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The map label for this gene is cidA2 [H]

Identifier: 49478363

GI number: 49478363

Start: 3581157

End: 3581411

Strand: Reverse

Name: cidA2 [H]

Synonym: BT9727_3498

Alternate gene names: 49478363

Gene position: 3581411-3581157 (Counterclockwise)

Preceding gene: 49479178

Following gene: 49479424

Centisome position: 68.38

GC content: 34.9

Gene sequence:

>255_bases
ATGAAGTACGTGATGCTTTTACTTCAAGTAGGCGTGCTGTATGTATTTAGTTTAGTTGGTACGTGGATTCAAGGAGTATT
CCATTTATCAATGCCAGGAAGTTTAATAGGAATGTTAATGCTGTTTCTGCTCCTTTCCACTCGTATTTTACCATTAAAGT
GGTTTGAAGAAGCGACAATCGGTTCGGTGACTATGATTGTAACAGGAATACTCATCAGTATATTTATACCATATGGAACG
AAATTTATATTTTAA

Upstream 100 bases:

>100_bases
AGTAAATGCCGAACAAATTCAGCTGGGAATGACGAGGTTTGCTGAAACGTTAAATGAGATTTCATAATAGTGATACGTAA
TATTGAAATGAGGGAAAGAA

Downstream 100 bases:

>100_bases
ATTGTAATGGAGATGATGAAAGTGACAACATGGTTTATAGTTACATTATTTATTTTTGGTGCCCTTAAAGTACTCGTTTC
TAGTATGCCAACTTCAGTTG

Product: murein hydrolase exporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 84; Mature: 84

Protein sequence:

>84_residues
MKYVMLLLQVGVLYVFSLVGTWIQGVFHLSMPGSLIGMLMLFLLLSTRILPLKWFEEATIGSVTMIVTGILISIFIPYGT
KFIF

Sequences:

>Translated_84_residues
MKYVMLLLQVGVLYVFSLVGTWIQGVFHLSMPGSLIGMLMLFLLLSTRILPLKWFEEATIGSVTMIVTGILISIFIPYGT
KFIF
>Mature_84_residues
MKYVMLLLQVGVLYVFSLVGTWIQGVFHLSMPGSLIGMLMLFLLLSTRILPLKWFEEATIGSVTMIVTGILISIFIPYGT
KFIF

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 9460; Mature: 9460

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYVMLLLQVGVLYVFSLVGTWIQGVFHLSMPGSLIGMLMLFLLLSTRILPLKWFEEATI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GSVTMIVTGILISIFIPYGTKFIF
HHHHHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MKYVMLLLQVGVLYVFSLVGTWIQGVFHLSMPGSLIGMLMLFLLLSTRILPLKWFEEATI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GSVTMIVTGILISIFIPYGTKFIF
HHHHHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]