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The map label for this gene is pgsA [H]

Identifier: 50083607

GI number: 50083607

Start: 338652

End: 339245

Strand: Direct

Name: pgsA [H]

Synonym: ACIAD0342

Alternate gene names: 50083607

Gene position: 338652-339245 (Clockwise)

Preceding gene: 50083606

Following gene: 50083608

Centisome position: 9.41

GC content: 44.28

Gene sequence:

>594_bases
GTGTCTATGACAACAGGTCGAATCCTGAATATCCCAAATATTTTAACACTTGCACGAATCGCCCTTATTCCTGTTTTTCT
TATAGTGGCATATTGGCCACCTGCAATCGGGGTAAACTTCCATGAAGGAAGCTTTCTGCGGCATCTCGTGCTGACAGCCA
TTTTTATTTTGGCTGCGGTTACAGACTGGTTTGATGGTTATTTGGCGCGAGCTTTAAACCAGACATCGGCTTTTGGCCGT
TTTTTAGATCCTGTGGCAGATAAATTAATGGTGGCTTCGGCACTGATTGTATTGGTGCAGTGGCAACCGACGATCTCCAT
GGCATTTGCTGCAATTGTGATTATCTCACGAGAGATTACAGTTTCTGCATTACGCGAGTGGATGGCAGAACTGGGTGCAA
GAACCAATGTTGCAGTTTCGACCGTAGGTAAATATAAAACAGCTTTCCAGATGATTGCGATTAGCGTCTTCTTATTAAAC
TGGCAGCCCCTGGATCTGCTGGCGTATGCCTTGCTTTACACGGCTGTGATTTTGACTTTATGGTCGATGTTTATTTATCT
GAAAGCAGCTTGGCCTTATCTCAAACAGCCTTAA

Upstream 100 bases:

>100_bases
CGACACTGTGTGACATTTCGTATAAAGTTGGCGTTAGTGAAAAATGCATAAAACCTTAATTAACTAAATTCGCATGATGT
AATTAGGGGACTAACAGGCG

Downstream 100 bases:

>100_bases
GATGTGTAAAAAGCCTTTCAAGTTGAAGGGCTTTTTTATATGTTTAGTGCAAGAATCGGGTCGAAACACGATGCTGGCTC
GTCTACGCTCAACATAAAAT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MSMTTGRILNIPNILTLARIALIPVFLIVAYWPPAIGVNFHEGSFLRHLVLTAIFILAAVTDWFDGYLARALNQTSAFGR
FLDPVADKLMVASALIVLVQWQPTISMAFAAIVIISREITVSALREWMAELGARTNVAVSTVGKYKTAFQMIAISVFLLN
WQPLDLLAYALLYTAVILTLWSMFIYLKAAWPYLKQP

Sequences:

>Translated_197_residues
MSMTTGRILNIPNILTLARIALIPVFLIVAYWPPAIGVNFHEGSFLRHLVLTAIFILAAVTDWFDGYLARALNQTSAFGR
FLDPVADKLMVASALIVLVQWQPTISMAFAAIVIISREITVSALREWMAELGARTNVAVSTVGKYKTAFQMIAISVFLLN
WQPLDLLAYALLYTAVILTLWSMFIYLKAAWPYLKQP
>Mature_196_residues
SMTTGRILNIPNILTLARIALIPVFLIVAYWPPAIGVNFHEGSFLRHLVLTAIFILAAVTDWFDGYLARALNQTSAFGRF
LDPVADKLMVASALIVLVQWQPTISMAFAAIVIISREITVSALREWMAELGARTNVAVSTVGKYKTAFQMIAISVFLLNW
QPLDLLAYALLYTAVILTLWSMFIYLKAAWPYLKQP

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=189, Percent_Identity=46.5608465608466, Blast_Score=149, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6320059, Length=124, Percent_Identity=35.4838709677419, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21994; Mature: 21862

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMTTGRILNIPNILTLARIALIPVFLIVAYWPPAIGVNFHEGSFLRHLVLTAIFILAAV
CCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TDWFDGYLARALNQTSAFGRFLDPVADKLMVASALIVLVQWQPTISMAFAAIVIISREIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VSALREWMAELGARTNVAVSTVGKYKTAFQMIAISVFLLNWQPLDLLAYALLYTAVILTL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
WSMFIYLKAAWPYLKQP
HHHHHHHHHHCHHCCCC
>Mature Secondary Structure 
SMTTGRILNIPNILTLARIALIPVFLIVAYWPPAIGVNFHEGSFLRHLVLTAIFILAAV
CCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TDWFDGYLARALNQTSAFGRFLDPVADKLMVASALIVLVQWQPTISMAFAAIVIISREIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VSALREWMAELGARTNVAVSTVGKYKTAFQMIAISVFLLNWQPLDLLAYALLYTAVILTL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
WSMFIYLKAAWPYLKQP
HHHHHHHHHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]