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The map label for this gene is gph [C]

Identifier: 50083570

GI number: 50083570

Start: 294355

End: 295059

Strand: Direct

Name: gph [C]

Synonym: ACIAD0296

Alternate gene names: 50083570

Gene position: 294355-295059 (Clockwise)

Preceding gene: 50083569

Following gene: 50083571

Centisome position: 8.18

GC content: 41.13

Gene sequence:

>705_bases
ATGCGAAAAGCATGCCTTTACTTTTTTATAAGGTGCAATATGTCTTTAGTACAATTAGAACGTCGTCAACTGGTCTTGTT
TGATCTAGATGGAACATTGGTCGATACAGCATCAGATATGTATCGTGCGATGAATCTGACTTTGGATCATCTGGGGTGGT
CTCGTGTTACAGAAGCTCAAATTCGCCAATGGGTTGGACAGGGTACTGGCAAGTTATGCGATGCAGTTTTAAAACATTTG
TTTGAAGAAGTAGAACCTGCAAAGCATCAAATGCTGTTAACCACTTATCTCGAAATTTATGCACAAGAGTTGTGTGTGAC
CAGTCGCTTATTTGAAGGTGTGCAAGCATTTCTTGATGAGTGTAAGGCGCGTAAAATCGAGATGGCTTGTGTAACCAACA
AGCCTGAGCAATTGGCGAGAAATTTATTGGAAACACTTAAGATTGGCGATTACTTTGACTTGGTCGTGGGTGGGGATACT
TTGCCTGTACGAAAACCAGACCCGCTTCCATTGCTACATAGTGTGCAGGTGATGAAGACCACTATTGAGAATACCTTGAT
GATCGGTGATTCAAAAAATGATGTTGAAGCAGCCAGACGTGCGGGTATCGATTGTATTGTAGTCAGCTATGGCTATAATC
ATGGAGAAAATATTTATGATAGTCATCCGCAAGAAGTTGTGGATCGTCTGGATCAATTGATTTAA

Upstream 100 bases:

>100_bases
TGTTGGGCTGTTTACAATTATTACACTCATTATTCTTGCTGTAGTCGCTTGGTTGTTTTTTAAATAATCTTGCCTGAGCT
AGACAAACGTCTGTAAAGGC

Downstream 100 bases:

>100_bases
TCATTGAGGAGTGGGGAATGTATCACCTTATGGTTTTTCGATGGCGATAATCGCGTCTTAAATCACCTTTATCGTACTTA
ACTTAAAACCATCGAGAATA

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MRKACLYFFIRCNMSLVQLERRQLVLFDLDGTLVDTASDMYRAMNLTLDHLGWSRVTEAQIRQWVGQGTGKLCDAVLKHL
FEEVEPAKHQMLLTTYLEIYAQELCVTSRLFEGVQAFLDECKARKIEMACVTNKPEQLARNLLETLKIGDYFDLVVGGDT
LPVRKPDPLPLLHSVQVMKTTIENTLMIGDSKNDVEAARRAGIDCIVVSYGYNHGENIYDSHPQEVVDRLDQLI

Sequences:

>Translated_234_residues
MRKACLYFFIRCNMSLVQLERRQLVLFDLDGTLVDTASDMYRAMNLTLDHLGWSRVTEAQIRQWVGQGTGKLCDAVLKHL
FEEVEPAKHQMLLTTYLEIYAQELCVTSRLFEGVQAFLDECKARKIEMACVTNKPEQLARNLLETLKIGDYFDLVVGGDT
LPVRKPDPLPLLHSVQVMKTTIENTLMIGDSKNDVEAARRAGIDCIVVSYGYNHGENIYDSHPQEVVDRLDQLI
>Mature_234_residues
MRKACLYFFIRCNMSLVQLERRQLVLFDLDGTLVDTASDMYRAMNLTLDHLGWSRVTEAQIRQWVGQGTGKLCDAVLKHL
FEEVEPAKHQMLLTTYLEIYAQELCVTSRLFEGVQAFLDECKARKIEMACVTNKPEQLARNLLETLKIGDYFDLVVGGDT
LPVRKPDPLPLLHSVQVMKTTIENTLMIGDSKNDVEAARRAGIDCIVVSYGYNHGENIYDSHPQEVVDRLDQLI

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=227, Percent_Identity=33.0396475770925, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 26654; Mature: 26654

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKACLYFFIRCNMSLVQLERRQLVLFDLDGTLVDTASDMYRAMNLTLDHLGWSRVTEAQ
CCHHHEEHHHHCCHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IRQWVGQGTGKLCDAVLKHLFEEVEPAKHQMLLTTYLEIYAQELCVTSRLFEGVQAFLDE
HHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CKARKIEMACVTNKPEQLARNLLETLKIGDYFDLVVGGDTLPVRKPDPLPLLHSVQVMKT
HHHCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
TIENTLMIGDSKNDVEAARRAGIDCIVVSYGYNHGENIYDSHPQEVVDRLDQLI
HHHHEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRKACLYFFIRCNMSLVQLERRQLVLFDLDGTLVDTASDMYRAMNLTLDHLGWSRVTEAQ
CCHHHEEHHHHCCHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IRQWVGQGTGKLCDAVLKHLFEEVEPAKHQMLLTTYLEIYAQELCVTSRLFEGVQAFLDE
HHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CKARKIEMACVTNKPEQLARNLLETLKIGDYFDLVVGGDTLPVRKPDPLPLLHSVQVMKT
HHHCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
TIENTLMIGDSKNDVEAARRAGIDCIVVSYGYNHGENIYDSHPQEVVDRLDQLI
HHHHEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA