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The map label for this gene is metA

Identifier: 49480444

GI number: 49480444

Start: 5146320

End: 5147225

Strand: Reverse

Name: metA

Synonym: BT9727_5086

Alternate gene names: 49480444

Gene position: 5147225-5146320 (Counterclockwise)

Preceding gene: 49480445

Following gene: 49481300

Centisome position: 98.27

GC content: 36.87

Gene sequence:

>906_bases
ATGCCGATCATAATTGATAAAGATTTACCAGCTCGCAAAGTATTGCAGGAGGAAAATATTTTTGTAATGACAAAAGAGCG
AGCAGAAACACAAGATATCCGGGCATTGAAAATTGCTATATTAAATTTAATGCCTACAAAGCAAGAAACAGAAGCGCAAT
TACTTCGTTTAATTGGAAATACACCGTTGCAATTAGATGTTCATTTACTTCATATGGAATCACATCTGTCCCGTAATGTA
GCACAGGAGCATTTAACAAGTTTTTATAAAACATTCCGTGATATTGAGAATGAGAAATTTGATGGACTCATTATTACAGG
AGCACCAGTTGAAACCCTTTCTTTTGAAGAGGTAGATTATTGGGAAGAGCTTAAACGTATTATGGAGTATTCAAAAACAA
ATGTAACATCTACGCTTCATATTTGCTGGGGGGCACAGGCTGGTTTGTATCATCATTATGGCGTTCAAAAGTATCCTCTT
AAGGAAAAAATGTTTGGTGTATTTGAACATGAAGTTCGTGAGCAACATGTGAAATTGTTACAAGGGTTTGATGAGTTATT
TTTTGCCCCGCATTCTCGTCATACGGAAGTACGAGAGAGTGACATTAGAGGAGTGAAAGAATTAACATTGTTAGCAAACT
CTGAAGAGGCAGGTGTTCACCTTGTTATTGGACCAGAAGGAAGGCAAGTGTTTGCGCTTGGGCATAGTGAATATAGTTGT
GATACGTTAAAACAAGAATACGAACGGGACCGCCAAAAAGGGTTAAATATTGATGTGCCGAAAAACTATTTTAAACATAA
TAATCCAAATGAGAAGCCGCTTGTACGGTGGAGGAGCCATGGGAATCTATTATTCTCTAATTGGCTGAATTATTACGTGT
ATCAAGAAACCCCTTATGTATTATAA

Upstream 100 bases:

>100_bases
GCTGGCGTCACATCAGATTTAATTCGTTTATCAGTTGGCATAGAAGATGTTTTTGATATTATTGCAGATTTAGAAGCAGC
GCTAGTCGGAGGCAAACAAC

Downstream 100 bases:

>100_bases
AAAAAGATTGTGTCACACGTGGCAACGTTTTCTTTGTAAAGGTTAATCTATATTATTCCGAATGTTCGAAAAACATTGTT
TTTCAGATTTTTTACTCATA

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MPIIIDKDLPARKVLQEENIFVMTKERAETQDIRALKIAILNLMPTKQETEAQLLRLIGNTPLQLDVHLLHMESHLSRNV
AQEHLTSFYKTFRDIENEKFDGLIITGAPVETLSFEEVDYWEELKRIMEYSKTNVTSTLHICWGAQAGLYHHYGVQKYPL
KEKMFGVFEHEVREQHVKLLQGFDELFFAPHSRHTEVRESDIRGVKELTLLANSEEAGVHLVIGPEGRQVFALGHSEYSC
DTLKQEYERDRQKGLNIDVPKNYFKHNNPNEKPLVRWRSHGNLLFSNWLNYYVYQETPYVL

Sequences:

>Translated_301_residues
MPIIIDKDLPARKVLQEENIFVMTKERAETQDIRALKIAILNLMPTKQETEAQLLRLIGNTPLQLDVHLLHMESHLSRNV
AQEHLTSFYKTFRDIENEKFDGLIITGAPVETLSFEEVDYWEELKRIMEYSKTNVTSTLHICWGAQAGLYHHYGVQKYPL
KEKMFGVFEHEVREQHVKLLQGFDELFFAPHSRHTEVRESDIRGVKELTLLANSEEAGVHLVIGPEGRQVFALGHSEYSC
DTLKQEYERDRQKGLNIDVPKNYFKHNNPNEKPLVRWRSHGNLLFSNWLNYYVYQETPYVL
>Mature_300_residues
PIIIDKDLPARKVLQEENIFVMTKERAETQDIRALKIAILNLMPTKQETEAQLLRLIGNTPLQLDVHLLHMESHLSRNVA
QEHLTSFYKTFRDIENEKFDGLIITGAPVETLSFEEVDYWEELKRIMEYSKTNVTSTLHICWGAQAGLYHHYGVQKYPLK
EKMFGVFEHEVREQHVKLLQGFDELFFAPHSRHTEVRESDIRGVKELTLLANSEEAGVHLVIGPEGRQVFALGHSEYSCD
TLKQEYERDRQKGLNIDVPKNYFKHNNPNEKPLVRWRSHGNLLFSNWLNYYVYQETPYVL

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=301, Percent_Identity=51.4950166112957, Blast_Score=329, Evalue=1e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 35250; Mature: 35118

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIIIDKDLPARKVLQEENIFVMTKERAETQDIRALKIAILNLMPTKQETEAQLLRLIGN
CCEEECCCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
TPLQLDVHLLHMESHLSRNVAQEHLTSFYKTFRDIENEKFDGLIITGAPVETLSFEEVDY
CCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHH
WEELKRIMEYSKTNVTSTLHICWGAQAGLYHHYGVQKYPLKEKMFGVFEHEVREQHVKLL
HHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QGFDELFFAPHSRHTEVRESDIRGVKELTLLANSEEAGVHLVIGPEGRQVFALGHSEYSC
HHHHHHHCCCCCCCCHHHHHHHCCHHHHEEEECCCCCCEEEEECCCCCEEEEECCCCCCH
DTLKQEYERDRQKGLNIDVPKNYFKHNNPNEKPLVRWRSHGNLLFSNWLNYYVYQETPYV
HHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCEEEECCCCCEEEECHHCEEEEECCCCC
L
C
>Mature Secondary Structure 
PIIIDKDLPARKVLQEENIFVMTKERAETQDIRALKIAILNLMPTKQETEAQLLRLIGN
CEEECCCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
TPLQLDVHLLHMESHLSRNVAQEHLTSFYKTFRDIENEKFDGLIITGAPVETLSFEEVDY
CCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHH
WEELKRIMEYSKTNVTSTLHICWGAQAGLYHHYGVQKYPLKEKMFGVFEHEVREQHVKLL
HHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QGFDELFFAPHSRHTEVRESDIRGVKELTLLANSEEAGVHLVIGPEGRQVFALGHSEYSC
HHHHHHHCCCCCCCCHHHHHHHCCHHHHEEEECCCCCCEEEEECCCCCEEEEECCCCCCH
DTLKQEYERDRQKGLNIDVPKNYFKHNNPNEKPLVRWRSHGNLLFSNWLNYYVYQETPYV
HHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCEEEECCCCCEEEECHHCEEEEECCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA