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The map label for this gene is coaE

Identifier: 50083621

GI number: 50083621

Start: 351920

End: 352507

Strand: Reverse

Name: coaE

Synonym: ACIAD0359

Alternate gene names: 50083621

Gene position: 352507-351920 (Counterclockwise)

Preceding gene: 50083622

Following gene: 50083616

Centisome position: 9.8

GC content: 44.05

Gene sequence:

>588_bases
ATGTTTATTGTGGGCCTGACCGGTGGGATTGGTAGCGGTAAATCTGCTGCAAGCCAATGGTTTGAAAAGCAAGGCATACA
GGTAGTAGATGCCGACATTGTGGCGCGTGAAGTGGTCGATGTCGGGCAACCTGCACTCAAAGAGATTGCTACAGCGTTTG
GTGACTGGGTGTTACAAGCAGATGGAAGTCTGAATCGCCGCGCATTAAGAGAGCATATTTTTCAGTCACCAGAATCACGG
CATACGCTTGAAGCTATTACCCATCCCATCATTCGAAAGTCTATTATTGAACAACTCAATGCTGCCACAAGCCCGTATGT
CATTCTGGTTTCTCCACTCTTATTTGAAACTAATCAGCACGAACTGACAGATCGCAACTTACTGATTGATGCTAGTGAAG
AAATTCAAATTGCACGTGCCAGCCAACGAGATGGTCAATCCATCCAGCAGATTCAAAAGATTATTGCGGCACAAATGCCA
AGAGCTGAAAAACAACAACGTGCCGATGATATCGTCCTCAATGATGGGCATTTGAAACATCTTTATCAGCAACTTATAGC
TTTACATGAAAACTATCTGAATCACTAA

Upstream 100 bases:

>100_bases
ATCAGCCTTTTGCATTTGGTCCCTATATCGCGATTGCAGGTTGGATTGCATTTTTGTGGGGCGATCAGATTATGAAAGTC
TACCTGGGAGGCTAAGGATC

Downstream 100 bases:

>100_bases
TCAGATTTCTGCTTTTGTTTCTCCAGCTCAATGGTGAGGGTATCTTTTAGTCGCCAACGCCATGGCTGTAAAGCACCAAT
TCCCATCCCGATCAGACCGC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MFIVGLTGGIGSGKSAASQWFEKQGIQVVDADIVAREVVDVGQPALKEIATAFGDWVLQADGSLNRRALREHIFQSPESR
HTLEAITHPIIRKSIIEQLNAATSPYVILVSPLLFETNQHELTDRNLLIDASEEIQIARASQRDGQSIQQIQKIIAAQMP
RAEKQQRADDIVLNDGHLKHLYQQLIALHENYLNH

Sequences:

>Translated_195_residues
MFIVGLTGGIGSGKSAASQWFEKQGIQVVDADIVAREVVDVGQPALKEIATAFGDWVLQADGSLNRRALREHIFQSPESR
HTLEAITHPIIRKSIIEQLNAATSPYVILVSPLLFETNQHELTDRNLLIDASEEIQIARASQRDGQSIQQIQKIIAAQMP
RAEKQQRADDIVLNDGHLKHLYQQLIALHENYLNH
>Mature_195_residues
MFIVGLTGGIGSGKSAASQWFEKQGIQVVDADIVAREVVDVGQPALKEIATAFGDWVLQADGSLNRRALREHIFQSPESR
HTLEAITHPIIRKSIIEQLNAATSPYVILVSPLLFETNQHELTDRNLLIDASEEIQIARASQRDGQSIQQIQKIIAAQMP
RAEKQQRADDIVLNDGHLKHLYQQLIALHENYLNH

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=193, Percent_Identity=38.3419689119171, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI191252795, Length=193, Percent_Identity=38.3419689119171, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI110227607, Length=162, Percent_Identity=29.0123456790123, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI110227605, Length=162, Percent_Identity=29.0123456790123, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI110227603, Length=162, Percent_Identity=29.0123456790123, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI110227601, Length=162, Percent_Identity=29.0123456790123, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI205277394, Length=162, Percent_Identity=29.0123456790123, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1786292, Length=192, Percent_Identity=45.3125, Blast_Score=167, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17554944, Length=190, Percent_Identity=33.6842105263158, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6320402, Length=193, Percent_Identity=34.7150259067358, Blast_Score=106, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24644728, Length=180, Percent_Identity=37.2222222222222, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24658602, Length=171, Percent_Identity=30.4093567251462, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_ACIAD (Q6FF48)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045131.1
- ProteinModelPortal:   Q6FF48
- SMR:   Q6FF48
- STRING:   Q6FF48
- GeneID:   2877935
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0359
- NMPDR:   fig|62977.3.peg.875
- eggNOG:   COG0237
- HOGENOM:   HBG650290
- OMA:   IIAREVV
- PhylomeDB:   Q6FF48
- ProtClustDB:   PRK00081
- BioCyc:   ASP62977:ACIAD0359-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 21770; Mature: 21770

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS51219 DPCK; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIVGLTGGIGSGKSAASQWFEKQGIQVVDADIVAREVVDVGQPALKEIATAFGDWVLQA
CEEEEECCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEC
DGSLNRRALREHIFQSPESRHTLEAITHPIIRKSIIEQLNAATSPYVILVSPLLFETNQH
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCC
ELTDRNLLIDASEEIQIARASQRDGQSIQQIQKIIAAQMPRAEKQQRADDIVLNDGHLKH
CCCCCCEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHCCCCEEECCCHHHH
LYQQLIALHENYLNH
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MFIVGLTGGIGSGKSAASQWFEKQGIQVVDADIVAREVVDVGQPALKEIATAFGDWVLQA
CEEEEECCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEC
DGSLNRRALREHIFQSPESRHTLEAITHPIIRKSIIEQLNAATSPYVILVSPLLFETNQH
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCC
ELTDRNLLIDASEEIQIARASQRDGQSIQQIQKIIAAQMPRAEKQQRADDIVLNDGHLKH
CCCCCCEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHCCCCEEECCCHHHH
LYQQLIALHENYLNH
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA