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The map label for this gene is gntT [H]

Identifier: 50083782

GI number: 50083782

Start: 535118

End: 536455

Strand: Direct

Name: gntT [H]

Synonym: ACIAD0544

Alternate gene names: 50083782

Gene position: 535118-536455 (Clockwise)

Preceding gene: 50083781

Following gene: 50083783

Centisome position: 14.87

GC content: 45.29

Gene sequence:

>1338_bases
ATGTTGCTTATTTATACTGTAGTCGCGATTGTTGCTTTGGTCGTGATGATCGCGAAGTTTAGAATTTATCCATTTCTGGT
TCTTATTATTGTCTCGCTTGGTTTGGCTTTAGCTGTTGGGATGCCAATGGGTGATATCGTTAAATCATACGAAGCTGGTA
CTGGTAAAACCTTGGGCCATCTTGCAATTGTAATTGCACTCGGGACCATGCTCGGAAAGATGATGGCAGAGTCGGGCGGG
GCAGAACGCATTGCGATTACCTTAATTCAATGGTTTGGAGAGAAAAATATCCATTGGGCCATGATGTTTATTGGTCTTGT
GGTTGGGTTACCTGTGTTTTTTGAAGTGGGTTTTGTGCTGCTCATTCCAATTGTATTTAACATTGCTAAACGTACAGGTA
AGTCATTATTAATCGTGGGTTTGCCAATGCTGGCAGGCTTGTCGGTAGTGCATGGTTTAATTCCGCCCCATCCAGCAGCG
CTGCTCGCTGTACAGGCCTACAATGCTGATATTGGAACAACGATTGCCTACAGCCTCTTGGTGGGGGTGCCAACCGCCGT
TGTTGCAGGGCCGTTATATGCACTCTGGATCAATAAATACGTCAAATTGCCTGAAAATAATCCATTAGCAAAGCAGTTTG
TTGAAGCAGATACAAACAGAAATCGTGAGCTACCCAGCTTTAGAATTACTTTATTCACGATCATGTTGCCTGTGGTCTTG
ATGTTGGTGGGGAGCTGGGCAGATTTATTCTTTGCACCCCAAACCTTTGCCAATGATTTGCTGCGTTTTATTGGCACCTC
TGATATCGCGTTGTTAATTGCAGTACTGGTGAGCTTTGTTACCTTTGGGACTATGCAAGGTTTTACCCGTGTACAAATTG
AAAAATTCTGTGGTGGCTGCTTGGCTTCGATTGCTGGAATCATGCTGATTGTGGGTGCTGGTGGTGGTTTTGGGGGTATT
TTACGTGATAGCGGTATTTCTGATGAGATTGTTTCTACAGCCTTAAAGGCCAATCTATCGCCGTTATTGCTGGGCTGGTT
TGTTGCAGCATTGATTCGTTTGGCAACAGGTTCGGCAACTGTTGCGATGGCCACAGCCTGTAGTATTGTCGCACCGATTG
CGGCGACAGCGGGCGTCGTTGTTAGACCAGAACTCTTGGTACTTGCCACAGGTTCAGGCTCACTGGTGTTTTCGCATGTC
AATGATGCAGGCTTTTGGCTGATCAAAGAATATTTCGGTATGACGGTGGGACAAACACTTAAAACCTGGTCTGTACTGGA
AACCATTATTTCGGTGCTGGGTTTGTCTTTTACGCTGCTACTGAGCGCTATCTTATAA

Upstream 100 bases:

>100_bases
AACAGCAGGAGTCTAGCTGATTGAAGTCACTCGTTTGGGTGGTTTGCCCAAATTGTACTACTGCAAGGAGAAGTGTCACA
TGGAGACGGTTCAGGGTGGC

Downstream 100 bases:

>100_bases
TTAAAGGTGAATATCCATGATTGTGATTGCAATGGGTGTCTGTGGAACAGGTAAATCGCTAATTGGTGAGTTATTGTCAG
CGCGTTTGGCTTGTGAGTTT

Product: GntP family high-affinity gluconate permease

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MLLIYTVVAIVALVVMIAKFRIYPFLVLIIVSLGLALAVGMPMGDIVKSYEAGTGKTLGHLAIVIALGTMLGKMMAESGG
AERIAITLIQWFGEKNIHWAMMFIGLVVGLPVFFEVGFVLLIPIVFNIAKRTGKSLLIVGLPMLAGLSVVHGLIPPHPAA
LLAVQAYNADIGTTIAYSLLVGVPTAVVAGPLYALWINKYVKLPENNPLAKQFVEADTNRNRELPSFRITLFTIMLPVVL
MLVGSWADLFFAPQTFANDLLRFIGTSDIALLIAVLVSFVTFGTMQGFTRVQIEKFCGGCLASIAGIMLIVGAGGGFGGI
LRDSGISDEIVSTALKANLSPLLLGWFVAALIRLATGSATVAMATACSIVAPIAATAGVVVRPELLVLATGSGSLVFSHV
NDAGFWLIKEYFGMTVGQTLKTWSVLETIISVLGLSFTLLLSAIL

Sequences:

>Translated_445_residues
MLLIYTVVAIVALVVMIAKFRIYPFLVLIIVSLGLALAVGMPMGDIVKSYEAGTGKTLGHLAIVIALGTMLGKMMAESGG
AERIAITLIQWFGEKNIHWAMMFIGLVVGLPVFFEVGFVLLIPIVFNIAKRTGKSLLIVGLPMLAGLSVVHGLIPPHPAA
LLAVQAYNADIGTTIAYSLLVGVPTAVVAGPLYALWINKYVKLPENNPLAKQFVEADTNRNRELPSFRITLFTIMLPVVL
MLVGSWADLFFAPQTFANDLLRFIGTSDIALLIAVLVSFVTFGTMQGFTRVQIEKFCGGCLASIAGIMLIVGAGGGFGGI
LRDSGISDEIVSTALKANLSPLLLGWFVAALIRLATGSATVAMATACSIVAPIAATAGVVVRPELLVLATGSGSLVFSHV
NDAGFWLIKEYFGMTVGQTLKTWSVLETIISVLGLSFTLLLSAIL
>Mature_445_residues
MLLIYTVVAIVALVVMIAKFRIYPFLVLIIVSLGLALAVGMPMGDIVKSYEAGTGKTLGHLAIVIALGTMLGKMMAESGG
AERIAITLIQWFGEKNIHWAMMFIGLVVGLPVFFEVGFVLLIPIVFNIAKRTGKSLLIVGLPMLAGLSVVHGLIPPHPAA
LLAVQAYNADIGTTIAYSLLVGVPTAVVAGPLYALWINKYVKLPENNPLAKQFVEADTNRNRELPSFRITLFTIMLPVVL
MLVGSWADLFFAPQTFANDLLRFIGTSDIALLIAVLVSFVTFGTMQGFTRVQIEKFCGGCLASIAGIMLIVGAGGGFGGI
LRDSGISDEIVSTALKANLSPLLLGWFVAALIRLATGSATVAMATACSIVAPIAATAGVVVRPELLVLATGSGSLVFSHV
NDAGFWLIKEYFGMTVGQTLKTWSVLETIISVLGLSFTLLLSAIL

Specific function: Part Of The Gluconate Utilization System Gnt-I; High- Affinity Intake Of Gluconate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=445, Percent_Identity=43.8202247191011, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1790716, Length=448, Percent_Identity=41.0714285714286, Blast_Score=330, Evalue=8e-92,
Organism=Escherichia coli, GI1788707, Length=441, Percent_Identity=40.8163265306122, Blast_Score=298, Evalue=4e-82,
Organism=Escherichia coli, GI2367370, Length=435, Percent_Identity=39.7701149425287, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1790776, Length=448, Percent_Identity=36.1607142857143, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI48994939, Length=435, Percent_Identity=36.3218390804598, Blast_Score=240, Evalue=2e-64,
Organism=Escherichia coli, GI1789097, Length=453, Percent_Identity=33.5540838852097, Blast_Score=202, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47096; Mature: 47096

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLIYTVVAIVALVVMIAKFRIYPFLVLIIVSLGLALAVGMPMGDIVKSYEAGTGKTLGH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHH
LAIVIALGTMLGKMMAESGGAERIAITLIQWFGEKNIHWAMMFIGLVVGLPVFFEVGFVL
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LIPIVFNIAKRTGKSLLIVGLPMLAGLSVVHGLIPPHPAALLAVQAYNADIGTTIAYSLL
HHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCHHEEEEECCCCCHHHHHHHHHH
VGVPTAVVAGPLYALWINKYVKLPENNPLAKQFVEADTNRNRELPSFRITLFTIMLPVVL
HHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
MLVGSWADLFFAPQTFANDLLRFIGTSDIALLIAVLVSFVTFGTMQGFTRVQIEKFCGGC
HHHHCHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LASIAGIMLIVGAGGGFGGILRDSGISDEIVSTALKANLSPLLLGWFVAALIRLATGSAT
HHHHHHHHEEEECCCCCCCHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHH
VAMATACSIVAPIAATAGVVVRPELLVLATGSGSLVFSHVNDAGFWLIKEYFGMTVGQTL
HHHHHHHHHHHHHHHHCCEEECCCEEEEEECCCCEEEEECCCCHHHHHHHHHCCHHHHHH
KTWSVLETIISVLGLSFTLLLSAIL
HHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLLIYTVVAIVALVVMIAKFRIYPFLVLIIVSLGLALAVGMPMGDIVKSYEAGTGKTLGH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHH
LAIVIALGTMLGKMMAESGGAERIAITLIQWFGEKNIHWAMMFIGLVVGLPVFFEVGFVL
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LIPIVFNIAKRTGKSLLIVGLPMLAGLSVVHGLIPPHPAALLAVQAYNADIGTTIAYSLL
HHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCHHEEEEECCCCCHHHHHHHHHH
VGVPTAVVAGPLYALWINKYVKLPENNPLAKQFVEADTNRNRELPSFRITLFTIMLPVVL
HHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
MLVGSWADLFFAPQTFANDLLRFIGTSDIALLIAVLVSFVTFGTMQGFTRVQIEKFCGGC
HHHHCHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LASIAGIMLIVGAGGGFGGILRDSGISDEIVSTALKANLSPLLLGWFVAALIRLATGSAT
HHHHHHHHEEEECCCCCCCHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHH
VAMATACSIVAPIAATAGVVVRPELLVLATGSGSLVFSHVNDAGFWLIKEYFGMTVGQTL
HHHHHHHHHHHHHHHHCCEEECCCEEEEEECCCCEEEEECCCCHHHHHHHHHCCHHHHHH
KTWSVLETIISVLGLSFTLLLSAIL
HHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA