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The map label for this gene is galE

Identifier: 49480462

GI number: 49480462

Start: 5198047

End: 5199063

Strand: Reverse

Name: galE

Synonym: BT9727_5131

Alternate gene names: 49480462

Gene position: 5199063-5198047 (Counterclockwise)

Preceding gene: 49481225

Following gene: 49481230

Centisome position: 99.26

GC content: 35.2

Gene sequence:

>1017_bases
ATGGCGATACTTATAACGGGTGGAGCAGGGTATATTGGTAGTCATACATGTGTAGAATTATTAAATAATAATTATAAAAT
TATAGTCGTAGATAATCTTTCAAATAGTTCAATTGAATCTTTAAATCGAGTAAAAGAAATAACAGGAAAACAATTTGAAT
TTTATAAAGAAAATGTTTTAAATCGTGAAAAAATGAATGAGATCTTTTTGGAAAATAACATTGAAGCGGTTATACATTTT
GCGGGGTTTAAAGCAGTGGGGGAATCTACCACAACACCACTTGCATATTATTATAACAATATAATAAGTGCAATTGTACT
ATGTGATGTGATGCAAAAACACAATGTTAAAAATTTTATTTTTAGTTCATCTGCAACTGTATATGGAATTCCAAAAACAT
CACCAATTACAGAAGAATTTCCGCTGAGTGTGACAAATCCGTATGGACAAACAAAATTAATGATTGAGCAAATTATGCGT
GATGTAGCAAAGGCTGATGATGAGTGGAGCATTGCATTACTTCGTTATTTTAATCCATTTGGAGCTCATCAAAGTGGCCG
TATCGGAGAAGATCCAAATGGGATTCCGAACAATTTAATGCCATATGTAACGCAAGTAGCGGTAGGTAAGTTAAAGGAGC
TAAATATATTCGGAAACGATTATCCAACGAAAGATGGGACGGGTGTCCGTGATTATATTCACGTTGTTGACCTTGCGAAG
GGGCATGTAAAGGCACTTGAGAAAGTACTTAAGACGAAAGGAATCGAGGCATATAATCTTGGCACAGGTAAAGGGTATAG
TGTATTGGAGATGGTAAAGGCTTTTGAGAAGGTTTCGGGTAAAAAAATACCTTATAAAGTGATAGGGCGTCGTCCTGGTG
ATGTAGCAATCTGTTTTGCGGATGTATCTAAAGCGAAACGAGAATTAGGATGGGAAGCGGAATATGGGTTAGAAGAGATG
TGTGTAGATTCTTGGAGATGGCAAGTAAATAATAAAAATGGCTATCAAATGATTTAG

Upstream 100 bases:

>100_bases
TGAAAATAATTTTTAGAATTATCAGTCTTTTTCGTGGTAAGATATATGTGCATTGAGATTATAAAATTTTATAATTAATA
ATTAGTGGGGGACTATAGAT

Downstream 100 bases:

>100_bases
GGTACCTAGTAAAGCATGCTCTTATTATGTTGCTTGAGGTCAGTAATATGTTCATTTTAGGAAAGAGAATGTAATAAAAT
ATTACTGACCATAGCGTTTG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MAILITGGAGYIGSHTCVELLNNNYKIIVVDNLSNSSIESLNRVKEITGKQFEFYKENVLNREKMNEIFLENNIEAVIHF
AGFKAVGESTTTPLAYYYNNIISAIVLCDVMQKHNVKNFIFSSSATVYGIPKTSPITEEFPLSVTNPYGQTKLMIEQIMR
DVAKADDEWSIALLRYFNPFGAHQSGRIGEDPNGIPNNLMPYVTQVAVGKLKELNIFGNDYPTKDGTGVRDYIHVVDLAK
GHVKALEKVLKTKGIEAYNLGTGKGYSVLEMVKAFEKVSGKKIPYKVIGRRPGDVAICFADVSKAKRELGWEAEYGLEEM
CVDSWRWQVNNKNGYQMI

Sequences:

>Translated_338_residues
MAILITGGAGYIGSHTCVELLNNNYKIIVVDNLSNSSIESLNRVKEITGKQFEFYKENVLNREKMNEIFLENNIEAVIHF
AGFKAVGESTTTPLAYYYNNIISAIVLCDVMQKHNVKNFIFSSSATVYGIPKTSPITEEFPLSVTNPYGQTKLMIEQIMR
DVAKADDEWSIALLRYFNPFGAHQSGRIGEDPNGIPNNLMPYVTQVAVGKLKELNIFGNDYPTKDGTGVRDYIHVVDLAK
GHVKALEKVLKTKGIEAYNLGTGKGYSVLEMVKAFEKVSGKKIPYKVIGRRPGDVAICFADVSKAKRELGWEAEYGLEEM
CVDSWRWQVNNKNGYQMI
>Mature_337_residues
AILITGGAGYIGSHTCVELLNNNYKIIVVDNLSNSSIESLNRVKEITGKQFEFYKENVLNREKMNEIFLENNIEAVIHFA
GFKAVGESTTTPLAYYYNNIISAIVLCDVMQKHNVKNFIFSSSATVYGIPKTSPITEEFPLSVTNPYGQTKLMIEQIMRD
VAKADDEWSIALLRYFNPFGAHQSGRIGEDPNGIPNNLMPYVTQVAVGKLKELNIFGNDYPTKDGTGVRDYIHVVDLAKG
HVKALEKVLKTKGIEAYNLGTGKGYSVLEMVKAFEKVSGKKIPYKVIGRRPGDVAICFADVSKAKRELGWEAEYGLEEMC
VDSWRWQVNNKNGYQMI

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=57.6470588235294, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=57.6470588235294, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=57.6470588235294, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI7657641, Length=274, Percent_Identity=26.6423357664234, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI42516563, Length=325, Percent_Identity=22.7692307692308, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=55.0595238095238, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI48994969, Length=362, Percent_Identity=25.414364640884, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1788353, Length=364, Percent_Identity=27.1978021978022, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=55.3623188405797, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=55.043227665706, Blast_Score=393, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17568069, Length=336, Percent_Identity=26.7857142857143, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=53.7790697674419, Blast_Score=377, Evalue=1e-105,
Organism=Drosophila melanogaster, GI19923002, Length=342, Percent_Identity=57.3099415204678, Blast_Score=419, Evalue=1e-117,
Organism=Drosophila melanogaster, GI21356223, Length=349, Percent_Identity=22.6361031518625, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37820; Mature: 37689

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILITGGAGYIGSHTCVELLNNNYKIIVVDNLSNSSIESLNRVKEITGKQFEFYKENVL
CEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHC
NREKMNEIFLENNIEAVIHFAGFKAVGESTTTPLAYYYNNIISAIVLCDVMQKHNVKNFI
CHHHHHHHHHCCCCEEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHE
FSSSATVYGIPKTSPITEEFPLSVTNPYGQTKLMIEQIMRDVAKADDEWSIALLRYFNPF
EECCCEEEECCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHCCC
GAHQSGRIGEDPNGIPNNLMPYVTQVAVGKLKELNIFGNDYPTKDGTGVRDYIHVVDLAK
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHEEEEECCCCCCCCCCCHHHHHHHHHHHH
GHVKALEKVLKTKGIEAYNLGTGKGYSVLEMVKAFEKVSGKKIPYKVIGRRPGDVAICFA
HHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCHHEECCCCCCEEEEEH
DVSKAKRELGWEAEYGLEEMCVDSWRWQVNNKNGYQMI
HHHHHHHHCCCCHHCCHHHHHHHHHEEEECCCCCCCCC
>Mature Secondary Structure 
AILITGGAGYIGSHTCVELLNNNYKIIVVDNLSNSSIESLNRVKEITGKQFEFYKENVL
EEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHC
NREKMNEIFLENNIEAVIHFAGFKAVGESTTTPLAYYYNNIISAIVLCDVMQKHNVKNFI
CHHHHHHHHHCCCCEEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHE
FSSSATVYGIPKTSPITEEFPLSVTNPYGQTKLMIEQIMRDVAKADDEWSIALLRYFNPF
EECCCEEEECCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHCCC
GAHQSGRIGEDPNGIPNNLMPYVTQVAVGKLKELNIFGNDYPTKDGTGVRDYIHVVDLAK
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCHHEEEEECCCCCCCCCCCHHHHHHHHHHHH
GHVKALEKVLKTKGIEAYNLGTGKGYSVLEMVKAFEKVSGKKIPYKVIGRRPGDVAICFA
HHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCHHEECCCCCCEEEEEH
DVSKAKRELGWEAEYGLEEMCVDSWRWQVNNKNGYQMI
HHHHHHHHCCCCHHCCHHHHHHHHHEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]