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The map label for this gene is ccpA [H]

Identifier: 50083423

GI number: 50083423

Start: 139127

End: 140170

Strand: Direct

Name: ccpA [H]

Synonym: ACIAD0135

Alternate gene names: 50083423

Gene position: 139127-140170 (Clockwise)

Preceding gene: 50083422

Following gene: 50083424

Centisome position: 3.87

GC content: 36.4

Gene sequence:

>1044_bases
ATGCAAAGTAACGTTAATAAAAAAACTATAACTATAAGTGATGTAGCGCTTGCTGCTCAGGTTTCTCGAACGACAGTATC
TCATGCCCTAAATGGTAAAGGTGAAGTTAACCCTGATACAAGAAAAAAAATTCAGGAAATCGCGGAGCAATTAGGATATC
GTCCAAACCGATTTGCAAAAGCTTTACGAAGTGGAGGTACTAAGACAATCGCCTTAATTTCGACTATTCCAAGTGCTATT
TCTGGTGGCGCATCTAAGTTGGGTTTTATGATGGAAGTGGCGAATGTCGCAGCAATTTATGCTTTAGAGCATGATTTGTA
TATCTTGTTAGTGCCTTTTATTGATCATAATAATTTCGATGGTAATTTAATGAATGTTGATGGCGTTATTTTACTTGAGC
CATGCCTGAATGATCCAATAGTTAAAAAATTACTACAGTATAAAATTCCATTGGTATGTATAGGTACACCTGGTCAAGAT
AATAAAGAAGTCCCTTATGTCGATTTGCAGTCCGAACAAACTGCTATAAAACTACTTGAACATCTAGTTGAGGAAGGTGC
TCATCAGATTGCATTAATTACTGGTCAATCCAAACGGAATGCGTCTCTAAAGGCTGAAGAGATTTATAGTCAATATTGTC
AACAGTATGCTATGACTGAAGTCGTGTATAAGGTTGAAGAGCATTTAGGTGAGATGGGCGGAAAATCTGCAATAGCAGAA
ATTATGAAACAATATCCAAAAACGGATGCTATTTTAGTAATGATTGATACTTTTGCTACTGGTGTGATGCAATATTTAAC
TGAGAAGGGAATATCGGTACCCAAACAAATGAAGGTAGTCACACGATATAATGGAATTCGTGCATTAACCTCAAATCCCC
CTCTTACGGCTGTTGATCTACATCTTGATGATGTAGCTAAAATAGCAATTGATTTACTAATAACACAGTTAAACGAAGAT
ATCGAAACAGGATCTTTACGAGTCATGCCAGCACCAGAAATTATAAAACGCACATCAAGTGTGCAAATATCATCTTCGAA
TTAA

Upstream 100 bases:

>100_bases
TGAATTGTTGGCTTAAGTAGGGTTGGGGTTAAATATAGACACTGTTTTTTCGGTTATACTTAGAATAATTTTAATATTCA
GATATTATTTGGCCCTAAAA

Downstream 100 bases:

>100_bases
AATTAGGGTAAATTATTAGAAAACATAGGCTCATATTCTTTTTATATAAGATAATTAAATACAGATTTTTTTATTCAATA
AAATTTTAAATAAAAACAAA

Product: GalR/LacI family transcriptional repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MQSNVNKKTITISDVALAAQVSRTTVSHALNGKGEVNPDTRKKIQEIAEQLGYRPNRFAKALRSGGTKTIALISTIPSAI
SGGASKLGFMMEVANVAAIYALEHDLYILLVPFIDHNNFDGNLMNVDGVILLEPCLNDPIVKKLLQYKIPLVCIGTPGQD
NKEVPYVDLQSEQTAIKLLEHLVEEGAHQIALITGQSKRNASLKAEEIYSQYCQQYAMTEVVYKVEEHLGEMGGKSAIAE
IMKQYPKTDAILVMIDTFATGVMQYLTEKGISVPKQMKVVTRYNGIRALTSNPPLTAVDLHLDDVAKIAIDLLITQLNED
IETGSLRVMPAPEIIKRTSSVQISSSN

Sequences:

>Translated_347_residues
MQSNVNKKTITISDVALAAQVSRTTVSHALNGKGEVNPDTRKKIQEIAEQLGYRPNRFAKALRSGGTKTIALISTIPSAI
SGGASKLGFMMEVANVAAIYALEHDLYILLVPFIDHNNFDGNLMNVDGVILLEPCLNDPIVKKLLQYKIPLVCIGTPGQD
NKEVPYVDLQSEQTAIKLLEHLVEEGAHQIALITGQSKRNASLKAEEIYSQYCQQYAMTEVVYKVEEHLGEMGGKSAIAE
IMKQYPKTDAILVMIDTFATGVMQYLTEKGISVPKQMKVVTRYNGIRALTSNPPLTAVDLHLDDVAKIAIDLLITQLNED
IETGSLRVMPAPEIIKRTSSVQISSSN
>Mature_347_residues
MQSNVNKKTITISDVALAAQVSRTTVSHALNGKGEVNPDTRKKIQEIAEQLGYRPNRFAKALRSGGTKTIALISTIPSAI
SGGASKLGFMMEVANVAAIYALEHDLYILLVPFIDHNNFDGNLMNVDGVILLEPCLNDPIVKKLLQYKIPLVCIGTPGQD
NKEVPYVDLQSEQTAIKLLEHLVEEGAHQIALITGQSKRNASLKAEEIYSQYCQQYAMTEVVYKVEEHLGEMGGKSAIAE
IMKQYPKTDAILVMIDTFATGVMQYLTEKGISVPKQMKVVTRYNGIRALTSNPPLTAVDLHLDDVAKIAIDLLITQLNED
IETGSLRVMPAPEIIKRTSSVQISSSN

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes and in the positive regulation of genes involved in excretion of excess carbon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787580, Length=315, Percent_Identity=25.7142857142857, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1787948, Length=349, Percent_Identity=25.5014326647564, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787906, Length=277, Percent_Identity=29.2418772563177, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790369, Length=349, Percent_Identity=22.6361031518625, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786540, Length=350, Percent_Identity=26, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790194, Length=321, Percent_Identity=25.8566978193146, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790689, Length=274, Percent_Identity=25.1824817518248, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789456, Length=321, Percent_Identity=23.3644859813084, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37992; Mature: 37992

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2 ; PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSNVNKKTITISDVALAAQVSRTTVSHALNGKGEVNPDTRKKIQEIAEQLGYRPNRFAK
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHH
ALRSGGTKTIALISTIPSAISGGASKLGFMMEVANVAAIYALEHDLYILLVPFIDHNNFD
HHHCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCEEEEEEEEECCCCCC
GNLMNVDGVILLEPCLNDPIVKKLLQYKIPLVCIGTPGQDNKEVPYVDLQSEQTAIKLLE
CCEEECCCEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCEEECCCHHHHHHHHH
HLVEEGAHQIALITGQSKRNASLKAEEIYSQYCQQYAMTEVVYKVEEHLGEMGGKSAIAE
HHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
IMKQYPKTDAILVMIDTFATGVMQYLTEKGISVPKQMKVVTRYNGIRALTSNPPLTAVDL
HHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEECCCCCEEEEEE
HLDDVAKIAIDLLITQLNEDIETGSLRVMPAPEIIKRTSSVQISSSN
CHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHCCCCEEEECCC
>Mature Secondary Structure
MQSNVNKKTITISDVALAAQVSRTTVSHALNGKGEVNPDTRKKIQEIAEQLGYRPNRFAK
CCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHH
ALRSGGTKTIALISTIPSAISGGASKLGFMMEVANVAAIYALEHDLYILLVPFIDHNNFD
HHHCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCEEEEEEEEECCCCCC
GNLMNVDGVILLEPCLNDPIVKKLLQYKIPLVCIGTPGQDNKEVPYVDLQSEQTAIKLLE
CCEEECCCEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCEEECCCHHHHHHHHH
HLVEEGAHQIALITGQSKRNASLKAEEIYSQYCQQYAMTEVVYKVEEHLGEMGGKSAIAE
HHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
IMKQYPKTDAILVMIDTFATGVMQYLTEKGISVPKQMKVVTRYNGIRALTSNPPLTAVDL
HHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEECCCCCEEEEEE
HLDDVAKIAIDLLITQLNEDIETGSLRVMPAPEIIKRTSSVQISSSN
CHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8878037 [H]