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The map label for this gene is mviN [H]

Identifier: 50083358

GI number: 50083358

Start: 60933

End: 62480

Strand: Direct

Name: mviN [H]

Synonym: ACIAD0064

Alternate gene names: 50083358

Gene position: 60933-62480 (Clockwise)

Preceding gene: 50083357

Following gene: 50083364

Centisome position: 1.69

GC content: 46.06

Gene sequence:

>1548_bases
ATGGCATTGTGGCGATCGACGTTTATTGTCAGTGCAATGACGATGTTATCTCGAGTATTGGGTTTGGTCCGCGATATGGT
CTTACTCAATGTTTTTGGGGCAGGGAAGGACTTCGATACATTTGTAGTGGCGTTTCGGATTCCTAACTTTTTTAGGCGAC
TGTTTGCCGAAGGGGCATTTTCCCAAGCATTTATTCCTGTGCTCACCGAATATAAATCGGGACGTGCACATGCAGAAGTC
CAGATTCTGATTAGTCGGGTATTTGGATGCTTGCTCATGGTGATGAGCCTGCTCACCCTGATTGCCATGATTATTGCACC
TGTCATTATTTACGCCTATGCACCAGGTTTTCATAACGATCCTGAAAAGTTTGATCTGGCCGTCGGGATGTTTCGCCTGA
CTATTCCGTACCTCATGTTTATGTCGCTGACTGCATTTGCCAGCAGTATTCTCAATAGTTACGGCTCTTTTGCCTCTCCT
GCATTTTCACCTGTACTGCTCAATGTGGCCATGATTGCGGGCGCATGGTGGCTCACACCGTATATGCAACAGCCGATTAT
GGCTTTGGGGTGGGCCGTACTAGGTGCGGGGATCTTACAGCTTGCGATTCAGATTCCAGAATTGTGGCGTAAAAAACTGT
TGATTCCACCCAAGGTCGATTTTAAGCATGAAGGCGTAGAACGCATTATGAAGCTGATGCTACCAGCATTGTTTGGTGTA
TCGGTAACCCAGATTAATCTCTTGCTAAATACCATTTGGGCCTCGTTTATGCAGGATGGCTCAGTTTCGTGGCTATACAG
TGCAGAACGTATGACCGAATTACCCTTAGGCTTGATTGGGGTGGCGATTGGTACCGTGATTTTACCTTCATTGTCTATGC
GTCATGCAGAGCAAGATCAGGAAAAATTCCGTGGTATGCTGGATTGGGCAGCGCGTGTCATTGTCTTGGTGGGTTTACCT
GCGAGTATTGCGCTGTTTATGTTGTCGACCCCAATTATTCAGGCTTTATTTCAGCGTGGCGAGTTTACTTGGGAAGATAC
CAGAATGACTGCGCTTGCACTGCAATGTATGAGCGCGGGTGTGATTGCATTTATGCTGATTAAGGTTTTTGCGCCTGGTT
TTTATGCCCAGCAGGATACCAAGACTCCAGTGCGTGTCGGGCTGATCGCAGTTGCTGCCAATGCTCTGTTAAACGTGATA
TTTATTGGTTTCTTTAAACTGATCGATTGGCAAGCGGAGCACATGGCTTTAGCGCTGTCATCTTCTGGCTCTGCTTTGGT
GAATGCGGGTTTACTCTATTTTTATTTGCATAAGCGAAATATTTTTCGTTTTGGCGCACATTGGAAGAAACTGGCAATTC
AATATGCGATAGCCAATCTTGCCATGATTGCAGCGCTATGGGCTGCATTACACTGGTACGATGGACAGTCTTCACAGTGG
ATGCGCATTATTGAAGTGATTGCATTTTGTGTTATTGGTGTTGCTGCATATGGTATTGCATTATTTGCAGCAGGCTTTCG
CCCACGCCACTTAAAACATGAGGCATAA

Upstream 100 bases:

>100_bases
CTCGACTCAAAAAAAACTGAATTTGGACATGATTTCGCAACGAAATAATCTGCAACTTTCATTACAATATCGACTTTGTG
TTTAGCCGTAGGTAGAGACG

Downstream 100 bases:

>100_bases
ATAAAGCAACGCTTTATTTATGCCGCAAGACAAGCGAAGCGCGTAGATAACAAAAGCAACGCTTTATTTATGCCGCAAGA
CAAGCGAAGCGCGTAGATAA

Product: MviN family virulence factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MALWRSTFIVSAMTMLSRVLGLVRDMVLLNVFGAGKDFDTFVVAFRIPNFFRRLFAEGAFSQAFIPVLTEYKSGRAHAEV
QILISRVFGCLLMVMSLLTLIAMIIAPVIIYAYAPGFHNDPEKFDLAVGMFRLTIPYLMFMSLTAFASSILNSYGSFASP
AFSPVLLNVAMIAGAWWLTPYMQQPIMALGWAVLGAGILQLAIQIPELWRKKLLIPPKVDFKHEGVERIMKLMLPALFGV
SVTQINLLLNTIWASFMQDGSVSWLYSAERMTELPLGLIGVAIGTVILPSLSMRHAEQDQEKFRGMLDWAARVIVLVGLP
ASIALFMLSTPIIQALFQRGEFTWEDTRMTALALQCMSAGVIAFMLIKVFAPGFYAQQDTKTPVRVGLIAVAANALLNVI
FIGFFKLIDWQAEHMALALSSSGSALVNAGLLYFYLHKRNIFRFGAHWKKLAIQYAIANLAMIAALWAALHWYDGQSSQW
MRIIEVIAFCVIGVAAYGIALFAAGFRPRHLKHEA

Sequences:

>Translated_515_residues
MALWRSTFIVSAMTMLSRVLGLVRDMVLLNVFGAGKDFDTFVVAFRIPNFFRRLFAEGAFSQAFIPVLTEYKSGRAHAEV
QILISRVFGCLLMVMSLLTLIAMIIAPVIIYAYAPGFHNDPEKFDLAVGMFRLTIPYLMFMSLTAFASSILNSYGSFASP
AFSPVLLNVAMIAGAWWLTPYMQQPIMALGWAVLGAGILQLAIQIPELWRKKLLIPPKVDFKHEGVERIMKLMLPALFGV
SVTQINLLLNTIWASFMQDGSVSWLYSAERMTELPLGLIGVAIGTVILPSLSMRHAEQDQEKFRGMLDWAARVIVLVGLP
ASIALFMLSTPIIQALFQRGEFTWEDTRMTALALQCMSAGVIAFMLIKVFAPGFYAQQDTKTPVRVGLIAVAANALLNVI
FIGFFKLIDWQAEHMALALSSSGSALVNAGLLYFYLHKRNIFRFGAHWKKLAIQYAIANLAMIAALWAALHWYDGQSSQW
MRIIEVIAFCVIGVAAYGIALFAAGFRPRHLKHEA
>Mature_514_residues
ALWRSTFIVSAMTMLSRVLGLVRDMVLLNVFGAGKDFDTFVVAFRIPNFFRRLFAEGAFSQAFIPVLTEYKSGRAHAEVQ
ILISRVFGCLLMVMSLLTLIAMIIAPVIIYAYAPGFHNDPEKFDLAVGMFRLTIPYLMFMSLTAFASSILNSYGSFASPA
FSPVLLNVAMIAGAWWLTPYMQQPIMALGWAVLGAGILQLAIQIPELWRKKLLIPPKVDFKHEGVERIMKLMLPALFGVS
VTQINLLLNTIWASFMQDGSVSWLYSAERMTELPLGLIGVAIGTVILPSLSMRHAEQDQEKFRGMLDWAARVIVLVGLPA
SIALFMLSTPIIQALFQRGEFTWEDTRMTALALQCMSAGVIAFMLIKVFAPGFYAQQDTKTPVRVGLIAVAANALLNVIF
IGFFKLIDWQAEHMALALSSSGSALVNAGLLYFYLHKRNIFRFGAHWKKLAIQYAIANLAMIAALWAALHWYDGQSSQWM
RIIEVIAFCVIGVAAYGIALFAAGFRPRHLKHEA

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family [H]

Homologues:

Organism=Escherichia coli, GI1787309, Length=518, Percent_Identity=41.6988416988417, Blast_Score=409, Evalue=1e-115,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004268 [H]

Pfam domain/function: PF03023 MVIN [H]

EC number: NA

Molecular weight: Translated: 57242; Mature: 57111

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ALWRSTFIVSAMTMLSRVLGLVRDMVLLNVFGAGKDFDTFVVAFRIPNFFRRLFAEGAF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCH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HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8200538; 11677609 [H]