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The map label for this gene is fabR [H]

Identifier: 50083341

GI number: 50083341

Start: 50905

End: 51540

Strand: Reverse

Name: fabR [H]

Synonym: ACIAD0047

Alternate gene names: 50083341

Gene position: 51540-50905 (Counterclockwise)

Preceding gene: 50083356

Following gene: 50083340

Centisome position: 1.43

GC content: 46.23

Gene sequence:

>636_bases
ATGTCGATACGGGATGAACGTAAACAGCAGAGCCGCCAGGCTTTACTTGATGCAGCATTGCAACTGAGTACAGGAGGTCG
TTCATTTAGCAGTATCAGTCTGCGCGAAGTTGCACGTGAAGTAGGATTGGTGCCCACTGCGTTCTATCGGCACTTTCAAG
ATATGGATGCATTGGGCCAAGAGCTGGTTGATCAGGTCGCACTTCATATCAAAAGCCTGATTCATCAGCTTGGACAAAGC
TATTTACAGCAAGTCAGCACGCATCCAGATAGCAGTATCGAGCTGTTTTTTCAGGCCATTAATCATAGTCCACTCGAATG
GCAATTTATGATTGCAGAGCGTTGGGGTGGATCTGCTGCGGTGCGTCAGGCGATTGCACGCGAAATTGAAGATTTGATTG
AAGATCTAGCCACCGATTTGCGCAAGCTACCGATGTTTGAACATATTCAGGATTCACAGGATCTGAAAGTTCTCTCTACC
ATTTTAATTAATCTTTCTTTTACTTGGGCCATGACTTGGCTCAGCCTTGCAAGCCAGTATCAGGATGCGGCACTATCGCA
ACACCAGCAACAGTTTGTTGAAAATGCCAATACTCAAATCCGTTTGATGTTTCGTGGCGTGGCAAACTGGGGATAA

Upstream 100 bases:

>100_bases
CAACAGGTGTTCACTCATTTTTTGATTTATTCTTTTTAACTTTTGTGAAAGGCAGTAAGTTTTTGGTAGACTCTTGACAG
GTTTTTAATAGGTCATGTGC

Downstream 100 bases:

>100_bases
GCTGGTTTTTTTGTTGAAGACCATGTGTTGTACATGATATAGAGTAAAGTGATATTAATTAAAGCAATAGACAATCTCGC
CAAAAGCAAATGGATGCTCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MSIRDERKQQSRQALLDAALQLSTGGRSFSSISLREVAREVGLVPTAFYRHFQDMDALGQELVDQVALHIKSLIHQLGQS
YLQQVSTHPDSSIELFFQAINHSPLEWQFMIAERWGGSAAVRQAIAREIEDLIEDLATDLRKLPMFEHIQDSQDLKVLST
ILINLSFTWAMTWLSLASQYQDAALSQHQQQFVENANTQIRLMFRGVANWG

Sequences:

>Translated_211_residues
MSIRDERKQQSRQALLDAALQLSTGGRSFSSISLREVAREVGLVPTAFYRHFQDMDALGQELVDQVALHIKSLIHQLGQS
YLQQVSTHPDSSIELFFQAINHSPLEWQFMIAERWGGSAAVRQAIAREIEDLIEDLATDLRKLPMFEHIQDSQDLKVLST
ILINLSFTWAMTWLSLASQYQDAALSQHQQQFVENANTQIRLMFRGVANWG
>Mature_210_residues
SIRDERKQQSRQALLDAALQLSTGGRSFSSISLREVAREVGLVPTAFYRHFQDMDALGQELVDQVALHIKSLIHQLGQSY
LQQVSTHPDSSIELFFQAINHSPLEWQFMIAERWGGSAAVRQAIAREIEDLIEDLATDLRKLPMFEHIQDSQDLKVLSTI
LINLSFTWAMTWLSLASQYQDAALSQHQQQFVENANTQIRLMFRGVANWG

Specific function: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, fabR directly influences the physical properties of the membrane bilayer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693209, Length=137, Percent_Identity=41.6058394160584, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24041; Mature: 23909

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRDERKQQSRQALLDAALQLSTGGRSFSSISLREVAREVGLVPTAFYRHFQDMDALGQ
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ELVDQVALHIKSLIHQLGQSYLQQVSTHPDSSIELFFQAINHSPLEWQFMIAERWGGSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEHHHHCCCHHH
VRQAIAREIEDLIEDLATDLRKLPMFEHIQDSQDLKVLSTILINLSFTWAMTWLSLASQY
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDAALSQHQQQFVENANTQIRLMFRGVANWG
HHHHHHHHHHHHHHCCCCEEEHHHHHHCCCC
>Mature Secondary Structure 
SIRDERKQQSRQALLDAALQLSTGGRSFSSISLREVAREVGLVPTAFYRHFQDMDALGQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ELVDQVALHIKSLIHQLGQSYLQQVSTHPDSSIELFFQAINHSPLEWQFMIAERWGGSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEHHHHCCCHHH
VRQAIAREIEDLIEDLATDLRKLPMFEHIQDSQDLKVLSTILINLSFTWAMTWLSLASQY
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDAALSQHQQQFVENANTQIRLMFRGVANWG
HHHHHHHHHHHHHHCCCCEEEHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA