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The map label for this gene is yisV [H]

Identifier: 49479178

GI number: 49479178

Start: 3581445

End: 3582878

Strand: Reverse

Name: yisV [H]

Synonym: BT9727_3499

Alternate gene names: 49479178

Gene position: 3582878-3581445 (Counterclockwise)

Preceding gene: 49479425

Following gene: 49478363

Centisome position: 68.41

GC content: 37.03

Gene sequence:

>1434_bases
ATGGAATGGAAACCAAATCGTGCAGATAAGACACCTGTATATAAACAAATTGCTGATTATATTGAAAGAGGCATTTCTTC
AGGTGAATTTCCTTCTGATAGTAAGTTACCTTCTGAGCGTATATTGGCAAAGGAATTACAGGTGAACCGGAGTACAATAG
TAGCTGCGTATGAAGAATTAAAATCACTTGGAGTAGTAGAACGGCAAAAAGGGAGCGGAACACGGGTGAATACAGACATA
TGGGGTGTGTCACATAAACGAATACCGAACTGGGGTAGGTACGTTGAGGATGGATCGTTCTTACCTAATGTACCACTCGT
TCAACAAATTCGAACGGAAACACAAAAAGATGACTTAATTAATTTAGCGAGTGGTGAATTATCACCAGAATTAATTCCGA
GTGATAGATTCCGAACGATTTTGTCGGAGAAAACATTTATGGAAAACCTCGGTTATGACCATCCACTTGGAAATGAAATG
TTGAGAAAAACAATTGCAGCACATGTTCAGCAATATAAACAAATTGAAGCAGATTCGAACTCTATTCTTATTACATCTGG
AGCACAACAAGCTCTTAATCTTATCGTTCAGTGCTTATTAAAACCTGGTGATGCGATTGCAATTGAGGACCCTTCGTATT
GTTTCTCATTGCCGATGTTTAAATCTGCTGGTTTAAAAATATTTCATTTACCTGTTGATCAGCATGGAATGAATCCAGAT
GACCTAATTGATTTGCATAAAAAGCATCGTATTCGCATGGTATTTTTAAATCCAGATTATCAAAATCCAACGGGAACTGT
GCTGTCATTAGCAAGACGTAAAAAGATTTTAGAACTGTCTTCTGAATTTGGTATACCGATTGTAGAAGATGATCCGTATA
GTTTAACGTCCTTTAATGGAGAAGTGAATCCAACATTAAAATCAATGGATCAAAACGGGAATGTTCTTTATGTAAGTTCA
TTATCAAAAATTGTTGCATCGGGATTACGTATTGGCTGGGTAATTGGTCCTACGCGTGTAATAGAACGTTTAGCGGATGC
GAAGCAGCAAGTTGATTTTGGGCATAGTGTATTTACGCAGTGGGTGGCAAATCAATTTTTAGAATCAGACGATTTTCATG
CGCATATTACAATGCTTCGTAGACAATTGAAAGAAAGAAGAGATGTATTAATTAGAAAGCTTGAAGAAATATTAGGAGAC
CAGGTTGAATTTTTTGTTCCAGAGGGTGGAATACATTTATGGTGCAAAGTGCAAGGAACGTTTGATGAGTATCATTTATT
AGGTGAATCTATACGAAATGGTGTAGCGTTTGTCCCGGGTAGTGTTTTAGGTACTAAAAGTGAATATATTCGTTTTACTT
TTGGGAGAGTAAATGCCGAACAAATTCAGCTGGGAATGACGAGGTTTGCTGAAACGTTAAATGAGATTTCATAA

Upstream 100 bases:

>100_bases
CCATTTTAGGATGAGAAAATGTGACTAATTAATACTATTTTTACGGTAAATACTGTTAGTAATAAATTGAGGATAGTTAG
CTTTGAAAGGAGGCAACTAT

Downstream 100 bases:

>100_bases
TAGTGATACGTAATATTGAAATGAGGGAAAGAAATGAAGTACGTGATGCTTTTACTTCAAGTAGGCGTGCTGTATGTATT
TAGTTTAGTTGGTACGTGGA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MEWKPNRADKTPVYKQIADYIERGISSGEFPSDSKLPSERILAKELQVNRSTIVAAYEELKSLGVVERQKGSGTRVNTDI
WGVSHKRIPNWGRYVEDGSFLPNVPLVQQIRTETQKDDLINLASGELSPELIPSDRFRTILSEKTFMENLGYDHPLGNEM
LRKTIAAHVQQYKQIEADSNSILITSGAQQALNLIVQCLLKPGDAIAIEDPSYCFSLPMFKSAGLKIFHLPVDQHGMNPD
DLIDLHKKHRIRMVFLNPDYQNPTGTVLSLARRKKILELSSEFGIPIVEDDPYSLTSFNGEVNPTLKSMDQNGNVLYVSS
LSKIVASGLRIGWVIGPTRVIERLADAKQQVDFGHSVFTQWVANQFLESDDFHAHITMLRRQLKERRDVLIRKLEEILGD
QVEFFVPEGGIHLWCKVQGTFDEYHLLGESIRNGVAFVPGSVLGTKSEYIRFTFGRVNAEQIQLGMTRFAETLNEIS

Sequences:

>Translated_477_residues
MEWKPNRADKTPVYKQIADYIERGISSGEFPSDSKLPSERILAKELQVNRSTIVAAYEELKSLGVVERQKGSGTRVNTDI
WGVSHKRIPNWGRYVEDGSFLPNVPLVQQIRTETQKDDLINLASGELSPELIPSDRFRTILSEKTFMENLGYDHPLGNEM
LRKTIAAHVQQYKQIEADSNSILITSGAQQALNLIVQCLLKPGDAIAIEDPSYCFSLPMFKSAGLKIFHLPVDQHGMNPD
DLIDLHKKHRIRMVFLNPDYQNPTGTVLSLARRKKILELSSEFGIPIVEDDPYSLTSFNGEVNPTLKSMDQNGNVLYVSS
LSKIVASGLRIGWVIGPTRVIERLADAKQQVDFGHSVFTQWVANQFLESDDFHAHITMLRRQLKERRDVLIRKLEEILGD
QVEFFVPEGGIHLWCKVQGTFDEYHLLGESIRNGVAFVPGSVLGTKSEYIRFTFGRVNAEQIQLGMTRFAETLNEIS
>Mature_477_residues
MEWKPNRADKTPVYKQIADYIERGISSGEFPSDSKLPSERILAKELQVNRSTIVAAYEELKSLGVVERQKGSGTRVNTDI
WGVSHKRIPNWGRYVEDGSFLPNVPLVQQIRTETQKDDLINLASGELSPELIPSDRFRTILSEKTFMENLGYDHPLGNEM
LRKTIAAHVQQYKQIEADSNSILITSGAQQALNLIVQCLLKPGDAIAIEDPSYCFSLPMFKSAGLKIFHLPVDQHGMNPD
DLIDLHKKHRIRMVFLNPDYQNPTGTVLSLARRKKILELSSEFGIPIVEDDPYSLTSFNGEVNPTLKSMDQNGNVLYVSS
LSKIVASGLRIGWVIGPTRVIERLADAKQQVDFGHSVFTQWVANQFLESDDFHAHITMLRRQLKERRDVLIRKLEEILGD
QVEFFVPEGGIHLWCKVQGTFDEYHLLGESIRNGVAFVPGSVLGTKSEYIRFTFGRVNAEQIQLGMTRFAETLNEIS

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=432, Percent_Identity=28.2407407407407, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI33469970, Length=432, Percent_Identity=28.2407407407407, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI56713256, Length=318, Percent_Identity=23.8993710691824, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI56713254, Length=318, Percent_Identity=23.8993710691824, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790797, Length=440, Percent_Identity=26.5909090909091, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787710, Length=465, Percent_Identity=25.8064516129032, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788722, Length=276, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786816, Length=359, Percent_Identity=22.8412256267409, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321236, Length=392, Percent_Identity=23.2142857142857, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21356535, Length=391, Percent_Identity=21.9948849104859, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI18859735, Length=343, Percent_Identity=21.865889212828, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53882; Mature: 53882

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWKPNRADKTPVYKQIADYIERGISSGEFPSDSKLPSERILAKELQVNRSTIVAAYEEL
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
KSLGVVERQKGSGTRVNTDIWGVSHKRIPNWGRYVEDGSFLPNVPLVQQIRTETQKDDLI
HHCCCEEECCCCCCEECCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NLASGELSPELIPSDRFRTILSEKTFMENLGYDHPLGNEMLRKTIAAHVQQYKQIEADSN
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
SILITSGAQQALNLIVQCLLKPGDAIAIEDPSYCFSLPMFKSAGLKIFHLPVDQHGMNPD
EEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCHHHCCCEEEEECCHHCCCCHH
DLIDLHKKHRIRMVFLNPDYQNPTGTVLSLARRKKILELSSEFGIPIVEDDPYSLTSFNG
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCC
EVNPTLKSMDQNGNVLYVSSLSKIVASGLRIGWVIGPTRVIERLADAKQQVDFGHSVFTQ
CCCCHHHHCCCCCCEEEEHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCHHHHHHH
WVANQFLESDDFHAHITMLRRQLKERRDVLIRKLEEILGDQVEFFVPEGGIHLWCKVQGT
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEECC
FDEYHLLGESIRNGVAFVPGSVLGTKSEYIRFTFGRVNAEQIQLGMTRFAETLNEIS
HHHHHHHHHHHHCCEEECCCCHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEWKPNRADKTPVYKQIADYIERGISSGEFPSDSKLPSERILAKELQVNRSTIVAAYEEL
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
KSLGVVERQKGSGTRVNTDIWGVSHKRIPNWGRYVEDGSFLPNVPLVQQIRTETQKDDLI
HHCCCEEECCCCCCEECCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NLASGELSPELIPSDRFRTILSEKTFMENLGYDHPLGNEMLRKTIAAHVQQYKQIEADSN
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
SILITSGAQQALNLIVQCLLKPGDAIAIEDPSYCFSLPMFKSAGLKIFHLPVDQHGMNPD
EEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCHHHCCCEEEEECCHHCCCCHH
DLIDLHKKHRIRMVFLNPDYQNPTGTVLSLARRKKILELSSEFGIPIVEDDPYSLTSFNG
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECCC
EVNPTLKSMDQNGNVLYVSSLSKIVASGLRIGWVIGPTRVIERLADAKQQVDFGHSVFTQ
CCCCHHHHCCCCCCEEEEHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCHHHHHHH
WVANQFLESDDFHAHITMLRRQLKERRDVLIRKLEEILGDQVEFFVPEGGIHLWCKVQGT
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEEECC
FDEYHLLGESIRNGVAFVPGSVLGTKSEYIRFTFGRVNAEQIQLGMTRFAETLNEIS
HHHHHHHHHHHHCCEEECCCCHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]