Click here to switch to the map view.

The map label for this gene is gntK [H]

Identifier: 50083783

GI number: 50083783

Start: 536472

End: 536984

Strand: Direct

Name: gntK [H]

Synonym: ACIAD0545

Alternate gene names: 50083783

Gene position: 536472-536984 (Clockwise)

Preceding gene: 50083782

Following gene: 50083784

Centisome position: 14.91

GC content: 43.08

Gene sequence:

>513_bases
ATGATTGTGATTGCAATGGGTGTCTGTGGAACAGGTAAATCGCTAATTGGTGAGTTATTGTCAGCGCGTTTGGCTTGTGA
GTTTCTTGATGGTGATACGCTGCATTCGGCTGCTAATAAAAGCAAGATGAGTCAGGGTATTCCGCTTACCGATGAAGATC
GTTTGCCGTGGTTGCAAGCCATTCGTCAGGCAATCGAAGCGAAACAGAAAATGGGTCAAACGGCGGTTTTTACCTGCTCT
TCGCTCAAGAGAATGTATCGCGATATTTTACGTGGTGATGATCAAAATGTGCAGTTTATCTATTTAAAAGGCTCATTTGA
GTTATTGCAGCAACGTCTTGCTGAGCGCGCTGGACATTTCTTTGATCCATCATTATTACAAACGCAGCTCGATACATTGG
AAGAACCAGATGTGAATGAAGCAATTATTGTTGATATCACGCTGACACCGAAACAGATCATTGAGCAAATTACCCAGAAG
TTAGGCATAAGCAACAGTGTCTGTCGCGGTTAA

Upstream 100 bases:

>100_bases
ACACTTAAAACCTGGTCTGTACTGGAAACCATTATTTCGGTGCTGGGTTTGTCTTTTACGCTGCTACTGAGCGCTATCTT
ATAATTAAAGGTGAATATCC

Downstream 100 bases:

>100_bases
TCTCGTTTAAAAACTTTGTAAGTCTTGATGGCTTGTGGCCCGAAGCTGCGAGTCAGGTCAATACCAGTTTTACTACTGGT
ATCTATAGAAACTGAACCTG

Product: thermoresistant gluconokinase (gluconate kinase)

Products: NA

Alternate protein names: Gluconate kinase 1 [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MIVIAMGVCGTGKSLIGELLSARLACEFLDGDTLHSAANKSKMSQGIPLTDEDRLPWLQAIRQAIEAKQKMGQTAVFTCS
SLKRMYRDILRGDDQNVQFIYLKGSFELLQQRLAERAGHFFDPSLLQTQLDTLEEPDVNEAIIVDITLTPKQIIEQITQK
LGISNSVCRG

Sequences:

>Translated_170_residues
MIVIAMGVCGTGKSLIGELLSARLACEFLDGDTLHSAANKSKMSQGIPLTDEDRLPWLQAIRQAIEAKQKMGQTAVFTCS
SLKRMYRDILRGDDQNVQFIYLKGSFELLQQRLAERAGHFFDPSLLQTQLDTLEEPDVNEAIIVDITLTPKQIIEQITQK
LGISNSVCRG
>Mature_170_residues
MIVIAMGVCGTGKSLIGELLSARLACEFLDGDTLHSAANKSKMSQGIPLTDEDRLPWLQAIRQAIEAKQKMGQTAVFTCS
SLKRMYRDILRGDDQNVQFIYLKGSFELLQQRLAERAGHFFDPSLLQTQLDTLEEPDVNEAIIVDITLTPKQIIEQITQK
LGISNSVCRG

Specific function: Gluconate utilization system GNT-II. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=178, Percent_Identity=38.2022471910112, Blast_Score=126, Evalue=1e-29,
Organism=Escherichia coli, GI1790719, Length=169, Percent_Identity=46.7455621301775, Blast_Score=150, Evalue=4e-38,
Organism=Escherichia coli, GI87082265, Length=147, Percent_Identity=46.2585034013605, Blast_Score=146, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI25146487, Length=169, Percent_Identity=43.1952662721894, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320454, Length=156, Percent_Identity=36.5384615384615, Blast_Score=104, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 18883; Mature: 18883

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVIAMGVCGTGKSLIGELLSARLACEFLDGDTLHSAANKSKMSQGIPLTDEDRLPWLQA
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHH
IRQAIEAKQKMGQTAVFTCSSLKRMYRDILRGDDQNVQFIYLKGSFELLQQRLAERAGHF
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCC
FDPSLLQTQLDTLEEPDVNEAIIVDITLTPKQIIEQITQKLGISNSVCRG
CCHHHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIVIAMGVCGTGKSLIGELLSARLACEFLDGDTLHSAANKSKMSQGIPLTDEDRLPWLQA
CEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHH
IRQAIEAKQKMGQTAVFTCSSLKRMYRDILRGDDQNVQFIYLKGSFELLQQRLAERAGHF
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCC
FDPSLLQTQLDTLEEPDVNEAIIVDITLTPKQIIEQITQKLGISNSVCRG
CCHHHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]