Click here to switch to the map view.

The map label for this gene is atpC

Identifier: 50083470

GI number: 50083470

Start: 185297

End: 185716

Strand: Direct

Name: atpC

Synonym: ACIAD0188

Alternate gene names: 50083470

Gene position: 185297-185716 (Clockwise)

Preceding gene: 50083469

Following gene: 50083471

Centisome position: 5.15

GC content: 45.71

Gene sequence:

>420_bases
ATGGCGACGATGCAATGTGATGTCGTAAGTGTGAAAGAGTCAATTTACTCTGGACAAGTTACGATGTTGATCGCGAAAGG
TGCAGGTGGTGAGTTGGGTATTTTACCTGGACACGCGCCACTGGTAACCTTGCTCCAACCAGGACCGATCCGCGTTCAGT
TGGAAAATGGTACAGAAGAAATCGTGTATGTATCAGGCGGTGTGTTAGAAGTTCAGCCTCATGTTGTGACTGTGCTTGCA
GATACTGCAATCCGTGCAGACAATTTGGATGAAGCTGCAATTTTAGAAGCACGTAAAAATGCTGAACAATTGCTTGCAAA
CCAAAAGAGTGATTTGGACTCAGCTGCTGCTTTGGCATCTCTATCAGAGATCTCAGGTCAGCTCGAAACGATCCGCAAAA
TCAAAAATCGCGCGCTTTAA

Upstream 100 bases:

>100_bases
TCACATCCCAGAACAAGCGTTCTACATGGTGGGTGGTATTGACGAAGTAATTGCTAAAGCTGAGAAACTTTAATTAGCAA
CTCTAATTTAGGAGGTTCTC

Downstream 100 bases:

>100_bases
GCCAAGATTTAAGATTGAAAAAGCCACCGTCAGGTGGCTTTTTTTTGTATAAAATAAAATATGTAGAAAGTATTTATTTT
TTGTAATTTTAATGTAAATT

Product: F0F1 ATP synthase subunit epsilon

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F1 sector epsilon subunit; F-ATPase epsilon subunit

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MATMQCDVVSVKESIYSGQVTMLIAKGAGGELGILPGHAPLVTLLQPGPIRVQLENGTEEIVYVSGGVLEVQPHVVTVLA
DTAIRADNLDEAAILEARKNAEQLLANQKSDLDSAAALASLSEISGQLETIRKIKNRAL

Sequences:

>Translated_139_residues
MATMQCDVVSVKESIYSGQVTMLIAKGAGGELGILPGHAPLVTLLQPGPIRVQLENGTEEIVYVSGGVLEVQPHVVTVLA
DTAIRADNLDEAAILEARKNAEQLLANQKSDLDSAAALASLSEISGQLETIRKIKNRAL
>Mature_138_residues
ATMQCDVVSVKESIYSGQVTMLIAKGAGGELGILPGHAPLVTLLQPGPIRVQLENGTEEIVYVSGGVLEVQPHVVTVLAD
TAIRADNLDEAAILEARKNAEQLLANQKSDLDSAAALASLSEISGQLETIRKIKNRAL

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG0355

COG function: function code C; F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase epsilon chain family

Homologues:

Organism=Escherichia coli, GI1790169, Length=134, Percent_Identity=48.5074626865672, Blast_Score=130, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPE_ACIAD (Q6FFJ9)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_044980.1
- ProteinModelPortal:   Q6FFJ9
- SMR:   Q6FFJ9
- STRING:   Q6FFJ9
- GeneID:   2878478
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0188
- NMPDR:   fig|62977.3.peg.275
- eggNOG:   COG0355
- HOGENOM:   HBG663981
- OMA:   MAMTVHC
- PhylomeDB:   Q6FFJ9
- ProtClustDB:   PRK00571
- BioCyc:   ASP62977:ACIAD0188-MONOMER
- HAMAP:   MF_00530
- InterPro:   IPR001469
- InterPro:   IPR020547
- InterPro:   IPR020546
- Gene3D:   G3DSA:1.20.5.440
- Gene3D:   G3DSA:2.60.15.10
- PANTHER:   PTHR13822
- ProDom:   PD000944
- TIGRFAMs:   TIGR01216

Pfam domain/function: PF02823 ATP-synt_DE_N; SSF46604 ATPsynt_DE; SSF51344 ATPsynt_DE

EC number: 3.6.3.14

Molecular weight: Translated: 14642; Mature: 14511

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATMQCDVVSVKESIYSGQVTMLIAKGAGGELGILPGHAPLVTLLQPGPIRVQLENGTEE
CCCCCCHHHHHHHHHCCCEEEEEEEECCCCCEEEECCCCCEEEEECCCCEEEEECCCCCE
IVYVSGGVLEVQPHVVTVLADTAIRADNLDEAAILEARKNAEQLLANQKSDLDSAAALAS
EEEEECCEEEECCEEEEEEECCEECCCCCCHHHHHHHHCCHHHHHHCCCCCHHHHHHHHH
LSEISGQLETIRKIKNRAL
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATMQCDVVSVKESIYSGQVTMLIAKGAGGELGILPGHAPLVTLLQPGPIRVQLENGTEE
CCCCCHHHHHHHHHCCCEEEEEEEECCCCCEEEECCCCCEEEEECCCCEEEEECCCCCE
IVYVSGGVLEVQPHVVTVLADTAIRADNLDEAAILEARKNAEQLLANQKSDLDSAAALAS
EEEEECCEEEECCEEEEEEECCEECCCCCCHHHHHHHHCCHHHHHHCCCCCHHHHHHHHH
LSEISGQLETIRKIKNRAL
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA