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The map label for this gene is pilC [H]

Identifier: 50083623

GI number: 50083623

Start: 353373

End: 354599

Strand: Reverse

Name: pilC [H]

Synonym: ACIAD0361

Alternate gene names: 50083623

Gene position: 354599-353373 (Counterclockwise)

Preceding gene: 50083624

Following gene: 50083622

Centisome position: 9.85

GC content: 41.97

Gene sequence:

>1227_bases
ATGGCAGCAAAAAAAACGCAAGTAATGCCAGTATTTGCTTATGAAGGTGTCGACCGTAAAGGCATCAAGTTAAAAGGGGA
ATTACCTGCACGCAATATGGCATTGGCCAAAGTCACTTTGCGAAAACAAGGCATTACGATTCGCACCATACGTGAAAAAC
GTAAAAATATTTTTGAAGGTTTACTTAAAAAGAAAGTCAAACCACTCGATATTGCCATTTTTACTCGTCAACTTGCCACC
ATGATGAAGGCAGGTGTTCCATTGGTACAAGCATTTGAAATTGTAGCAGAAGGGTTAGAAAACCCAGCCATGCGCGATGT
AGTGCTTGGCTTAAAAAATGAAGTTGAAGGCGGCAATACCTTTGCTGGTGCTTTACGCAAGTATCCCCAGTATTTTGATA
ACTTATTCTGTTCCCTCATTGAATCAGGGGAGCAGTCGGGTTCTCTTGAAATTATGCTAGACCGTGTGGCCGTCTATAAA
GAAAAAAGTGAAGTTCTTAAGCAAAAAATTAAAAAAGCCATGAAATATCCTGCCACCGTCATTGTAGTTGCGATTGTGGT
AACCATTATTTTGATGGTAAAGGTTGTCCCTGTATTTAAAGACTTATTTACATCATTTGGTGCAGATTTACCTGCTTTTA
CGCAACTGGTGGTCAATATGTCAAACTGGATGCAAGATTACTGGTTTATTTTAATTCTGGTGATTGGGGCTGCAATTGCA
GGTTTCCTGGAAGCTAGAAAACGCAGTAAACGCTTTCGCGATCAACTTGATCGTTTGGTTCTCCGATTGCCCATTGTTGG
TGATCTGGTCTACAAGGCAATCATTGCCCGATACAGTCGCACTTTGGCCACAACTTTTGCTGCAGGTGTACCACTCATTG
ATGCGCTGGCCTCTACCGCAGGTGCCACGAATAATACTGTTTATGAACAGGCAGTGCTTAAAATCCGAGAAGATGTATCA
ACTGGACAACAACTTAACTTCGCTATGCGCGTATCCAATCGTTTTCCAACCATGGCTATCCAAATGGTAGCGATTGGTGA
AGAATCTGGAGCACTCGATGAAATGCTGGATAAAGTCGCAAATTATTATGAAAGTGAAGTCGATCATGCGGTCGATGGCC
TTACCTCCATGATGGAACCGCTGATTATGGCGATTTTGGGCATTTTAGTCGGTGGACTGGTTATTGCAATGTATCTTCCA
ATTTTCCAAATGGGCTCTGTGGTTTAA

Upstream 100 bases:

>100_bases
CGGTCGGGTCTGAAAAAAGTGATGCAGGGGGTCACCTCGTTACAGGAAATTAATCGTGTAACCAGTGAATAATGCAAAGT
CTCAAAATAAGGATAACCAA

Downstream 100 bases:

>100_bases
TGTCTGACTTCATTCGTTATTTTTCTGAAAATTTAACTGCTTTATATTGTCTTGTAGGTATTTTAAGTCTATGTATAGGA
AGCTTTCTCAATGTTGTGAT

Product: type 4 fimbrial assembly protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MAAKKTQVMPVFAYEGVDRKGIKLKGELPARNMALAKVTLRKQGITIRTIREKRKNIFEGLLKKKVKPLDIAIFTRQLAT
MMKAGVPLVQAFEIVAEGLENPAMRDVVLGLKNEVEGGNTFAGALRKYPQYFDNLFCSLIESGEQSGSLEIMLDRVAVYK
EKSEVLKQKIKKAMKYPATVIVVAIVVTIILMVKVVPVFKDLFTSFGADLPAFTQLVVNMSNWMQDYWFILILVIGAAIA
GFLEARKRSKRFRDQLDRLVLRLPIVGDLVYKAIIARYSRTLATTFAAGVPLIDALASTAGATNNTVYEQAVLKIREDVS
TGQQLNFAMRVSNRFPTMAIQMVAIGEESGALDEMLDKVANYYESEVDHAVDGLTSMMEPLIMAILGILVGGLVIAMYLP
IFQMGSVV

Sequences:

>Translated_408_residues
MAAKKTQVMPVFAYEGVDRKGIKLKGELPARNMALAKVTLRKQGITIRTIREKRKNIFEGLLKKKVKPLDIAIFTRQLAT
MMKAGVPLVQAFEIVAEGLENPAMRDVVLGLKNEVEGGNTFAGALRKYPQYFDNLFCSLIESGEQSGSLEIMLDRVAVYK
EKSEVLKQKIKKAMKYPATVIVVAIVVTIILMVKVVPVFKDLFTSFGADLPAFTQLVVNMSNWMQDYWFILILVIGAAIA
GFLEARKRSKRFRDQLDRLVLRLPIVGDLVYKAIIARYSRTLATTFAAGVPLIDALASTAGATNNTVYEQAVLKIREDVS
TGQQLNFAMRVSNRFPTMAIQMVAIGEESGALDEMLDKVANYYESEVDHAVDGLTSMMEPLIMAILGILVGGLVIAMYLP
IFQMGSVV
>Mature_407_residues
AAKKTQVMPVFAYEGVDRKGIKLKGELPARNMALAKVTLRKQGITIRTIREKRKNIFEGLLKKKVKPLDIAIFTRQLATM
MKAGVPLVQAFEIVAEGLENPAMRDVVLGLKNEVEGGNTFAGALRKYPQYFDNLFCSLIESGEQSGSLEIMLDRVAVYKE
KSEVLKQKIKKAMKYPATVIVVAIVVTIILMVKVVPVFKDLFTSFGADLPAFTQLVVNMSNWMQDYWFILILVIGAAIAG
FLEARKRSKRFRDQLDRLVLRLPIVGDLVYKAIIARYSRTLATTFAAGVPLIDALASTAGATNNTVYEQAVLKIREDVST
GQQLNFAMRVSNRFPTMAIQMVAIGEESGALDEMLDKVANYYESEVDHAVDGLTSMMEPLIMAILGILVGGLVIAMYLPI
FQMGSVV

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=397, Percent_Identity=27.455919395466, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1786295, Length=406, Percent_Identity=27.8325123152709, Blast_Score=169, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 45157; Mature: 45026

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AAKKTQVMPVFAYEGVDRKGIKLKGELPARNMALAKVTLRKQGITIRTIREKRKNIFEG
CCCCCCCCEEHEECCCCCCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LLKKKVKPLDIAIFTRQLATMMKAGVPLVQAFEIVAEGLENPAMRDVVLGLKNEVEGGNT
HHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCH
FAGALRKYPQYFDNLFCSLIESGEQSGSLEIMLDRVAVYKEKSEVLKQKIKKAMKYPATV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IVVAIVVTIILMVKVVPVFKDLFTSFGADLPAFTQLVVNMSNWMQDYWFILILVIGAAIA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFLEARKRSKRFRDQLDRLVLRLPIVGDLVYKAIIARYSRTLATTFAAGVPLIDALASTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
GATNNTVYEQAVLKIREDVSTGQQLNFAMRVSNRFPTMAIQMVAIGEESGALDEMLDKVA
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHEEEEEECCCCCCHHHHHHHHH
NYYESEVDHAVDGLTSMMEPLIMAILGILVGGLVIAMYLPIFQMGSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]