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The map label for this gene is gap [H]

Identifier: 49476165

GI number: 49476165

Start: 1729788

End: 1730795

Strand: Reverse

Name: gap [H]

Synonym: BH15080

Alternate gene names: 49476165

Gene position: 1730795-1729788 (Counterclockwise)

Preceding gene: 49476166

Following gene: 49476164

Centisome position: 89.63

GC content: 43.55

Gene sequence:

>1008_bases
ATGAGTGTTCGCGTTGCAATTAATGGGTTTGGGCGTATCGGACGCAATATTTTGCGTGCCATTATCGAAAGTGGACGACA
AGATATTGAAGTTGTGGCCCTTAATGATTTAGGATCGGTGGAAACCAATGCCCATTTGTTGCGCTATGATTCTGTTCATG
GATGTTTCCCTGGCACTGTTCAAGTTGTTGGTGATGCCATTGATATCGGTTCTAGTTTGATAAAAGTGTTTGCAGAGCGT
GATCCAGCACAATTGCCTTGGAAGGCTTTGGATATTGATATTGCTTTGGAGTGTACAGGTATTTTTACCGCTCGTGACAA
AGCAAGTGCCCACTTGGATGCGGGGGCAAAGCGTGTTCTTGTTTCTGCACCCTCAGAAGGCGCAGATCTTACTGTGGTTT
ATGGAGTAAATCATCAGTTTTTGAGCAAAGAACACCATGTTATTTCGAATGCTTCTTGCACAACCAACTGTTTGGCGCCT
GTTGCACAAGTTTTGCACAACACTGTTGGCATTGAAAAGGGCTTTATGACAACAATCCATTCTTATACGGGCGATCAACC
TGTGTTGGATACAATGCATCGTGACCTTTATCGTGCACGTGCGGCGGCTCTTTCTATGATCCCTACCTCAACAGGGGCAG
CGAAAGCTGTGGGATTGGTTTTGCCAGAATTAAAAGGATTGCTTGATGGGGTGTCGATTCGCGTTCCAACGCCGAATGTT
TCCGTTGTTGATTTGACGTTTACTGCTAAGCGTTCCACAACGATTGAAGAAATTAATACTGCTATTCGTACTGCTGCACA
GGGGTCACTCAAGGGAATTTTAGACTATACTGACGAAAAGCTCGTGAGTTGTGATTTTAACCATAATCCACATTCTGCTA
TTTTTCATAATGATCAAACCAAGGTCATTGATGGTCAACTTTGTCGTGTTCTGGTTTGGTATGATAATGAATGGGGTTTC
TCAAACCGCATGTGTGATACGGCTGTGGCTTTTGCTAAAACAATATAA

Upstream 100 bases:

>100_bases
GGATGACAGGATCTTAAGGTTATAGAAGTGAATGATTTTTAGATGCTTGAAACCAATACCCATGTGTTGTGCTATGAAAA
ATTGATAAGGAAAATATGAA

Downstream 100 bases:

>100_bases
AATGAGAGGTCCTTCAGGTCCTCTTTTTATAAAAAAAAGTCAAGTGTATGATAAAATGAAAGTGCATTCTTTTTTAAAAA
AACGAATCAAGACTTCTTTT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSVRVAINGFGRIGRNILRAIIESGRQDIEVVALNDLGSVETNAHLLRYDSVHGCFPGTVQVVGDAIDIGSSLIKVFAER
DPAQLPWKALDIDIALECTGIFTARDKASAHLDAGAKRVLVSAPSEGADLTVVYGVNHQFLSKEHHVISNASCTTNCLAP
VAQVLHNTVGIEKGFMTTIHSYTGDQPVLDTMHRDLYRARAAALSMIPTSTGAAKAVGLVLPELKGLLDGVSIRVPTPNV
SVVDLTFTAKRSTTIEEINTAIRTAAQGSLKGILDYTDEKLVSCDFNHNPHSAIFHNDQTKVIDGQLCRVLVWYDNEWGF
SNRMCDTAVAFAKTI

Sequences:

>Translated_335_residues
MSVRVAINGFGRIGRNILRAIIESGRQDIEVVALNDLGSVETNAHLLRYDSVHGCFPGTVQVVGDAIDIGSSLIKVFAER
DPAQLPWKALDIDIALECTGIFTARDKASAHLDAGAKRVLVSAPSEGADLTVVYGVNHQFLSKEHHVISNASCTTNCLAP
VAQVLHNTVGIEKGFMTTIHSYTGDQPVLDTMHRDLYRARAAALSMIPTSTGAAKAVGLVLPELKGLLDGVSIRVPTPNV
SVVDLTFTAKRSTTIEEINTAIRTAAQGSLKGILDYTDEKLVSCDFNHNPHSAIFHNDQTKVIDGQLCRVLVWYDNEWGF
SNRMCDTAVAFAKTI
>Mature_334_residues
SVRVAINGFGRIGRNILRAIIESGRQDIEVVALNDLGSVETNAHLLRYDSVHGCFPGTVQVVGDAIDIGSSLIKVFAERD
PAQLPWKALDIDIALECTGIFTARDKASAHLDAGAKRVLVSAPSEGADLTVVYGVNHQFLSKEHHVISNASCTTNCLAPV
AQVLHNTVGIEKGFMTTIHSYTGDQPVLDTMHRDLYRARAAALSMIPTSTGAAKAVGLVLPELKGLLDGVSIRVPTPNVS
VVDLTFTAKRSTTIEEINTAIRTAAQGSLKGILDYTDEKLVSCDFNHNPHSAIFHNDQTKVIDGQLCRVLVWYDNEWGFS
NRMCDTAVAFAKTI

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=326, Percent_Identity=46.0122699386503, Blast_Score=295, Evalue=5e-80,
Organism=Homo sapiens, GI7657116, Length=325, Percent_Identity=44, Blast_Score=275, Evalue=5e-74,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=49.7005988023952, Blast_Score=338, Evalue=2e-94,
Organism=Escherichia coli, GI1788079, Length=327, Percent_Identity=45.2599388379205, Blast_Score=299, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17534679, Length=330, Percent_Identity=47.5757575757576, Blast_Score=307, Evalue=4e-84,
Organism=Caenorhabditis elegans, GI17534677, Length=330, Percent_Identity=47.2727272727273, Blast_Score=306, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI32566163, Length=330, Percent_Identity=46.969696969697, Blast_Score=294, Evalue=5e-80,
Organism=Caenorhabditis elegans, GI17568413, Length=330, Percent_Identity=46.969696969697, Blast_Score=293, Evalue=6e-80,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=47.4474474474475, Blast_Score=312, Evalue=6e-86,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=47.4474474474475, Blast_Score=308, Evalue=6e-85,
Organism=Saccharomyces cerevisiae, GI6321631, Length=333, Percent_Identity=46.8468468468468, Blast_Score=304, Evalue=1e-83,
Organism=Drosophila melanogaster, GI85725000, Length=325, Percent_Identity=47.0769230769231, Blast_Score=294, Evalue=6e-80,
Organism=Drosophila melanogaster, GI22023983, Length=325, Percent_Identity=47.0769230769231, Blast_Score=294, Evalue=6e-80,
Organism=Drosophila melanogaster, GI17933600, Length=325, Percent_Identity=47.0769230769231, Blast_Score=292, Evalue=2e-79,
Organism=Drosophila melanogaster, GI18110149, Length=325, Percent_Identity=47.0769230769231, Blast_Score=292, Evalue=2e-79,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=41.5384615384615, Blast_Score=258, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36178; Mature: 36046

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRVAINGFGRIGRNILRAIIESGRQDIEVVALNDLGSVETNAHLLRYDSVHGCFPGTV
CEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCHH
QVVGDAIDIGSSLIKVFAERDPAQLPWKALDIDIALECTGIFTARDKASAHLDAGAKRVL
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEEEEEEECCCCCHHHCCCCCEEE
VSAPSEGADLTVVYGVNHQFLSKEHHVISNASCTTNCLAPVAQVLHNTVGIEKGFMTTIH
EECCCCCCCEEEEEECCHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
SYTGDQPVLDTMHRDLYRARAAALSMIPTSTGAAKAVGLVLPELKGLLDGVSIRVPTPNV
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCC
SVVDLTFTAKRSTTIEEINTAIRTAAQGSLKGILDYTDEKLVSCDFNHNPHSAIFHNDQT
EEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEEECCCCCCCEEEECCCC
KVIDGQLCRVLVWYDNEWGFSNRMCDTAVAFAKTI
EEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SVRVAINGFGRIGRNILRAIIESGRQDIEVVALNDLGSVETNAHLLRYDSVHGCFPGTV
EEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCHH
QVVGDAIDIGSSLIKVFAERDPAQLPWKALDIDIALECTGIFTARDKASAHLDAGAKRVL
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEEEEEEECCCCCHHHCCCCCEEE
VSAPSEGADLTVVYGVNHQFLSKEHHVISNASCTTNCLAPVAQVLHNTVGIEKGFMTTIH
EECCCCCCCEEEEEECCHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
SYTGDQPVLDTMHRDLYRARAAALSMIPTSTGAAKAVGLVLPELKGLLDGVSIRVPTPNV
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCC
SVVDLTFTAKRSTTIEEINTAIRTAAQGSLKGILDYTDEKLVSCDFNHNPHSAIFHNDQT
EEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEEECCCCCCCEEEECCCC
KVIDGQLCRVLVWYDNEWGFSNRMCDTAVAFAKTI
EEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]