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The map label for this gene is sucC [H]

Identifier: 49476305

GI number: 49476305

Start: 1913168

End: 1914364

Strand: Reverse

Name: sucC [H]

Synonym: BH16560

Alternate gene names: 49476305

Gene position: 1914364-1913168 (Counterclockwise)

Preceding gene: 49476306

Following gene: 49476304

Centisome position: 99.14

GC content: 40.94

Gene sequence:

>1197_bases
ATGAATATCCATGAATATCAGGCCAAACGTCTGCTTCATGAATATGGAGCACCAATTGCAAATGGTGTTGCTGTTTATTC
TGTAGAGCAAGCTGAAAAATGGGCAAAAAAATTGCCCGGGCCACTCTATGTGGTTAAAAGTCAGATTCACGCTGGTGGTC
GTGGTAAAGGGAAGTTTAAAGAACTAGATCCTGATGCAAAAGGTGGTGTTCGACTTGCAAAATCCGTTGAAGAAGTCGTT
GCAAATGTGAAAGAGATGCTTGGTAAAACTTTGGTCACTAAGCAAACGGGACCAGAGGGTAAGCAAGTCAATCGCCTTTA
TATTGAAGATGGTGCTGATATCGAACGGGAGCTTTATCTTTCGCTTTTGGTTGATCGTAACGTTGGTCGAGTGGCTTTTG
TTGTTTCAACAGAGGGGGGAATGGATATTGAAACAGTGGCTGAAGAAACACCAGAAAAAATATTAACTCTCCCCATTAAC
TCTACCCAAGGTGTTACTTCTTCCGATTGTGCAAGGCTTTGTGATGCATTGGATTTACACGATAGTGCACGAGAAGATGG
TGAAAAACTTTTCCCAATTCTCTATAAAGCGTTTTGTGAAAAAGATATGAGCCTTCTTGAAATCAATCCGCTTATTGTGA
TGACAAATGGTCATTTGCGTGTTCTTGATGCAAAAGTTTCTTTTGATAATAATGCTCTATTTCGTCATCCAGACATTTTA
GAGTTGCGCGATACTTCAGAAGAAGATCCAAAAGAGATTGAAGCATCAAAGCATGATCTTGCTTATGTTGCTCTTGAGGG
CACAATTGGTTGTATGGTCAATGGTGCAGGTCTTGCTATGGCAACAATGGATATCATTAAGCTTTATGGAGCTGAACCAG
CAAATTTCCTTGATGTTGGTGGTGGAGCTTCAAAAGAAAAAGTAACCGCTGCTTTTAAGATTATCACTGCTGATCCAAAT
GTTAAGGGCATTTTGGTTAATATTTTTGGTGGAATTATGCGTTGTGATGTCATTGCTGAGGGTGTGGTTGCTGCTGTTCG
GGAAGTTGGTTTAAAGGTTCCTTTGGTTGTTCGTCTTGAAGGCACGAATGTTGAGCAGGGGAAAGCGATTATCAGTGATA
GTGGTCTGAACGTTATTCCTGCTGATGATTTAGATGATGCTGCTCAAAAAATTGTTGCAGCCGTGAAGGGAGCTTAA

Upstream 100 bases:

>100_bases
AATAACTCAAGCAAGACCCTGTTCATTAAAACAGAATATTTAAAAATATTATGACGATTCAAAGATTAATTTAAGATCCA
TAAAAGAAAAGGACAAGTGA

Downstream 100 bases:

>100_bases
GCTATGTCAATTCTTGTGAATAAAGATACGAAAGTTCTCGTTCAAGGGCTTACAGGAAAAACAGGAACTTTTCATACAGA
ACAAGCGCTTGCTTATCATG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNIHEYQAKRLLHEYGAPIANGVAVYSVEQAEKWAKKLPGPLYVVKSQIHAGGRGKGKFKELDPDAKGGVRLAKSVEEVV
ANVKEMLGKTLVTKQTGPEGKQVNRLYIEDGADIERELYLSLLVDRNVGRVAFVVSTEGGMDIETVAEETPEKILTLPIN
STQGVTSSDCARLCDALDLHDSAREDGEKLFPILYKAFCEKDMSLLEINPLIVMTNGHLRVLDAKVSFDNNALFRHPDIL
ELRDTSEEDPKEIEASKHDLAYVALEGTIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPN
VKGILVNIFGGIMRCDVIAEGVVAAVREVGLKVPLVVRLEGTNVEQGKAIISDSGLNVIPADDLDDAAQKIVAAVKGA

Sequences:

>Translated_398_residues
MNIHEYQAKRLLHEYGAPIANGVAVYSVEQAEKWAKKLPGPLYVVKSQIHAGGRGKGKFKELDPDAKGGVRLAKSVEEVV
ANVKEMLGKTLVTKQTGPEGKQVNRLYIEDGADIERELYLSLLVDRNVGRVAFVVSTEGGMDIETVAEETPEKILTLPIN
STQGVTSSDCARLCDALDLHDSAREDGEKLFPILYKAFCEKDMSLLEINPLIVMTNGHLRVLDAKVSFDNNALFRHPDIL
ELRDTSEEDPKEIEASKHDLAYVALEGTIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPN
VKGILVNIFGGIMRCDVIAEGVVAAVREVGLKVPLVVRLEGTNVEQGKAIISDSGLNVIPADDLDDAAQKIVAAVKGA
>Mature_398_residues
MNIHEYQAKRLLHEYGAPIANGVAVYSVEQAEKWAKKLPGPLYVVKSQIHAGGRGKGKFKELDPDAKGGVRLAKSVEEVV
ANVKEMLGKTLVTKQTGPEGKQVNRLYIEDGADIERELYLSLLVDRNVGRVAFVVSTEGGMDIETVAEETPEKILTLPIN
STQGVTSSDCARLCDALDLHDSAREDGEKLFPILYKAFCEKDMSLLEINPLIVMTNGHLRVLDAKVSFDNNALFRHPDIL
ELRDTSEEDPKEIEASKHDLAYVALEGTIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPN
VKGILVNIFGGIMRCDVIAEGVVAAVREVGLKVPLVVRLEGTNVEQGKAIISDSGLNVIPADDLDDAAQKIVAAVKGA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=44.3877551020408, Blast_Score=343, Evalue=1e-94,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=44.8186528497409, Blast_Score=324, Evalue=7e-89,
Organism=Homo sapiens, GI294862256, Length=366, Percent_Identity=44.8087431693989, Blast_Score=305, Evalue=4e-83,
Organism=Escherichia coli, GI1786948, Length=397, Percent_Identity=52.1410579345088, Blast_Score=383, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=44.5569620253165, Blast_Score=343, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17567829, Length=391, Percent_Identity=44.5012787723785, Blast_Score=333, Evalue=6e-92,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=45.0632911392405, Blast_Score=342, Evalue=7e-95,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=48.8664987405542, Blast_Score=355, Evalue=3e-98,
Organism=Drosophila melanogaster, GI161078106, Length=388, Percent_Identity=46.1340206185567, Blast_Score=338, Evalue=4e-93,
Organism=Drosophila melanogaster, GI24645208, Length=388, Percent_Identity=46.1340206185567, Blast_Score=338, Evalue=4e-93,
Organism=Drosophila melanogaster, GI281361397, Length=389, Percent_Identity=46.2724935732648, Blast_Score=337, Evalue=6e-93,
Organism=Drosophila melanogaster, GI281361395, Length=389, Percent_Identity=46.2724935732648, Blast_Score=337, Evalue=6e-93,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42818; Mature: 42818

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKRLLHEYGAPIANGVAVYSVEQAEKWAKKLPGPLYVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCHHCCEEEEEHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCCCC
ELDPDAKGGVRLAKSVEEVVANVKEMLGKTLVTKQTGPEGKQVNRLYIEDGADIERELYL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEEEECCCCHHHHHHH
SLLVDRNVGRVAFVVSTEGGMDIETVAEETPEKILTLPINSTQGVTSSDCARLCDALDLH
HHEEECCCCEEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCC
DSAREDGEKLFPILYKAFCEKDMSLLEINPLIVMTNGHLRVLDAKVSFDNNALFRHPDIL
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCEEEEEEEEECCCCEEECCCCCE
ELRDTSEEDPKEIEASKHDLAYVALEGTIGCMVNGAGLAMATMDIIKLYGAEPANFLDVG
EECCCCCCCCHHHHCCCCCEEEEEEECCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGASKEKVTAAFKIITADPNVKGILVNIFGGIMRCDVIAEGVVAAVREVGLKVPLVVRLE
CCCCCCEEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GTNVEQGKAIISDSGLNVIPADDLDDAAQKIVAAVKGA
CCCCCCCCEEEECCCCEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIHEYQAKRLLHEYGAPIANGVAVYSVEQAEKWAKKLPGPLYVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCHHCCEEEEEHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCCCC
ELDPDAKGGVRLAKSVEEVVANVKEMLGKTLVTKQTGPEGKQVNRLYIEDGADIERELYL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEEEEECCCCHHHHHHH
SLLVDRNVGRVAFVVSTEGGMDIETVAEETPEKILTLPINSTQGVTSSDCARLCDALDLH
HHEEECCCCEEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCC
DSAREDGEKLFPILYKAFCEKDMSLLEINPLIVMTNGHLRVLDAKVSFDNNALFRHPDIL
HHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEECCCEEEEEEEEECCCCEEECCCCCE
ELRDTSEEDPKEIEASKHDLAYVALEGTIGCMVNGAGLAMATMDIIKLYGAEPANFLDVG
EECCCCCCCCHHHHCCCCCEEEEEEECCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGASKEKVTAAFKIITADPNVKGILVNIFGGIMRCDVIAEGVVAAVREVGLKVPLVVRLE
CCCCCCEEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GTNVEQGKAIISDSGLNVIPADDLDDAAQKIVAAVKGA
CCCCCCCCEEEECCCCEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA