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The map label for this gene is murA

Identifier: 49476104

GI number: 49476104

Start: 1649529

End: 1650824

Strand: Reverse

Name: murA

Synonym: BH14420

Alternate gene names: 49476104

Gene position: 1650824-1649529 (Counterclockwise)

Preceding gene: 49476105

Following gene: 49476098

Centisome position: 85.49

GC content: 44.29

Gene sequence:

>1296_bases
ATGGATTCTATTGAAATTGTTGGGGGAAAAAAACTTAAAGGTATCATTCCTATCTCAGGGGCAAAAAATGCTGCATTGCC
TCTTATGATTGCTGCTTTGCTTACAGAAGAAACCCTTTCTTTAGACAATATCCCCCATCTTGCTGATATCGAACTGCTCA
TTCGTATCCTCAATAATCACGGTGTCGGATATGCTGTCGATGGGCAAAAAAACCATACCGAATGTGTTCATTCAAGAACA
ATTCATTTTACGGCACAAAAAATAACCACAACATATGCACCATACGATCTCGTTCGAAAAATGCGCGCAAGCTTTTGGGT
CATCGGCCCACTGCTCGCACGATGCCGAGAGGCCTATGTTTCACTGCCAGGAGGATGCGCTATCGGAACAAGACCCGTTG
ATTTTATCCTCGAGGGGCTCAAAACTTTAGGCGCACGTATTACTATCGAAAATGGATATGTCCATGCTAAGGTCCCAAAA
GGATTAAAAGGTGCGCACTATCGTTTTCCTAAAGTCACTGTCGGCGGAACACATGTTATGATCATGGCTGCTGTAACCGC
AAATGGAAAAACCGTCCTCGAAAATGCTGCTTGTGAACCTGAAGTGACAAACCTTGTTCAAGCCCTTAATGCAATGGGCG
CAAAAATAACCGGTGAAGGAACAACAATTCTTACCATCGAAGGCGTTCAAAAACTTAACGGAGCAAGAATATCTGTCATC
CCTGACCGAATTGAAGCCGGAACTTATGCAATGGCTGTTGCTATGACTGGGGGGGATGTGATGCTCAAAAATGCTAACCC
TCACCATCTTACACAAGTGCTTGAGATCCTCCAAAAAACTGGACTTGATATCGAAATCAAACCTCAAGGAATTCATCTTA
AAAGAAATTTACGCCAAACAAAAATAATGCCCGTTGATATTAAAACAGGTCCTTATCCGGCTTTTCCAACGGATCTCCAA
GCCCAATTCATGGCTCTGATGACCCGCGCTCAGGGAATCTCTCATATTACCGAAACAATTTTCGAAAATCGCTTTATGCA
TGTGCAGGAACTCAATCGTTTGGGTGCGCAAATAAAGCTCGATGGTCAGACGGCAACCGTCTTTGGAACAGAGCACCTAC
AAGGTGCGCCGGTAATGGCAACCGATTTGCGTGCTTCTGTCTCTCTTGTGATTGCTGCACTCGCTGCAAAGGGAAAAACG
ACCGTTAATCGCGTGTATCATCTTGATCGTGGGTTTGAAAGGTTGGAAGAAAAATTAGCACGCTGTGGGGCTACCATTCA
ACGCATCACAGTATAA

Upstream 100 bases:

>100_bases
CTAAAGTTTGGAATTCGTTCTAAAACCATAACAAACAATAAATTCCCAAGAGGGCAAAAGCTTTCGAAGGGGAAACGCAA
AGCAAAAGAGGGAAAGTTCT

Downstream 100 bases:

>100_bases
TTTCCTCTCTACTCTCTTCACCCCCCTTCGGGGGGTAGAGGGTTCTCCTTGTTTAGGTGTCGTTTCTTCAAGCTCTCTCT
CCTACTTTCGATGACTTTTC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MDSIEIVGGKKLKGIIPISGAKNAALPLMIAALLTEETLSLDNIPHLADIELLIRILNNHGVGYAVDGQKNHTECVHSRT
IHFTAQKITTTYAPYDLVRKMRASFWVIGPLLARCREAYVSLPGGCAIGTRPVDFILEGLKTLGARITIENGYVHAKVPK
GLKGAHYRFPKVTVGGTHVMIMAAVTANGKTVLENAACEPEVTNLVQALNAMGAKITGEGTTILTIEGVQKLNGARISVI
PDRIEAGTYAMAVAMTGGDVMLKNANPHHLTQVLEILQKTGLDIEIKPQGIHLKRNLRQTKIMPVDIKTGPYPAFPTDLQ
AQFMALMTRAQGISHITETIFENRFMHVQELNRLGAQIKLDGQTATVFGTEHLQGAPVMATDLRASVSLVIAALAAKGKT
TVNRVYHLDRGFERLEEKLARCGATIQRITV

Sequences:

>Translated_431_residues
MDSIEIVGGKKLKGIIPISGAKNAALPLMIAALLTEETLSLDNIPHLADIELLIRILNNHGVGYAVDGQKNHTECVHSRT
IHFTAQKITTTYAPYDLVRKMRASFWVIGPLLARCREAYVSLPGGCAIGTRPVDFILEGLKTLGARITIENGYVHAKVPK
GLKGAHYRFPKVTVGGTHVMIMAAVTANGKTVLENAACEPEVTNLVQALNAMGAKITGEGTTILTIEGVQKLNGARISVI
PDRIEAGTYAMAVAMTGGDVMLKNANPHHLTQVLEILQKTGLDIEIKPQGIHLKRNLRQTKIMPVDIKTGPYPAFPTDLQ
AQFMALMTRAQGISHITETIFENRFMHVQELNRLGAQIKLDGQTATVFGTEHLQGAPVMATDLRASVSLVIAALAAKGKT
TVNRVYHLDRGFERLEEKLARCGATIQRITV
>Mature_431_residues
MDSIEIVGGKKLKGIIPISGAKNAALPLMIAALLTEETLSLDNIPHLADIELLIRILNNHGVGYAVDGQKNHTECVHSRT
IHFTAQKITTTYAPYDLVRKMRASFWVIGPLLARCREAYVSLPGGCAIGTRPVDFILEGLKTLGARITIENGYVHAKVPK
GLKGAHYRFPKVTVGGTHVMIMAAVTANGKTVLENAACEPEVTNLVQALNAMGAKITGEGTTILTIEGVQKLNGARISVI
PDRIEAGTYAMAVAMTGGDVMLKNANPHHLTQVLEILQKTGLDIEIKPQGIHLKRNLRQTKIMPVDIKTGPYPAFPTDLQ
AQFMALMTRAQGISHITETIFENRFMHVQELNRLGAQIKLDGQTATVFGTEHLQGAPVMATDLRASVSLVIAALAAKGKT
TVNRVYHLDRGFERLEEKLARCGATIQRITV

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=429, Percent_Identity=47.5524475524476, Blast_Score=400, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_BARHE (Q6G226)

Other databases:

- EMBL:   BX897699
- RefSeq:   YP_034145.1
- ProteinModelPortal:   Q6G226
- SMR:   Q6G226
- GeneID:   2865361
- GenomeReviews:   BX897699_GR
- KEGG:   bhe:BH14420
- NMPDR:   fig|283166.1.peg.1273
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   Q6G226
- ProtClustDB:   PRK09369
- BioCyc:   BHEN283166:BH14420-MONOMER
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 46719; Mature: 46719

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSIEIVGGKKLKGIIPISGAKNAALPLMIAALLTEETLSLDNIPHLADIELLIRILNNH
CCCEEEECCCEECEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
GVGYAVDGQKNHTECVHSRTIHFTAQKITTTYAPYDLVRKMRASFWVIGPLLARCREAYV
CCEEEECCCCCCHHHHHCCEEEEEEEHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLPGGCAIGTRPVDFILEGLKTLGARITIENGYVHAKVPKGLKGAHYRFPKVTVGGTHVM
CCCCCCEECCCHHHHHHHHHHHCCCEEEEECCEEEEECCCCCCCCCEECCEEEECCCEEE
IMAAVTANGKTVLENAACEPEVTNLVQALNAMGAKITGEGTTILTIEGVQKLNGARISVI
EEEEEECCCCEEECCCCCCHHHHHHHHHHHHCCCEEECCCEEEEEEECHHHCCCCEEEEE
PDRIEAGTYAMAVAMTGGDVMLKNANPHHLTQVLEILQKTGLDIEIKPQGIHLKRNLRQT
CCCCCCCCEEEEEEEECCEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCEEHHCCCCCC
KIMPVDIKTGPYPAFPTDLQAQFMALMTRAQGISHITETIFENRFMHVQELNRLGAQIKL
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEE
DGQTATVFGTEHLQGAPVMATDLRASVSLVIAALAAKGKTTVNRVYHLDRGFERLEEKLA
CCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RCGATIQRITV
HHCCHHHEECC
>Mature Secondary Structure
MDSIEIVGGKKLKGIIPISGAKNAALPLMIAALLTEETLSLDNIPHLADIELLIRILNNH
CCCEEEECCCEECEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
GVGYAVDGQKNHTECVHSRTIHFTAQKITTTYAPYDLVRKMRASFWVIGPLLARCREAYV
CCEEEECCCCCCHHHHHCCEEEEEEEHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLPGGCAIGTRPVDFILEGLKTLGARITIENGYVHAKVPKGLKGAHYRFPKVTVGGTHVM
CCCCCCEECCCHHHHHHHHHHHCCCEEEEECCEEEEECCCCCCCCCEECCEEEECCCEEE
IMAAVTANGKTVLENAACEPEVTNLVQALNAMGAKITGEGTTILTIEGVQKLNGARISVI
EEEEEECCCCEEECCCCCCHHHHHHHHHHHHCCCEEECCCEEEEEEECHHHCCCCEEEEE
PDRIEAGTYAMAVAMTGGDVMLKNANPHHLTQVLEILQKTGLDIEIKPQGIHLKRNLRQT
CCCCCCCCEEEEEEEECCEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCEEHHCCCCCC
KIMPVDIKTGPYPAFPTDLQAQFMALMTRAQGISHITETIFENRFMHVQELNRLGAQIKL
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEE
DGQTATVFGTEHLQGAPVMATDLRASVSLVIAALAAKGKTTVNRVYHLDRGFERLEEKLA
CCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RCGATIQRITV
HHCCHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA