQD
HHHHCCCCCCCEEEEEEEECCCCEEEEEHHHHHHHHHHHHHCCCEEEECCCEEEEEEECC
EEQWSVIVDDSPLGLNDEQLSRLGERFYRVDDSRTRSTGGTGLGLALSYKLAQALGGQLR
CCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
FDHSPLGGLRCILTFPKTHSNIKEI
ECCCCCCCEEEEEECCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]