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The map label for this gene is mrp [H]

Identifier: 49475951

GI number: 49475951

Start: 1377828

End: 1378922

Strand: Reverse

Name: mrp [H]

Synonym: BH12380

Alternate gene names: 49475951

Gene position: 1378922-1377828 (Counterclockwise)

Preceding gene: 49475962

Following gene: 49475950

Centisome position: 71.41

GC content: 43.29

Gene sequence:

>1095_bases
GTGGTTTCTATCACAAGCGATGCTATTCGCAATGCGTTACATAAAGTTAAAGGACCGAATTTTGAAAGTGATATCGTATC
TTTGGGGCTTCTTTCAGAAATATTGGTTGTTCATGGCAAGGTTTTCTTTTCCATTACGGTTCCTGATGGACGTGTGCAAG
AATGGGAATCGTTGCGCCGTTCTGTCGAAGAAGTGGTCTCTGCTTTGGACGGGGTTGAAGCTGTTTTTGTCACACTTACG
ACAGAAAGAAGACCAGAGATGTCTTCTCAGTTGCAGAGAGATGAAGTTTTTTTTGCACCAAAACGGAGAGCAAATAGATT
GCTTGAGAAAATGCCGATAGAAGGTGTACGGCATGTGGTTGCGGTTGCTTCTGGAAAGGGGGGGGTTGGTAAATCTACAA
TGGCGATAAATATCGCTTTAGCTTTACAAGATTCTGGTTTCAAAACAGGTTTGATGGATGCGGATATTTATGGTCCTTCT
TTGCCACGTTTGACAGGACTTGTTAACCAAAAACCACAGTATATTGACGGGAAAAAGCTTCATCCTCTTGAAAAATTTGG
CCTTAAATTGATGTCGATGGGATTTTTGGTGGAGGAGGAAAATCCCGTGGTATGGCGTGGTCCCATGGTGATGGCTGCTG
TAACACAATTGCTAAGAGATGTTTTATGGGGGCCTCTTGACGTTTTGGTGGTTGATATGCCACCGGGTACAGGGGATGCT
CAATTGACGCTTGCTCAACAAGTACAGTTGACGGGGGCACTGATTGTTTCTACTCCGCAGGATCTTGCTTTAGTTGATGC
TCGTAAGGCGATGGAAATGTTCATGAAAGTCAATGTTCCCATTTTAGGACTCATTGAGAATATGAGTTATTTTATTGCTC
CTGATACAGGGAAACGCTACGATATTTTTGGTTATGGTGGTACGCGTGCAGAAGCCAGACGTCGAGGAGTCCCTTTCTTA
GCAGAAGTGCCGCTTGATGCAGCTTTACGATCTTCTTCAGATGACGGTATCCCCATCTTTGTTGCTAAGCCTGATGAGGA
GCATACTAAGCTTTATCGTTCGATTGTTGGGCAAATAAAAAACAAATTTTTTTAA

Upstream 100 bases:

>100_bases
CACTTTAATAAGGCGCATTAAAGTGGGAAATTTTGGATGATTAGTTTTAAATGCTGTCCTATTGTTGTGTTCGTTGGCAT
TTGTAGAGAGAGGGAAGGGC

Downstream 100 bases:

>100_bases
ATTTATCTTTTTCTCATAGGTTTTGCTAGGAGACAATCACTCAAAACATAAACAGTTGTTTTGTTGGTAACTGTAATGTG
CGAGTGTTTCATTGTTGCTG

Product: mrp protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MVSITSDAIRNALHKVKGPNFESDIVSLGLLSEILVVHGKVFFSITVPDGRVQEWESLRRSVEEVVSALDGVEAVFVTLT
TERRPEMSSQLQRDEVFFAPKRRANRLLEKMPIEGVRHVVAVASGKGGVGKSTMAINIALALQDSGFKTGLMDADIYGPS
LPRLTGLVNQKPQYIDGKKLHPLEKFGLKLMSMGFLVEEENPVVWRGPMVMAAVTQLLRDVLWGPLDVLVVDMPPGTGDA
QLTLAQQVQLTGALIVSTPQDLALVDARKAMEMFMKVNVPILGLIENMSYFIAPDTGKRYDIFGYGGTRAEARRRGVPFL
AEVPLDAALRSSSDDGIPIFVAKPDEEHTKLYRSIVGQIKNKFF

Sequences:

>Translated_364_residues
MVSITSDAIRNALHKVKGPNFESDIVSLGLLSEILVVHGKVFFSITVPDGRVQEWESLRRSVEEVVSALDGVEAVFVTLT
TERRPEMSSQLQRDEVFFAPKRRANRLLEKMPIEGVRHVVAVASGKGGVGKSTMAINIALALQDSGFKTGLMDADIYGPS
LPRLTGLVNQKPQYIDGKKLHPLEKFGLKLMSMGFLVEEENPVVWRGPMVMAAVTQLLRDVLWGPLDVLVVDMPPGTGDA
QLTLAQQVQLTGALIVSTPQDLALVDARKAMEMFMKVNVPILGLIENMSYFIAPDTGKRYDIFGYGGTRAEARRRGVPFL
AEVPLDAALRSSSDDGIPIFVAKPDEEHTKLYRSIVGQIKNKFF
>Mature_364_residues
MVSITSDAIRNALHKVKGPNFESDIVSLGLLSEILVVHGKVFFSITVPDGRVQEWESLRRSVEEVVSALDGVEAVFVTLT
TERRPEMSSQLQRDEVFFAPKRRANRLLEKMPIEGVRHVVAVASGKGGVGKSTMAINIALALQDSGFKTGLMDADIYGPS
LPRLTGLVNQKPQYIDGKKLHPLEKFGLKLMSMGFLVEEENPVVWRGPMVMAAVTQLLRDVLWGPLDVLVVDMPPGTGDA
QLTLAQQVQLTGALIVSTPQDLALVDARKAMEMFMKVNVPILGLIENMSYFIAPDTGKRYDIFGYGGTRAEARRRGVPFL
AEVPLDAALRSSSDDGIPIFVAKPDEEHTKLYRSIVGQIKNKFF

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=259, Percent_Identity=50.5791505791506, Blast_Score=254, Evalue=6e-68,
Organism=Homo sapiens, GI118572611, Length=269, Percent_Identity=39.0334572490706, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI6912540, Length=231, Percent_Identity=41.5584415584416, Blast_Score=178, Evalue=5e-45,
Organism=Escherichia coli, GI87082045, Length=252, Percent_Identity=48.015873015873, Blast_Score=256, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI25143050, Length=257, Percent_Identity=37.3540856031128, Blast_Score=167, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6322188, Length=222, Percent_Identity=39.6396396396396, Blast_Score=182, Evalue=8e-47,
Organism=Saccharomyces cerevisiae, GI6321347, Length=256, Percent_Identity=35.15625, Blast_Score=160, Evalue=4e-40,
Organism=Drosophila melanogaster, GI221511043, Length=260, Percent_Identity=40.3846153846154, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI24667611, Length=255, Percent_Identity=38.8235294117647, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI19921440, Length=235, Percent_Identity=37.4468085106383, Blast_Score=135, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR015223
- InterPro:   IPR002744
- InterPro:   IPR000808 [H]

Pfam domain/function: PF01883 DUF59; PF09140 MipZ; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 40016; Mature: 40016

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSITSDAIRNALHKVKGPNFESDIVSLGLLSEILVVHGKVFFSITVPDGRVQEWESLRR
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHH
SVEEVVSALDGVEAVFVTLTTERRPEMSSQLQRDEVFFAPKRRANRLLEKMPIEGVRHVV
HHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHEEECCHHHHHHHHHHCCHHHHHHEE
AVASGKGGVGKSTMAINIALALQDSGFKTGLMDADIYGPSLPRLTGLVNQKPQYIDGKKL
EEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCC
HPLEKFGLKLMSMGFLVEEENPVVWRGPMVMAAVTQLLRDVLWGPLDVLVVDMPPGTGDA
CCHHHHHHHHHHHCCEEECCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCC
QLTLAQQVQLTGALIVSTPQDLALVDARKAMEMFMKVNVPILGLIENMSYFIAPDTGKRY
EEEHHHHHEECCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEHCCCCEEEEECCCCCEE
DIFGYGGTRAEARRRGVPFLAEVPLDAALRSSSDDGIPIFVAKPDEEHTKLYRSIVGQIK
EEEECCCCHHHHHHCCCCEEEECCHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHH
NKFF
HCCC
>Mature Secondary Structure
MVSITSDAIRNALHKVKGPNFESDIVSLGLLSEILVVHGKVFFSITVPDGRVQEWESLRR
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHH
SVEEVVSALDGVEAVFVTLTTERRPEMSSQLQRDEVFFAPKRRANRLLEKMPIEGVRHVV
HHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHEEECCHHHHHHHHHHCCHHHHHHEE
AVASGKGGVGKSTMAINIALALQDSGFKTGLMDADIYGPSLPRLTGLVNQKPQYIDGKKL
EEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCC
HPLEKFGLKLMSMGFLVEEENPVVWRGPMVMAAVTQLLRDVLWGPLDVLVVDMPPGTGDA
CCHHHHHHHHHHHCCEEECCCCEEEECCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCC
QLTLAQQVQLTGALIVSTPQDLALVDARKAMEMFMKVNVPILGLIENMSYFIAPDTGKRY
EEEHHHHHEECCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEHCCCCEEEEECCCCCEE
DIFGYGGTRAEARRRGVPFLAEVPLDAALRSSSDDGIPIFVAKPDEEHTKLYRSIVGQIK
EEEECCCCHHHHHHCCCCEEEECCHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHHH
NKFF
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]