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The map label for this gene is yvfT [H]

Identifier: 49480426

GI number: 49480426

Start: 5089288

End: 5090418

Strand: Reverse

Name: yvfT [H]

Synonym: BT9727_5035

Alternate gene names: 49480426

Gene position: 5090418-5089288 (Counterclockwise)

Preceding gene: 49480803

Following gene: 49480425

Centisome position: 97.19

GC content: 35.01

Gene sequence:

>1131_bases
ATGTTAGAGAAAAAGAGAATTGAGATTTTTCCGAAACATATGGGTTTCTTCCCGTATATGTGGTTCGTTTATTTATTATT
TCCAATTTACCATTTAGTGCAGGCGTCAGGGTGGAAGCTTATAATTGGGAGCGGTATGTTGATAATTTTTATTATCACAT
ACCGTCAGCTTTATTTTGTGCAGAGGACGTTTATTTTTTGGGCGTGTATTCAAATGATACTCATCTTTTTATTTTCCATA
TTTTATAACGCTTTTATGATATTTTTTGGTTTTTTCACAGCAAGTGCGATGGGATTTGCACCAAGTAAAAAAGTATTTCG
AGTATTATTAGGACTGTTGATTACAATGCTTGGAGCATTTATATTTGTATATTTTAATCGACTATCTACTACAAGTTTAG
TAAATATCATTCCAATGTTTATTTTAATGCTTCTTACACCATTTGGTATGCGCAACTTTAATCAGAAAAAGATGTTAAGA
AATCAATTAAATGAAGCGAATGAGCAAATTAAAGACTTAGTAAAACGTGAAGAACGGCAGCGGATTGCAAGAGATCTTCA
TGATACGTTAGGGCATACATTATCACTCATTACTTTAAAAAGTCAGCTCGTGGAGAAGTTAATTGTAAAAAATCCGGAGC
GTGCAAGTACGGAAGCGAAGGAAATTACACAAACATCTCGCACTGCTTTAAAGCAGCTAAGGGAATTAATTTCTGATATG
CGTATGATTACAGTAGAAGAAGAGCTTGAGCAAATAAAAGCAATCTTACAAGCTGCTAATATTGGATTAGAGATTAAACA
AGAAACGAGTGCGAGTTCTTTATCACCAATTGAACAAAATATTTTAGGAATGTGTTTACGTGAGGCAGTGACGAATGTTG
TAAAGCATAGTAAGGCGACGCGTTGCACAGTTTCTGTACTAGAATCACAAGGCGAATTAATTTTGACAGTAGAAGATAAT
GGAATTGGCTTGGCAGATCAAAACCATGATGGAAATGGCATTCGTGGCATGAAAGAGCGAATCGCTCTTATTGATGGATT
CGTTGAACTAGGTACGATTAATCCAGGGACATTATTAACAGTAAAAGTTCCAGTTGTTATTCGAACAGGAAAAGATGAGG
TGAAGGCATGA

Upstream 100 bases:

>100_bases
AAAATCAATTGGATGGGAAAATATCGCGGTACTAGGAGGTTATTTCCTTATATTTGTTGTAATATCAATATATATAAGAA
AAAGACAGGAAGCGGTATAA

Downstream 100 bases:

>100_bases
TTCGAATTATTATTGCAGAAGATCAGCGAATGCTTCGTGGTGCATTAGGGGCCCTGCTTGATCTAGAAGATGATATTGAA
GTAATTGGGCAAGCTGCGAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MLEKKRIEIFPKHMGFFPYMWFVYLLFPIYHLVQASGWKLIIGSGMLIIFIITYRQLYFVQRTFIFWACIQMILIFLFSI
FYNAFMIFFGFFTASAMGFAPSKKVFRVLLGLLITMLGAFIFVYFNRLSTTSLVNIIPMFILMLLTPFGMRNFNQKKMLR
NQLNEANEQIKDLVKREERQRIARDLHDTLGHTLSLITLKSQLVEKLIVKNPERASTEAKEITQTSRTALKQLRELISDM
RMITVEEELEQIKAILQAANIGLEIKQETSASSLSPIEQNILGMCLREAVTNVVKHSKATRCTVSVLESQGELILTVEDN
GIGLADQNHDGNGIRGMKERIALIDGFVELGTINPGTLLTVKVPVVIRTGKDEVKA

Sequences:

>Translated_376_residues
MLEKKRIEIFPKHMGFFPYMWFVYLLFPIYHLVQASGWKLIIGSGMLIIFIITYRQLYFVQRTFIFWACIQMILIFLFSI
FYNAFMIFFGFFTASAMGFAPSKKVFRVLLGLLITMLGAFIFVYFNRLSTTSLVNIIPMFILMLLTPFGMRNFNQKKMLR
NQLNEANEQIKDLVKREERQRIARDLHDTLGHTLSLITLKSQLVEKLIVKNPERASTEAKEITQTSRTALKQLRELISDM
RMITVEEELEQIKAILQAANIGLEIKQETSASSLSPIEQNILGMCLREAVTNVVKHSKATRCTVSVLESQGELILTVEDN
GIGLADQNHDGNGIRGMKERIALIDGFVELGTINPGTLLTVKVPVVIRTGKDEVKA
>Mature_376_residues
MLEKKRIEIFPKHMGFFPYMWFVYLLFPIYHLVQASGWKLIIGSGMLIIFIITYRQLYFVQRTFIFWACIQMILIFLFSI
FYNAFMIFFGFFTASAMGFAPSKKVFRVLLGLLITMLGAFIFVYFNRLSTTSLVNIIPMFILMLLTPFGMRNFNQKKMLR
NQLNEANEQIKDLVKREERQRIARDLHDTLGHTLSLITLKSQLVEKLIVKNPERASTEAKEITQTSRTALKQLRELISDM
RMITVEEELEQIKAILQAANIGLEIKQETSASSLSPIEQNILGMCLREAVTNVVKHSKATRCTVSVLESQGELILTVEDN
GIGLADQNHDGNGIRGMKERIALIDGFVELGTINPGTLLTVKVPVVIRTGKDEVKA

Specific function: Member of the two-component regulatory system yvfT/yvfU. Probably activates yvfU by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788812, Length=218, Percent_Identity=27.5229357798165, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082311, Length=227, Percent_Identity=27.7533039647577, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787474, Length=193, Percent_Identity=30.0518134715026, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011712 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42929; Mature: 42929

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50109 HIS_KIN ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKKRIEIFPKHMGFFPYMWFVYLLFPIYHLVQASGWKLIIGSGMLIIFIITYRQLYFV
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHH
QRTFIFWACIQMILIFLFSIFYNAFMIFFGFFTASAMGFAPSKKVFRVLLGLLITMLGAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IFVYFNRLSTTSLVNIIPMFILMLLTPFGMRNFNQKKMLRNQLNEANEQIKDLVKREERQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RIARDLHDTLGHTLSLITLKSQLVEKLIVKNPERASTEAKEITQTSRTALKQLRELISDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RMITVEEELEQIKAILQAANIGLEIKQETSASSLSPIEQNILGMCLREAVTNVVKHSKAT
HHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
RCTVSVLESQGELILTVEDNGIGLADQNHDGNGIRGMKERIALIDGFVELGTINPGTLLT
HHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
VKVPVVIRTGKDEVKA
EEEEEEEECCCHHCCC
>Mature Secondary Structure
MLEKKRIEIFPKHMGFFPYMWFVYLLFPIYHLVQASGWKLIIGSGMLIIFIITYRQLYFV
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHH
QRTFIFWACIQMILIFLFSIFYNAFMIFFGFFTASAMGFAPSKKVFRVLLGLLITMLGAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
IFVYFNRLSTTSLVNIIPMFILMLLTPFGMRNFNQKKMLRNQLNEANEQIKDLVKREERQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RIARDLHDTLGHTLSLITLKSQLVEKLIVKNPERASTEAKEITQTSRTALKQLRELISDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RMITVEEELEQIKAILQAANIGLEIKQETSASSLSPIEQNILGMCLREAVTNVVKHSKAT
HHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
RCTVSVLESQGELILTVEDNGIGLADQNHDGNGIRGMKERIALIDGFVELGTINPGTLLT
HHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
VKVPVVIRTGKDEVKA
EEEEEEEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]