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The map label for this gene is erpA

Identifier: 50083307

GI number: 50083307

Start: 12039

End: 12374

Strand: Direct

Name: erpA

Synonym: ACIAD0010

Alternate gene names: 50083307

Gene position: 12039-12374 (Clockwise)

Preceding gene: 50083306

Following gene: 50083309

Centisome position: 0.33

GC content: 41.96

Gene sequence:

>336_bases
ATGAATGCCCAAGCTCTTGTTATTACAGATAATGCTGCAAAAAAAGTGCGCCAACTCCGCGATAGCGAAGGCAATCAGGA
TTTGATGCTGCGTGTTTATGTGACAGGCGGTGGGTGTTCTGGCTTTTCTTATGGCTTTAATTTTGCTGATAGTCCCAACG
AAGATGATGCCGAGTTTGTAAATGGTGATGTCAAAATGTTAGTAGATTCACTGAGCTATCAGTATCTGGTAGGTTCGGTG
GTCGATTATATTGAAGGACTGGAAGGTTCTCGCTTTATAATCCAAAATCCAAATGCGACTACAACTTGCGGTTGTGGTTC
ATCATTTTCGATCTAA

Upstream 100 bases:

>100_bases
GAATAAAGTTTAAACTTGAAAGACAGTCCCCATATCGAATATGTTATACTGTTTCATGGTTTTAAGATGATATCTGAATC
TAGTCTGAGGAATACCTGTC

Downstream 100 bases:

>100_bases
AGATCGCTGGATTCAGAGCAATAAAAAAATCCCCGAAAGGGGATTTTTTTATTGGCCAGAATTAAACGCTGGTGATGGTT
CCCAAAATACGAAAACCTGC

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 111; Mature: 111

Protein sequence:

>111_residues
MNAQALVITDNAAKKVRQLRDSEGNQDLMLRVYVTGGGCSGFSYGFNFADSPNEDDAEFVNGDVKMLVDSLSYQYLVGSV
VDYIEGLEGSRFIIQNPNATTTCGCGSSFSI

Sequences:

>Translated_111_residues
MNAQALVITDNAAKKVRQLRDSEGNQDLMLRVYVTGGGCSGFSYGFNFADSPNEDDAEFVNGDVKMLVDSLSYQYLVGSV
VDYIEGLEGSRFIIQNPNATTTCGCGSSFSI
>Mature_111_residues
MNAQALVITDNAAKKVRQLRDSEGNQDLMLRVYVTGGGCSGFSYGFNFADSPNEDDAEFVNGDVKMLVDSLSYQYLVGSV
VDYIEGLEGSRFIIQNPNATTTCGCGSSFSI

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=105, Percent_Identity=40.9523809523809, Blast_Score=75, Evalue=2e-14,
Organism=Homo sapiens, GI52426768, Length=107, Percent_Identity=32.7102803738318, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1786351, Length=109, Percent_Identity=61.4678899082569, Blast_Score=132, Evalue=4e-33,
Organism=Escherichia coli, GI1788877, Length=109, Percent_Identity=38.5321100917431, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1787974, Length=109, Percent_Identity=33.0275229357798, Blast_Score=62, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71998452, Length=113, Percent_Identity=37.1681415929204, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25146411, Length=107, Percent_Identity=32.7102803738318, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193209025, Length=107, Percent_Identity=32.7102803738318, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=31.1320754716981, Blast_Score=69, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=46.9879518072289, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24642263, Length=107, Percent_Identity=34.5794392523364, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_ACIAD (Q6FG12)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_044817.1
- HSSP:   O67709
- ProteinModelPortal:   Q6FG12
- SMR:   Q6FG12
- STRING:   Q6FG12
- GeneID:   2880987
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0010
- NMPDR:   fig|62977.3.peg.1077
- eggNOG:   COG0316
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- PhylomeDB:   Q6FG12
- ProtClustDB:   PRK13623
- BioCyc:   ASP62977:ACIAD0010-MONOMER
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 11966; Mature: 11966

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAQALVITDNAAKKVRQLRDSEGNQDLMLRVYVTGGGCSGFSYGFNFADSPNEDDAEFV
CCCCEEEEECHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHH
NGDVKMLVDSLSYQYLVGSVVDYIEGLEGSRFIIQNPNATTTCGCGSSFSI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCCCCCC
>Mature Secondary Structure
MNAQALVITDNAAKKVRQLRDSEGNQDLMLRVYVTGGGCSGFSYGFNFADSPNEDDAEFV
CCCCEEEEECHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHH
NGDVKMLVDSLSYQYLVGSVVDYIEGLEGSRFIIQNPNATTTCGCGSSFSI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA