Click here to switch to the map view.

The map label for this gene is comM [H]

Identifier: 50083520

GI number: 50083520

Start: 242202

End: 243689

Strand: Reverse

Name: comM [H]

Synonym: ACIAD0242

Alternate gene names: 50083520

Gene position: 243689-242202 (Counterclockwise)

Preceding gene: 50083521

Following gene: 50083518

Centisome position: 6.77

GC content: 44.15

Gene sequence:

>1488_bases
ATGTCCTTTGCAAAAATTTTTACGCGGGGTGTTTTGGGTTTACACGCACCACAAATTGAAGTTGAAGTTCATTTAAGTCA
AGGACTTCCTTCACTGACTATCGTTGGATTACCCGAAGCCGCGGTCCGTGAAAGTAAAGATCGTGTTCGTTCTGCCATCA
TCAATAGTGGTTTTCAATTCCCGACCAAGCGCCTAACCATTAATTTAGCACCAGCCGATCTGCCCAAAGATGGTTCACGT
CTGGATCTTCCTATTGCCTTGGGTATTTTAATTGCTTCAGGTCAGTTACCTGAAGGTTGTACAGATCAATATGAACTGAT
TGGTGAACTGGCTTTAGACGGTCATTTACGCCCAGTCACCAGTGCATTGACTATTGCCATCGCATGTCAACAAGCCAAAC
ATCAATTAATTGCACCTGATGAAAATGGCCAAGAGATTGGCCAGCTTCCTGATTTTTCTTCATATACTGCTGCCCATTTA
AAACAGGTATGTGAGCATTTTTTAAAGATCACACTGCTCTCTCCAAATAAAACTGCTGTTTTAAATACGCAACATCGCTA
TTCACTGGATCTGGCTGATGTCAAAGGTCAGCTTCGTCCAAGACGCGCTCTTGAGATCGCTGCGGCTGGTGGGCATTCAT
TACTTTTTCGTGGGCCACCTGGAACAGGAAAAACATTGCTGGCTTCTCGCTTACCGAGTATTTTGCCACCGCTTACCCCT
CAAGAGAATCTTGAAGTAGCGAGTATCTATTCTATCGCCAATACCTCTCATCCTTTTGGGCTTCGACCATTTAGGGCACC
CCATCATACAGCTTCGGCTATTGCTTTAGTGGGAGGGGGTTCAAATCCAAAACCAGGTGAAATTACCTTATCGCATTTAG
GCGTTTTATTTTTGGACGAACTTCCAGAATTTGATCGCAAAGTTCTTGAAGTATTGCGTCAACCCTTAGAAGCGAAGGAA
ATTACTATTTCGCGGGCAGCCCGTCAGATTTCTTTTCCTGCAAACTTTCAGTTAATTGCTGCCATGAATCCTTGTCCGTG
TGGCTATGCCTTTAGTCAGGATCAACGTTGTCAGTGTACTCCAGAAGCCATTCGTCGTTATCAGGCTCGAATTTCTGGTC
CATTATTAGATCGAATTGACTTACACATTGATGTACCACCATTACAGGCCAACGAATTACAAAGTACAGCCCCTACTGAA
AATTCTGCCAGTGTAAGAGTGCGTGTAGAAAATGCCTATACGTACCAAATCAAACGACAAAACTGTTTAAATCAAGCACT
CACGCCACGACAGCTTGAAGAAATAGCCCAGCTTAGTCCTGCTTCTCAGAAAATTATGGCTCTTGCCCAGCAAAAGCTCA
ATCTGTCAGCACGCTCCTATCATCGGATTTTACGCGTTGCACGCACCATTGCCGATCTGGAACAGAGCCCTGAGATTGAG
CGTCATCATTTAAATGAAGCCTTATCCTATCGCAGTGAACATAGCTAA

Upstream 100 bases:

>100_bases
ACTTGAACAACAGATTCATAATAAAAAATAAGCACTCTTTTAGCGCATTTTTATACTTTATACCTATTCTAAAAAAGCAC
CATAATGGAACAATAATAGT

Downstream 100 bases:

>100_bases
AATAAAAAAGACCGTTTTAATAAAACGGTCTTTTCAAATCAATCAATAACAAAATTTTATGTTAAAAATTAGAATGTTTT
AGACAACGTAAATACAGCAC

Product: magnesium chelatase, competence related protein (ComM)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSFAKIFTRGVLGLHAPQIEVEVHLSQGLPSLTIVGLPEAAVRESKDRVRSAIINSGFQFPTKRLTINLAPADLPKDGSR
LDLPIALGILIASGQLPEGCTDQYELIGELALDGHLRPVTSALTIAIACQQAKHQLIAPDENGQEIGQLPDFSSYTAAHL
KQVCEHFLKITLLSPNKTAVLNTQHRYSLDLADVKGQLRPRRALEIAAAGGHSLLFRGPPGTGKTLLASRLPSILPPLTP
QENLEVASIYSIANTSHPFGLRPFRAPHHTASAIALVGGGSNPKPGEITLSHLGVLFLDELPEFDRKVLEVLRQPLEAKE
ITISRAARQISFPANFQLIAAMNPCPCGYAFSQDQRCQCTPEAIRRYQARISGPLLDRIDLHIDVPPLQANELQSTAPTE
NSASVRVRVENAYTYQIKRQNCLNQALTPRQLEEIAQLSPASQKIMALAQQKLNLSARSYHRILRVARTIADLEQSPEIE
RHHLNEALSYRSEHS

Sequences:

>Translated_495_residues
MSFAKIFTRGVLGLHAPQIEVEVHLSQGLPSLTIVGLPEAAVRESKDRVRSAIINSGFQFPTKRLTINLAPADLPKDGSR
LDLPIALGILIASGQLPEGCTDQYELIGELALDGHLRPVTSALTIAIACQQAKHQLIAPDENGQEIGQLPDFSSYTAAHL
KQVCEHFLKITLLSPNKTAVLNTQHRYSLDLADVKGQLRPRRALEIAAAGGHSLLFRGPPGTGKTLLASRLPSILPPLTP
QENLEVASIYSIANTSHPFGLRPFRAPHHTASAIALVGGGSNPKPGEITLSHLGVLFLDELPEFDRKVLEVLRQPLEAKE
ITISRAARQISFPANFQLIAAMNPCPCGYAFSQDQRCQCTPEAIRRYQARISGPLLDRIDLHIDVPPLQANELQSTAPTE
NSASVRVRVENAYTYQIKRQNCLNQALTPRQLEEIAQLSPASQKIMALAQQKLNLSARSYHRILRVARTIADLEQSPEIE
RHHLNEALSYRSEHS
>Mature_494_residues
SFAKIFTRGVLGLHAPQIEVEVHLSQGLPSLTIVGLPEAAVRESKDRVRSAIINSGFQFPTKRLTINLAPADLPKDGSRL
DLPIALGILIASGQLPEGCTDQYELIGELALDGHLRPVTSALTIAIACQQAKHQLIAPDENGQEIGQLPDFSSYTAAHLK
QVCEHFLKITLLSPNKTAVLNTQHRYSLDLADVKGQLRPRRALEIAAAGGHSLLFRGPPGTGKTLLASRLPSILPPLTPQ
ENLEVASIYSIANTSHPFGLRPFRAPHHTASAIALVGGGSNPKPGEITLSHLGVLFLDELPEFDRKVLEVLRQPLEAKEI
TISRAARQISFPANFQLIAAMNPCPCGYAFSQDQRCQCTPEAIRRYQARISGPLLDRIDLHIDVPPLQANELQSTAPTEN
SASVRVRVENAYTYQIKRQNCLNQALTPRQLEEIAQLSPASQKIMALAQQKLNLSARSYHRILRVARTIADLEQSPEIER
HHLNEALSYRSEHS

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=498, Percent_Identity=48.995983935743, Blast_Score=453, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 54269; Mature: 54138

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFAKIFTRGVLGLHAPQIEVEVHLSQGLPSLTIVGLPEAAVRESKDRVRSAIINSGFQF
CCHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCC
PTKRLTINLAPADLPKDGSRLDLPIALGILIASGQLPEGCTDQYELIGELALDGHLRPVT
CCEEEEEEECCCCCCCCCCEECHHHEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHH
SALTIAIACQQAKHQLIAPDENGQEIGQLPDFSSYTAAHLKQVCEHFLKITLLSPNKTAV
HHHHHHHHHHHHCCCEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCEEE
LNTQHRYSLDLADVKGQLRPRRALEIAAAGGHSLLFRGPPGTGKTLLASRLPSILPPLTP
EECCCCEEEEHHHHCCCCCCCHHEEEEECCCCEEEEECCCCCCHHHHHHHCHHHCCCCCC
QENLEVASIYSIANTSHPFGLRPFRAPHHTASAIALVGGGSNPKPGEITLSHLGVLFLDE
CCCCCCEEEEEHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHH
LPEFDRKVLEVLRQPLEAKEITISRAARQISFPANFQLIAAMNPCPCGYAFSQDQRCQCT
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
PEAIRRYQARISGPLLDRIDLHIDVPPLQANELQSTAPTENSASVRVRVENAYTYQIKRQ
HHHHHHHHHHHCCCCCCEEEEEEECCCCCHHCCCCCCCCCCCCEEEEEEECEEEEEEEHH
NCLNQALTPRQLEEIAQLSPASQKIMALAQQKLNLSARSYHRILRVARTIADLEQSPEIE
HHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHH
RHHLNEALSYRSEHS
HHHHHHHHHHCCCCC
>Mature Secondary Structure 
SFAKIFTRGVLGLHAPQIEVEVHLSQGLPSLTIVGLPEAAVRESKDRVRSAIINSGFQF
CHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCC
PTKRLTINLAPADLPKDGSRLDLPIALGILIASGQLPEGCTDQYELIGELALDGHLRPVT
CCEEEEEEECCCCCCCCCCEECHHHEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHH
SALTIAIACQQAKHQLIAPDENGQEIGQLPDFSSYTAAHLKQVCEHFLKITLLSPNKTAV
HHHHHHHHHHHHCCCEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCEEE
LNTQHRYSLDLADVKGQLRPRRALEIAAAGGHSLLFRGPPGTGKTLLASRLPSILPPLTP
EECCCCEEEEHHHHCCCCCCCHHEEEEECCCCEEEEECCCCCCHHHHHHHCHHHCCCCCC
QENLEVASIYSIANTSHPFGLRPFRAPHHTASAIALVGGGSNPKPGEITLSHLGVLFLDE
CCCCCCEEEEEHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHH
LPEFDRKVLEVLRQPLEAKEITISRAARQISFPANFQLIAAMNPCPCGYAFSQDQRCQCT
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
PEAIRRYQARISGPLLDRIDLHIDVPPLQANELQSTAPTENSASVRVRVENAYTYQIKRQ
HHHHHHHHHHHCCCCCCEEEEEEECCCCCHHCCCCCCCCCCCCEEEEEEECEEEEEEEHH
NCLNQALTPRQLEEIAQLSPASQKIMALAQQKLNLSARSYHRILRVARTIADLEQSPEIE
HHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHH
RHHLNEALSYRSEHS
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]