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The map label for this gene is arrD [H]

Identifier: 49476058

GI number: 49476058

Start: 1602076

End: 1602738

Strand: Reverse

Name: arrD [H]

Synonym: BH13940

Alternate gene names: 49476058

Gene position: 1602738-1602076 (Counterclockwise)

Preceding gene: 49476059

Following gene: 49476057

Centisome position: 83.0

GC content: 41.18

Gene sequence:

>663_bases
ATGCGAAAAATTTCAAAAGAGGGACTTCTACTCATTAAACAATGGGAAGGACTCCATTTGCACGCTTATCAAGATGCCGT
TGGTGTATGGACAATCGGTTATGGACATACCACTCAAGTGGGCGAGCCTTCTGTGCAGGAAGGAATGCAGATTACTGTTG
CTGAAGCGGAAACTCTCTTACAAAAAGATCTCGCAAAATTTGAAAAAACTGTCGAAGAGATGGTGGAGCAACCCTTAAAT
GATGAGCAGTTTGCTACTCTTGTGTCTTTTTGCTATAATGTCGGAATAGAAACTTTTTGTAATTCTACACTCTTAAAAAA
ACTTAATAAAGGGAAGTATGAAGCTGTGCCGGCTGAATTGCAAAAATGGACCAGAGCAGGAGGAAAATGCTTACAGGGAC
TCGTAAATCGCCGAGCTGCTGAAGCAGGTTTGTGGGTTAAGGGTGCTTATGTTTCTTCCAATTATCAACAAGTCGAAATA
CCTCAAAATTCTTTTTGGGGAAAGATAGAAGTTTTAGCGCCAATCATTGGTTCATTTTCAGGGTTAACAGGGATTTTAAC
GGGACAGGGACCTATACAATGGGCTTTAGCCGTGGTTATGGTTTTGGCTACAATCGCCGCTATTGGGATGTCTGTCTATC
GGATGAAAGAAGAGTATTCATAA

Upstream 100 bases:

>100_bases
GGGGACGCTCCTGGAGATGGGGTATGTGGTAAGTAATCGTCATGCCTTGTATTCCTATTTTATTTTTATATGTCCTAGGT
GATTTGAGGAGTTTTAAAGA

Downstream 100 bases:

>100_bases
CTTTTTTCTCTCGTGAGAGTTTTCTTGTCTTCTTTATGCTTGGTGCTGCGTTGAGCAGCTTTTTTATGGACGCTTTTTTA
CGCCCAATAACTTTGATCCA

Product: phage related lysozyme

Products: NA

Alternate protein names: Endolysin; Lysis protein; Muramidase [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MRKISKEGLLLIKQWEGLHLHAYQDAVGVWTIGYGHTTQVGEPSVQEGMQITVAEAETLLQKDLAKFEKTVEEMVEQPLN
DEQFATLVSFCYNVGIETFCNSTLLKKLNKGKYEAVPAELQKWTRAGGKCLQGLVNRRAAEAGLWVKGAYVSSNYQQVEI
PQNSFWGKIEVLAPIIGSFSGLTGILTGQGPIQWALAVVMVLATIAAIGMSVYRMKEEYS

Sequences:

>Translated_220_residues
MRKISKEGLLLIKQWEGLHLHAYQDAVGVWTIGYGHTTQVGEPSVQEGMQITVAEAETLLQKDLAKFEKTVEEMVEQPLN
DEQFATLVSFCYNVGIETFCNSTLLKKLNKGKYEAVPAELQKWTRAGGKCLQGLVNRRAAEAGLWVKGAYVSSNYQQVEI
PQNSFWGKIEVLAPIIGSFSGLTGILTGQGPIQWALAVVMVLATIAAIGMSVYRMKEEYS
>Mature_220_residues
MRKISKEGLLLIKQWEGLHLHAYQDAVGVWTIGYGHTTQVGEPSVQEGMQITVAEAETLLQKDLAKFEKTVEEMVEQPLN
DEQFATLVSFCYNVGIETFCNSTLLKKLNKGKYEAVPAELQKWTRAGGKCLQGLVNRRAAEAGLWVKGAYVSSNYQQVEI
PQNSFWGKIEVLAPIIGSFSGLTGILTGQGPIQWALAVVMVLATIAAIGMSVYRMKEEYS

Specific function: Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity [H]

COG id: COG3772

COG function: function code R; Phage-related lysozyme (muraminidase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 24 family [H]

Homologues:

Organism=Escherichia coli, GI1786768, Length=126, Percent_Identity=38.8888888888889, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002196 [H]

Pfam domain/function: PF00959 Phage_lysozyme [H]

EC number: =3.2.1.17 [H]

Molecular weight: Translated: 24302; Mature: 24302

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKISKEGLLLIKQWEGLHLHAYQDAVGVWTIGYGHTTQVGEPSVQEGMQITVAEAETLL
CCCCCCCCEEEEEECCCCEEEEECCCCEEEEECCCCCCCCCCCHHHCCCEEEHHHHHHHH
QKDLAKFEKTVEEMVEQPLNDEQFATLVSFCYNVGIETFCNSTLLKKLNKGKYEAVPAEL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHH
QKWTRAGGKCLQGLVNRRAAEAGLWVKGAYVSSNYQQVEIPQNSFWGKIEVLAPIIGSFS
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHC
GLTGILTGQGPIQWALAVVMVLATIAAIGMSVYRMKEEYS
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKISKEGLLLIKQWEGLHLHAYQDAVGVWTIGYGHTTQVGEPSVQEGMQITVAEAETLL
CCCCCCCCEEEEEECCCCEEEEECCCCEEEEECCCCCCCCCCCHHHCCCEEEHHHHHHHH
QKDLAKFEKTVEEMVEQPLNDEQFATLVSFCYNVGIETFCNSTLLKKLNKGKYEAVPAEL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHH
QKWTRAGGKCLQGLVNRRAAEAGLWVKGAYVSSNYQQVEIPQNSFWGKIEVLAPIIGSFS
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHC
GLTGILTGQGPIQWALAVVMVLATIAAIGMSVYRMKEEYS
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]